Ștefan S. Nicolau
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Ștefan S. Nicolau
Ștefan S. Nicolau (15 February 1896 – 15 October 1967) was a Romanian physician who is considered to be the founder of the Romanian school of virology. In 1948, he was elected a titular member of the Romanian Academy. Biography He was born in Bucharest and graduated from the Matei Basarab High School in 1913. He started his medical studies at the University of Bucharest, but was conscripted into the Army once Romania entered World War I in August 1916. He served under Mihai Ciucă as a medical second lieutenant on the Moldavian front and worked at the 2nd Hospital for Contagious Diseases. After the war, Nicolau obtained his MD degree in 1920 from the Faculty of Medicine in Cluj. He pursued his medical training in Paris, where he worked at the Pasteur Institute from 1920 to 1939, where he started as Assistant, then advancing to Associate, and finally to Head of Laboratory. Nicolau obtained his Ph.D. from Sorbonne University in 1925. At the Pasteur Institute, he was ...
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Bucharest
Bucharest ( , ; ro, București ) is the capital and largest city of Romania, as well as its cultural, industrial, and financial centre. It is located in the southeast of the country, on the banks of the Dâmbovița River, less than north of the Danube River and the Bulgarian border. Bucharest was first mentioned in documents in 1459. The city became the capital of Romania in 1862 and is the centre of Romanian media, culture, and art. Its architecture is a mix of historical (mostly Eclectic, but also Neoclassical and Art Nouveau), interbellum ( Bauhaus, Art Deco and Romanian Revival architecture), socialist era, and modern. In the period between the two World Wars, the city's elegant architecture and the sophistication of its elite earned Bucharest the nickname of 'Paris of the East' ( ro, Parisul Estului) or 'Little Paris' ( ro, Micul Paris). Although buildings and districts in the historic city centre were heavily damaged or destroyed by war, earthquakes, and even Nic ...
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List Of Members Of The Romanian Academy
This is a list of members of the Romanian Academy. References * Academia RomânăMembrii Academiei Române din 1866 până în prezent External links {{commons category-inline, Members of the Romanian Academy Members of the Romanian Academy Academicians Romania Romania ( ; ro, România ) is a country located at the crossroads of Central Europe, Central, Eastern Europe, Eastern, and Southeast Europe, Southeastern Europe. It borders Bulgaria to the south, Ukraine to the north, Hungary to the west, S ...
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Genome
In the fields of molecular biology and genetics, a genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of 'junk' DNA with no evident function. Almost all eukaryotes have mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been sequenced and various regions have been annotated. The International Human Genome Project reported the sequence of the genome for ''Homo sapiens'' in 200The Human Genome Project although the initial "finished" sequence was missing 8% of the genome consisting mostly of repetitive sequences. With advancements in technology that could handle sequenci ...
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Macromolecule
A macromolecule is a very large molecule important to biophysical processes, such as a protein or nucleic acid. It is composed of thousands of covalently bonded atoms. Many macromolecules are polymers of smaller molecules called monomers. The most common macromolecules in biochemistry are biopolymers (nucleic acids, proteins, and carbohydrates) and large non-polymeric molecules such as lipids, nanogels and macrocycles. Synthetic fibers and experimental materials such as carbon nanotubes are also examples of macromolecules. Definition The term ''macromolecule'' (''macro-'' + ''molecule'') was coined by Nobel laureate Hermann Staudinger in the 1920s, although his first relevant publication on this field only mentions ''high molecular compounds'' (in excess of 1,000 atoms). At that time the term ''polymer'', as introduced by Berzelius in 1832, had a different meaning from that of today: it simply was another form of isomerism for example with benzene and acetylene and had litt ...
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Antigen
In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term ''antigen'' originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids. Antigens are recognized by antigen receptors, including antibodies and T-cell receptors. Diverse antigen receptors are made by cells of the immune system so that each cell has a specificity for a single antigen. Upon exposure to an antigen, only the lymphocytes that recognize that antigen are activated and expanded, a process known as clonal selection. In most cases, an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may cross-react and bind more than one antigen. ...
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Collodion
Collodion is a flammable, syrupy solution of nitrocellulose in ether and alcohol. There are two basic types: flexible and non-flexible. The flexible type is often used as a surgical dressing or to hold dressings in place. When painted on the skin, collodion dries to form a flexible nitrocellulose film. While it is initially colorless, it discolors over time. Non-flexible collodion is often used in theatrical make-up. Collodion was also the basis of most wet-plate photography until it was superseded by modern gelatin emulsions. History In 1846 Louis-Nicolas Ménard and Florès Domonte discovered that cellulose nitrate could be dissolved in ether. They devised a mixture of ether (ethoxyethane) as the solvent and ethanol as a diluent that rendered cellulose nitrate into a clear gelatinous liquid. Collodion was first used medically as a dressing in 1847 by the Boston physician John Parker Maynard. The solution was dubbed "collodion" (from the Greek κολλώδης (''kollodis''), g ...
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Ultrafiltration
Ultrafiltration (UF) is a variety of membrane filtration in which forces such as pressure or concentration gradients lead to a separation through a semipermeable membrane. Suspended solids and solutes of high molecular weight are retained in the so-called retentate, while water and low molecular weight solutes pass through the membrane in the permeate (filtrate). This separation process is used in industry and research for purifying and concentrating macromolecular (103–106 Da) solutions, especially protein solutions. Ultrafiltration is not fundamentally different from microfiltration. Both of these separate based on size exclusion or particle capture. It is fundamentally different from membrane gas separation, which separate based on different amounts of absorption and different rates of diffusion. Ultrafiltration membranes are defined by the molecular weight cut-off (MWCO) of the membrane used. Ultrafiltration is applied in cross-flow or dead-end mode. Applications Ind ...
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Constantin Levaditi
Constantin Levaditi (1 August 1874 – 5 September 1953) was a Romanian physician and microbiologist, a major figure in virology and immunology, especially in the study of poliomyelitis and syphilis. Biography He was born in Galați. His father, Spyridon Livaditis, of Greek descent (from Macedonia) was 30 years old and working as a customs officer. His mother, Ioana Ștefănescu, then aged 18 years, was the daughter of peasants from Focșani. The family name originates from the name of the town of Livadia (Livaditis means one who comes from Livadia). The researcher (1901–1987) reported that Spyridon Livaditis was a member of the Filiki Eteria (Society of Friends), established to organize the Greek Revolution of 1821 against the Ottoman Empire under the leadership of Prince Alexander Ypsilantis. He studied at Matei Basarab High School in Bucharest and at the Carol Davila University of Medicine and Pharmacy, where he studied under Victor Babeș. He then trained at the C ...
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Paris
Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. Since the 17th century, Paris has been one of the world's major centres of finance, diplomacy, commerce, fashion, gastronomy, and science. For its leading role in the arts and sciences, as well as its very early system of street lighting, in the 19th century it became known as "the City of Light". Like London, prior to the Second World War, it was also sometimes called the capital of the world. The City of Paris is the centre of the ÃŽle-de-France region, or Paris Region, with an estimated population of 12,262,544 in 2019, or about 19% of the population of France, making the region France's primate city. The Paris Region had a GDP of €739 billion ($743 billion) in 2019, which is the highest in Europe. According to the Economist Intelli ...
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Doctor Of Medicine
Doctor of Medicine (abbreviated M.D., from the Latin language, Latin ''Medicinae Doctor'') is a medical degree, the meaning of which varies between different jurisdictions. In the United States, and some other countries, the M.D. denotes a professional degree. This generally arose because many in 18th-century medical professions trained in Scotland, which used the M.D. degree nomenclature. In England, however, Bachelor of Medicine, Bachelor of Surgery was used and eventually in the 19th century became the standard in Scotland too. Thus, in the United Kingdom, Republic of Ireland, Ireland and other countries, the M.D. is a research doctorate, honorary degree, honorary doctorate or applied clinical degree restricted to those who already hold a professional degree (Bachelor's/Master's/Doctoral) in medicine. In those countries, the equivalent professional degree to the North American, and some others use of M.D., is still typically titled Bachelor of Medicine, Bachelor of Surgery (M.B ...
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Romania In World War I
The Kingdom of Romania was neutral for the first two years of World War I, entering on the side of the Allied powers from 27 August 1916 until Central Power occupation led to the Treaty of Bucharest in May 1918, before reentering the war on 10 November 1918. It had the most significant oil fields in Europe, and Germany eagerly bought its petroleum, as well as food exports. From the point of view of its belligerent status, Romania was a neutral country between 28 July 1914 and 27 August 1916, a belligerent country on the part of the Entente from 27 August 1916 to 9 December 1917, in a state of armistice with the Central Powers from 10 December 1917 to 7 May 1918, a non-combatant country between 7 May 1918 and 10 November 1918, and finally a belligerent country in the Entente between 10 and 11 November 1918. At the start of World War I, King Carol I of Romania favored Germany, while the nation's political elite favored the Entente. As such, the crown council took the decision to ...
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Mihai Ciucă
Mihai Ciucă (18 August 1883–20 February 1969) was a Romanian bacteriologist and parasitologist. Biography He was born into a family of teachers in Săveni, Dorohoi County, in the Moldavia region, and spent his childhood in his native village. He attended A. T. Laurian High School in BotoÈ™ani, followed by the Boarding High School in IaÈ™i, which he completed in 1901. In 1907, he obtained a doctorate in medicine from the University of Bucharest. Ciucă subsequently went to France, where he trained in the microbiology laboratories of Pierre Paul Émile Roux, Albert Calmette, and Constantin Levaditi, as well as in the protozoology laboratory of Félix Mesnil and Charles Louis Alphonse Laveran. He became a hospital physician in 1907, and would remain as such until 1934. A participant in the Second Balkan War,
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