1510 Influenza Pandemic
In 1510, an acute respiratory disease emerged in Asia before spreading through North Africa and Europe during the first chronicled, inter-regional flu pandemic generally recognized by medical historians and epidemiologists. Influenza-like illnesses had been documented in Europe since at least Charlemagne, with 1357's outbreak the first to be called ''influenza'', but the 1510 flu pandemic is the first to be pathologically described following communication advances brought about by the printing press. Flu became more widely referred to as ''coqueluche'' and ''coccolucio'' in France and Sicily during this pandemic, variations of which became the most popular names for flu in early modern Europe. The pandemic caused significant disruption in government, church, and society with near-universal infection and a mortality rate of around 1%. Asia The 1510 flu is suspected of originating in East Asia, possibly China. Gregor Horst writes in ''Operum medicorum tombus primus'' (1661) that th ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Influenza
Influenza, commonly known as "the flu", is an infectious disease caused by influenza viruses. Symptoms range from mild to severe and often include fever, runny nose, sore throat, muscle pain, headache, coughing, and fatigue. These symptoms begin from one to four days after exposure to the virus (typically two days) and last for about 2–8 days. Diarrhea and vomiting can occur, particularly in children. Influenza may progress to pneumonia, which can be caused by the virus or by a subsequent bacterial infection. Other complications of infection include acute respiratory distress syndrome, meningitis, encephalitis, and worsening of pre-existing health problems such as asthma and cardiovascular disease. There are four types of influenza virus, termed influenza viruses A, B, C, and D. Aquatic birds are the primary source of Influenza A virus (IAV), which is also widespread in various mammals, including humans and pigs. Influenza B virus (IBV) and Influenza C virus (ICV) pri ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Thomas Short (physician)
Thomas Short (1690–1772) was an English physician, epidemiologist, and medical historian. He is known for writing extensively on population theory and the history of disease outbreaks affecting England. Life and career A draft deed indicates Thomas Short was the son of a merchant named James Short. From an early point in Thomas's life he was interested in chemistry and mineral water, and as a young man was educated in medicine at Trinity College in Oxford. After his studies he either practiced medicine or was counseled in Coventry from 1723 to 1728, and Short began officially working as a physician in Sheffield around 1725 or 1728. He published books about what he learned as a doctor treating patients. One of Short's earliest publications, in 1728, was medical literature on the negative health effects of obesity: In ''A Discourse concerning the causes and effects of Corpulency, etc'' he writes about how fat separates from the blood and why some individuals are more vulnerable ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mellingen
Mellingen is a historic town and a municipality in the district of Baden in the canton of Aargau in Switzerland. The town is located on the Reuss. History Mellingen is first mentioned in 1045 as ''Mellingen'' though this comes from a 16th-century copy of the original. Around 1217–39 it was mentioned as ''Menelingen''. Geography Mellingen has an area, , of . Of this area, 36.2% is used for agricultural purposes, while 32.4% is forested. Of the rest of the land, 26.7% is settled (buildings or roads) and the remainder (4.8%) is non-productive (rivers or lakes). The municipality is located in the Baden district. The compact, walled medieval city center straddles the river Reuss. The old city is surrounded by a number of newer settlements. It has grown into a center of the small ''Unteres Reusstal'' region. Coat of arms The blazon of the municipal coat of arms is ''"Or a Lion rampant Gules and in chief of the last a Bar uletArgent."'' Demographics Mellingen has a population ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Holy Roman Empire
The Holy Roman Empire was a Polity, political entity in Western Europe, Western, Central Europe, Central, and Southern Europe that developed during the Early Middle Ages and continued until its Dissolution of the Holy Roman Empire, dissolution in 1806 during the Napoleonic Wars. From the accession of Otto I in 962 until the twelfth century, the Empire was the most powerful monarchy in Europe. Andrew Holt characterizes it as "perhaps the most powerful European state of the Middle Ages". The functioning of government depended on the harmonic cooperation (dubbed ''consensual rulership'' by Bernd Schneidmüller) between monarch and vassals but this harmony was disturbed during the Salian Dynasty, Salian period. The empire reached the apex of territorial expansion and power under the House of Hohenstaufen in the mid-thirteenth century, but overextending led to partial collapse. On 25 December 800, Pope Leo III crowned the List of Frankish kings, Frankish king Charlemagne as Carolingi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Switzerland
). Swiss law does not designate a ''capital'' as such, but the federal parliament and government are installed in Bern, while other federal institutions, such as the federal courts, are in other cities (Bellinzona, Lausanne, Luzern, Neuchâtel, St. Gallen a.o.). , coordinates = , largest_city = Zürich , official_languages = , englishmotto = "One for all, all for one" , religion_year = 2020 , religion_ref = , religion = , demonym = , german: Schweizer/Schweizerin, french: Suisse/Suissesse, it, svizzero/svizzera or , rm, Svizzer/Svizra , government_type = Federalism, Federal assembly-independent Directorial system, directorial republic with elements of a direct democracy , leader_title1 = Federal Council (Switzerland), Federal Council , leader_name1 = , leader_title2 = , leader_name2 = Walter Thurnherr , legislature = Fe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Achilles Pirminius Gasser
In Greek mythology, Achilles ( ) or Achilleus ( grc-gre, Ἀχιλλεύς) was a hero of the Trojan War, the greatest of all the Greek warriors, and the central character of Homer's ''Iliad''. He was the son of the Nereid Thetis and Peleus, king of Phthia. Achilles' most notable feat during the Trojan War was the slaying of the Trojan prince Hector outside the gates of Troy. Although the death of Achilles is not presented in the ''Iliad'', other sources concur that he was killed near the end of the Trojan War by Paris, who shot him with an arrow. Later legends (beginning with Statius' unfinished epic ''Achilleid'', written in the 1st century AD) state that Achilles was invulnerable in all of his body except for one heel, because when his mother Thetis dipped him in the river Styx as an infant, she held him by one of his heels. Alluding to these legends, the term "Achilles' heel" has come to mean a point of weakness, especially in someone or something with an otherwise strong c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Holy See
The Holy See ( lat, Sancta Sedes, ; it, Santa Sede ), also called the See of Rome, Petrine See or Apostolic See, is the jurisdiction of the Pope in his role as the bishop of Rome. It includes the apostolic episcopal see of the Diocese of Rome, which has ecclesiastical jurisdiction over the Catholic Church and the sovereign city-state known as the Vatican City. According to Catholic tradition it was founded in the first century by Saints Peter and Paul and, by virtue of Petrine and papal primacy, is the focal point of full communion for Catholic Christians around the world. As a sovereign entity, the Holy See is headquartered in, operates from, and exercises "exclusive dominion" over the independent Vatican City State enclave in Rome, of which the pope is sovereign. The Holy See is administered by the Roman Curia (Latin for "Roman Court"), which is the central government of the Catholic Church. The Roman Curia includes various dicasteries, comparable to ministries and ex ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rome
, established_title = Founded , established_date = 753 BC , founder = King Romulus (legendary) , image_map = Map of comune of Rome (metropolitan city of Capital Rome, region Lazio, Italy).svg , map_caption = The territory of the ''comune'' (''Roma Capitale'', in red) inside the Metropolitan City of Rome (''Città Metropolitana di Roma'', in yellow). The white spot in the centre is Vatican City. , pushpin_map = Italy#Europe , pushpin_map_caption = Location within Italy##Location within Europe , pushpin_relief = yes , coordinates = , coor_pinpoint = , subdivision_type = Country , subdivision_name = Italy , subdivision_type2 = Region , subdivision_name2 = Lazio , subdivision_type3 = Metropolitan city , subdivision_name3 = Rome Capital , government_footnotes= , government_type = Strong Mayor–Council , leader_title2 = Legislature , leader_name2 = Capitoline Assemb ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Pope Julius II
Pope Julius II ( la, Iulius II; it, Giulio II; born Giuliano della Rovere; 5 December 144321 February 1513) was head of the Catholic Church and ruler of the Papal States from 1503 to his death in February 1513. Nicknamed the Warrior Pope or the Fearsome Pope, he chose his papal name not in honour of Pope Julius I but in emulation of Julius Caesar. One of the most powerful and influential popes, Julius II was a central figure of the High Renaissance and left a significant cultural and political legacy. As a result of his policies during the Italian Wars, the Papal States increased its power and centralization, and the office of the papacy continued to be crucial, diplomatically and politically, during the entirety of the 16th century in Italy and Europe. In 1506, Julius II established the Vatican Museums and initiated the rebuilding of the St. Peter's Basilica. The same year he organized the famous Swiss Guards for his personal protection and commanded a successful campa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Modena
Modena (, , ; egl, label=Emilian language#Dialects, Modenese, Mòdna ; ett, Mutna; la, Mutina) is a city and ''comune'' (municipality) on the south side of the Po Valley, in the Province of Modena in the Emilia-Romagna region of northern Italy. A town, and seat of an archbishop, it is known for its car industry since the factories of the famous Italian upper-class sports car makers Ferrari, De Tomaso, Lamborghini, Pagani (automobile), Pagani and Maserati are, or were, located here and all, except Lamborghini, have headquarters in the city or nearby. One of Ferrari's cars, the Ferrari 360, 360 Modena, was named after the town itself. Ferrari's production plant and Formula One team Scuderia Ferrari are based in Maranello south of the city. The University of Modena, founded in 1175 and expanded by Francesco II d'Este in 1686, focuses on economics, medicine and law, and is the second oldest :wikt:athenaeum, athenaeum in Italy. Italian military officers are trained at the Milit ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Emilia-Romagna
egl, Emigliàn (man) egl, Emiglièna (woman) rgn, Rumagnòl (man) rgn, Rumagnòla (woman) it, Emiliano (man) it, Emiliana (woman) or it, Romagnolo (man) it, Romagnola (woman) , population_note = , population_blank1_title = , population_blank1 = , demographics_type1 = , demographics1_footnotes = , demographics1_title1 = , demographics1_info1 = , demographics1_title2 = , demographics1_info2 = , demographics1_title3 = , demographics1_info3 = , timezone1 = CET , utc_offset1 = +1 , timezone1_DST = CEST , utc_offset1_DST = +2 , postal_code_type = , postal_code = , area_code_type = ISO 3166 code , area_code = IT-45 , blank_name_sec1 = GDP (nominal) , blank_info_se ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Sicily
(man) it, Siciliana (woman) , population_note = , population_blank1_title = , population_blank1 = , demographics_type1 = Ethnicity , demographics1_footnotes = , demographics1_title1 = Sicilian , demographics1_info1 = 98% , demographics1_title2 = , demographics1_info2 = , demographics1_title3 = , demographics1_info3 = , timezone1 = CET , utc_offset1 = +1 , timezone1_DST = CEST , utc_offset1_DST = +2 , postal_code_type = , postal_code = , area_code_type = ISO 3166 code , area_code = IT-82 , blank_name_sec1 = GDP (nominal) , blank_info_sec1 = €89.2 billion (2018) , blank1_name_sec1 = GDP per capita , blank1_info_sec1 ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |