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Butyronitrile

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Names Preferred IUPAC nameButanenitrileOther names 1-CyanopropanePropyl cyaniden-ButyronitrileIdentifiers CAS Number109-74-03D model (JSmol)Interactive imageBeilstein Reference1361452 ChEBICHEBI:51937ChemSpider7717ECHA InfoCard100.003.365EC Number203-700-6MeSHN-butyronitrilePubChemCID8008RTECS numberET8750000UNIIO3V36V0W0MUN number2411 CompTox Dashboard(EPA)DTXSID1026823InChIInChI=1S/C4H7N/c1-2-3-4-5/h2-3H2,1H3Key: KVNRLNFWIYMESJ-UHFFFAOYSA-NSMILESCCCC#NProperties Chemical formulaC4H7NMolar mass69.107 g·mol Appear…

EtifelmineEtifelmineEtifelmine (INN; also known as gilutensin) is a stimulant drug. It was used for the treatment of hypotension (low blood pressure). SynthesisThe base-catalyzed reaction between benzophenone (1) and butyronitrile (2) gives 2-[hydroxy(diphenyl)methyl]butanenitrile (3). Catalytic hydrogenation reduces the nitrile group to a primary amine giving 1,1-diphenyl-2-ethyl-3-aminopropanol (4).NitrileNitrileOrganic compound with a –C≡N functional groupThe structure of a nitrile: the functional group is highlighted blueIn organic chemistry, a nitrile is any organic compound that has a −C≡Nfunctional group. The name of the compound is composed of a base, which includes the carbon of the −C≡N, suffixed with "nitrile", so for example CH3CH2C≡N is called "propionitrile" (or propanenitrile).AmmoxidationAmmoxidationIn organic chemistry, ammoxidation is a process for the production of nitriles (R−C≡N) using ammonia (NH3) and oxygen (O2). It is sometimes called the SOHIO process, acknowledging that ammoxidation was developed at Standard Oil of Ohio. The usual substrates are alkenes.AmproliumAmproliumAmprolium is the organic compound sold as a coccidiostat used in poultry. It has many International Nonproprietary Names. Uses in coccidiosis treatment in poultryThe drug is a thiamine analogue and blocks the thiamine transporter of Eimeria species. By blocking thiamine uptake it prevents carbohydrate synthesis.Large Molecule HeimatThe Large Molecule Heimat is a dense gas cloud located in the molecular cloud Sagittarius B2. Many species of molecule, including aminoacetonitrile (a molecule related to glycine), ethyl formate, and butyronitrile, have been detected in the Large Molecule Heimat.1-Butanol1-ButanolNames Preferred IUPAC nameButan-1-olOther names n-Butanoln-Butyl alcoholn-Butyl hydroxiden-Propylcarbinoln-Propylmethanol1-HydroxybutaneMethylolpropaneIdentifiers CAS Number71-36-33D model (JSmol)Interactive imageAbbreviations BuOHn-BuOHnBuOHBuOH Beilstein Reference969148 ChEBICHEBI:28885ChEMBLChEMBL14245ChemSpider258DrugBankDB02145ECHA InfoCard100.000.683EC Number200-751-6Gmelin Reference25753 KEGGD03200MeSH1-ButanolPubChemCID263RTECS numberEO1400000UNII8PJ61P6TS3UN number1120 CompTox Dashboard(EPA)DTXSID1021740InChIInChI=1S/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3Key: LRHPLDYGYMQRHN-UHFFFAOYSA-NInChI=1/C4H10O/c1-2-3-4-5/h5H,2-4H2,1H3SMILESOCCCCProperties Chemical formulaC4H10OMolar mass74.123 g·mol Appearance Colourless, refractive liquid Odorbanana-like, harsh, alcoholic and sweet Density0.81 g/cm Melting point−89.8 °C (−129.6 °F; 183.3 K) Boiling point117.7 °C (243.9 °F; 390.8 K) Solubility in water73 g/L at 25 °C Solubilityvery soluble in acetone miscible with ethanol, ethyl etherlog P0.839 Vapor pressure0.58 kPa (20 °C) ILO International Chemical Safety Cards (ICSC) Acidity (pKa) 16.10 Magnetic susceptibility (χ)−56.536·10 cm/mol Refractive index (nD)1.3993 (20 °C) Viscosity2.573 mPa·s (at 25 °C) Dipole moment1.66 D Thermochemistry Std molarentropy(S298)225.7 J/(K·mol) Std enthalpy offormation(ΔfH298)−328(4) kJ/mol Std enthalpy ofcombustion(ΔcH298)−2670(20) kJ/mol Hazards GHS labelling: PictogramsHazard statementsH226, H302, H315, H318, H335, H336Precautionary statementsP210, P233, P240, P241, P242, P243, P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P303+P361+P353, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P370+P378, P403+P233, P403+P235, P405, P501NFPA 704 (fire diamond) 130Flash point35 °C (95 °F; 308 K) Autoignitiontemperature343 °C (649 °F; 616 K) Explosive limits1.45–11.25% Lethal dose or concentration (LD, LC): LD50 (median dose)790 mg/kg (rat, oral) LDLo (lowest published)3484 mg/kg (rabbit, oral)790 mg/kg (rat, oral)1700 mg/kg (dog, oral) LC50 (median concentration)9221 ppm (mammal)8000 ppm (rat, 4 h) NIOSH (US health exposure limits): PEL (Permissible)TWA 100 ppm (300 mg/m) REL (Recommended)C 50 ppm (150 mg/m) [skin] IDLH (Immediate danger)1400 ppm Safety data sheet (SDS) ICSC 0111Related compounds Related compoundsButanethioln-ButylamineDiethyl etherPentaneExcept where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).Nverify ( ?)

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