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Bengay
Bengay, spelled Ben-Gay before 1995, is a topical analgesic heat rub for temporary relief from muscle and joint pain associated with arthritis, bruises, simple backaches, overuse, sprains and strains. Overview Bengay was developed in France by Dr. Jules Bengué () and brought to America in 1898. The name Bengué was Anglicized and commercialized to Ben-Gay (later Bengay). It was originally produced by Pfizer Consumer Healthcare, which was acquired by Johnson & Johnson. The product is advised to be used topically for adults and children 12 years of age and older, and no more than 3 to 4 times daily. The manufacturer recommends storing it between . According to a study published by MIT Technology Review, the exact mechanism of its efficacy is not known. However, evidence indicates that it activates a neuron named TRPM8, which appears to keep minor pain signals in the brain from communicating with the spine. Hazards Bengay and similar products, such as Flexall, Mentholatu ...
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Heat Rub
Liniment (from la, linere, meaning "to anoint"), also called embrocation and heat rub, is a medicated topical preparation for application to the skin. Some liniments have viscosity similar to that of water; others are lotion or balm; still others are in transdermal patches, soft solid sticks, and sprays. Liniment usually is rubbed in to the skin, which the active ingredients penetrate. Liniments are typically sold to relieve pain and stiffness, such as from muscular aches and strains, and arthritis. These are typically formulated from alcohol, acetone, or similar quickly evaporating solvents and contain counterirritant aromatic chemical compounds, such as methyl salicilate, benzoin resin, menthol, and capsaicin. They produce a feeling of warmth within the muscle of the area they are applied to, typically acting as rubefacients via a counterirritant effect. Methyl salicylate, which is the analgesic ingredient in some heat rubs, can be toxic if used to excess. Heating pads are als ...
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Johnson & Johnson
Johnson & Johnson (J&J) is an American multinational corporation founded in 1886 that develops medical devices, pharmaceuticals, and consumer packaged goods. Its common stock is a component of the Dow Jones Industrial Average and the company is ranked No. 36 on the 2021 Fortune 500 list of the largest United States corporations by total revenue. Johnson & Johnson is one of the List of public corporations by market capitalization, world's most valuable companies, and is one of only two U.S.-based companies that has a prime credit rating of AAA, higher than that of the United States government. Johnson & Johnson is headquartered in New Brunswick, New Jersey, the consumer division being located in Skillman, New Jersey. The corporation includes some 250 subsidiary companies with operations in 60 countries and products sold in over 175 countries. Johnson & Johnson had worldwide sales of $93.8billion during calendar year 2021. Johnson & Johnson's brands include numerous household na ...
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Methyl Salicylate
Methyl salicylate (oil of wintergreen or wintergreen oil) is an organic compound with the formula C8H8O3. It is the methyl ester of salicylic acid. It is a colorless, viscous liquid with a sweet, fruity odor reminiscent of root beer, but often associatively called "minty", as it is an ingredient in mint candies. It is produced by many species of plants, particularly wintergreens. It is also produced synthetically, used as a fragrance and as a flavoring agent. Biosynthesis and occurrence Methyl salicylate was first isolated (from the plant ''Gaultheria procumbens'') in 1843 by the French chemist Auguste André Thomas Cahours (1813–1891), who identified it as an ester of salicylic acid and methanol. The biosynthesis of methyl salicylate arises via the hydroxylation of benzoic acid by a cytochrome P450 followed by methylation by a methylase enzyme. Methyl salicylate as a plant metabolite Many plants produce methyl salicylate in small quantities. Methyl salicylate levels are o ...
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Analgesic
An analgesic drug, also called simply an analgesic (American English), analgaesic (British English), pain reliever, or painkiller, is any member of the group of drugs used to achieve relief from pain (that is, analgesia or pain management). It is typically used to induce cooperation with a medical procedure. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, traditional analgesics are less effective, and there is often benefit from classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owing ...
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Chewing Gum
Chewing gum is a soft, cohesive substance designed to be chewed without being swallowed. Modern chewing gum is composed of gum base, sweeteners, softeners/plasticizers, flavors, colors, and, typically, a hard or powdered polyol coating. Its texture is reminiscent of rubber because of the physical-chemical properties of its polymer, plasticizer, and resin components, which contribute to its elastic-plastic, sticky, chewy characteristics. History The cultural tradition of chewing gum seems to have developed through a convergent evolution process, as traces of this habit have arisen separately in many early civilizations. Each early precursor to chewing gum was derived from natural growths local to the region and was chewed purely out of the instinctual desire to masticate. Early chewers did not necessarily desire to derive nutritional benefits from their chewable substances but at times sought taste stimuli and teeth cleaning or breath-freshening capabilities. Chewing gum in ...
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Trolamine Salicylate
Trolamine salicylate (Aspercreme, Aspergel) is an organic compound with the chemical formula . It is a salt of triethanolamine and salicylic acid. It is used as an ingredient in sunscreens, analgesic creams, and cosmetics. The salicylic acid portion contributes to both the sun protection effect (by absorbing UVB radiation) and to the analgesic effect. The triethanolamine neutralizes the acidity of the salicylic acid. One benefit of this topical analgesic is that it has no odor, in contrast to other topical analgesics such as menthol. The US Food and Drug Administration has not reviewed any of the over-the-counter products listed in the Daily Med database that contain trolamine salicylate. Also, the producers of trolamine salicylate products have not provided evidence to the FDA in support of claims that this chemical is directly absorbed through the skin into underlying tissue. Due to health concerns, in 2019 the FDA issued a proposed rule classifying the sunscreen use of trolami ...
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Camphor
Camphor () is a waxy, colorless solid with a strong aroma. It is classified as a terpenoid and a cyclic ketone. It is found in the wood of the camphor laurel ('' Cinnamomum camphora''), a large evergreen tree found in East Asia; and in the kapur tree ( ''Dryobalanops'' sp.), a tall timber tree from South East Asia. It also occurs in some other related trees in the laurel family, notably '' Ocotea usambarensis''. Rosemary leaves (''Rosmarinus officinalis'') contain 0.05 to 0.5% camphor, while camphorweed (''Heterotheca'') contains some 5%. A major source of camphor in Asia is camphor basil (the parent of African blue basil). Camphor can also be synthetically produced from oil of turpentine. The compound is chiral, existing in two possible enantiomers as shown in the structural diagrams. The structure on the left is the naturally occurring (+)-camphor ((1''R'',4''R'')-bornan-2-one), while its mirror image shown on the right is the (−)-camphor ((1''S'',4''S'')-bornan-2-one). ...
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Lippincott Williams & Wilkins
Lippincott Williams & Wilkins (LWW) is an American imprint of the American Dutch publishing conglomerate Wolters Kluwer. It was established by the acquisition of Williams & Wilkins and its merger with J.B. Lippincott Company in 1998. Under the LWW brand, Wolters Kluwer, through its Health Division, publishes scientific, technical, and medical content such as textbooks, reference works, and over 275 scientific journals (most of which are medical or other public health journals). Publications are aimed at physicians, nurses, clinicians, and students. Overview LWW grew out of the gradual consolidation of various earlier independent publishers by Wolters Kluwer. Predecessor Wolters Samson acquired Raven Press of New York in 1986. Wolters Samson merged with Kluwer in 1987. The merged company bought J. B. Lippincott & Co. of Philadelphia in 1990; it merged Lippincott with the Raven Press to form Lippincott-Raven in 1995. In 1997 and 1998, Wolters Kluwer acquired Thomson Science (owner ...
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The Washington Post
''The Washington Post'' (also known as the ''Post'' and, informally, ''WaPo'') is an American daily newspaper published in Washington, D.C. It is the most widely circulated newspaper within the Washington metropolitan area and has a large national audience. Daily broadsheet editions are printed for D.C., Maryland, and Virginia. The ''Post'' was founded in 1877. In its early years, it went through several owners and struggled both financially and editorially. Financier Eugene Meyer purchased it out of bankruptcy in 1933 and revived its health and reputation, work continued by his successors Katharine and Phil Graham (Meyer's daughter and son-in-law), who bought out several rival publications. The ''Post'' 1971 printing of the Pentagon Papers helped spur opposition to the Vietnam War. Subsequently, in the best-known episode in the newspaper's history, reporters Bob Woodward and Carl Bernstein led the American press's investigation into what became known as the Watergate scandal ...
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WSTM-TV
WSTM-TV (channel 3) is a television station in Syracuse, New York, United States, affiliated with NBC and The CW. It is owned by Sinclair Broadcast Group, which provides certain services to CBS affiliate WTVH (channel 5) through a local marketing agreement with Granite Broadcasting. Both stations share studios on James Street/New York State Route 290, NY 290 in the Near Northeast, Syracuse, New York, Near Northeast section of Syracuse, while WSTM-TV's transmitter is located in the town of Onondaga, New York. History The station began operations on February 15, 1950 with the call sign WSYR-TV. It was owned by Advance Publications (the Newhouse family's company) along with the ''Syracuse Post-Standard'', ''Syracuse Herald-Journal'', and WSYR radio (WSYR (AM), AM 570 and FM 94.5, now WYYY). It was Syracuse's second television station, signing on a year and three months after WHEN-TV (now WTVH). It originally had facilities at the Kemper Building in Downtown Syracuse. In 1958, WSYR-AM ...
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Chemical Burn
A chemical burn occurs when living tissue is exposed to a corrosive substance (such as a strong acid, base or oxidizer) or a cytotoxic agent (such as mustard gas, lewisite or arsine). Chemical burns follow standard burn classification and may cause extensive tissue damage. The main types of irritant and/or corrosive products are: acids, bases, oxidizers / reducing agents, solvents, and alkylants. Additionally, chemical burns can be caused by some types of cytotoxic chemical weapons, e.g., vesicants such as mustard gas and Lewisite, or urticants such as phosgene oxime. Chemical burns may: * need no source of heat * occur immediately on contact * not be immediately evident or noticeable * be extremely painful * diffuse into tissue and damage cellular structures under skin without immediately apparent damage to skin surface Presentation The exact symptoms of a chemical burn depend on the chemical involved. Symptoms include itching, bleaching or darkening of skin, burning sensati ...
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Capsaicin
Capsaicin (8-methyl-''N''-vanillyl-6-nonenamide) ( or ) is an active component of chili peppers, which are plants belonging to the genus ''Capsicum''. It is a chemical irritant for mammals, including humans, and produces a sensation of burning in any tissue with which it comes into contact. Capsaicin and several related alkaloids are called capsaicinoids and are produced as secondary metabolites by chili peppers, probably as deterrents against certain mammals and fungi.What Made Chili Peppers So Spicy?
Talk of the Nation, 15 August 2008.
Pure capsaicin is a , colorless, highly