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π-calculus
In theoretical computer science, the -calculus (or pi-calculus) is a process calculus. The -calculus allows channel names to be communicated along the channels themselves, and in this matter, it is able to describe concurrent computations whose network configuration may change during the computation. The -calculus has few terms and is a small, yet expressive language (see ). Functional programs can be encoded into the -calculus, and the encoding emphasises the dialogue nature of computation, drawing connections with game semantics. Extensions of the -calculus, such as the spi calculus and applied , have been successful in reasoning about cryptographic protocols. Beside the original use in describing concurrent systems, the -calculus has also been used to reason through business processes,OMG Specification (2011)"Business Process Model and Notation (BPMN) Version 2.0" ''Object Management Group''. p.21 molecular biology. and autonomous agents in artificial intelligence. Inform ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Process Calculus
In computer science, the process calculi (or process algebras) are a diverse family of related approaches for formally modelling concurrent systems. Process calculi provide a tool for the high-level description of interactions, communications, and synchronizations between a collection of independent agents or processes. They also provide algebraic laws that allow process descriptions to be manipulated and analyzed, and permit formal reasoning about equivalences between processes (e.g., using bisimulation). Leading examples of process calculi include CSP, CCS, ACP, and LOTOS. More recent additions to the family include the π-calculus, the ambient calculus, PEPA, the fusion calculus and the join-calculus. Essential features While the variety of existing process calculi is very large (including variants that incorporate stochastic behaviour, timing information, and specializations for studying molecular interactions), there are several features that all process calculi h ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Process Calculi
In computer science, the process calculi (or process algebras) are a diverse family of related approaches for formally modelling concurrent systems. Process calculi provide a tool for the high-level description of interactions, communications, and synchronizations between a collection of independent agents or processes. They also provide algebraic laws that allow process descriptions to be manipulated and analyzed, and permit formal reasoning about equivalences between processes (e.g., using bisimulation). Leading examples of process calculi include Communicating Sequential Processes, CSP, Calculus of Communicating Systems, CCS, Algebra of Communicating Processes, ACP, and Language Of Temporal Ordering Specification, LOTOS. More recent additions to the family include the Pi-calculus, π-calculus, the ambient calculus, PEPA, the fusion calculus and the join-calculus. Essential features While the variety of existing process calculi is very large (including variants that incorporat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Concurrent Computation
Concurrent computing is a form of computing in which several computations are executed ''Concurrency (computer science), concurrently''—during overlapping time periods—instead of ''sequentially—''with one completing before the next starts. This is a property of a system—whether a computer program, program, computer, or a computer network, network—where there is a separate execution point or "thread of control" for each process. A ''concurrent system'' is one where a computation can advance without waiting for all other computations to complete. Concurrent computing is a form of modular programming. In its programming paradigm, paradigm an overall computation is decomposition (computer science), factored into subcomputations that may be executed concurrently. Pioneers in the field of concurrent computing include Edsger Dijkstra, Per Brinch Hansen, and C.A.R. Hoare. Introduction The concept of concurrent computing is frequently confused with the related but distinct c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aviv Regev
Aviv Regev (Hebrew language, Hebrew: אביב רגב; born 11 July 1971) is a computational biologist and systems biologist and Executive Vice President and Head of Genentech Research and Early Development in Genentech/Roche. She is a core member (on leave) at the Broad Institute, Broad Institute of MIT and Harvard and professor (on leave) at the Department of Biology of the Massachusetts Institute of Technology. Regev is a pioneer of single cell genomics and of computational and systems biology of Gene regulatory circuit, gene regulatory circuits. She founded and leads the Human Cell Atlas project, together with Sarah Teichmann. Since 2024, she has served as a scientific advisory board member of Arc Institute. Education Regev studied at the Adi Lautman Interdisciplinary Program for Outstanding Students of Tel Aviv University, where she completed her PhD under the supervision of Eva Jablonka, and Ehud Shapiro. Career and research In 2020, Regev became the head and executive vice ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ehud Shapiro
Ehud Shapiro (; born 1955) is an Israeli scientist, entrepreneur, artist, and political activist who is Professor of Computer Science and Biology at the Weizmann Institute of Science. With international reputation, he made contributions to many scientific disciplines, laying in each a long-term research agenda by asking a basic question and offering a first step towards answering it, including how to computerize the process of scientific discovery, by providing an algorithmic interpretation to Karl Popper's methodology of conjectures and refutations; how to automate program debugging, by algorithms for fault localization; how to unify parallel, distributed, and systems programming with a high-level logic-based programming language; how to use the metaverse as a foundation for social networking; how to devise molecular computers that can function as smart programmable drugs; how to uncover the human cell lineage tree, via single-cell genomics; how to support digital democracy, by ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cryptographic Protocol
A cryptographic protocol is an abstract or concrete Communications protocol, protocol that performs a information security, security-related function and applies cryptographic methods, often as sequences of cryptographic primitives. A protocol describes how the algorithms should be used and includes details about data structures and representations, at which point it can be used to implement multiple, interoperable versions of a program. Cryptographic protocols are widely used for secure application-level data transport. A cryptographic protocol usually incorporates at least some of these aspects: * Key agreement or establishment * Entity authentication * Symmetric encryption and message authentication key (cryptography), material construction * Secured application-level data transport * Non-repudiation methods * Secret sharing methods * Secure multi-party computation For example, Transport Layer Security (TLS) is a cryptographic protocol that is used to secure web (HTTPS) conne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pacific Symposium On Biocomputing
The Pacific Symposium on Biocomputing (PSB) is an annual multidisciplinary scientific meeting co-founded in 1996 by Dr. Teri Klein, Dr. Lawrence Hunter and Sharon Surles. The conference is to presentation and discuss research in the theory and application of computational methods for biology. Papers and presentations are peer reviewed and published. PSB brings together researchers from the US and the Asian Pacific nations, to exchange research results and address open issues in all aspects of computational biology. PSB is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology. The PSB aims for "critical mass" in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
MAPK
A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. MAP kinases are found in eukaryotes only, but they are fairly diverse and encountered in all animals, fungi and plants, and even in an array of unicellular eukaryotes. MAPKs belong to the CMGC (CDK/MAPK/GSK3/CLK) kinase group. The closest relatives of MAPKs are the cyclin-dependent kinases (CDKs). Discovery The first mitogen-activated protein kinase to be discovered was ERK1 ( MAPK3) in mammals. Since ERK1 and its close relative ERK2 ( MAPK1) are both involved in growth factor signaling, the family was termed "mitogen-activated". With the discovery of other members, even from distant organis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Receptor Tyrosine Kinase
Receptor tyrosine kinases (RTKs) are the high-affinity cell surface receptors for many polypeptide growth factors, cytokines, and hormones. Of the 90 unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not only to be key regulators of normal cellular processes but also to have a critical role in the development and progression of many types of cancer. Mutations in receptor tyrosine kinases lead to activation of a series of signalling cascades which have numerous effects on protein expression. The receptors are generally activated by dimerization and substrate presentation. Receptor tyrosine kinases are part of the larger family of protein tyrosine kinases, encompassing the receptor tyrosine kinase proteins which contain a transmembrane domain, as well as the non-receptor tyrosine kinases which do not possess transmembrane domains. History The first RTKs to be discovered were the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lambda-calculus
In mathematical logic, the lambda calculus (also written as ''λ''-calculus) is a formal system for expressing computation based on function abstraction and application using variable binding and substitution. Untyped lambda calculus, the topic of this article, is a universal machine, a model of computation that can be used to simulate any Turing machine (and vice versa). It was introduced by the mathematician Alonzo Church in the 1930s as part of his research into the foundations of mathematics. In 1936, Church found a formulation which was logically consistent, and documented it in 1940. Lambda calculus consists of constructing lambda terms and performing reduction operations on them. A term is defined as any valid lambda calculus expression. In the simplest form of lambda calculus, terms are built using only the following rules: # x: A variable is a character or string representing a parameter. # (\lambda x.M): A lambda abstraction is a function definition, taking as i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
PLOS Computational Biology
''PLOS Computational Biology'' is a monthly peer-reviewed open access scientific journal covering computational biology. It was established in 2005 by the Public Library of Science in association with the International Society for Computational Biology (ISCB) in the same format as the previously established ''PLOS Biology'' and '' PLOS Medicine''. The founding editor-in-chief was Philip Bourne and the current ones are Feilim Mac Gabhann and Jason Papin. Format The journal publishes both original research and review articles. All articles are open access and licensed under the Creative Commons Attribution License. Since its inception, the journal has published the ''Ten Simple Rules'' series of practical guides, which has subsequently become one of the journal's most read article series. The ''Ten Simple Rules'' series then led to the ''Quick Tips'' collection, whose articles contain recommendations on computational practices and methods, such as dimensionality reduction for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Business Process Modeling Language
Business Process Modeling Language (BPML) is an XML-based language for business process modeling. It was maintained by the Business Process Management Initiative (BPMI) until June 2005 when BPMI and Object Management Group announced the merger of their respective business process management activities to form the Business Modeling and Integration Domain Task Force. It is deprecated since 2008. BPML was useful to OMG in order to enrich UML with process notation. History BPML, a superset of BPEL, was implemented by early stage vendors, such as Intalio Inc., but incumbents such as IBM and Microsoft did not implement BPML in their existing workflow and integration engine implementations like BizTalk or WebSphere. They pushed for the simpler language BPEL. In view of the lack of market acceptance, the BPMI dropped support of BPML in favor of BPEL4WS. Following the merger of BPMI and OMG, BPML has been definitively deprecated in 2008, with OMG's adoption of BPDM.{{cite web, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
