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Angela Grippo
Angela J. Grippo is an American neuroscientist and health psychologist known for her research on stress, mood disorders, and cardiovascular disease. She is an associate professor of psychology at Northern Illinois University. Grippo received the 2012 American Psychological Association Distinguished Scientific Award for an Early Career Contribution to Psychology in the area of health psychology. Her award citation emphasized "her creative contributions in investigating the association between depression and cardiovascular disease in preclinical animal models... hatadvance understanding of the connections among depression, stress, and physical disease in humans." In addition to her award-winning research program, Grippo writes popular articles to help people better understand themselves and their circumstances. Her article "Why Reveal Your Disability or ‘Hidden Identity’ at Work?" encourages people to remain open about their disabilities, such as dyslexia. She embraces the id ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neuroscience
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and Mathematical Modeling, mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the Biology, biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular biology, molecular and cell biology, cellular studies of individual neurons to neuroimaging, imaging ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Physiological Society
The American Physiological Society is a non-profit professional society for physiologists. It has nearly 10,000 members, most of whom hold doctoral degrees in medicine, physiology or other health professions. Its mission is to support research and education in the physiological sciences. The society publishes 16 peer reviewed journals, sponsors scientific conferences, and sponsors awards to further this mission. Governance Since it was founded in 1887, the APS has had 93 presidents lead the organization, beginning with founder Henry Bowditch and continuing through its current president, Linda C. Samuelson. The APS is governed by an elected Council consisting of the president, the president-elect, the immediate past president, and nine councilors. Management of the affairs of the society is the responsibility of a full-time executive director, appointed by and responsible to the Council. The society maintains a staff and offices in Rockville, Maryland. It conducts its operation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Women Psychologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ventricle (heart)
A ventricle is one of two large chambers toward the bottom of the heart that collect and expel blood towards the peripheral beds within the body and lungs. The blood pumped by a ventricle is supplied by an atrium, an adjacent chamber in the upper heart that is smaller than a ventricle. Interventricular means between the ventricles (for example the interventricular septum), while intraventricular means within one ventricle (for example an intraventricular block). In a four-chambered heart, such as that in humans, there are two ventricles that operate in a double circulatory system: the right ventricle pumps blood into the pulmonary circulation to the lungs, and the left ventricle pumps blood into the systemic circulation through the aorta. Structure Ventricles have thicker walls than atria and generate higher blood pressures. The physiological load on the ventricles requiring pumping of blood throughout the body and lungs is much greater than the pressure generated by the atria ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intercellular Communication
"Intercellular communication" refers to the varying ways and structures biological cells use to communicate with each other directly or through their environment. Not all cells use all of the proteins or mechanisms and there are likely to be more. Components of each type of intercellular communication may be involved in more than one type of communication making attempts at clearly separating the types of communication listed somewhat futile. The sections are loosely compiled from various areas of research rather than by a systematic attempt of classification by functional or structural characteristics. Signaling within an organism Cell signalling Simple cell signaling Single celled organisms will sense their environment to seek food and may send out signals to other cells to behave symbiotically or reproduce. A classic example of this is the slime mold. The slim mold shows how intercellular communication with a small molecule eg.cyclic AMP allows a simple organism to form from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiac Rhythmicity
Cardiac rhythmicity is the spontaneous depolarization and repolarization event that occurs in a repetitive and stable manner within the cardiac muscle. Rhythmicity is often abnormal or lost in cases of cardiac dysfunction or cardiac failure. It is the ability of the heart to maintain a relatively stable relation between its systole and diastole Diastole ( ) is the relaxed phase of the cardiac cycle when the chambers of the heart are re-filling with blood. The contrasting phase is systole when the heart chambers are contracting. Atrial diastole is the relaxing of the atria, and ventri .... Not increasing one on the expense of the other. However, external factors may lead to the disruption of the heart's rhythmicity. References * PhysioEx 6.0 by Peter Zao, Timothy Stabler, Greta Peterson, Lori Smith Cardiac electrophysiology {{circulatory-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Connexin 45
Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) and connexin 45 (Cx45) — is a protein that in humans is encoded by the ''GJC1'' gene. Function This gene is a member of the connexin gene family. The encoded protein is a component of gap junction Gap junctions are specialized intercellular connections between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regulate ...s, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. Alternatively spliced transcript variants encoding the same isoform have been described. References Further reading * * * * * * * * * * * * * * * * * * External links * * Connexins {{gene-17-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Connexin-43
Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the ''GJA1'' gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular communication (GJIC) between cells to regulate cell death, proliferation, and differentiation. As a result of its function, GJA1 is implicated in many biological processes, including muscle contraction, embryonic development, inflammation, and spermatogenesis, as well as diseases, including oculodentodigital dysplasia (ODDD), heart malformations, and cancers. Structure GJA1 is a 43.0 kDa protein composed of 382 amino acids. GJA1 contains a long C-terminal tail, an N-terminal domain, and multiple transmembrane domains. The protein passes through the phospholipid bilayer four times, leaving its C- and N-terminals exposed to the cytoplasm. The C-terminal tail is composed of 50 amino acids and includes post-translational modification si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gap Junction Protein
Gap junction proteins ;Gap junction α (GJA) proteins * GJA1, gap junction alpha-1 protein * GJA2, gap junction alpha-2 protein * GJA3, gap junction alpha-3 protein * GJA4, gap junction alpha-4 protein * GJA5, gap junction alpha-5 protein * GJA6, gap junction alpha-6 protein * GJA7, gap junction alpha-7 protein * GJA8, gap junction alpha-8 protein * GJA9, gap junction alpha-9 protein * GJA10, gap junction alpha-10 protein * GJA11, gap junction alpha-11 protein * GJA12, gap junction alpha-12 protein ;Gap junction β (GJB) proteins * GJB1, gap junction beta-1 protein * GJB2, gap junction beta-2 protein * GJB3, gap junction beta-3 protein * GJB4, gap junction beta-4 protein * GJB5, gap junction beta-5 protein * GJB6, gap junction beta-6 protein * GJB7, gap junction beta-7 protein ;Gap junction γ (GJC) proteins * GJC1, gap junction gamma-1 protein * GJC2, gap junction gamma-2 protein * GJC3, gap junction gamma-3 protein ;Gap junction δ (GJD) proteins * GJD1, gap junction delta-1 pro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anxiety
Anxiety is an emotion which is characterized by an unpleasant state of inner turmoil and includes feelings of dread over anticipated events. Anxiety is different than fear in that the former is defined as the anticipation of a future threat whereas the latter is defined as the emotional response to a real threat. It is often accompanied by nervous behavior such as pacing back and forth, somatic complaints, and rumination. Anxiety is a feeling of uneasiness and worry, usually generalized and unfocused as an overreaction to a situation that is only subjectively seen as menacing. It is often accompanied by muscular tension, restlessness, fatigue, inability to catch one's breath, tightness in the abdominal region, nausea, and problems in concentration. Anxiety is closely related to fear, which is a response to a real or perceived immediate threat (fight or flight response); anxiety involves the expectation of future threat including dread. People facing anxiety may withdraw fro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Plasma
Blood plasma is a light amber-colored liquid component of blood in which blood cells are absent, but contains proteins and other constituents of whole blood in suspension. It makes up about 55% of the body's total blood volume. It is the intravascular part of extracellular fluid (all body fluid outside cells). It is mostly water (up to 95% by volume), and contains important dissolved proteins (6–8%; e.g., serum albumins, globulins, and fibrinogen), glucose, clotting factors, electrolytes (, , , , , etc.), hormones, carbon dioxide (plasma being the main medium for excretory product transportation), and oxygen. It plays a vital role in an intravascular osmotic effect that keeps electrolyte concentration balanced and protects the body from infection and other blood-related disorders. Blood plasma is separated from the blood by spinning a vessel of fresh blood containing an anticoagulant in a centrifuge until the blood cells fall to the bottom of the tube. The blood plasma is t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Corticosterone
Corticosterone, also known as 17-deoxycortisol and 11β,21-dihydroxyprogesterone, is a 21-carbon steroid hormone of the corticosteroid type produced in the cortex of the adrenal glands. It is of minor importance in humans, except in the very rare case of congenital adrenal hyperplasia due to 17α-hydroxylase deficiency. Roles In many species, including amphibians, reptiles, rodents and birds, corticosterone is a main glucocorticoid, involved in regulation of energy, immune reactions, and stress responses. However, in humans, cortisol is the primary glucocorticoid that is produced primarily in the zona fasciculata of the adrenal cortex. Corticosterone has only weak glucocorticoid and mineralocorticoid potencies in humans and is important mainly as an intermediate in the steroidogenic pathway from pregnenolone to aldosterone. Corticosterone is converted to aldosterone by aldosterone synthase, found only in the mitochondria of glomerulosa cells. Glomerulosa cells are found in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
