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Alex K. Shalek
Alex K. Shalek is a biomedical engineer, and a core faculty member of the Institute for Medical Engineering and Science (IMES), an Associate Professor of Chemistry, and an Extramural Member of the Koch Institute for Integrative Cancer Research at the Massachusetts Institute of Technology. Additionally, he is a Member of the Ragon Institute and an Institute Member of the Broad Institute, an Assistant in Immunology at Massachusetts General Hospital, and an Instructor in Health Sciences and Technology at Harvard Medical School. The multi-disciplinary research of the Shalek Lab aims to create and implement broadly-applicable methods to study and engineer cellular responses in tissues, to drive biological discovery and improve prognostics, diagnostics, and therapeutics for autoimmune, infectious, and cancerous diseases. Shalek and his lab are best known for their work in single-cell genomics and for studying a number of devastating, but difficult to study, human diseases with partn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massachusetts Institute Of Technology
The Massachusetts Institute of Technology (MIT) is a private land-grant research university in Cambridge, Massachusetts. Established in 1861, MIT has played a key role in the development of modern technology and science, and is one of the most prestigious and highly ranked academic institutions in the world. Founded in response to the increasing industrialization of the United States, MIT adopted a European polytechnic university model and stressed laboratory instruction in applied science and engineering. MIT is one of three private land grant universities in the United States, the others being Cornell University and Tuskegee University. The institute has an urban campus that extends more than a mile (1.6 km) alongside the Charles River, and encompasses a number of major off-campus facilities such as the MIT Lincoln Laboratory, the Bates Center, and the Haystack Observatory, as well as affiliated laboratories such as the Broad and Whitehead Institutes. , 98 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Char ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University Faculty
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Massachusetts Institute Of Technology School Of Science Faculty
Massachusetts (Massachusett language, Massachusett: ''Muhsachuweesut [Massachusett writing systems, məhswatʃəwiːsət],'' English: , ), officially the Commonwealth of Massachusetts, is the most populous U.S. state, state in the New England region of the Northeastern United States. It borders on the Atlantic Ocean and Gulf of Maine to the east, Connecticut and Rhode Island to the south, New Hampshire and Vermont to the north, and New York (state), New York to the west. The state's capital and List of municipalities in Massachusetts, most populous city, as well as its cultural and financial center, is Boston. Massachusetts is also home to the urban area, urban core of Greater Boston, the largest metropolitan area in New England and a region profoundly influential upon American History of the United States, history, academia, and the Economy of the United States, research economy. Originally dependent on agriculture, fishing, and trade. Massachusetts was transformed into a manuf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Columbia College (New York) Alumni
Columbia College may refer to one of several institutions of higher education in North America: Canada * Columbia College (Alberta), in Calgary * Columbia College (British Columbia), a two-year liberal arts institution in Vancouver * Columbia International College, a private preparatory school in Hamilton, Ontario United States ''Listed alphabetically by state'' * Columbia College (California), a community college in Sonora, California * Columbia College Hollywood, a film school in Los Angeles, California * Columbia College (Florida), an historical college in Lake City, Florida, now merged with Stetson University * Columbia College Chicago, a large arts and communications college in Chicago, Illinois * Loras College, a private Catholic college in Dubuque, Iowa, known as Columbia College during 1920–1939 * Columbia College (Missouri), a liberal arts college in Columbia, Missouri * Columbia University, New York, known as Columbia College during 1784–1896 ** Columbia College (New ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biomedical Engineers
Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine)Biomedicine " NCI Dictionary of Cancer Medicine. . is a branch of that applies biological and physiological principles to . Biomedicine stresses standardized, evidence-based treatment validated through biological research, with treatment administered via formally trained ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doc Edgerton
Harold Eugene "Doc" Edgerton (April 6, 1903 – January 4, 1990), also known as Papa Flash, was an American scientist and researcher, a professor of electrical engineering at the Massachusetts Institute of Technology. He is largely credited with transforming the stroboscope from an obscure laboratory instrument into a common device. He also was deeply involved with the development of sonar and deep-sea photography, and his equipment was used by Jacques Cousteau in searches for shipwrecks and even the Loch Ness Monster. Biography Early years Edgerton was born in Fremont, Nebraska, on April 6, 1903, the son of Mary Nettie Coe and Frank Eugene Edgerton, a descendant of Samuel Edgerton, the son of Richard Edgerton, one of the founders of Norwich, Connecticut and Alice Ripley, a great-granddaughter of Governor William Bradford (1590–1657) of the Plymouth Colony and a passenger on the Mayflower. His father was a lawyer, journalist, author and orator and served as the assistant attorn ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanotechnology
Nanotechnology, also shortened to nanotech, is the use of matter on an atomic, molecular, and supramolecular scale for industrial purposes. The earliest, widespread description of nanotechnology referred to the particular technological goal of precisely manipulating atoms and molecules for fabrication of macroscale products, also now referred to as molecular nanotechnology. A more generalized description of nanotechnology was subsequently established by the National Nanotechnology Initiative, which defined nanotechnology as the manipulation of matter with at least one dimension sized from 1 to 100 nanometers (nm). This definition reflects the fact that quantum mechanical effects are important at this quantum-realm scale, and so the definition shifted from a particular technological goal to a research category inclusive of all types of research and technologies that deal with the special properties of matter which occur below the given size threshold. It is therefore common to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Biology
Chemical biology is a scientific discipline spanning the fields of chemistry and biology. The discipline involves the application of chemical techniques, analysis, and often small molecules produced through synthetic chemistry, to the study and manipulation of biological systems. In contrast to biochemistry, which involves the study of the chemistry of biomolecules and regulation of biochemical pathways within and between cells, chemical biology deals with chemistry ''applied to'' biology (synthesis of biomolecules, the simulation of biological systems, etc.). Introduction Some forms of chemical biology attempt to answer biological questions by studying biological systems at the chemical level. In contrast to research using biochemistry, genetics, or molecular biology, where mutagenesis can provide a new version of the organism, cell, or biomolecule of interest, chemical biology probes systems ''in vitro'' and ''in vivo'' with small molecules that have been designed for a specific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single Cell Genomics
Single-cell sequencing examines the sequence information from individual cells with optimized next-generation sequencing technologies, providing a higher resolution of cellular differences and a better understanding of the function of an individual cell in the context of its microenvironment. For example, in cancer, sequencing the DNA of individual cells can give information about mutations carried by small populations of cells. In development, sequencing the RNAs expressed by individual cells can give insight into the existence and behavior of different cell types. In microbial systems, a population of the same species can appear genetically clonal. Still, single-cell sequencing of RNA or epigenetic modifications can reveal cell-to-cell variability that may help populations rapidly adapt to survive in changing environments. Background A typical human cell consists of about 2 x 3.3 billion base pairs of DNA and 600 million mRNA bases. Usually, a mix of millions of cells is used in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aviv Regev
Aviv Regev (born July 11, 1971) is a computational biologist and systems biologist and Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche. She is a core member (on leave) at the Broad Institute of MIT and Harvard and professor (on leave) at the Department of Biology of the Massachusetts Institute of Technology. Regev is a pioneer of single cell genomics and of computational and systems biology of gene regulatory circuits. She founded and leads the Human Cell Atlas project, together with Sarah Teichmann. Education Regev studied at the Adi Lautman Interdisciplinary Program for Outstanding Students of Tel Aviv University, where she completed her Ph.D. under the supervision of Eva Jablonka and Ehud Shapiro. Career and research In 2020, Regev became the Head and Executive Vice President of Genentech Research and Early Development, based in South San Francisco, and a member of the extended Corporate Executive Committee of Roche. Previously, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Louis Brus
Louis E. Brus is the S. L. Mitchell Professor of Chemistry at Columbia University. He is the discoverer of the colloidal semi-conductor nanocrystals known as quantum dots. Brus received the Franklin Institute's 2012 Bower Award and Prize for Achievement in Science, and was chosen for the 2010 NAS Award in Chemical Sciences. He received the inaugural Kavli Prize for nanoscience in 2008, and was co-recipient of the 2006 R. W. Wood Prize of the Optical Society of America. He received the Distinguished Alumni Award from the Association of Rice University Alumni in 2010. He was elected to the United States National Academy of Sciences in 2004 and is a member of the Norwegian Academy of Science and Letters. Career In 1973, Brus joined AT&T Bell Laboratories, where he did the work that led to the discovery of quantum dots. In 1996, Brus left Bell Labs and joined the faculty in the Department of Chemistry at Columbia University Columbia University (also known as Columbia, and off ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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