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Knome
Knome, Inc. was a human genome interpretation company based in Cambridge, Massachusetts. Launched in 2007, Knome focused on improving quality of life by applying insights gained from the interpretation of human genomes. They helped identify and classify the variants, genes, and gene sets that are likely to govern or underlie a specific disease, tumor, or drug response. Their clients included academic, pharmaceutical and medical researchers. In 2015, it was acquired by Tute Genomics. Technology Knome developed technologies that automated many of the manual tasks involved in interpreting whole human genomes. These technologies were designed to address the informatics and workflow bottlenecks that typically hinder whole genome interpretation. The company's core technology, kGAP, was developed in 2009 and served as the foundation for a number of Knome's products and services including the knoSYS® platform. Products and services For academic, pharmaceutical, and medical research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tute Genomics
Tute Genomics is a genomics startup that provides a cloud-based web application for rapid and accurate annotation of human genomic data. Built on the expertise of ANNOVAR, Tute assists researchers in identifying disease genes and biomarkers, and assists clinicians/labs in performing genetic diagnosis. Based in Provo, Utah, Tute was co-founded by Dr. Kai Wang, an assistant professor at the University of Southern California (USC); and Dr. Reid J. Robison, a board-certified psychiatrist with fellowship training in both neurodevelopmental genetics and bioinformatics. The word "tute" means "personal" in the Na’vi language created for the 2009 film ''Avatar'' by Paul Frommer, a linguist and communications professor at the USC Marshall School of Business. Tute Genomics was acquired by PierianDX in 2016. Timeline 2013 * Tute Genomics launched in 2013 and entered the accelerator, BoomStartup. By "demo day" of BoomStartup, Tute had raised their seed round of funding and expanded the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ozzy Osbourne
John Michael "Ozzy" Osbourne (born 3 December 1948) is an English singer, songwriter, and media personality. He rose to prominence during the 1970s as the lead singer of the heavy metal music, heavy metal band Black Sabbath, during which period he adopted the nickname "Prince of Darkness". Osbourne became a founding member of Black Sabbath in 1968, providing lead vocals from Black Sabbath (album), their self-titled debut album in 1970 to ''Never Say Die!'' in 1978. The band was highly influential in the development of heavy metal music, in particular their critically acclaimed releases ''Paranoid (album), Paranoid'', ''Master of Reality'', and ''Sabbath Bloody Sabbath''. Osbourne was fired from Black Sabbath in 1979 due to problems with alcohol and other drugs. He then began a successful solo career with ''Blizzard of Ozz'' in 1980 and has released Ozzy Osbourne discography, 13 studio albums, the first seven of which received multi-platinum certifications in the US. He has si ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Henry Louis Gates Jr
Henry Louis Gates Jr. (born September 16, 1950), popularly known by his childhood nickname "Skip", is an American literary critic, professor, historian, and filmmaker who serves as the Alphonse Fletcher University Professor and the director of the Hutchins Center for African and African American Research at Harvard University. He is a trustee of the Gilder Lehrman Institute of American History. He rediscovered the earliest known African-American novels and has published extensively on the recognition of African-American literature as part of the Western canon. In addition to producing and hosting previous series on the history and genealogy of prominent American figures, since 2012, Gates has been host of the television series ''Finding Your Roots'' on PBS. The series combines the work of expert researchers in genealogy, history, and historical research in genetics to tell guests about the lives and histories of their ancestors. Early life and education Gates was born on Septe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whole Genome Sequencing
Whole genome sequencing (WGS), also known as full genome sequencing or just genome sequencing, is the process of determining the entirety of the DNA sequence of an organism's genome at a single time. This entails sequencing all of an organism's chromosomal DNA as well as DNA contained in the mitochondrial DNA, mitochondria and, for plants, in the chloroplast. Whole genome sequencing has largely been used as a research tool, but was being introduced to clinics in 2014. In the future of personalized medicine, whole genome sequence data may be an important tool to guide therapeutic intervention. The tool of DNA sequencing, gene sequencing at Single-nucleotide polymorphism, SNP level is also used to pinpoint functional variants from association studies and improve the knowledge available to researchers interested in evolutionary biology, and hence may lay the foundation for predicting disease susceptibility and drug response. Whole genome sequencing should not be confused with DNA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Faces Of America
''Faces of America'' is a four-part American television series hosted by Professor Henry Louis Gates Jr.. The series originally aired February 10 to March 3, 2010 from 8–9 p.m. ET.PBS WNET: About Faces of America Accessed online 7 March 2010. In , this program aired on SBS One each Sunday at 7:30pm from 9 -30 January 2011. About It uses genealogical research and genetics to find the family history of 12 Americans: Elizabeth Alexander,[...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Privately Held Company
A privately held company (or simply a private company) is a company whose Stock, shares and related rights or obligations are not offered for public subscription or publicly negotiated in their respective listed markets. Instead, the Private equity, company's stock is offered, owned, traded or exchanged privately, also known as "over-the-counter (finance), over-the-counter". Related terms are unlisted organisation, unquoted company and private equity. Private companies are often less well-known than their public company, publicly traded counterparts but still have major importance in the world's economy. For example, in 2008, the 441 list of largest private non-governmental companies by revenue, largest private companies in the United States accounted for $1.8 trillion in revenues and employed 6.2 million people, according to ''Forbes''. In general, all companies that are not owned by the government are classified as private enterprises. This definition encompasses both publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of British Columbia
The University of British Columbia (UBC) is a Public university, public research university with campuses near University of British Columbia Vancouver, Vancouver and University of British Columbia Okanagan, Kelowna, in British Columbia, Canada. With an annual research budget of $893million, UBC funds 9,992 projects annually in various fields of study within the industrial sector, as well as governmental and non-governmental organizations. The Vancouver campus is situated on the University of British Columbia Vancouver, Point Grey campus lands, an unincorporated area next to the City of Vancouver and the University Endowment Lands.Municipalities Enabling and Validating Act (No. 3)', S.B.C. 2001, c. 44. The university is located west of Downtown Vancouver. UBC is also home to TRIUMF, Canada's national Particle physics, particle and nuclear physics laboratory, which boasts the world's largest cyclotron. In addition to the Peter Wall Institute for Advanced Studies and the Stuart B ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sharon Osbourne
Sharon Rachel Osbourne (; born 9 October 1952) is an English-American television personality, music manager, and author. She is married to heavy metal singer Ozzy Osbourne and came to prominence while appearing on '' The Osbournes'' (2002–2005), a reality television show that aired on MTV, which followed her family's daily life. Osbourne later became a judge on television talent competition shows, including ''The X Factor'' (2004–2007, 2013, 2016–2017) and '' America's Got Talent'' (2007–2012). Osbourne is credited with reviving her husband's heavy metal career by founding the summer Ozzfest tour, which was held almost annually between 1996 and 2018. In light of her success managing her husband, she branched out into managing other acts, such as Gary Moore, Motörhead, Lita Ford, and The Smashing Pumpkins, through her company Sharon Osbourne Management. From 2003 to 2004, Osbourne hosted her own talk show '' The Sharon Osbourne Show,'' which was syndicated to var ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nova (American TV Series)
''Nova'' (stylized as ''NOVΛ'') is an American popular science television program produced by WGBH-TV, WGBH in Boston, Massachusetts, since 1974. It is broadcast on PBS in the United States, and in more than 100 other countries. The program has won many major television awards. ''Nova'' often includes interviews with scientists doing research in the subject areas covered and occasionally includes footage of a particular discovery. Some episodes have focused on the history of science. Examples of topics covered include the following: Colditz Castle, the Drake equation, elementary particles, the 1980 eruption of Mount St. Helens, Fermat's Last Theorem, the AIDS epidemic, global warming, Silicon carbide, moissanite, Project Azorian, Project Jennifer, storm chasing, German submarine U-869, Unterseeboot 869, Vinland map, Vinland, Tarim mummies, and the COVID-19 pandemic. The ''Nova'' programs have been praised for their pacing, writing, and editing. Websites that accompany the se ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins School Of Medicine
The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Established in 1893 following the construction of the Johns Hopkins Hospital, the school is known for being a center of biomedical research and innovation, and is routinely ranked as one of the top medical schools in the United States. The School of Medicine is located in Baltimore, Maryland, where it shares a campus in East Baltimore with the School of Nursing, Bloomberg School of Public Health, and Johns Hopkins Hospital, the school's primary teaching hospital. As part of the larger Johns Hopkins Medicine health system, the school is also affiliated with numerous regional hospitals and medical centers including the Johns Hopkins Bayview Medical Center, Johns Hopkins Howard County Medical Center, Suburban Hospital in Montgomery County, Sibley Memorial Hospital in Washington, D.C. History Before his death in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parkinson's Disease
Parkinson's disease (PD), or simply Parkinson's, is a neurodegenerative disease primarily of the central nervous system, affecting both motor system, motor and non-motor systems. Symptoms typically develop gradually and non-motor issues become more prevalent as the disease progresses. The motor symptoms are collectively called parkinsonism and include tremors, bradykinesia, spasticity, rigidity as well as postural instability (i.e., difficulty maintaining balance). Non-motor symptoms develop later in the disease and include behavior change (individual), behavioral changes or mental disorder, neuropsychiatric problems such as sleep abnormalities, psychosis, anosmia, and mood swings. Most Parkinson's disease cases are idiopathic disease, idiopathic, though contributing factors have been identified. Pathophysiology involves progressive nerve cell death, degeneration of nerve cells in the substantia nigra, a midbrain region that provides dopamine to the basal ganglia, a system invo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
