Ian Gust
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Ian David Gust AO, FRCPA,
FRACP Fellow of the Royal Australasian College of Physicians, abbreviated as the post-nominal initials FRACP, is a recognition of the completion of the prescribed postgraduate specialist training programme in internal adult or internal paediatric medicin ...
, MASM, FT (born 15 January 1941) is an Australian
medical researcher Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientif ...
,
virologist Virology is the scientific study of biological viruses. It is a subfield of microbiology that focuses on their detection, structure, classification and evolution, their methods of infection and exploitation of host cells for reproduction, their ...
, and former science administrator. Gust's area of work is in the development of drugs and vaccines against viral diseases and he is best known for the development of vaccines against the Hepatitis A virus. He currently serves as a non–executive company director and consultant. Gust is the son of Itzhak Gust, a prominent Jewish socialist who migrated to Australia from Poland, via Palestine, in the 1930s. His sister is the writer
Amirah Inglis Amirah Inglis (née Gutstadt, then Gust, then Turner, finally Inglis) (7 December 1926 – 2 May 2015) was an Australian communist activist and writer. Biography Inglis was born Amirah Gutstadt in 1926 in Brussels, Belgium, to Itzhak (also kn ...
.


Career

After an initial
residency Residency may refer to: * Domicile (law), the act of establishing or maintaining a residence in a given place ** Permanent residency, indefinite residence within a country despite not having citizenship * Residency (medicine), a stage of postgrad ...
at
The Alfred Hospital The Alfred Hospital, also known as The Alfred or Alfred Hospital, is a leading tertiary teaching hospital in Melbourne, Victoria. It is the second oldest hospital in Victoria, and the oldest Melbourne hospital still operating on its original site ...
, Gust was appointed as a pathology registrar at the
Fairfield Infectious Diseases Hospital Fairfield Infectious Diseases Hospital, originally known as Queens Memorial Infectious Diseases Hospital, operated from 1904 to its closure in 1996. Perched high on the banks of the Yarra River at Yarra Bend in the inner Melbourne suburb of Fai ...
, Melbourne, Australia; then spending two years in the United Kingdom at the London School of Hygiene and Tropical Medicine and the WHO Regional Virus Laboratory in Glasgow. Gust returned to Fairfield in 1970 and was appointed a medical virologist at the Infectious Diseases Hospital, a position he held for over twenty years. During this period, Fairfield gained a worldwide reputation for virology education, research and treatment. The laboratory was the first to isolate hepatitis A virus and one of the first strains of respiratory syncytial virus (the A2 strain, now a reference A group virus). In 1985, Gust was appointed as the inaugural director of the Macfarlane Burnet Centre for Medical Research, Fairfield Hospital, now commonly known as the
Burnet Institute The Burnet Institute is an Australian medical institute that combines medical research in the laboratory and the field, with public health action to address major health issues affecting disadvantaged communities in Australia, and international ...
, holding this position until 1991. Between 1991 and 2008, Gust served as director of research and development for the Commonwealth Serum Laboratories, now listed as
CSL Limited CSL Limited is an Australian multinational specialty biotechnology company that researches, develops, manufactures, and markets products to treat and prevent serious human medical conditions. CSL's product areas include blood plasma derivative ...
, where he was closely involved in the company's successful expansion in Australia and internationally. Since his retirement, he has been a Professorial Fellow in the Department of Microbiology and Immunology in the University of Melbourne, and as a consultant to the Bill and Melinda Gates Foundation; to UNICEF, the World Bank and the World Health Organization. A non–executive director of biotechnology company, Biota Holdings Limited, since 2001, Gust is also a director of Promics Pty Ltd. Gust served variously as a member of WHO expert committees on viral hepatitis (1974, 1979, 1982), biological standardisation (1992), and virus diseases (1975, 1985–1991). He has been a Director of the National Hepatitis Reference Centre (1979-1990) and between 1989 and 1992 served as the Commonwealth Chief Medical and Scientific Adviser on
AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual m ...
.


Achievements

Gust's public health work at the Burnet Institute is known for "...the development of vaccines against Hepatitis A and membership of the International Task Force for Hepatitis B Immunization. He established the National HIV reference laboratory and directed the National Health and Medical Research Council's special unit for AIDS virology. Since he retired in 2000, he has been director of the World Health Organization Collaborating Centre for Influenza and a member of the National Influenza Pandemic Planning Committee."


Honours and awards

In 1992, Gust was appointed an Officer of the Order of Australia for service to public health, particularly in the prevention of hepatitis and AIDS.


Publications


Books

*


Journal articles

Gust has published 205 peer-reviewed articles listed in Scopus. The most cited are: *Gust, I.D. "Epidemiological patterns of hepatitis A in different parts of the world" (1992) ''Vaccine'', 10 (SUPPL. 1), pp. S56-S58. Cited 119 times. *Gust, I.D."Epidemiology of hepatitis B infection in the Western Pacific and South East Asia" (1996) ''Gut'', 38 (SUPPL. 2), pp. S18-S23. Cited 85 times. *Doidge, C., Gust, I., Lee, A., Buck, F., Hazell, S., Manne, U. "Therapeutic immunisation against helicobacter infection (1994) ''Lancet'', 343 (8902), pp. 914–915. Cited 80 times. *Russell, C.A., Jones, T.C., Barr, I.G., Cox, N.J., Garten, R.J., Gregory, V., Gust, I.D., Hampson, A.W., Hay, A.J., Hurt, A.C., De Jong, J.C., Kelso, A., Klimov, A.I., Kageyama, T., Komadina, N., Lapedes, A.S., Lin, Y.P., Mosterin, A., Obuchi, M., Odagiri, T., Osterhaus, A.D.M.E., Rimmelzwaan, G.F., Shaw, M.W., Skepner, E., Stohr, K., Tashiro, M., Fouchier, R.A.M., Smith, D.J. "The global circulation of seasonal influenza A (H3N2) viruses" (2008) ''Science'', 320 (5874), pp. 340–346. Cited 78 times. *Fairley, C.K., Mijch, A., Gust, I.D., Nichilson, S., Dimitrakakis, M., Lucas, C.R. "The increased risk of fatal liver disease in renal transplant patients who are hepatitis Be antigen and/or HBV DNA positive" (1991) ''Transplantation'', 52 (3), pp. 497–500. Cited 46 times.


See also

*
Burnet Institute The Burnet Institute is an Australian medical institute that combines medical research in the laboratory and the field, with public health action to address major health issues affecting disadvantaged communities in Australia, and international ...
*
CSL Limited CSL Limited is an Australian multinational specialty biotechnology company that researches, develops, manufactures, and markets products to treat and prevent serious human medical conditions. CSL's product areas include blood plasma derivative ...


References

{{DEFAULTSORT:Gust, Ian 1941 births Living people People educated at Melbourne High School Alumni of the University of London Melbourne Medical School alumni University of Melbourne faculty Australian virologists Australian medical researchers Fellows of the Australian Academy of Technological Sciences and Engineering Scientists from Melbourne Australian people of Polish-Jewish descent