Amiton
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Amiton
VG (IUPAC name: ''O'',''O''-diethyl ''S''- -(diethylamino)ethylphosphorothioate) (also called Amiton or Tetram) is a "V-series" nerve agent chemically similar to the better-known VX nerve agent. Tetram is the common Russian name for the substance. Amiton was the trade name for the substance when it was marketed as an insecticide by ICI in the mid-1950s. Chemical With a toxicity of about 1/10 that of VX, i.e. similar to that of sarin, it is now considered too dangerous for use in agriculture but unlike other nerve agents it is classified under Schedule 2 of the Chemical Weapons Convention rather than the more restrictive Schedule 1. It is thought that North Korea may have military stockpiles of this chemical . During the early 1950s at least three chemical companies working on organo-phosphorus insecticides independently discovered the severe toxicity of these chemicals. In 1952, Dr. Ranajit Ghosh, a chemist working for ICI at their Plant Protection Laboratories at Jealott's ...
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VX (nerve Agent)
VX is an extremely toxic synthetic chemical compound in the organophosphorus class, specifically, a thiophosphonate. In the class of nerve agents, it was developed for military use in chemical warfare after translation of earlier discoveries of organophosphate toxicity in pesticide research. In recent years, VX was found to be the agent used in the assassination of Kim Jong-nam. In its pure form, VX is an oily, relatively non-volatile liquid that is amber-like in colour. Because of its low volatility, VX persists in environments where it is dispersed. VX, short for "venomous agent X", is one of the best known of the V nerve agents and was first discovered at Porton Down by Ranajit Ghosh in England during the early 1950s based on research first done by Gerhard Schrader, a chemist working for IG Farben in Germany during the 1930s. It is now one of a broader V-series of agents which are classified as nerve agents and have been used as a chemical weapon in various recorded dead ...
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List Of Extremely Hazardous Substances
This is the list of extremely hazardous substances defined in Section 302 of the U.S. Emergency Planning and Community Right-to-Know Act (42 U.S.C. 11002). The list can be found as an appendix to 40 C.F.R. 355. Updates as of 2006 can be seen on the Federal Register, 71 FR 47121 (August 16, 2006). The data were provided by the United States Environmental Protection Agency (EPA). __NOTOC__ A * Acetone cyanohydrin * Acetone thiosemicarbazide * Acrolein * Acrylamide * Acrylonitrile * Acryloyl chloride * Adiponitrile * Aldicarb * Aldrin * Allyl alcohol * Allylamine * Aluminum phosphide * Aminopterin * Amiton * Amiton oxalate * Ammonia * Amphetamine * Aniline * Aniline, 2,4,6-trimethyl- * Antimony pentafluoride * Antimycin A * ANTU (Alpha-Naphthylthiourea) * Arsenic pentoxide * Arsenous oxide * Arsenous trichloride * Arsine * Azinphos-ethyl * Azinphos-methyl B * Benzal chloride * Benzenamine, 3-(trifluoromethyl)- * Benzenearsonic acid * Benzimidazole, 4,5-dichloro-2-(tri ...
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Nerve Agent
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter. Nerve agents are acetylcholinesterase inhibitors used as poison. Poisoning by a nerve agent leads to constriction of pupils, profuse salivation, convulsions, and involuntary urination and defecation, with the first symptoms appearing in seconds after exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to the loss of the body's control over respiratory and other muscles. Some nerve agents are readily vaporized or aerosolized, and the primary portal of entry into the body is the respiratory system. Nerve agents can also be absorbed through the skin, requiring that those likely to be subjected to such agents wear a full body suit in addition to a respirato ...
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Nerve Agent
Nerve agents, sometimes also called nerve gases, are a class of organic chemicals that disrupt the mechanisms by which nerves transfer messages to organs. The disruption is caused by the blocking of acetylcholinesterase (AChE), an enzyme that catalyzes the breakdown of acetylcholine, a neurotransmitter. Nerve agents are acetylcholinesterase inhibitors used as poison. Poisoning by a nerve agent leads to constriction of pupils, profuse salivation, convulsions, and involuntary urination and defecation, with the first symptoms appearing in seconds after exposure. Death by asphyxiation or cardiac arrest may follow in minutes due to the loss of the body's control over respiratory and other muscles. Some nerve agents are readily vaporized or aerosolized, and the primary portal of entry into the body is the respiratory system. Nerve agents can also be absorbed through the skin, requiring that those likely to be subjected to such agents wear a full body suit in addition to a respirato ...
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List Of Schedule 2 Substances (CWC)
Schedule 2 substances, in the sense of the Chemical Weapons Convention, are chemicals that can either be used as chemical weapons themselves or used in the manufacture of chemical weapons but that have small-scale applications outside of chemical warfare and so can be legitimately manufactured in small quantities. An example is thiodiglycol, which can be used in the manufacture of mustard agents but is also used as a solvent in inks. Manufacture must be declared as their production is subject to declaration to the Organisation for the Prohibition of Chemical Weapons (OPCW) per Part VII of the "Verification Annex", and they may not be exported to countries that are not party to the Convention. As with the other schedules, they are sub-divided into Part A substances, which are chemicals that can be used directly as weapons, and Part B, which are precursors useful in the manufacture of chemical weapons. The Schedule 2 list is one of three lists. Chemicals that can be used as weapon ...
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IUPAC
The International Union of Pure and Applied Chemistry (IUPAC ) is an international federation of National Adhering Organizations working for the advancement of the chemical sciences, especially by developing nomenclature and terminology. It is a member of the International Science Council (ISC). IUPAC is registered in Zürich, Switzerland, and the administrative office, known as the "IUPAC Secretariat", is in Research Triangle Park, North Carolina, United States. This administrative office is headed by IUPAC's executive director, currently Lynn Soby. IUPAC was established in 1919 as the successor of the International Congress of Applied Chemistry for the advancement of chemistry. Its members, the National Adhering Organizations, can be national chemistry societies, national academies of sciences, or other bodies representing chemists. There are fifty-four National Adhering Organizations and three Associate National Adhering Organizations. IUPAC's Inter-divisional Committee on ...
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Porton Down
Porton Down is a science park in Wiltshire, England, just northeast of the village of Porton, near Salisbury. It is home to two British government facilities: a site of the Ministry of Defence's Defence Science and Technology Laboratory (Dstl) – known for over 100 years as one of the UK's most secretive and controversial military research facilities, occupying – and a site of the UK Health Security Agency. It is also home to other private and commercial science organisations, and is expanding to attract other companies. Location Porton Down is located just northeast of the village of Porton near Salisbury, in Wiltshire, England. To the northwest lies the MoD Boscombe Down airfield operated by QinetiQ. On some maps, the land surrounding the complex is identified as a "Danger Area". History of government use Porton Down opened in 1916 as the War Department Experimental Station, shortly thereafter renamed the Royal Engineers Experimental Station, for testing chemical w ...
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V-series Nerve Agents
V series or V-series may refer to: * Cadillac V series, a line of high-performance vehicles * List of ITU-T V-series recommendations, on data communication over the telephone network * LG V series, a line of high-end Android devices * V series of Sony Ericsson phones, exclusive to Vodafone * V-series of nerve agents: ** VE (nerve agent) ** VG (nerve agent) ** VM (nerve agent) ** VR (nerve agent) ** VS (nerve agent) ** VX (nerve agent) * V (TV series), the name of several TV series * V Series (Sweden), a TV channel See also * U series (other) * W series (other) W series or W-series may refer to: * Dodge W series, 4x4 versions of Dodge D series * GMC W series or Chevrolet W series – versions of the Isuzu Elf trucks * Kawasaki W series, motorcycles * NRIST W-series UAV, Chinese unmanned aerial vehicle l ...
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Acetylcholinesterase Inhibitors
Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ganglia and neuromuscular junctions, which are rich in acetylcholine receptors. Acetylcholinesterase inhibitors are one of two types of cholinesterase inhibitors; the other being butyryl-cholinesterase inhibitors. Acetylcholinesterase is the primary member of the cholinesterase enzyme family. Acetylcholinesterase inhibitors are classified as reversible, irreversible, or quasi-irreversible (also called pseudo-irreversible). Mechanism of action Organophosphates Organophosphates like TEPP and sarin inhibit cholinesterases, enzymes that hydrolyze the neurotransmitter acetylcholine. The active centre of cholinesterases feature two important sites, namely th ...
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United States Government Publishing Office
The United States Government Publishing Office (USGPO or GPO; formerly the United States Government Printing Office) is an agency of the legislative branch of the United States Federal government. The office produces and distributes information products and services for all three branches of the Federal Government, including U.S. passports for the Department of State as well as the official publications of the Supreme Court, the Congress, the Executive Office of the President, executive departments, and independent agencies. An act of Congress changed the office's name to its current form in 2014. History The Government Printing Office was created by congressional joint resolution () on June 23, 1860. It began operations March 4, 1861, with 350 employees and reached a peak employment of 8,500 in 1972. The agency began transformation to computer technology in the 1980s; along with the gradual replacement of paper with electronic document distribution, this has led to a stea ...
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Emergency Planning And Community Right-to-Know Act
The Emergency Planning and Community Right-to-Know Act of 1986 is a United States federal law passed by the 99th United States Congress located at Title 42, Chapter 116 of the U.S. Code, concerned with emergency response preparedness. On October 17, 1986, President Ronald Reagan signed into law the Superfund Amendments and Reauthorization Act of 1986 (SARA). This act amended the Comprehensive Environmental Response, Compensation, and Liability Act of 1980 (CERCLA), commonly known as Superfund. A free-standing law, the Emergency Planning and Community Right-to-Know Act of 1986 (EPCRA) was commonly known as SARA Title III. Its purpose is to encourage and support emergency planning efforts at the state and local levels and to provide the public and local governments with information concerning potential chemical hazards present in their communities. Background During the early morning hours of December 3, 1984, a Union Carbide plant in a village just South of Bhopal, India rel ...
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