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Carl-Bertil Laurell
Carl-Bertil Laurell (born 28 June 1919 in Uppsala, dead 18 September 2001 in Malmö) was a Sweden, Swedish medical doctor and researcher. Laurell was Professor of clinical chemistry at Lund University. He named the blood plasma protein transferrin, and discovered that an inherited lack of Alpha 1-antitrypsin could lead to emphysema. In 1976, he was made a member of the Royal Swedish Academy of Sciences. Laurell received the Edwin F. Ullman Award from the American Association for Clinical Chemistry on May 4 in 2001. He was married to Anna-Britta Laurell, Professor of immunology at Lund university, from 1946 until her death in 2000. The couple had six children. He died on 18 September 2001. References 1919 births 2001 deaths 20th-century Swedish physicians Academic staff of Lund University Members of the Royal Swedish Academy of Sciences Swedish biochemists {{Chemist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uppsala
Uppsala (, or all ending in , ; archaically spelled ''Upsala'') is the county seat of Uppsala County and the List of urban areas in Sweden by population, fourth-largest city in Sweden, after Stockholm, Gothenburg, and Malmö. It had 177,074 inhabitants in 2019. Located north of the capital Stockholm it is also the seat of Uppsala Municipality. Since 1164, Uppsala has been the ecclesiology, ecclesiastical centre of Sweden, being the seat of the Archbishop of Uppsala, Archbishop of the Church of Sweden. Uppsala is home to Scandinavia's largest cathedral – Uppsala Cathedral, which was the frequent site of the coronation of the Swedish monarch until the late 19th century. Uppsala Castle, built by King Gustav I of Sweden, Gustav Vasa, served as one of the royal residences of the Swedish monarchs, and was expanded several times over its history, making Uppsala the secondary capital of Sweden during its Swedish Empire, greatest extent. Today it serves as the residence of the Gover ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malmö
Malmö (, ; da, Malmø ) is the largest city in the Swedish county (län) of Scania (Skåne). It is the third-largest city in Sweden, after Stockholm and Gothenburg, and the sixth-largest city in the Nordic region, with a municipal population of 350,647 in 2021. The Malmö Metropolitan Region is home to over 700,000 people, and the Øresund Region, which includes Malmö and Copenhagen, is home to 4 million people. Malmö was one of the earliest and most industrialised towns in Scandinavia, but it struggled to adapt to post-industrialism. Since the 2000 completion of the Öresund Bridge, Malmö has undergone a major transformation, producing new architectural developments, supporting new biotech and IT companies, and attracting students through Malmö University and other higher education facilities. Over time, Malmö's demographics have changed and by the turn of the 2020s almost half the municipal population had a foreign background. The city contains many histori ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sweden
Sweden, formally the Kingdom of Sweden,The United Nations Group of Experts on Geographical Names states that the country's formal name is the Kingdom of SwedenUNGEGN World Geographical Names, Sweden./ref> is a Nordic country located on the Scandinavian Peninsula in Northern Europe. It borders Norway to the west and north, Finland to the east, and is connected to Denmark in the southwest by a bridgetunnel across the Öresund. At , Sweden is the largest Nordic country, the third-largest country in the European Union, and the fifth-largest country in Europe. The capital and largest city is Stockholm. Sweden has a total population of 10.5 million, and a low population density of , with around 87% of Swedes residing in urban areas in the central and southern half of the country. Sweden has a nature dominated by forests and a large amount of lakes, including some of the largest in Europe. Many long rivers run from the Scandes range through the landscape, primarily ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Chemistry
Clinical chemistry (also known as chemical pathology, clinical biochemistry or medical biochemistry) is the area of chemistry that is generally concerned with analysis of bodily fluids for diagnostic and therapeutic purposes. It is an applied form of biochemistry (not to be confused with medicinal chemistry, which involves basic research for drug development). The discipline originated in the late 19th century with the use of simple chemical reaction tests for various components of blood and urine. In the many decades since, other techniques have been applied as science and technology have advanced, including the use and measurement of enzyme activities, spectrophotometry, electrophoresis, and immunoassay. There are now many blood tests and clinical urine tests with extensive diagnostic capabilities. Most current laboratories are now highly automated to accommodate the high workload typical of a hospital laboratory. Tests performed are closely monitored and quality controll ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lund University
, motto = Ad utrumque , mottoeng = Prepared for both , established = , type = Public research university , budget = SEK 9 billion Facts and figures Lund University web site. , head_label = , head = Erik Renström , academic_staff = 4,780 (2022) (academic staff, researchers and employed research students) , administrative_staff = 2,890 (2022) , students = 46 000 (29 000 full-time e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transferrin
Transferrins are glycoproteins found in vertebrates which bind to and consequently mediate the transport of iron (Fe) through blood plasma. They are produced in the liver and contain binding sites for two Fe3+ ions. Human transferrin is encoded by the ''TF'' gene and produced as a 76 kDa glycoprotein. Transferrin glycoproteins bind iron tightly, but reversibly. Although iron bound to transferrin is less than 0.1% (4 mg) of total body iron, it forms the most vital iron pool with the highest rate of turnover (25 mg/24 h). Transferrin has a molecular weight of around 80 kDa and contains two specific high-affinity Fe(III) binding sites. The affinity of transferrin for Fe(III) is extremely high (association constant is 1020 M−1 at pH 7.4) but decreases progressively with decreasing pH below neutrality. Transferrins are not limited to only binding to iron but also to different metal ions. These glycoproteins are located in various bodily fluids of vertebrates. Some inv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alpha 1-antitrypsin
Alpha-1 antitrypsin or α1-antitrypsin (A1AT, α1AT, A1A, or AAT) is a protein belonging to the serpin superfamily. It is encoded in humans by the ''SERPINA1'' gene. A protease inhibitor, it is also known as alpha1–proteinase inhibitor (A1PI) or alpha1-antiproteinase (A1AP) because it inhibits various proteases (not just trypsin). In older biomedical literature it was sometimes called serum trypsin inhibitor (STI, dated terminology), because its capability as a trypsin inhibitor was a salient feature of its early study. As a type of enzyme inhibitor, it protects tissues from enzymes of inflammatory cells, especially neutrophil elastase, and has a reference range in blood of 0.9–2.3 g/L (in the US the reference range is expressed as mg/dL or micromoles), but the concentration can rise manyfold upon acute inflammation. When the blood contains inadequate amounts of A1AT or functionally defective A1AT (such as in alpha-1 antitrypsin deficiency), neutrophil elastase is excessi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emphysema
Emphysema, or pulmonary emphysema, is a lower respiratory tract disease, characterised by air-filled spaces ( pneumatoses) in the lungs, that can vary in size and may be very large. The spaces are caused by the breakdown of the walls of the alveoli and they replace the spongy lung parenchyma. This reduces the total alveolar surface available for gas exchange leading to a reduction in oxygen supply for the blood. Emphysema usually affects the middle aged or older population because it takes time to develop with the effects of tobacco smoking, and other risk factors. Alpha-1 antitrypsin deficiency is a genetic risk factor that may lead to the condition presenting earlier. When associated with significant airflow limitation, emphysema is a major subtype of chronic obstructive pulmonary disease (COPD), a progressive lung disease characterized by long-term breathing problems and poor airflow. Without COPD, the finding of emphysema on a CT lung scan still confers a higher mortality r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nationalencyklopedin
''Nationalencyklopedin'' (; "The National Encyclopedia" in English), abbreviated NE, is a comprehensive contemporary Swedish-language encyclopedia, initiated by a favourable loan from the Government of Sweden of 17 million Swedish kronor in 1980, which was repaid by December 1990. The printed version consists of 20 volumes with 172,000 articles; the Internet version comprises 260,000 articles (as of June 2005). History The project was born in 1980, when a government committee suggested that negotiations be initiated with various publishers. This stage was finished in August 1985, when in Höganäs became the publisher responsible for the project. The project specifications were for a modern reference work based on a scientific paradigm incorporating gender and environmental issues. Pre-orders for the work were unprecedented; before the first volume was published in December 1989, 54,000 customers had ordered the encyclopedia. The last volume came out in 1996, with three suppl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Swedish Academy Of Sciences
The Royal Swedish Academy of Sciences ( sv, Kungliga Vetenskapsakademien) is one of the Swedish Royal Academies, royal academies of Sweden. Founded on 2 June 1739, it is an independent, non-governmental scientific organization that takes special responsibility for promoting natural sciences and mathematics and strengthening their influence in society, whilst endeavouring to promote the exchange of ideas between various disciplines. The goals of the academy are: * to be a forum where researchers meet across subject boundaries, * to offer a unique environment for research, * to provide support to younger researchers, * to reward outstanding research efforts, * to communicate internationally among scientists, * to advance the case for science within society and to influence research policy priorities * to stimulate interest in mathematics and science in school, and * to disseminate and popularize scientific information in various forms. Every year, the academy awards the Nobel Priz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Association For Clinical Chemistry
AACC (formerly known as the American Association for Clinical Chemistry) is a global scientific society dedicated to clinical laboratory science and its application to healthcare. AACC's current president is Carmen Wiley, PhD, and the association headquarters are located in Washington, D.C. (United States). AACC Members AACC's approximately 8,000 members come from all areas of lab medicine—clinical and research laboratories, diagnostic companies, government agencies, original equipment manufacturers, and more. Collectively they develop and run lab tests and lab instruments used throughout healthcare. They also manage labs, conduct research involving biomarkers, and promote accurate diagnostic testing. AACC represents the diverse interests of a global lab community: its members come from 110 countries and hold the spectrum of lab-related professional degrees, certifications, and credentials. AACC Annual Scientific Meeting AACC holds several scientific conferences each year, the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1919 Births
Events January * January 1 ** The Czechoslovak Legions occupy much of the self-proclaimed "free city" of Pressburg (now Bratislava), enforcing its incorporation into the new republic of Czechoslovakia. ** HMY ''Iolaire'' sinks off the coast of the Hebrides; 201 people, mostly servicemen returning home to Lewis and Harris, are killed. * January 2– 22 – Russian Civil War: The Red Army's Caspian-Caucasian Front begins the Northern Caucasus Operation against the White Army, but fails to make progress. * January 3 – The Faisal–Weizmann Agreement is signed by Emir Faisal (representing the Arab Kingdom of Hejaz) and Zionist leader Chaim Weizmann, for Arab–Jewish cooperation in the development of a Jewish homeland in Palestine, and an Arab nation in a large part of the Middle East. * January 5 – In Germany: ** Spartacist uprising in Berlin: The Marxist Spartacus League, with the newly formed Communist Party of Germany and the Independent Social De ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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