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Raissa Nitabuch
Raissa Nitabuch (; born 1859) was a Russian Pathology, pathologist who is known for her histological studies of the human placenta. The layer of fibrin that was thought to separate the uterine decidua from the fetoplacental trophoblast after birth was named the Nitabuch layer or Nitabuch membrane, thus becoming the only woman whose name is "affiliated with a macroscopic anatomical structure." She was also the first to describe the spiral arteries which connect the uterine and placental blood flow during pregnancy, providing the developing fetus with oxygen and nutrients. Part of a group of Russian women who studied medicine at the University of Zurich, she then completed her doctoral thesis in 1887 at the Institute of Anatomy in Bern under the supervision of pathologist Theodor Langhans. Her identification of the spiral arteries challenged the predominant scientific consensus of the day, which held that there was no interconnection between the uterine circulation and the intervill ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Zurich
The University of Zurich (UZH, ) is a public university, public research university in Zurich, Switzerland. It is the largest university in Switzerland, with its 28,000 enrolled students. It was founded in 1833 from the existing colleges of theology, law, medicine which go back to 1525, and a new Faculty (division), faculty of philosophy. Currently, the university has seven faculties: Philosophy, Medicine, Human Medicine, Economic Sciences, Law, Mathematics and Natural Sciences, Theology and Veterinary Medicine. The university offers the widest range of subjects and courses of any Swiss higher education institution. History The University of Zurich was founded on April 29, 1833, when the existing colleges of theology, the Carolinum, Zurich, ''Carolinum'' founded by Huldrych Zwingli in 1525, law and medicine were merged with a new faculty of Philosophy. It was the first university in Europe to be founded by the state rather than a monarch or church. Its Latin name is reminiscen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bern
Bern (), or Berne (), ; ; ; . is the ''de facto'' Capital city, capital of Switzerland, referred to as the "federal city".; ; ; . According to the Swiss constitution, the Swiss Confederation intentionally has no "capital", but Bern has governmental institutions such as the Federal Assembly (Switzerland), Federal Assembly and Federal Council (Switzerland), Federal Council. However, the Federal Supreme Court of Switzerland, Federal Supreme Court is in Lausanne, the Federal Criminal Court of Switzerland, Federal Criminal Court is in Bellinzona and the Federal Administrative Court (Switzerland), Federal Administrative Court and the Federal Patent Court (Switzerland), Federal Patent Court are in St. Gallen, exemplifying the federal nature of the Confederation. With a population of about 146,000 (), Bern is the List of cities in Switzerland, fifth-most populous city in Switzerland, behind Zürich, Geneva, Basel and Lausanne. The Bern agglomeration, which includes 36 municipalities ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathology
Pathology is the study of disease. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area that includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue (biology), tissue and human cell samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be "Pathophysiology, pathophysiologies"). The suffix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomyopathy) and psych ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Placenta
The placenta (: placentas or placentae) is a temporary embryonic and later fetal organ that begins developing from the blastocyst shortly after implantation. It plays critical roles in facilitating nutrient, gas, and waste exchange between the physically separate maternal and fetal circulations, and is an important endocrine organ, producing hormones that regulate both maternal and fetal physiology during pregnancy. The placenta connects to the fetus via the umbilical cord, and on the opposite aspect to the maternal uterus in a species-dependent manner. In humans, a thin layer of maternal decidual ( endometrial) tissue comes away with the placenta when it is expelled from the uterus following birth (sometimes incorrectly referred to as the 'maternal part' of the placenta). Placentas are a defining characteristic of placental mammals, but are also found in marsupials and some non-mammals with varying levels of development. Mammalian placentas probably first evolved abou ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fibrin
Fibrin (also called Factor Ia) is a fibrous protein, fibrous, non-globular protein involved in the Coagulation, clotting of blood. It is formed by the action of the protease thrombin on fibrinogen, which causes it to polymerization, polymerize. The polymerized fibrin, together with platelets, forms a hemostasis, hemostatic plug or clot over a wound site. When the lining of a blood vessel is broken, platelets are attracted, forming a platelet plug. These platelets have thrombin receptors on their surfaces that bind serum thrombin molecules, which in turn convert soluble fibrinogen in the serum into fibrin at the wound site. Fibrin forms long strands of tough insoluble protein that are bound to the platelets. Factor XIII completes the cross-linking of fibrin so that it hardens and contracts. The cross-linked fibrin forms a mesh atop the platelet plug that completes the clot. Fibrin was discovered by Marcello Malpighi in 1666. Role in disease Excessive generation of fibrin due ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Decidua
The decidua is the modified mucosal lining of the uterus (that is, modified endometrium) that forms every month, in preparation for pregnancy. It is shed off each month when there is no fertilized egg to support. The decidua is under the influence of progesterone. Endometrial cells become highly characteristic. The decidua forms the maternal part of the placenta and remains for the duration of the pregnancy. After birth the decidua is shed together with the placenta. Structure The part of the decidua that interacts with the trophoblast is the ''decidua basalis'' (also called ''decidua placentalis''), while the ''decidua capsularis'' grows over the embryo on the luminal side, enclosing it into the endometrium. The remainder of the decidua is termed the ''decidua parietalis'' or ''decidua vera'', and it will fuse with the decidua capsularis by the fourth month of gestation. Three morphologically distinct layers of the decidua basalis can then be described: * Compact outer layer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Trophoblast
The trophoblast (from Greek language, Greek : to feed; and : germinator) is the outer layer of cells of the blastocyst. Trophoblasts are present four days after Human fertilization, fertilization in humans. They provide nutrients to the embryo and develop into a large part of the placenta. They form during the first stage of pregnancy and are the first cells to Cellular differentiation, differentiate from the fertilized Ovum, egg to become extraembryonic structures that do not directly contribute to the embryo. After blastulation, the trophoblast is contiguous with the ectoderm of the embryo and is referred to as the trophectoderm. After the first differentiation, the cells in the human embryo lose their Cell potency#Totipotency, totipotency because they can no longer form a trophoblast. They become Cell potency#Pluripotency, pluripotent stem cells. Structure The trophoblast proliferates and differentiates into two cell layers at approximately six days after fertilization for ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Birth
Birth is the act or process of bearing or bringing forth offspring, also referred to in technical contexts as parturition. In mammals, the process is initiated by hormones which cause the muscular walls of the uterus to contract, expelling the fetus at a developmental stage when it is ready to feed and breathe. In some species, the offspring is precocial and can move around almost immediately after birth but in others, it is altricial and completely dependent on parenting. In marsupials, the fetus is born at a very immature stage after a short gestation and develops further in its mother's womb Pouch (marsupial), pouch. It is not only mammals that give birth. Some reptiles, amphibians, fish and invertebrates carry their developing young inside them. Some of these are Ovoviviparity, ovoviviparous, with the eggs being hatched inside the mother's body, and others are Viviparity, viviparous, with the embryo developing inside their body, as in the case of mammals. Human childbirth ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spiral Arteries
Spiral arteries are small arteries which temporarily supply blood to the endometrium of the uterus during the luteal phase of the menstrual cycle. In histology, identifying the presence of these arteries is one of the most useful techniques in identifying the phase of the cycle. The spiral arteries are converted for uteroplacental blood flow during pregnancy, involving: * Loss of smooth muscle and elastic lamina from the vessel wall. * 5-10 fold dilation at the mouth of the vessel. Failure of the physiological conversion of the spiral arteries can cause a number of complications, including intrauterine growth restriction and pre-eclampsia Pre-eclampsia is a multi-system disorder specific to pregnancy, characterized by the new onset of hypertension, high blood pressure and often a significant amount of proteinuria, protein in the urine or by the new onset of high blood pressure a .... References Arteries of the abdomen articles {{circulatory-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Theodor Langhans
Theodor Langhans (28 September 1839 – 22 October 1915) was a German pathologist who was a native of Usingen, Duchy of Nassau. He studied medicine at the University of Heidelberg, and at the University of Göttingen under Friedrich Gustav Jakob Henle (1809–1885), at Berlin under Rudolf Virchow (1821–1902) and in Würzburg, where he became an assistant to Friedrich Daniel von Recklinghausen (1833–1910). In 1867 he became a lecturer at the University of Marburg, and in 1872 became a full professor of pathology at the University of Giessen, where he succeeded Ludwig Franz Alexander Winther (1812–1871). From 1872 until 1912, Langhans was a professor of pathological anatomy at the University of Bern, where one of his assistants was surgeon Fritz de Quervain (1868–1940). He also worked with Serafina Schachova on kidney anatomy research using a canine model of induced nephritis. Langhans is remembered for his discovery of multi-nucleated giant cells that are found in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Women Pathologists
A woman is an adult female human. Before adulthood, a female child or adolescent is referred to as a girl. Typically, women are of the female sex and inherit a pair of X chromosomes, one from each parent, and women with functional uteruses are capable of pregnancy and giving birth from puberty until menopause. More generally, sex differentiation of the female fetus is governed by the lack of a present, or functioning, '' SRY'' gene on either one of the respective sex chromosomes. Female anatomy is distinguished from male anatomy by the female reproductive system, which includes the ovaries, fallopian tubes, uterus, vagina, and vulva. An adult woman generally has a wider pelvis, broader hips, and larger breasts than an adult man. These characteristics facilitate childbirth and breastfeeding. Women typically have less facial and other body hair, have a higher body fat composition, and are on average shorter and less muscular than men. Throughout human history, traditional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Physicians From The Russian Empire
A physician, medical practitioner (British English), medical doctor, or simply doctor is a health professional who practices medicine, which is concerned with promoting, maintaining or restoring health through the study, diagnosis, prognosis and treatment of disease, injury, and other physical and mental impairments. Physicians may focus their practice on certain disease categories, types of patients, and methods of treatment—known as specialities—or they may assume responsibility for the provision of continuing and comprehensive medical care to individuals, families, and communities—known as general practice. Medical practice properly requires both a detailed knowledge of the academic disciplines, such as anatomy and physiology, underlying diseases, and their treatment, which is the science of medicine, and a decent competence in its applied practice, which is the art or craft of the profession. Both the role of the physician and the meaning of the word itself vary ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
