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Lübeck Disaster
From 1929 to 1933, 251 infants in Lübeck, northern Germany, were given three doses of the oral BCG vaccine against tuberculosis, which was accidentally contaminated with the bacteria responsible for the disease. 173 later developed signs of the illness and 77 died. It was initially thought that of the 77, only 72 died of TB causes. Contaminated vaccine This vaccine itself was initially blamed, until an inquiry headed by of the Robert Koch Institute and Ludwig Lange of the Ministry of Health identified contamination as the cause. The event later became known as the Lübeck disaster, or in German, the ''Lübecker Impfunglück'' (Lübeck vaccine disaster). Major scientific journals worldwide commented on the disaster and subsequent trials of the medical staff, such as ''The Lancet'' and the ''Journal of the American Medical Association''. Legal consequences On 6 February 1932, , the head of the general hospital in Lübeck, was found guilty of negligent homicide and neglige ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lübeck
Lübeck (; or ; Latin: ), officially the Hanseatic League, Hanseatic City of Lübeck (), is a city in Northern Germany. With around 220,000 inhabitants, it is the second-largest city on the German Baltic Sea, Baltic coast and the second-largest city in the state of Schleswig-Holstein, after its capital of Kiel. It is the List of cities in Germany by population, 36th-largest city in Germany. The city lies in the Holsatian part of Schleswig-Holstein, on the mouth of the Trave, which flows into the Bay of Lübeck in the borough of Travemünde, and on the Trave's tributary Wakenitz. The island with the historic old town and the districts north of the Trave are also located in the historical region of Wagria. Lübeck is the southwesternmost city on the Baltic Sea, and the closest point of access to the Baltic from Hamburg. The city lies in the Northern Low Saxon, Holsatian dialect area of Low German. The name ''Lübeck'' ultimately stems from the Slavic languages, Slavic root (' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intradermal
Intradermal injection (also intracutaneous or intradermic, abbreviated as ID) is a shallow or superficial injection of a substance into the dermis, which is located between the epidermis and the hypodermis. For certain substances, administration via an ID route can result in a faster systemic uptake compared with subcutaneous injections, leading to a stronger immune response to vaccinations, immunology and novel cancer treatments, and faster drug uptake. Additionally, since administration is closer to the surface of the skin, the body's reaction to substances is more easily visible. However, due to complexity of the procedure compared to subcutaneous injection and intramuscular injection, administration via ID is relatively rare, and is only used for tuberculosis and allergy tests, monkeypox vaccination, and certain therapies. Vaccine dose sparing For vaccination many clinical studies have proven efficacy of ID administration over subcutaneous (SC), intramuscular (IM) or other ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccine Controversies
Vaccine hesitancy is a delay in acceptance, or refusal of vaccines despite availability and supporting evidence. The term covers refusals to vaccinate, delaying vaccines, accepting vaccines but remaining uncertain about their use, or using certain vaccines but not others. Although adverse effects associated with vaccines are occasionally observed, the scientific consensus that vaccines are generally safe and effective is overwhelming. Vaccine hesitancy often results in disease outbreaks and deaths from vaccine-preventable diseases. Therefore, the World Health Organization characterizes vaccine hesitancy as one of the top ten global health threats. Vaccine hesitancy is complex and context-specific, varying across time, place and vaccines. It can be influenced by factors such as lack of proper scientifically based knowledge and understanding about how vaccines are made or work, as well as psychological factors including fear of needles and distrust of public authorities, a perso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Disasters In Germany
Health has a variety of definitions, which have been used for different purposes over time. In general, it refers to physical and emotional well-being, especially that associated with normal functioning of the human body, absent of disease, pain (including mental pain), or injury. Health can be promoted by encouraging healthful activities, such as regular physical exercise and adequate sleep, and by reducing or avoiding unhealthful activities or situations, such as smoking or excessive Stress (biology), stress. Some factors affecting health are due to Agency (sociology), individual choices, such as whether to engage in a high-risk behavior, while others are due to Social structure, structural causes, such as whether the society is arranged in a way that makes it easier or harder for people to get necessary healthcare services. Still, other factors are beyond both individual and group choices, such as genetic disorders. History The meaning of health has evolved over time. In k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
