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Tute Genomics
Tute Genomics is a genomics startup that provides a cloud-based web application for rapid and accurate annotation of human genomic data. Built on the expertise of ANNOVAR, Tute assists researchers in identifying disease genes and biomarkers, and assists clinicians/labs in performing genetic diagnosis. Based in Provo, Utah, Tute was co-founded by Dr. Kai Wang, an assistant professor at the University of Southern California (USC); and Dr. Reid J. Robison, a board-certified psychiatrist with fellowship training in both neurodevelopmental genetics and bioinformatics. The word "tute" means "personal" in the Na’vi language created for the 2009 film ''Avatar'' by Paul Frommer, a linguist and communications professor at the USC Marshall School of Business. Tute Genomics was acquired by PierianDX in 2016. Timeline 2013 * Tute Genomics launched in 2013 and entered the accelerator, BoomStartup. By "demo day" of BoomStartup, Tute had raised their seed round of funding and expanded the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genomics
Genomics is an interdisciplinary field of molecular biology focusing on the structure, function, evolution, mapping, and editing of genomes. A genome is an organism's complete set of DNA, including all of its genes as well as its hierarchical, three-dimensional structural configuration. In contrast to genetics, which refers to the study of ''individual'' genes and their roles in inheritance, genomics aims at the collective characterization and quantification of ''all'' of an organism's genes, their interrelations and influence on the organism. Genes may direct the production of proteins with the assistance of enzymes and messenger molecules. In turn, proteins make up body structures such as organs and tissues as well as control chemical reactions and carry signals between cells. Genomics also involves the sequencing and analysis of genomes through uses of high throughput DNA sequencing and bioinformatics to assemble and analyze the function and structure of entire genomes. Advan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Next-generation Sequencing
Massive parallel sequencing or massively parallel sequencing is any of several high-throughput approaches to DNA sequencing using the concept of massively parallel processing; it is also called next-generation sequencing (NGS) or second-generation sequencing. Some of these technologies emerged between 1993 and 1998 and have been commercially available since 2005. These technologies use miniaturized and parallelized platforms for sequencing of 1 million to 43 billion short reads (50 to 400 bases each) per instrument run. Many NGS platforms differ in engineering configurations and sequencing chemistry. They share the technical paradigm of massive parallel sequencing via spatially separated, clonally amplified DNA templates or single DNA molecules in a flow cell. This design is very different from that of Sanger sequencing—also known as capillary sequencing or first-generation sequencing—which is based on electrophoretic separation of chain-termination products produced in indiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kickstarter
Kickstarter, PBC is an American Benefit corporation, public benefit corporation based in Brooklyn, New York City, that maintains a global crowdfunding platform focused on creativity. The company's stated mission is to "help bring creative projects to life". As of April 2025, Kickstarter has received US$8.71 billion in pledges from 24.1 million backers to fund 277,302 projects, such as films, music, stage shows, comics, journalism, video games, board games, technology, publishing, and food-related projects. People who back Kickstarter projects are offered tangible rewards or experiences in exchange for their pledges. This model traces its roots to subscription model of arts patronage, in which artists would go directly to their audiences to fund their work. History Kickstarter launched on April 28, 2009, by Perry Chen, Yancey Strickler, and Charles Adler. ''The New York Times'' called Kickstarter "the people's National Endowment for the Arts, NEA". ''Time (magazine), Time'' named ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Knome
Knome, Inc. was a human genome interpretation company based in Cambridge, Massachusetts. Launched in 2007, Knome focused on improving quality of life by applying insights gained from the interpretation of human genomes. They helped identify and classify the variants, genes, and gene sets that are likely to govern or underlie a specific disease, tumor, or drug response. Their clients included academic, pharmaceutical and medical researchers. In 2015, it was acquired by Tute Genomics. Technology Knome developed technologies that automated many of the manual tasks involved in interpreting whole human genomes. These technologies were designed to address the informatics and workflow bottlenecks that typically hinder whole genome interpretation. The company's core technology, kGAP, was developed in 2009 and served as the foundation for a number of Knome's products and services including the knoSYS® platform. Products and services For academic, pharmaceutical, and medical research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene By Gene
Gene by Gene is a commercial genetic testing company based in Houston, Texas. The company was owned by Bennett Greenspan and Max Blankfeld, and was the parent company of Family Tree DNA. In January 2021, Gene by Gene was acquired by US based parent company myDNA Inc. Gene by Gene and Australia company myDNA Life Private Ltd. are both subsidiaries of parent company, myDNA Inc. The current Chief Executive Officer of myDNA Inc. is, Dr Lior Rauchberger. History Genealogy by Genetics, Ltd. was formed in 2000 with the creation of FamilyTreeDNA. In September 2012, Greenspan and Blankfeld restructured the company and renamed it Gene by Gene, Ltd. After restructuring, the business comprises four divisions; DNA DTC, DNA Findings, DNA Traits, and Family Tree DNA. FamilyTreeDNA Family Tree DNA was the first commercial company to develop DNA testing for genealogical purposes. It has been operational since April 2000. The Genomics Research Center Family Tree DNA originally partnered with t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peak Ventures
Peak or The Peak may refer to: Basic meanings Geology * Mountain peak ** Pyramidal peak, a mountaintop that has been sculpted by erosion to form a point Mathematics * Peak hour or rush hour, in traffic congestion * Peak (geometry), an (''n''-3)-dimensional element of a polytope * Peak electricity demand or peak usage * Peak-to-peak, the highest (or sometimes the highest and lowest) points on a varying waveform * Peak (pharmacology), the time at which a drug reaches its maximum plasma concentration * Peak experience, psychological term for a euphoric mental state Resource production In terms of resource production, the peak is the moment when the production of a resource reaches a maximum level, after which it declines; in particular see: * Peak oil * Peak car * Peak coal * Peak farmland * Peak gas * Peak minerals * Peak water * Peak wheat * Peak wood Other basic meanings * Visor, a part of a hat, known as a "peak" in British English * Peaked cap Geography * Peak District in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genome
A genome is all the genetic information of an organism. It consists of nucleotide sequences of DNA (or RNA in RNA viruses). The nuclear genome includes protein-coding genes and non-coding genes, other functional regions of the genome such as regulatory sequences (see non-coding DNA), and often a substantial fraction of junk DNA with no evident function. Almost all eukaryotes have mitochondrial DNA, mitochondria and a small mitochondrial genome. Algae and plants also contain chloroplast DNA, chloroplasts with a chloroplast genome. The study of the genome is called genomics. The genomes of many organisms have been Whole-genome sequencing, sequenced and various regions have been annotated. The first genome to be sequenced was that of the virus φX174 in 1977; the first genome sequence of a prokaryote (''Haemophilus influenzae'') was published in 1995; the yeast (''Saccharomyces cerevisiae'') genome was the first eukaryotic genome to be sequenced in 1996. The Human Genome Project ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Exome
The exome is composed of all of the exons within the genome, the sequences which, when transcribed, remain within the mature RNA after introns are removed by RNA splicing. This includes untranslated regions of messenger RNA (mRNA), and coding regions. Exome sequencing has proven to be an efficient method of determining the genetic basis of more than two dozen Mendelian or single gene disorders. Statistics The human exome consists of roughly 233,785 exons, about 80% of which are less than 200 base pairs in length, constituting a total of about 1.1% of the total genome, or about 30 megabases of DNA. Though composing a very small fraction of the genome, mutations in the exome are thought to harbor 85% of mutations that have a large effect on disease. Definition It is important to note that the exome is distinct from the transcriptome, which is all of the transcribed RNA within a cell type. While the exome is constant from cell-type to cell-type, the transcriptome changes ba ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brigham Young University
Brigham Young University (BYU) is a Private education, private research university in Provo, Utah, United States. It was founded in 1875 by religious leader Brigham Young and is the flagship university of the Church Educational System sponsored by the Church of Jesus Christ of Latter-day Saints (LDS Church). BYU offers a variety of academic programs including those in the liberal arts, engineering, agriculture, management, physical and mathematical sciences, nursing, and law. Its undergraduate and graduate programs are organized into 11 colleges and schools at its main Provo campus, with some colleges and divisions defining their own admission standards. The university also administers four satellite campuses, one in BYU Jerusalem Center, Jerusalem, BYU Salt Lake Center, Salt Lake City, BYU Barlow Center, Washington, D.C., and BYU London Study Abroad Centre, London, while its parent organization the Church Educational System (CES) sponsors sister schools in Brigham Young Unive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lineagen
Lineagen, Inc. is a privately held personal genomics and biotechnology company based in Salt Lake City, UT. The company was incorporated in 2006 and collaborated with two leading autism research institutions: the University of Utah and The Children's Hospital of Philadelphia (CHOP), to identify novel genetic variants likely causal of autism spectrum disorder. Lineagen was granted an exclusive commercial license to these novel genetic variants. Notably, the markers from CHOP, published in ''Nature'' and '' PLoS Genetics'', were named by ''TIME'' magazine as one of the top ten medical breakthroughs of 2009. Since 2010, Lineagen provides genetic laboratory services to healthcare providers, which include fluorescence in situ hybridization (FISH), karyotyping A karyotype is the general appearance of the complete set of chromosomes in the cells of a species or in an individual organism, mainly including their sizes, numbers, and shapes. Karyotyping is the process by which a karyotype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
