Gap junction Gap junctions are specialized intercellular connections between a multitude of animal cell-types. They directly connect the cytoplasm of two cells, which allows various molecules, ions and electrical impulses to directly pass through a regulate ...

protein Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, respo ...

s ;Gap junction α (GJA) proteins *

GJA1 Gap junction alpha-1 protein (GJA1), also known as connexin 43 (Cx43), is a protein that in humans is encoded by the ''GJA1'' gene on chromosome 6. As a connexin, GJA1 is a component of gap junctions, which allow for gap junction intercellular ...

, gap junction alpha-1 protein * GJA2, gap junction alpha-2 protein *

GJA3 Gap junction alpha-3 protein is a protein that in humans is encoded by the ''GJA3'' gene. Interactions GJA3 has been shown to Protein-protein interaction, interact with Tight junction protein 1. References Further reading

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, gap junction alpha-3 protein * GJA4, gap junction alpha-4 protein * GJA5, gap junction alpha-5 protein * GJA6, gap junction alpha-6 protein * GJA7, gap junction alpha-7 protein *

GJA8 Gap junction alpha-8 protein is a protein that in humans is encoded by the ''GJA8'' gene. It is also known as connexin 50. Related gene problems *1q21.1 deletion syndrome *1q21.1 duplication syndrome *microphthalmia and other vision pathologie ...

, gap junction alpha-8 protein * GJA9, gap junction alpha-9 protein * GJA10, gap junction alpha-10 protein * GJA11, gap junction alpha-11 protein *

GJA12 Gap junction gamma-2 (GJC2), also known as connexin-46.6 (Cx46.6) and connexin-47 (Cx47) and gap junction alpha-12 (GJA12), is a protein that in humans is encoded by the ''GJC2'' gene. Function This gene encodes a gap junction protein. Gap jun ...

, gap junction alpha-12 protein ;Gap junction β (GJB) proteins *

GJB1 Gap junction beta-1 protein (GJB1), also known as connexin 32 (Cx32) is a transmembrane protein that in humans is encoded by the ''GJB1'' gene. Gap junction beta-1 protein is a member of the gap junction connexin family of proteins that regulates ...

, gap junction beta-1 protein *

GJB2 Gap junction beta-2 protein (GJB2), also known as connexin 26 (Cx26) — is a protein that in humans is encoded by the ''GJB2'' gene. Clinical significance Defects in this gene lead to the most common form of congenital deafness in developed c ...

, gap junction beta-2 protein * GJB3, gap junction beta-3 protein * GJB4, gap junction beta-4 protein * GJB5, gap junction beta-5 protein *

GJB6 Gap junction beta-6 protein (GJB6), also known as connexin 30 (Cx30) — is a protein that in humans is encoded by the ''GJB6'' gene. Connexin 30 (Cx30) is one of several gap junction proteins expressed in the inner ear. Mutations in gap junction ...

, gap junction beta-6 protein * GJB7, gap junction beta-7 protein ;Gap junction γ (GJC) proteins *

GJC1 Gap junction gamma-1 protein (GJC1), also known as gap junction alpha-7 protein (GJA7) and connexin 45 (Cx45) — is a protein that in humans is encoded by the ''GJC1'' gene. Function This gene is a member of the connexin gene family. The enco ...

, gap junction gamma-1 protein *

GJC2 Gap junction gamma-2 (GJC2), also known as connexin-46.6 (Cx46.6) and connexin-47 (Cx47) and gap junction alpha-12 (GJA12), is a protein that in humans is encoded by the ''GJC2'' gene. Function This gene encodes a gap junction protein. Gap ju ...

, gap junction gamma-2 protein *

GJC3 Gap junction gamma-3, also known as connexin-29 (Cx29) or gap junction epsilon-1 (GJE1), is a protein that in humans is encoded by the ''GJC3'' gene. GJC3 is a conexin. Function This gene encodes a gap junction protein. The encoded protein is ...

, gap junction gamma-3 protein ;Gap junction δ (GJD) proteins * GJD1, gap junction delta-1 protein *

GJD2 Gap junction delta-2 protein (GJD2) also known as connexin-36 (Cx36) or gap junction alpha-9 protein (GJA9) is a protein that in humans is encoded by the ''GJD2'' gene. Function GJD2, also called connexin-36 (CX36), is a member of the connexin ...

, gap junction delta-2 protein * GJD3, gap junction delta-3 protein * GJD4, gap junction delta-4 protein

See also