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C. David Allis
Charles David Allis (March 22, 1951 – January 8, 2023) was an American molecular biologist, and the Joy and Jack Fishman Professor at the Rockefeller University. He was also the Head of the Laboratory of Chromatin Biology and Epigenetics, and a professor at the Tri-Institutional MD–PhD Program (the other two institutions being the Memorial Sloan Kettering Cancer Center and Weill Cornell Medicine). Early life and education Allis was born and raised in Cincinnati, Ohio. His father was a city planner and his mother an elementary school teacher. He entered the University of Cincinnati in 1969, majoring in biology. He had his first experience of basic research in his senior (or fourth) year of BSc. The experience attracted him to research, and he went to Indiana University for graduate studies. He graduated with an MSc in 1975 and a PhD three years later, under the supervision of Anthony Mahowald. Career Allis undertook a postdoctoral fellowship in the University of Roche ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Cincinnati Enquirer
''The Cincinnati Enquirer'' is a morning daily newspaper published by Gannett in Cincinnati, Ohio, United States. First published in 1841, the ''Enquirer'' is the last remaining daily newspaper in Greater Cincinnati and Northern Kentucky, although the daily ''Journal-News'' competes with the ''Enquirer'' in the northern suburbs. The ''Enquirer'' has the highest circulation of any print publication in the Cincinnati metropolitan area. A daily local edition for Northern Kentucky is published as ''The Kentucky Enquirer''. ''The Enquirer'' won the 2018 Pulitzer Prize for local reporting for its project titled "Seven Days of Heroin". In addition to the ''Cincinnati Enquirer'' and ''Kentucky Enquirer'', Gannett publishes a variety of print and electronic periodicals in the Cincinnati area, including 16 ''Community Press'' weekly newspapers, 10 ''Community Recorder'' weekly newspapers, and ''OurTown'' magazine. The ''Enquirer'' is available online at the ' website. Content The ''Enq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthony Mahowald
Anthony Mahowald (born November 24, 1932) is a molecular genetics and cellular biologist who served as the department chair of the molecular genetics and cellular biology department at the University of Chicago. His lab focused on the Drosophila melanogaster, which is often referred to as fruit fly, specifically focusing on controlling the genetic aspect of major developmental events. His major research breakthroughs included the study of the stem cell niche, endocycles, and various types of actin. Personal life Anthony Mahowald is married and has three children. Educational career Anthony Mahowald was born in Albany, Minnesota, on November 24, 1932. Mahowald received a bachelor's degree from Spring Hill College in Mobile, Alabama. Following his undergraduate studies, Mahowald earned his Ph.D. from Johns Hopkins University in 1962. At Johns Hopkins, Mahowald studied the structure of pole cells and polar granules in Drosophila melanogaster. Both his undergraduate and doctora ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK or MSKCC) is a cancer treatment and research institution in the borough of Manhattan in New York City, founded in 1884 as the New York Cancer Hospital. MSKCC is one of 52 National Cancer Institute–designated Comprehensive Cancer Centers. Its main campus is located at 1275 York Avenue, between 67th and 68th streets, in Manhattan. According to U.S. News & World Report 2021-2022 Best Hospitals, Memorial Sloan Kettering Cancer Center (MSK) has been ranked as the number two hospital for cancer care in the nation. History New York Cancer Hospital (1884–1934) Memorial Hospital was founded on the Upper West Side of Manhattan in 1884 as the New York Cancer Hospital by a group that included John Jacob Astor III and his wife Charlotte. The hospital appointed as an attending surgeon William B. Coley, who pioneered an early form of immunotherapy to eradicate tumors. Rose Hawthorne, daughter of author Nathaniel Hawthorne, trained there in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tri-Institutional MD–PhD Program
The Tri-Institutional MD-PhD Program is an MD-PhD program based in New York City that was formed by combining earlier MD-PhD programs that had their inceptions in 1972. The current version of the program, which is operated by Weill Cornell Medicine, The Rockefeller University, and the Memorial Sloan-Kettering Cancer Center's Sloan Kettering Institute, was created in 1991. Located in the Upper East Side of New York City, the program is currently directed by Dr. Katharine C. Hsu of the Memorial Sloan-Kettering Cancer Center. Profile Students who complete the program are awarded an M.D. from Weill Cornell Medical College and a Ph.D. from either Weill Cornell Medicine Graduate School of Medical Sciences, The Rockefeller University, or the Gerstner Sloan Kettering Graduate School of Biomedical Sciences. In 2019, the program processed over 500 applications for 18 spots. These positions are funded by the National Institutes of Health Medical Scientist Training Program (MSTP) for the fu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chromatin
Chromatin is a complex of DNA and protein found in eukaryotic cells. The primary function is to package long DNA molecules into more compact, denser structures. This prevents the strands from becoming tangled and also plays important roles in reinforcing the DNA during cell division, preventing DNA damage, and regulating gene expression and DNA replication. During mitosis and meiosis, chromatin facilitates proper segregation of the chromosomes in anaphase; the characteristic shapes of chromosomes visible during this stage are the result of DNA being coiled into highly condensed chromatin. The primary protein components of chromatin are histones. An octamer of two sets of four histone cores (Histone H2A, Histone H2B, Histone H3, and Histone H4) bind to DNA and function as "anchors" around which the strands are wound.Maeshima, K., Ide, S., & Babokhov, M. (2019). Dynamic chromatin organization without the 30-nm fiber. ''Current opinion in cell biology, 58,'' 95–104. https://doi.o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jack Fishman
Jack Fishman (September 30, 1930 – December 7, 2013), born Jacob Fiszman, was a Jewish-American pharmaceutical researcher from Kraków, Poland. In 1961, along with Mozes J. Lewenstein, he developed the medication naloxone, which can reverse an opioid overdose, and the Centers for Disease Control and Prevention has described as a "a life-saving medication that can reverse an overdose from opioids—including heroin, fentanyl, and prescription opioid medications." Personal life He fled the Nazi occupation of Poland with his parents when he was eight and spent much of his youth in Shanghai, where he attended a Jewish school. He emigrated to the United States at age 18. He was married four times, with three marriages ending in divorce. He married Joy Stampler, whose son from a previous relationship died of an opioid overdose in 2003. Stampler Fishman had no idea that naloxone existed or that carrying it would have saved her son, let alone that her current husband had helped in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albany Medical Center Prize
The Albany Medical Center Prize in Medicine and Biomedical Research is the United States' second highest value prize in medicine and biomedical research, awarded by the Albany Medical Center. Among prizes for medicine worldwide, the Albany Medical Center Prize is the fourth most lucrative (after the $3 million Breakthrough Prize in Life Sciences, the $1.2 million Nobel Prize in Medicine and the $1 million Shaw Prize in life science and medicine). Awarded annually, the $500,000 prize is bestowed to any physician or scientist, or group, whose work has led to significant advances in the fields of health care and scientific research with demonstrated translational benefits applied to improved patient care. The prize is a legacy to its founder, the late Morris "Marty" Silverman. At the inaugural awards ceremony in Albany, NY in March 2001, Silverman started a tradition that will be carried on for one hundred years, the duration of the Prize. Silverman's promise was to light one candle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Lasker Award For Basic Medical Research
The Albert Lasker Award for Basic Medical Research is one of the prizes awarded by the Lasker Foundation for a fundamental discovery that opens up a new area of biomedical science. The award frequently precedes a Nobel Prize in Medicine; almost 50% of the winners have gone on to win one. List of Albert Lasker Award for Basic Medical Research recipients {, , Valign="top", {, class="wikitable" ! Year !! Recipient , - , Rowspan="3", 2022 , , Richard O. Hynes , - , , Erkki Ruoslahti , - , , Timothy A. Springer , - , Rowspan="3", 2021 , , Karl Deisseroth , - , , Peter Hegemann , - , , Dieter Oesterhelt , - , Rowspan="1", 2020 , , not awarded , - , Rowspan="2", 2019 , , Max Dale Cooper , - , , Jacques Miller , - , Rowspan="2", 2018 , , C. David Allis , - , , Michael Grunstein , - , Rowspan="1", 2017 , , Michael N. Hall , - , Rowspan="3", 2016 , , William Kaelin, Jr. , - , , Peter J. Ratcliffe , - , , Gregg L. Semenza , - , R ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gruber Prize In Genetics
The Gruber Prize in Genetics, established in 2001, is one of three international awards worth US$500,000 made by the Gruber Foundation, a non-profit organization based at Yale University in New Haven, Connecticut. The Genetics Prize honors leading scientists for distinguished contributions in any realm of genetics research. The Foundation’s other international prizes are in Cosmology, Neuroscience, Justice, and Women’s Rights. Recipients *2022 Ruth Lehmann (Whitehead Institute and MIT), James Priess (Fred Hutchinson Cancer Research Center), and Geraldine Seydoux (Johns Hopkins University School of Medicine). *2021 Stuart H. Orkin (Harvard Medical School, Howard Hughes Medical Institute) *2020 Bonnie Bassler (Princeton University, Howard Hughes Medical Institute) *2019 Bert Vogelstein (Johns Hopkins Hospital, Howard Hughes Medical Institute) *2018 Joanne Chory (Salk Institute for Biological Studies), and Elliot Meyerowitz (Caltech) *2017 Stephen J. Elledge, Harvard Medical S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Breakthrough Prize In Life Sciences
The Breakthrough Prize in Life Sciences is a scientific award, funded by internet entrepreneurs Mark Zuckerberg and Priscilla Chan of Facebook; Sergey Brin of Google; entrepreneur and venture capitalist Yuri Milner; and Anne Wojcicki, one of the founders of the genetics company 23andMe. The award of $3 million, the largest award in the sciences,The Economist. "Take it, Alfred" https://www.economist.com/blogs/babbage/2013/02/science-prizes is given to researchers who have made discoveries that extend human life. The Prize is awarded annually, beginning in 2013, with six awards given in each subsequent year. Winners are expected to give public lectures and form the committee to decide future winners. The ceremony takes place in the San Francisco Bay Area, with the symposiums alternating between University of California, Berkeley, University of California, San Francisco, and Stanford University. Laureates See also * Breakthrough Prize in Mathematics * Fundamental Physics Prize ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Grand Prix Charles-Leopold Mayer
The Grand Prix Charles-Léopold Mayer (Charles-Léopold Mayer Prize) is awarded annually by the Académie des Sciences (French Academy of Sciences) de l'Institut de France (the French Institute) to researchers who have performed outstanding work in the biological sciences; especially in the areas of cell or molecular biology. Citizens or residents of any nation are eligible for the prize, but it is never awarded to individuals of the same nation two years in a row, nor is the prize ever presented to scholars who are more than 65 years of age. Between the first presentation of the award in 1961 and the year 2009, there have been more than 60 laureates, eleven of whom subsequently received the Nobel Prize in medicine, physiology, or chemistry. The prize is named after French biochemist Charles Léopold Mayer. List of Recipients of the Grand Prix Charles-Léopold Mayer Source Académie des sciences *2019 - Silvia Arber *2018 - Eric Gilson *2016 - Claude Desplan *2015 - François Sc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
