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Bryan Clarke
Bryan Campbell Clarke (24 June 1932 – 27 February 2014) was a British Professor of genetics, latterly emeritus at the University of Nottingham. Clarke is particularly noted for his work on apostatic selection (which is a term he coined in 1962) and other forms of frequency-dependent selection, and work on polymorphism in snails, much of it done during the 1960s. Later, he studied molecular evolution. He made the case for natural selection as an important factor in the maintenance of molecular variation, and in driving evolutionary changes in molecules through time. In doing so, he questioned the over-riding importance of random genetic drift advocated by King, Jukes, and Kimura. With Professor James J Murray Jnr (University of Virginia), he carried out an extensive series of studies on speciation in land snails of the genus '' Partula'' inhabiting the volcanic islands of the Eastern Pacific. These studies helped illuminate the genetic changes that take place during the o ...
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Nottingham
Nottingham ( , locally ) is a city and unitary authority area in Nottinghamshire, East Midlands, England. It is located north-west of London, south-east of Sheffield and north-east of Birmingham. Nottingham has links to the legend of Robin Hood and to the lace-making, bicycle and tobacco industries. The city is also the county town of Nottinghamshire and the settlement was granted its city charter in 1897, as part of Queen Victoria's Diamond Jubilee celebrations. Nottingham is a tourist destination; in 2018, the city received the second-highest number of overnight visitors in the Midlands and the highest number in the East Midlands. In 2020, Nottingham had an estimated population of 330,000. The wider conurbation, which includes many of the city's suburbs, has a population of 768,638. It is the largest urban area in the East Midlands and the second-largest in the Midlands. Its Functional Urban Area, the largest in the East Midlands, has a population of 919,484. The popula ...
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Molecular Evolution
Molecular evolution is the process of change in the sequence composition of cellular molecules such as DNA, RNA, and proteins across generations. The field of molecular evolution uses principles of evolutionary biology and population genetics to explain patterns in these changes. Major topics in molecular evolution concern the rates and impacts of single nucleotide changes, neutral evolution vs. natural selection, origins of new genes, the genetic nature of complex traits, the genetic basis of speciation, evolution of development, and ways that evolutionary forces influence genomic and phenotypic changes. History The history of molecular evolution starts in the early 20th century with comparative biochemistry, and the use of "fingerprinting" methods such as immune assays, gel electrophoresis and paper chromatography in the 1950s to explore homologous proteins. The field of molecular evolution came into its own in the 1960s and 1970s, following the rise of molecular ...
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Frozen Ark
The Frozen Ark is a charitable frozen zoo project created jointly by the Zoological Society of London, the Natural History Museum and University of Nottingham. The project aims to preserve the DNA and living cells of endangered species to retain the genetic knowledge for the future. The Frozen Ark collects and stores samples taken from animals in zoos and those threatened with extinction in the wild. Its current director is Michael W. Bruford (Cardiff University). The Frozen Ark was a finalist for the Saatchi & Saatchi Award for World Changing Ideas in 2006. The project was founded by Ann Clarke, her husband Bryan Clarke and Dame Anne McLaren. Since Bryan Clarke′s death in 2014, the Frozen Ark′s interim director has been Mike Bruford Michael William Bruford (born 6 June 1963) is a Welsh molecular ecologist, conservation biologist and currently professor at Cardiff University's School of Biosciences. His area of research spans from animal wildlife genetics to the mana ...
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Anne McLaren
Dame Anne Laura Dorinthea McLaren, (26 April 1927 – 7 July 2007) was a British scientist who was a leading figure in developmental biology. Her work helped lead to human in vitro fertilisation (IVF),''The Telegraph'' obituary for Prof. Dame Anne McLaren
9 July 2007
and she received many honours for her contributions to science, including election as fellow of the .


Early life

McLaren was the daughter of Sir

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Population Genetics
Population genetics is a subfield of genetics that deals with genetic differences within and between populations, and is a part of evolutionary biology. Studies in this branch of biology examine such phenomena as Adaptation (biology), adaptation, speciation, and population stratification, population structure. Population genetics was a vital ingredient in the emergence of the Modern synthesis (20th century), modern evolutionary synthesis. Its primary founders were Sewall Wright, J. B. S. Haldane and Ronald Fisher, who also laid the foundations for the related discipline of quantitative genetics. Traditionally a highly mathematical discipline, modern population genetics encompasses theoretical, laboratory, and field work. Population genetic models are used both for statistical inference from DNA sequence data and for proof/disproof of concept. What sets population genetics apart from newer, more phenotypic approaches to modelling evolution, such as evolutionary game theory and evo ...
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Reader (academic Rank)
The title of reader in the United Kingdom and some universities in the Commonwealth of Nations, for example India, Australia and New Zealand, denotes an appointment for a senior academic with a distinguished international reputation in research or scholarship. In the traditional hierarchy of British and other Commonwealth universities, reader (and principal lecturer in the new universities) are academic ranks above senior lecturer and below professor, recognising a distinguished record of original research. Reader is similar to a professor without a chair, similar to the distinction between ''professor extraordinarius'' and ''professor ordinarius'' at some European universities, professor and chaired professor in Hong Kong and "professor name" (or associate professor) and chaired professor in Ireland. Readers and professors in the UK would correspond to full professors in the United States.Graham WebbMaking the most of appraisal: career and professional development planning for ...
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Lecturer
Lecturer is an academic rank within many universities, though the meaning of the term varies somewhat from country to country. It generally denotes an academic expert who is hired to teach on a full- or part-time basis. They may also conduct research. Comparison The table presents a broad overview of the traditional main systems, but there are universities which use a combination of those systems or other titles. Note that some universities in Commonwealth countries have adopted the American system in place of the Commonwealth system. Uses around the world Australia In Australia, the term lecturer may be used informally to refer to anyone who conducts lectures at a university or elsewhere, but formally refers to a specific academic rank. The academic ranks in Australia are similar to those in the UK, with the rank of associate professor roughly equivalent to reader in UK universities. The academic levels in Australia are (in ascending academic level): (A) associate lecture ...
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Cepaea
''Cepaea'' is a genus of medium-sized air-breathing land snails, terrestrial pulmonate gastropod mollusks in the family Helicidae. The shells of species within this genus are often brightly colored and patterned with stripes. The two species from this genus, the common and widespread ''C. nemoralis'' and ''C. hortensis'', have been model species for early studies of genetics and natural selection. They occur in Europe, although introduced populations occur elsewhere in the world. Like many Helicidae, this genus of snails create and use love darts. Species For a long time, four species were classified in the genus ''Cepaea''. However, molecular phylogenetic studies suggested that the latter two should be placed in the unrelated genera ''Macularia'' and ''Caucasotachea'': * ''Cepaea hortensis'' (O. F. Müller, 1774) – white-lipped snail or garden banded snail * ''Cepaea nemoralis The grove snail, brown-lipped snail or Lemon snail (''Cepaea nemoralis'') is a species of a ...
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Polymorphism (biology)
In biology, polymorphism is the occurrence of two or more clearly different morphs or forms, also referred to as alternative ''phenotypes'', in the population of a species. To be classified as such, morphs must occupy the same habitat at the same time and belong to a panmictic population (one with random mating). Ford E.B. 1965. ''Genetic polymorphism''. Faber & Faber, London. Put simply, polymorphism is when there are two or more possibilities of a trait on a gene. For example, there is more than one possible trait in terms of a jaguar's skin colouring; they can be light morph or dark morph. Due to having more than one possible variation for this gene, it is termed 'polymorphism'. However, if the jaguar has only one possible trait for that gene, it would be termed "monomorphic". For example, if there was only one possible skin colour that a jaguar could have, it would be termed monomorphic. The term polyphenism can be used to clarify that the different forms arise from the ...
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Doctor Of Philosophy
A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is an earned research degree, those studying for a PhD are required to produce original research that expands the boundaries of knowledge, normally in the form of a dissertation, and defend their work before a panel of other experts in the field. The completion of a PhD is often a requirement for employment as a university professor, researcher, or scientist in many fields. Individuals who have earned a Doctor of Philosophy degree may, in many jurisdictions, use the title ''Doctor'' (often abbreviated "Dr" or "Dr.") with their name, although the proper etiquette associated with this usage may also be subject to the professional ethics of their own scholarly field, culture, or society. Those who teach at universities or work in academic, edu ...
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Bachelor Of Arts
Bachelor of arts (BA or AB; from the Latin ', ', or ') is a bachelor's degree awarded for an undergraduate program in the arts, or, in some cases, other disciplines. A Bachelor of Arts degree course is generally completed in three or four years, depending on the country and institution. * Degree attainment typically takes four years in Afghanistan, Armenia, Azerbaijan, Bangladesh, Brazil, Brunei, China, Egypt, Ghana, Greece, Georgia, Hong Kong, Indonesia, Iran, Iraq, Ireland, Japan, Kazakhstan, Kenya, Kuwait, Latvia, Lebanon, Lithuania, Mexico, Malaysia, Mongolia, Myanmar, Nepal, Netherlands, Nigeria, Pakistan, the Philippines, Qatar, Russia, Saudi Arabia, Scotland, Serbia, South Korea, Spain, Sri Lanka, Taiwan, Thailand, Turkey, Ukraine, the United States and Zambia. * Degree attainment typically takes three years in Albania, Australia, Bosnia and Herzegovina, the Caribbean, Iceland, India, Israel, Italy, New Zealand, Norway, South Africa, Switzerland, the Canadian province o ...
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Magdalen College, Oxford
Magdalen College (, ) is a constituent college of the University of Oxford. It was founded in 1458 by William of Waynflete. Today, it is the fourth wealthiest college, with a financial endowment of £332.1 million as of 2019 and one of the strongest academically, setting the record for the highest Norrington Score in 2010 and topping the table twice since then. It is home to several of the university's distinguished chairs, including the Agnelli-Serena Professorship, the Sherardian Professorship, and the four Waynflete Professorships. The large, square Magdalen Tower is an Oxford landmark, and it is a tradition, dating to the days of Henry VII, that the college choir sings from the top of it at 6 a.m. on May Morning. The college stands next to the River Cherwell and the University of Oxford Botanic Garden. Within its grounds are a deer park and Addison's Walk. History Foundation Magdalen College was founded in 1458 by William of Waynflete, Bishop of Winche ...
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