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Lübeck Disaster
From 1929 to 1933, 251 infants in Lübeck, northern Germany, were given three doses of the oral BCG vaccine against tuberculosis, which was accidentally contaminated with the bacteria responsible for the disease. 173 later developed signs of the illness and 77 died. It was initially thought that of the 77, only 72 died of TB causes. Contaminated vaccine This vaccine itself was initially blamed, until an inquiry headed by of the Robert Koch Institute and Ludwig Lange of the Ministry of Health identified contamination as the cause. The event later became known as the Lübeck disaster, or in German, the ''Lübecker Impfunglück'' (Lübeck vaccine disaster). Major scientific journals worldwide commented on the disaster and subsequent trials of the medical staff, such as ''The Lancet'' and the ''Journal of the American Medical Association''. Legal consequences On 6 February 1932, , the head of the general hospital in Lübeck, was found guilty of negligent homicide and neglige ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lübeck
Lübeck (; or ; Latin: ), officially the Hanseatic League, Hanseatic City of Lübeck (), is a city in Northern Germany. With around 220,000 inhabitants, it is the second-largest city on the German Baltic Sea, Baltic coast and the second-largest city in the state of Schleswig-Holstein, after its capital of Kiel. It is the List of cities in Germany by population, 36th-largest city in Germany. The city lies in the Holsatian part of Schleswig-Holstein, on the mouth of the Trave, which flows into the Bay of Lübeck in the borough of Travemünde, and on the Trave's tributary Wakenitz. The island with the historic old town and the districts north of the Trave are also located in the historical region of Wagria. Lübeck is the southwesternmost city on the Baltic Sea, and the closest point of access to the Baltic from Hamburg. The city lies in the Northern Low Saxon, Holsatian dialect area of Low German. The name ''Lübeck'' ultimately stems from the Slavic languages, Slavic root (' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intradermal
Intradermal injection (also intracutaneous or intradermic, abbreviated as ID) is a shallow or superficial injection of a substance into the dermis, which is located between the epidermis and the hypodermis. For certain substances, administration via an ID route can result in a faster systemic uptake compared with subcutaneous injections, leading to a stronger immune response to vaccinations, immunology and novel cancer treatments, and faster drug uptake. Additionally, since administration is closer to the surface of the skin, the body's reaction to substances is more easily visible. However, due to complexity of the procedure compared to subcutaneous injection and intramuscular injection, administration via ID is relatively rare, and is only used for tuberculosis and allergy tests, monkeypox vaccination, and certain therapies. Vaccine dose sparing For vaccination many clinical studies have proven efficacy of ID administration over subcutaneous (SC), intramuscular (IM) or other ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vaccine Controversies
Vaccine hesitancy is a delay in acceptance, or refusal of vaccines despite availability and supporting evidence. The term covers refusals to vaccinate, delaying vaccines, accepting vaccines but remaining uncertain about their use, or using certain vaccines but not others. Although adverse effects associated with vaccines are occasionally observed, the scientific consensus that vaccines are generally safe and effective is overwhelming. Vaccine hesitancy often results in disease outbreaks and deaths from vaccine-preventable diseases. Therefore, the World Health Organization characterizes vaccine hesitancy as one of the top ten global health threats. Vaccine hesitancy is complex and context-specific, varying across time, place and vaccines. It can be influenced by factors such as lack of proper scientifically based knowledge and understanding about how vaccines are made or work, as well as psychological factors including fear of needles and distrust of public authorities, a perso ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Health Disasters In Germany
Health has a variety of definitions, which have been used for different purposes over time. In general, it refers to physical and emotional well-being, especially that associated with normal functioning of the human body, absent of disease, pain (including mental pain), or injury. Health can be promoted by encouraging healthful activities, such as regular physical exercise and adequate sleep, and by reducing or avoiding unhealthful activities or situations, such as smoking or excessive Stress (biology), stress. Some factors affecting health are due to Agency (sociology), individual choices, such as whether to engage in a high-risk behavior, while others are due to Social structure, structural causes, such as whether the society is arranged in a way that makes it easier or harder for people to get necessary healthcare services. Still, other factors are beyond both individual and group choices, such as genetic disorders. History The meaning of health has evolved over time. In k ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1930s Disasters In Germany
Year 193 ( CXCIII) was a common year starting on Monday of the Julian calendar. At the time, it was known as the Year of the Consulship of Sosius and Ericius (or, less frequently, year 946 ''Ab urbe condita''). The denomination 193 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * January 1 – Year of the Five Emperors: The Roman Senate chooses Publius Helvius Pertinax, against his will, to succeed the late Commodus as Emperor. Pertinax is forced to reorganize the handling of finances, which were wrecked under Commodus, to reestablish discipline in the Roman army, and to suspend the food programs established by Trajan, provoking the ire of the Praetorian Guard. * March 28 – Pertinax is assassinated by members of the Praetorian Guard, who storm the imperial palace. The Empire is auctioned off; Marcus Didius Julianus the highest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1929 In Germany
Nineteen or 19 may refer to: * 19 (number) * One of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (1987 film), a 1987 science fiction film * '' 19-Nineteen'', a 2009 South Korean film * '' Diciannove'', a 2024 Italian drama film informally referred to as "Nineteen" in some sources Science * Potassium, an alkali metal * 19 Fortuna, an asteroid Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album '' 63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle * "Stone in Focus", officially "#19", a composition by Aphex Twin * "Nineteen", a song from the 1992 album ''Refugee'' by Bad4Good * "Nineteen", a song from th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1930s Health Disasters
Year 193 ( CXCIII) was a common year starting on Monday of the Julian calendar. At the time, it was known as the Year of the Consulship of Sosius and Ericius (or, less frequently, year 946 ''Ab urbe condita''). The denomination 193 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Roman Empire * January 1 – Year of the Five Emperors: The Roman Senate chooses Publius Helvius Pertinax, against his will, to succeed the late Commodus as Emperor. Pertinax is forced to reorganize the handling of finances, which were wrecked under Commodus, to reestablish discipline in the Roman army, and to suspend the food programs established by Trajan, provoking the ire of the Praetorian Guard. * March 28 – Pertinax is assassinated by members of the Praetorian Guard, who storm the imperial palace. The Empire is auctioned off; Marcus Didius Julianus the highest ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1929 Health Disasters
Nineteen or 19 may refer to: * 19 (number) * One of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (1987 film), a 1987 science fiction film * ''19-Nineteen'', a 2009 South Korean film * ''Diciannove'', a 2024 Italian drama film informally referred to as "Nineteen" in some sources Science * Potassium, an alkali metal * 19 Fortuna, an asteroid Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle * "Stone in Focus", officially "#19", a composition by Aphex Twin * "Nineteen", a song from the 1992 album ''Refugee'' by Bad4Good * "Nineteen", a song from the 2001 alb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
East Germany
East Germany, officially known as the German Democratic Republic (GDR), was a country in Central Europe from Foundation of East Germany, its formation on 7 October 1949 until German reunification, its reunification with West Germany (FRG) on 3 October 1990. Until 1989, it was generally viewed as a communist state and described itself as a Socialist state, socialist "workers' and peasants' state". The Economy of East Germany, economy of the country was Central planning, centrally planned and government-owned corporation, state-owned. Although the GDR had to pay substantial war reparations to the Soviets, its economy became the most successful in the Eastern Bloc. Before its establishment, the country's territory was administered and occupied by Soviet forces following the Berlin Declaration (1945), Berlin Declaration abolishing German sovereignty in World War II. The Potsdam Agreement established the Soviet occupation zone in Germany, Soviet-occupied zone, bounded on the east b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bodily Harm
Bodily harm is a legal term of art used in the definition of both statutory and common law offences in Australia, Canada, England and Wales and other common law jurisdictions. It is a synonym for injury or bodily injury and similar expressions, though it may be used with a precise and limited meaning in any given jurisdiction. The expression grievous bodily harm first appeared in a statute in Lord Ellenborough's Act (1803). Canada In the Canadian Criminal Code, "bodily harm" is defined as "any hurt or injury to a person that interferes with the health or comfort of the person and that is more than merely transient or trifling in nature." England and Wales The expression is not defined by any statute. It currently appears in a number of offences under the Offences against the Person Act 1861 (ss. 18, 20, 23, 26, 28, 29, 31, 35, and 47) and in the offence of burglary under the Theft Act 1968 (s. 9). It is also used in the definition of murder (as it appears in case law) in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BCG Vaccine
The Bacillus Calmette–Guérin (BCG) vaccine is a vaccine primarily used against tuberculosis (TB). It is named after its inventors Albert Calmette and Camille Guérin. In countries where tuberculosis or leprosy is common, one dose is recommended in healthy babies as soon after birth as possible. In areas where tuberculosis is not common, only children at high risk are typically immunized, while suspected cases of tuberculosis are individually tested for and treated. Adults who do not have tuberculosis and have not been previously immunized, but are frequently exposed, may be immunized, as well. BCG also has some effectiveness against Buruli ulcer infection and other nontuberculous mycobacterial infections. Additionally, it is sometimes used as part of the treatment of bladder cancer. Rates of protection against tuberculosis infection vary widely and protection lasts up to 20 years. Among children, it prevents about 20% from getting infected and among those who do get inf ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Negligent Homicide
Negligent homicide is a criminal charge brought against a person who, through criminal negligence, allows another person to die. Other times, an intentional killing may be negotiated down to this lesser charge as a compromised resolution of a murder case, as might occur in the context of the intentional shooting of an unarmed man after a traffic altercation. Negligent homicide can be distinguished from involuntary manslaughter by its mens rea requirement: negligent homicide requires criminal negligence, while manslaughter requires recklessness. In the United Kingdom, common law gross negligent manslaughter covers the same conduct as negligent homicide. United States In the United States, all states define negligent homicide by statute, often defining the offense as involuntary manslaughter. Negligent homicide may be a lesser included offense to first and second degree murder, as the elements of negligent homicide include elements of those more serious charges. In some stat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
