Topic summary

Thymine

Names Preferred IUPAC name
5-Methylpyrimidine-2,4(1H,3H)-dione
Other names
5-Methyluracil
Identifiers
3D model (JSmol)
ChEBIChEMBLChemSpiderECHA InfoCard100.000.560MeSHThymineUNII
  • InChI=1S/C5H6N2O2/c1-3-2-6-5(9)7-4(3)8/h2H,1H3,(H2,6,7,8,9)
    Key: RWQNBRDOKXIBIV-UHFFFAOYSA-N
  • O=C1NC(=O)NC=C1C
Properties C5H6N2O2Molar mass126.115 g·mol Density1.223 g cm (calculated) Melting point316 to 317 °C (601 to 603 °F; 589 to 590 K) Boiling point335 °C (635 °F; 608 K) (decomposes) 3.82 g/L Acidity (pKa) 9.7
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Thymine () (symbolT or Thy) is one of the four nucleotide bases in the nucleic acid of DNA that are represented by the letters G–C–A–T. The others are adenine, guanine, and cytosine. Thymine is also known as 5-methyluracil, a pyrimidine nucleobase. In RNA, thymine is replaced by the nucleobase uracil. Thymine was first isolated in 1893 by Albrecht Kossel and Albert Neumann from calf thymus glands, hence its name.