Pliva
Pliva d.o.o. is a pharmaceutical company based in Zagreb, Croatia that primarily manufactures and sells generic drugs. It is a subsidiary of Teva Pharmaceuticals. Pliva is one of the world's largest producers of Generic drug, generic Adderall. History The company was founded in 1921. A team of Pliva's researchers, Gabrijela Kobrehel, Gorjana Radobolja-Lazarevski and Zrinka Tamburašev led by Dr. Slobodan Đokić, discovered azithromycin in 1980. In June 2002, the company acquired Sidmak for $152.9 million. Also in June 2002, Zeljko Peric, the chief financial officer of the company, resigned. In May 2004, the company received approval from the Food and Drug Administration to sell trospium chloride. In June 2005, the company received approval to sell a generic version of erythropoietin in Croatia. In November 2005, the company received approval from the Food and Drug Administration to sell a generic version of Azithromycin, Citalopram, and Ondansetron. In October 2006, Bar ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Azithromycin
Azithromycin, sold under the brand names Zithromax (in oral form) and Azasite (as an eye drop), is an antibiotic medication used for the treatment of several bacterial infections. This includes otitis media, middle ear infections, strep throat, pneumonia, traveler's diarrhea, Sexually transmitted infection, STI and certain other gastroenteritis, intestinal infections. Along with other medications, it may also be used for malaria. It is Drug administration, administered by mouth, intravenously, into a vein, or into the eye drops, eye. Common side effects include nausea, vomiting, diarrhea and upset stomach. An allergic reaction, such as anaphylaxis, or a type of diarrhea caused by Clostridioides difficile infection, ''Clostridioides difficile'' is possible. Azithromycin causes drug-induced QT prolongation, QT prolongation that may cause life-threatening arrhythmias such as torsades de pointes. While some studies claim that no harm has been found with use during pregnancy, more ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Trospium Chloride
Trospium chloride is a muscarinic antagonist used to treat overactive bladder. It has side effects typical of this class of drugs, namely dry mouth, stomach upset, and constipation; these side effects cause problems with people taking their medicine as directed. However it doesn't cause central nervous system side effects like some other muscarinic antagonists. Chemically it is a quaternary ammonium cation which causes it to stay in periphery rather than crossing the blood–brain barrier. It works by causing the smooth muscle in the bladder to relax. It was patented in 1966 and approved for medical use in 1974. It was first approved in the US in 2004, and an extended release version was brought to market in 2007. It became generic in the EU in 2009, and the first extended-release generic was approved in the US in 2012. Medical uses Trospium chloride is used for the treatment of overactive bladder with symptoms of urge incontinence and frequent urination. It should not be ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Barr Pharmaceuticals
Barr Pharmaceuticals was an American specialty and generic drug manufacturer with operations in 30 countries. Approximately 75% of the company's revenues came from the sale of generic drugs, including 18% of sales which were from the sale of oral contraceptive pills. It was acquired by Teva Pharmaceutical Industries in 2008 for an estimated $7.46 billion . History Barr Laboratories Inc. was founded in New York in 1970 by Edwin A. Cohen. Starting in 1991 Barr Laboratories was involved in a scandal stemming from their violation of GMP regulations concerning handling of out-of-specification (OOS) test results. In 1993 Barr Labs lost a lawsuit stemming from these findings, resulting in new industry interpretations of FDA regulations regarding out of specification test results. In 1993, Bruce L. Downey joined the company as its president and in 1994, he became chairman and chief executive officer of the company. In 1993, the company settled a patent infringement case and began di ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Zrinka Tamburašev
Zrinka Tamburašev was a Croatian scientist known for her work in the development of antibiotics such as oxytetracycline and azithromycin. Early life Tamburašev was born in Sisak, Kingdom of Yugoslavia, in 1921. She graduated in 1948 from the Chemical-Technological Department of the Technical Faculty in Zagreb and earned her doctorate in 1965. Career She joined the research institute of the pharmaceutical company Pliva, PLIVA in 1957, where she made several discoveries and patents in departments of microbiology, biochemistry, and biotechnology. While at PLIVA she led the group for semisynthetic macrolides from 1972 to 1974, and in 1974 she was named the head of the natural products department. In the mid-1960s, she worked with Slobodan Đokić on erythromycin A derivatives and on sulfonamide derivatives of erythromycylamine, with the idea of combining the properties of erythromycin and sulfonamides. She began work on the synthesis of individual phases for the preparation of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Teva Pharmaceuticals
Teva Pharmaceutical Industries Ltd. (also known as Teva Pharmaceuticals) is an Israeli multinational Pharmaceutical industry, pharmaceutical company. Teva specializes primarily in generic drugs, but other business interests include branded-drugs, active pharmaceutical ingredients (APIs) and, to a lesser extent, contract manufacturing services and an out-licensing platform. Teva's primary branded products include Austedo (deutetrabenazine) which is used for the treatment of chorea associated with Huntington's disease and tardive dyskinesia; and Ajovy (fremanezumab), used for the preventive treatment of migraine in adults. Additional branded drugs sold by Teva include Copaxone, Bendeka and Treanda, all of which are primarily sold in the United States. Teva is listed on the Tel Aviv Stock Exchange and the New York Stock Exchange. Its manufacturing facilities are located in Israel, North America, Europe, Australia, and South America. The company is a member of the Pharmaceutical ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Croatian Brands
The following products could be described as hallmarks of Croatian trade. Croatiastreet awards its own quality seal () to the best Croatian products every year. Croatian Chamber of Economy confers the () seal to Croatian products and services that undergo rigorous assessments to be recognised as a result of innovation, research and development by Croatian people and enterprises. Wines Croatian wines (''vino'', pl. ''vina'' in Croatian) have gained in quality, but are still largely unknown to the world wine market. It is a matter of the developing Croatian economy to make these wines more popular in the world, and it is up to Croatian wine producers to start large-scale production for international markets. White wines * Bogdanuša * Debit (grape) * Graševina * Grk Bijeli * Kujundžuša – from the region of Imotski * Malvasia Dubrovačka * Malvazija Istarska * Pošip * Pušipel * Traminac * Vugava – from Vis Island * Žlahtina – from the Island of Krk Red wines ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Teva Active Pharmaceutical Ingredients (TAPI)
Teva API is an international pharmaceutical company headquartered in Israel. Teva API is a stand-alone business unit of Teva Pharmaceutical Industries limited, the largest generic drug manufacturer in the world and one of the 15 largest pharmaceutical companies worldwide. On top of supplying a major share of Teva's own needs, the Teva API division is an active competitor in world markets, investing both in the development of new products, manufacturing processes and in the upgrading of production facilities. In 2014, Teva API's sales to third parties totaled $724 million. In recent years growth occurred in all of Teva API's principal geographical markets: North America, Europe and International. History At the heart of the API division is the Israel-based Teva-Tech, formerly known as the Asia and Plantex plants which manufacture, develop and market raw materials for pharmaceuticals. Acquisitions Teva api has grown by acquiring manufacturing and development facilities aroun ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Pharmaceutical Companies Established In 1921
Medication (also called medicament, medicine, pharmaceutical drug, medicinal product, medicinal drug or simply drug) is a drug used to medical diagnosis, diagnose, cure, treat, or preventive medicine, prevent disease. Drug therapy (pharmacotherapy) is an important part of the medicine, medical field and relies on the science of pharmacology for continual advancement and on pharmacy for appropriate management. Drugs are Drug class, classified in many ways. One of the key divisions is by level of controlled substance, control, which distinguishes prescription drugs (those that a pharmacist dispenses only on the medical prescription) from over-the-counter drugs (those that consumers can order for themselves). Medicines may be classified by mode of action, route of administration, biological system affected, or therapeutic effects. The World Health Organization keeps a list of essential medicines. Drug discovery and drug development are complex and expensive endeavors undertake ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |
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Manufacturing Companies Based In Zagreb
Manufacturing is the creation or production of goods with the help of equipment, labor, machines, tools, and chemical or biological processing or formulation. It is the essence of the secondary sector of the economy. The term may refer to a range of human activity, from handicraft to high-tech, but it is most commonly applied to industrial design, in which raw materials from the primary sector are transformed into finished goods on a large scale. Such goods may be sold to other manufacturers for the production of other more complex products (such as aircraft, household appliances, furniture, sports equipment or automobiles), or distributed via the tertiary industry to end users and consumers (usually through wholesalers, who in turn sell to retailers, who then sell them to individual customers). Manufacturing engineering is the field of engineering that designs and optimizes the manufacturing process, or the steps through which raw materials are transformed into a final prod ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   [Amazon] |