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Aviv Regev
Aviv Regev (born July 11, 1971) is a computational biologist and systems biologist and Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche. She is a core member (on leave) at the Broad Institute of MIT and Harvard and professor (on leave) at the Department of Biology of the Massachusetts Institute of Technology. Regev is a pioneer of single cell genomics and of computational and systems biology of gene regulatory circuits. She founded and leads the Human Cell Atlas project, together with Sarah Teichmann. Education Regev studied at the Adi Lautman Interdisciplinary Program for Outstanding Students of Tel Aviv University, where she completed her Ph.D. under the supervision of Eva Jablonka and Ehud Shapiro. Career and research In 2020, Regev became the Head and Executive Vice President of Genentech Research and Early Development, based in South San Francisco, and a member of the extended Corporate Executive Committee of Roche. Previous ...
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Intelligent Systems For Molecular Biology
Intelligent Systems for Molecular Biology (ISMB) is an annual academic conference on the subjects of bioinformatics and computational biology organised by the International Society for Computational Biology (ISCB). The principal focus of the conference is on the development and application of advanced computational methods for biological problems. The conference has been held every year since 1993 and has grown to become one of the largest and most prestigious meetings in these fields, hosting over 2,000 delegates in 2004. From the first meeting, ISMB has been held in locations worldwide; since 2007, meetings have been located in Europe and North America in alternating years. Since 2004, European meetings have been held jointly with the European Conference on Computational Biology (ECCB). The main ISMB conference is usually held over three days and consists of presentations, poster sessions and keynote talks. Most presentations are given in multiple parallel tracks; however, k ...
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Professor
Professor (commonly abbreviated as Prof.) is an academic rank at universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who professes". Professors are usually experts in their field and teachers of the highest rank. In most systems of academic ranks, "professor" as an unqualified title refers only to the most senior academic position, sometimes informally known as "full professor". In some countries and institutions, the word "professor" is also used in titles of lower ranks such as associate professor and assistant professor; this is particularly the case in the United States, where the unqualified word is also used colloquially to refer to associate and assistant professors as well. This usage would be considered incorrect among other academic communities. However, the otherwise unqualified title "Professor" designated with a capital letter nearly always refers to a full professo ...
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Pacific Symposium On Biocomputing
The Pacific Symposium on Biocomputing (PSB) is an annual multidisciplinary scientific meeting co-founded in 1996 by Dr. Teri Klein, Dr. Lawrence Hunter and Sharon Surles. The conference is to presentation and discuss research in the theory and application of computational methods for biology. Papers and presentations are peer reviewed and published. PSB brings together researchers from the US and the Asian Pacific nations, to exchange research results and address open issues in all aspects of computational biology. PSB is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB aims for "critical mass" in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized ...
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Ï€-calculus
In theoretical computer science, the -calculus (or pi-calculus) is a process calculus. The -calculus allows channel names to be communicated along the channels themselves, and in this way it is able to describe concurrent computations whose network configuration may change during the computation. The -calculus has few terms and is a small, yet expressive language (see ). Functional programs can be encoded into the -calculus, and the encoding emphasises the dialogue nature of computation, drawing connections with game semantics. Extensions of the -calculus, such as the spi calculus and applied , have been successful in reasoning about cryptographic protocols. Beside the original use in describing concurrent systems, the -calculus has also been used to reason about business processesOMG Specification (2011)"Business Process Model and Notation (BPMN) Version 2.0" '' Object Management Group''. p.21 and molecular biology. Informal definition The -calculus belongs to the family of ...
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David Botstein
David Botstein (born September 8, 1942) is an American biologist serving as the chief scientific officer of Calico. He served as the director of the Lewis-Sigler Institute for Integrative Genomics at Princeton University from 2003 to 2013, where he remains an Anthony B. Evnin Professor of Genomics. Education Botstein graduated from the Bronx High School of Science in 1959, and Harvard University in 1963. He started his Ph.D. work under Maurice Sanford Fox at the Massachusetts Institute of Technology, then moved and received a Ph.D. from the University of Michigan in 1967 for work on P22 phage. Career Botstein taught at the Massachusetts Institute of Technology, where he became a professor of genetics. Botstein joined Genentech, Inc. in 1987 as vice president – science. In 1990, he became chairman of the Department of Genetics at Stanford University. Botstein was elected to the U.S. National Academy of Sciences in 1981 and to the Institute of Medicine in 1993. Botstein is th ...
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Eran Segal
Eran Segal ( he, ערן סגל; born 15 November 1973) is a computational biologist professor at the Weizmann Institute of Science. He works on developing quantitative models for all levels of gene regulation, including transcription, chromatin, and translation. Segal also works as an epidemiologist. He gained his BA in Computer Science and Economics from Tel Aviv University in 1998 and his PhD from Stanford University under a Fulbright Scholarship in 2004 advised by Daphne Koller. In 2007 he was awarded the Overton Prize by the International Society for Computational Biology. In 2011 he was made a professor at the Weizmann Institute of Science. Over the years, Segal published more than 140 articles in scientific and medical journals, of which about 20 in the journal ''Nature Cell Biology ''Nature Cell Biology'' is a monthly peer-reviewed scientific journal published by Nature Portfolio. It was established in 1999. The founding editor was Annette Thomas. The current edit ...
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Nature Genetics
''Nature Genetics'' is a peer-reviewed scientific journal published by Nature Portfolio. It was established in 1992. It covers research in genetics. The chief editor is Tiago Faial. The journal encompasses genetic and functional genomic studies on human traits and on other model organisms, including mouse, fly, nematode and yeast. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 41.379, ranking it 2nd out of 175 journals in the category "Genetics & Heredity". References External links Official websit ...
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Gene Expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product that enables it to produce end products, protein or non-coding RNA, and ultimately affect a phenotype, as the final effect. These products are often proteins, but in non-protein-coding genes such as transfer RNA (tRNA) and small nuclear RNA (snRNA), the product is a functional non-coding RNA. Gene expression is summarized in the central dogma of molecular biology first formulated by Francis Crick in 1958, further developed in his 1970 article, and expanded by the subsequent discoveries of reverse transcription and RNA replication. The process of gene expression is used by all known life— eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses—to generate the macromolecular machinery for life. In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenot ...
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Molecular Biology And Evolution
''Molecular Biology and Evolution'' is a monthly peer-reviewed scientific journal published by Oxford University Press on behalf of the Society for Molecular Biology and Evolution. It publishes work in the intersection of molecular biology and evolutionary biology. The founding editors-in-chief were Walter Fitch and Masatoshi Nei; the present editor-in-chief is Sudhir Kumar. According to the ''Journal Citation Reports'', the journal has a 2017 Impact Factor of 10.217, a 2018 Impact Factor of 14.797, a 2019 Impact Factor of 11.062, and a 2021 Impact Factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 8.800 References External links * Molecular and cellular biology journals Evolutionary biology journals English-language journals Monthly journals Oxford Univers ...
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Adi Lautman Interdisciplinary Program For Outstanding Students
The Adi Lautman Interdisciplinary Program for Outstanding Students is a Tel Aviv University program for fostering excellence, leading to a Master's degree. Only 15 students are admitted to the program every year. "The highly competitive selection is based on applicants’ scores in the Israeli Standardized Matriculation and Psychometric exams, a short essay, a personal interview, and a concourse examination. Thus, the students participating in the program have outstanding intellectual potential and are motivated and capable of hard work and independent thinking." The program was established in 1985 by Prof. Yehuda Elkana, to enable exceptionally gifted students to explore and conduct interdisciplinary research. Elkana led the program for nine years, until 1994. In 1995 the program was named after the late Adi Lautman, an alumnus of the program and the son of Israeli industrialist and businessman . The current head of the program is Prof. Lilach Hadany, an alumna of the program. ...
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Sarah Teichmann
Sarah Amalia Teichmann (born 1975) is a German scientist who is head of cellular genetics at the Wellcome Sanger Institute and a visiting research group leader at the European Bioinformatics Institute (EMBL-EBI). She serves as director of research (equivalent to Professor) in the Cavendish Laboratory, at the University of Cambridge and a senior research fellow at Churchill College, Cambridge. Education Teichmann was educated at the European School, Karlsruhe in Germany from 1981 to 1993 where she completed the European Baccalaureate in 1993. Teichmann went on to study the Natural Sciences Tripos at Trinity College, Cambridge and was awarded a first class Bachelor of Arts degree in 1996. In 1999, she completed her PhD supervised by Cyrus Chothia at the Laboratory of Molecular Biology (LMB) on genome evolution. Career and research Following her PhD, Teichmann did postdoctoral research supervised by Janet Thornton at University College London and funded by the Beit Memorial ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 '' Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in ...
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