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Brendan Crabb
Brendan Scott Crabb FASM (born 13 September 1966) is an Australian microbiologist, research scientist and director and chief executive officer of the Burnet Institute, based in Melbourne, Victoria, Australia. Background and early career Educated in Papua New Guinea and Australia, Crabb received a Bachelor of Science (Honours) from the University of Melbourne in the Department of Microbiology. In 1992, he completed his PhD in virology with Michael J. Studdert at the School of Veterinary Science also at the University of Melbourne. His PhD project, which explored proteins of equine herpes, led to a diagnostic test which could distinguish horses infected by the lethal equine herpes virus-1 and the less damaging equine herpes virus-4. He then completed a postdoctoral fellowship in the laboratory of Alan Cowman before starting his independent laboratory at the University of Melbourne. Scientific career Research focus Crabb's main research focus is on the identification of new tar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunology
Immunology is a branch of medicineImmunology for Medical Students, Roderick Nairn, Matthew Helbert, Mosby, 2007 and biology that covers the medical study of immune systems in humans, animals, plants and sapient species. In such we can see there is a difference of human immunology and comparative immunology in veterinary medicine and animal biosciences. Immunology measures, uses charts and differentiate in context in medicine the studies of immunity on cell and molecular level, and the immune system as part of the physiological level as its functioning is of major importance. In the different states of both health, occurring symptoms and diseases; the functioning of the immune system and immunological responses such as autoimmune diseases, allergic hypersensitivities, or in some cases malfunctioning of immune system as for example in immunological disorders or in immune deficiency, and the specific transplant rejection) Immunology has applications in numerous disciplines of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cytosol
The cytosol, also known as cytoplasmic matrix or groundplasm, is one of the liquids found inside cells (intracellular fluid (ICF)). It is separated into compartments by membranes. For example, the mitochondrial matrix separates the mitochondrion into many compartments. In the eukaryotic cell, the cytosol is surrounded by the cell membrane and is part of the cytoplasm, which also comprises the mitochondria, plastids, and other organelles (but not their internal fluids and structures); the cell nucleus is separate. The cytosol is thus a liquid matrix around the organelles. In prokaryotes, most of the chemical reactions of metabolism take place in the cytosol, while a few take place in membranes or in the periplasmic space. In eukaryotes, while many metabolic pathways still occur in the cytosol, others take place within organelles. The cytosol is a complex mixture of substances dissolved in water. Although water forms the large majority of the cytosol, its structure and prope ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myanmar
Myanmar, ; UK pronunciations: US pronunciations incl. . Note: Wikipedia's IPA conventions require indicating /r/ even in British English although only some British English speakers pronounce r at the end of syllables. As John C. Wells, John Wells explains, the English spellings of both Myanmar and Burma assume a non-rhotic variety of English, in which the letter r before a consonant or finally serves merely to indicate a long vowel: [ˈmjænmɑː, ˈbɜːmə]. So the pronunciation of the last syllable of Myanmar as [mɑːr] or of Burma as [bɜːrmə] by some speakers in the UK and most speakers in North America is in fact a spelling pronunciation based on a misunderstanding of non-rhotic spelling conventions. The final ''r'' in ''Myanmar'' was not intended for pronunciation and is there to ensure that the final a is pronounced with the broad a, broad ''ah'' () in "father". If the Burmese name my, မြန်မာ, label=none were spelled "Myanma" in English, this would b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Asia Pacific
Asia-Pacific (APAC) is the part of the world near the western Pacific Ocean. The Asia-Pacific region varies in area depending on context, but it generally includes East Asia, Russian Far East, South Asia, Southeast Asia, Australia and Pacific Islands. Definition The term may include countries in North America and South America that are on the coast of the Eastern Pacific Ocean; the Asia-Pacific Economic Cooperation, for example, includes Canada, Chile, Mexico, Peru, and the United States. Alternatively, the term sometimes comprises all of Asia and Australasia as well as Pacific island nations (Asia-Pacific and Australian continent)—for example, when dividing the world into large regions for commercial purposes (e.g., into APAC, EMEA, LATAM, and NA). Central Asia and Western Asia are almost never included. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Development
International development or global development is a broad concept denoting the idea that societies and countries have differing levels of economic or human development on an international scale. It is the basis for international classifications such as developed country, developing country and least developed country, and for a field of practice and research that in various ways engages with international development processes. There are, however, many schools of thought and conventions regarding which are the exact features constituting the "development" of a country. Historically, development was largely synonymous with economic development, and especially its convenient but flawed quantification (see parable of the broken window) through readily gathered (for developed countries) or estimated monetary proxies (estimated for severely undeveloped or isolationist countries) such as gross domestic product (GDP), often viewed alongside actuarial measures such as life expectancy. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stunted Growth
Stunted growth is a reduced growth rate in human development. It is a primary manifestation of malnutrition (or more precisely undernutrition) and recurrent infections, such as diarrhea and helminthiasis, in early childhood and even before birth, due to malnutrition during fetal development brought on by a malnourished mother. The definition of stunting according to the World Health Organization (WHO) is for the "height for age" value to be less than two standard deviations of the WHO Child Growth Standards median. As of 2012 an estimated 162 million children under 5 years of age, or 25%, were stunted. More than 90% of the world's stunted children live in Africa and Asia, where respectively 36% and 56% of children are affected. Once established, stunting and its effects typically become permanent. Stunted children may never regain the height lost as a result of stunting, and most children will never gain the corresponding body weight. Living in an environment where many people de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Low Birth Weight
Low birth weight (LBW) is defined by the World Health Organization as a birth weight of an infant of or less, regardless of gestational age. Infants born with LBW have added health risks which require close management, often in a neonatal intensive care unit (NICU). They are also at increased risk for long-term health conditions which require follow-up over time. Classification Birth weight may be classified as: * High birth weight (macrosomia): greater than * Normal weight (term delivery): * Low birth weight: less than ** Very low birth weight: less than ** Extremely low birth weight: less than Causes LBW is either caused by preterm birth (that is, a low gestational age at birth, commonly defined as younger than 37 weeks of gestation) or the infant being small for gestational age (that is, a slow prenatal growth rate), or a combination of both. In general, risk factors in the mother that may contribute to low birth weight include young ages, multiple pregnancies, previous ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
East New Britain
East New Britain is a province of Papua New Guinea, consisting of the north-eastern part of the island of New Britain and the Duke of York Islands. The capital of the province is Kokopo, not far from the old capital of Rabaul, which was largely destroyed in a volcanic eruption in 1994. East New Britain covers a total land area of , and the province's population was reported as 220,133 in the 2000 census, rising to 328,369 in the 2011 count. Provincial coastal waters extend over an area of . The province's only land border is with West New Britain Province to the west, and it also shares a maritime border with New Ireland Province to the east. East New Britain has a dual economy: a cash economy operates side by side with the subsistence-farming sector. The main crops produced for export are cocoa and copra. Tourism continues to be an increasingly important sector of the provincial economy. Languages There are sixteen Austronesian languages spoken in the province, of which Kuanua, s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
South Australian Health And Medical Research Institute
The South Australian Health and Medical Research Institute (SAHMRI) is an independent health and medical research institute in Adelaide, South Australia. The institute is housed in a purpose-built eponymous building with its iconic " cheese-grater" design created by architects Woods Bagot, located in South Australia's health and biomedical precinct on North Terrace, just east of the Royal Adelaide Hospital. The institute is composed of approximately 700 researchers, many of whom have links to, and work collaboratively with, other research institutes in Australia and overseas. The institute was officially incorporated in December 2009, and opened in its current location on 29 November 2013. A second building (SAHMRI 2) is under construction as of August 2022, and will house the Australian Bragg Centre for Proton Therapy & Research after its completion, scheduled in late 2023. Establishment In 2007 the South Australian Government commissioned the ''Review of Health and Medica ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ian Gust
Ian David Gust Officer of the Order of Australia, AO, Fellow of the Royal College of Pathologists of Australasia, FRCPA, Fellow of the Royal Australasian College of Physicians, FRACP, MASM, FT (born 15 January 1941) is an Australians, Australian medical researcher, Virology, virologist, and former science administrator. Gust's area of work is in the development of drugs and vaccines against viral diseases and he is best known for the development of vaccines against the Hepatitis A virus. He currently serves as a non–executive company director and consultant. Gust is the son of Itzhak Gust, a prominent Jewish socialist who migrated to Australia from Poland, via Palestine, in the 1930s. His sister is the writer Amirah Inglis. Career After an initial Residency (medicine), residency at The Alfred Hospital, Gust was appointed as a pathology registrar at the Fairfield Infectious Diseases Hospital, Melbourne, Victoria, Melbourne, Australia; then spending two years in the United Kingd ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasmodium Falciparum
''Plasmodium falciparum'' is a Unicellular organism, unicellular protozoan parasite of humans, and the deadliest species of ''Plasmodium'' that causes malaria in humans. The parasite is transmitted through the bite of a female ''Anopheles'' mosquito and causes the disease's most dangerous form, falciparum malaria. It is responsible for around 50% of all malaria cases. ''P. falciparum'' is therefore regarded as the deadliest parasite in humans. It is also associated with the development of blood cancer (Burkitt's lymphoma) and is classified as a List of IARC Group 2A carcinogens, Group 2A (probable) carcinogen. The species originated from the malarial parasite ''Laverania'' found in gorillas, around 10,000 years ago. Alphonse Laveran was the first to identify the parasite in 1880, and named it ''Oscillaria malariae''. Ronald Ross discovered its transmission by mosquito in 1897. Giovanni Battista Grassi elucidated the complete transmission from a female Anopheles, anopheline mosquit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Knockout
A gene knockout (abbreviation: KO) is a genetic technique in which one of an organism's genes is made inoperative ("knocked out" of the organism). However, KO can also refer to the gene that is knocked out or the organism that carries the gene knockout. Knockout organisms or simply knockouts are used to study gene function, usually by investigating the effect of gene loss. Researchers draw inferences from the difference between the knockout organism and normal individuals. The KO technique is essentially the opposite of a gene knock-in. Knocking out two genes simultaneously in an organism is known as a double knockout (DKO). Similarly the terms triple knockout (TKO) and quadruple knockouts (QKO) are used to describe three or four knocked out genes, respectively. However, one needs to distinguish between heterozygous and homozygous KOs. In the former, only one of two gene copies (alleles) is knocked out, in the latter both are knocked out. Methods Knockouts are accomplished throu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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