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MetaboLights
MetaboLights is a data repository founded in 2012 for cross-species and cross-platform Metabolomics, metabolomic studies that provides primary research data and meta data for metabolomic studies as well as a knowledge base for properties of individual metabolites. The database is maintained by the European Bioinformatics Institute, European Bioinformatics Institute (EMBL-EBI) and the development is funded by Biotechnology and Biological Sciences Research Council (BBSRC). As of July 2018, the MetaboLights browse functionality consists of 383 studies, two analytical platforms, NMR spectroscopy and mass spectrometry. Semantic annotation is based on various ontologies and controlled vocabularies, including the BRENDA tissue ontology and the National Center for Biotechnology Information, NCBI taxonomy. The metabolite structure data is linked to chemical databases, including ChemSpider, PubChem, and ChEBI. Links to metabolite databases, however, seem to be missing. MetaboLights consist ...
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ChEBI
Chemical Entities of Biological Interest, also known as ChEBI, is a chemical database and ontology of molecular entities focused on "small" chemical compounds, that is part of the Open Biomedical Ontologies (OBO) effort at the European Bioinformatics Institute (EBI). The term "molecular entity" refers to any "constitutionally or isotopically distinct atom, molecule, ion, ion pair, radical, radical ion, complex, conformer, etc., identifiable as a separately distinguishable entity". The molecular entities in question are either products of nature or synthetic products which have potential bioactivity. Molecules directly encoded by the genome, such as nucleic acids, proteins and peptides derived from proteins by proteolytic cleavage, are not as a rule included in ChEBI. ChEBI uses nomenclature, symbolism and terminology endorsed by the International Union of Pure and Applied Chemistry (IUPAC) and nomenclature committee of the International Union of Biochemistry and Molecular Bio ...
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Metabolomic Databases
Metabolomics is the scientific study of chemical processes involving metabolites, the small molecule substrates, intermediates, and products of cell metabolism. Specifically, metabolomics is the "systematic study of the unique chemical fingerprints that specific cellular processes leave behind", the study of their small-molecule metabolite profiles. The metabolome represents the complete set of metabolites in a biological cell, tissue, organ, or organism, which are the end products of cellular processes. Messenger RNA (mRNA), gene expression data, and proteomics, proteomic analyses reveal the set of gene products being produced in the cell, data that represents one aspect of cellular function. Conversely, metabolic profiling can give an instantaneous snapshot of the physiology of that cell, and thus, metabolomics provides a direct "functional readout of the physiological state" of an organism. There are indeed quantifiable correlations between the metabolome and the other cellular ...
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Protocol
Protocol may refer to: Sociology and politics * Protocol (politics) Protocol originally (in Late Middle English, c. 15th century) meant the minutes or logbook taken at a meeting, upon which an agreement was based. The term now commonly refers to an agreement resulting from a meeting, or more generally to any estab ..., a formal agreement between nation states * Protocol (diplomacy), the etiquette of diplomacy and affairs of state * Etiquette, a code of personal behavior Science and technology * Protocol (science), a predefined written procedural method of conducting experiments * Medical protocol (other) Computing * Protocol (object-oriented programming), a common means for unrelated objects to communicate with each other (sometimes also called ''interfaces'') * Communication protocol, a defined set of rules and regulations that determine how data is transmitted in telecommunications and computer networking * Cryptographic protocol, a protocol for encrypting data Music ...
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Scientific Data (journal)
''Scientific Data'' is a peer-reviewed open access scientific journal published by Nature Research since 2014. It focuses on descriptions of data sets relevant to the natural sciences, medicine, engineering and social sciences, which are provided as machine-readable data, complemented with a human oriented narrative. The journal was not the first to publish data papers, but is one of a few journals whose content consists primarily of data papers. The journal is abstracted and indexed by Index Medicus/MEDLINE/PubMed PubMed is an openly accessible, free database which includes primarily the MEDLINE database of references and abstracts on life sciences and biomedical topics. The United States National Library of Medicine (NLM) at the National Institute .... References External links * Nature Research academic journals Creative Commons Attribution-licensed journals Academic journals established in 2014 Multidisciplinary scientific journals English-language jo ...
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Nature Publishing Group
Nature Portfolio (formerly known as Nature Publishing Group and Nature Research) is a division of the international scientific publishing company Springer Nature that publishes academic journals, magazines, online databases, and services in science and medicine. Nature Research's flagship publication is ''Nature'', a weekly multidisciplinary journal first published in 1869. It also publishes the ''Nature-''titled research journals, ''Nature Reviews'' journals (since 2000), society-owned academic journals, and a range of open access journals, including ''Scientific Reports'' and ''Nature Communications''. Springer Nature also publishes ''Scientific American'' in 16 languages, a magazine intended for the general public. In 2013, prior to the merger with Springer and the creation of Springer Nature, Nature Publishing Group's owner, Holtzbrinck Publishing Group, bought a controlling stake in Frontiers. Before Springer Nature was formed in 2015, Nature Research (as the Nature Publi ...
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EMBO Journal
''The EMBO Journal'' is a semi-monthly peer-reviewed scientific journal focusing on full-length papers describing original research of general interest in molecular biology and related areas. The editor-in-chief is Facundo D. Batista (Harvard Medical School). History The journal was established in 1982 and was published by Nature Publishing Group on behalf of the European Molecular Biology Organization until the launch of EMBO Press in 2013. Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2023 impact factor of 9.4. See also *''EMBO Reports ''EMBO Reports'' is a peer-reviewed scientific journal covering research related to biology at a molecular level. It publishes primary research papers, reviews, and essays and opinion. It also features commentaries on the social impact of adva ...'' *'' Molecular Systems Biology'' References External links * * (1986–2003 issues from microfilm) Mo ...
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Scientific Journal
In academic publishing, a scientific journal is a periodical publication designed to further the progress of science by disseminating new research findings to the scientific community. These journals serve as a platform for researchers, scholars, and scientists to share their latest discoveries, insights, and methodologies across a multitude of scientific disciplines. Unlike professional or trade magazines, the articles are mostly written by scientists rather than staff writers employed by the journal. Scientific journals are characterized by their rigorous peer review process, which aims to ensure the validity, reliability, and quality of the published content. In peer review, submitted articles are reviewed by active scientists (peers) to ensure scientific rigor. With origins dating back to the 17th century, the publication of scientific journals has evolved significantly, advancing scientific knowledge, fostering academic discourse, and facilitating collaboration within ...
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Metadata
Metadata (or metainformation) is "data that provides information about other data", but not the content of the data itself, such as the text of a message or the image itself. There are many distinct types of metadata, including: * Descriptive metadata – the descriptive information about a resource. It is used for discovery and identification. It includes elements such as title, abstract, author, and keywords. * Structural metadata – metadata about containers of data and indicates how compound objects are put together, for example, how pages are ordered to form chapters. It describes the types, versions, relationships, and other characteristics of digital materials. * Administrative metadata – the information to help manage a resource, like resource type, and permissions, and when and how it was created. * Reference metadata – the information about the contents and quality of Statistical data type, statistical data. * Statistical metadata – also called process data, may ...
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Scientific Method
The scientific method is an Empirical evidence, empirical method for acquiring knowledge that has been referred to while doing science since at least the 17th century. Historically, it was developed through the centuries from the ancient and medieval world. The scientific method involves careful observation coupled with rigorous skepticism, because Philosophy of science#Observation inseparable from theory, cognitive assumptions can distort the interpretation of the Perception#Process and terminology, observation. Scientific inquiry includes creating a testable hypothesis through inductive reasoning, testing it through experiments and statistical analysis, and adjusting or discarding the hypothesis based on the results. Although procedures vary across Branches of science, fields, the underlying #Process, process is often similar. In more detail: the scientific method involves making conjectures (hypothetical explanations), predicting the logical consequences of hypothesis, then ...
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Data Sharing
Data sharing is the practice of making data used for scholarly research available to other investigators. Many funding agencies, institutions, and publication venues have policies regarding data sharing because transparency and openness are considered by many to be part of the scientific method. A number of funding agencies and science journals require authors of peer-reviewed papers to share any supplemental information (raw data, statistical methods or source code) necessary to understand, develop or reproduce published research. A great deal of scientific research is not subject to data sharing requirements, and many of these policies have liberal exceptions. In the absence of any binding requirement, data sharing is at the discretion of the scientists themselves. In addition, in certain situations governments and institutions prohibit or severely limit data sharing to protect proprietary interests, national security, and subject/patient/victim confidentiality. Data sharing may ...
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