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Kitasato Shibasaburō
Baron was a Japanese physician and bacteriologist. He is remembered as the co-discoverer of the infectious agent of bubonic plague in Hong Kong during an outbreak in 1894, almost simultaneously with Alexandre Yersin. Kitasato was nominated for the first annual Nobel Prize in Physiology or Medicine in 1901. Kitasato and Emil von Behring, working together in Berlin in 1890, announced the discovery of diphtheria antitoxin serum. Von Behring was awarded the 1901 Nobel Prize because of this work, but Kitasato was not. Biography Kitasato was born in Okuni village, Higo Province, (present-day Oguni Town, Kumamoto Prefecture, Kyūshū), the son of Kitasato Korenobu, a village head, and Tei, the daughter of a samurai. His parents were strict about his education and sent him to a relative's home and requested rigid discipline. He is said to have inherited his leadership qualities from his mother. He was educated at Kumamoto Medical School and a predecessor of Tokyo Imperial U ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kazoku
The was the hereditary peerage of the Empire of Japan, which existed between 1869 and 1947. It was formed by merging the feudal lords (''Daimyo, daimyō'') and court nobles (''kuge'') into one system modelled after the British peerage. Distinguished military officers, politicians, and scholars were occasionally ennobled until the country's defeat in the World War II, Second World War in 1945 (). The system was abolished with the Constitution of Japan, 1947 constitution, which prohibited any form of aristocracy under it, but ''kazoku'' descendants still form the core of the traditional upper class in the country's society, distinct from the nouveau riche. should not be confused with , which is pronounced the same in Japanese, but written with different characters, meaning "immediate family" (as in the film ''Kazoku (film), Kazoku'' above). Origins Following the Meiji Restoration of 1868, the ancient court nobility of Kyoto, the , regained some of its lost status. Several ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diphtheria
Diphtheria is an infection caused by the bacteria, bacterium ''Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild Course (medicine), clinical course, but in some outbreaks, the mortality rate approaches 10%. Signs and symptoms may vary from mild to severe, and usually start two to five days after exposure. Symptoms often develop gradually, beginning with a sore throat and fever. In severe cases, a grey or white patch develops in the throat, which can block the airway, and create a barking cough similar to what is observed in croup. The neck may also swell, in part due to the enlargement of the facial lymph nodes. Diphtheria can also involve the skin, eyes, or genitals, and can cause complications, including myocarditis (which in itself can result in an cardiac arrhythmia, abnormal heart rate), peripheral neuropathy, inflammation of nerves (which can result in paralysis), proteinuria, kidney problems, and bleeding problems due to thrombocytopenia, low ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Passive Immunity
In immunology, passive immunity is the transfer of active humoral immunity of ready-made antibodies. Passive immunity can occur naturally, when maternal antibodies are transferred to the fetus through the placenta, and it can also be induced artificially, when high levels of antibodies specific to a pathogen or toxin (obtained from humans, horses, or other animals) are transferred to non- immune persons through blood products that contain antibodies, such as in immunoglobulin therapy or antiserum therapy. Passive immunization is used when there is a high risk of infection and insufficient time for the body to develop its own immune response, or to reduce the symptoms of ongoing or immunosuppressive diseases. Passive immunization can be provided when people cannot synthesize antibodies, and when they have been exposed to a disease that they do not have immunity against. Naturally acquired Maternal passive immunity Maternal passive immunity is a type of naturally acquired passiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthrax Disease
Anthrax is an infection caused by the bacterium ''Bacillus anthracis'' or ''Bacillus cereus'' biovar ''anthracis''. Infection typically occurs by contact with the skin, inhalation, or intestinal absorption. Symptom onset occurs between one day and more than two months after the infection is contracted. The skin form presents with a small blister with surrounding swelling that often turns into a painless ulcer with a black center. The inhalation form presents with fever, chest pain, and shortness of breath. The intestinal form presents with diarrhea (which may contain blood), abdominal pains, nausea, and vomiting. According to the U.S. Centers for Disease Control and Prevention, the first clinical descriptions of cutaneous anthrax were given by Maret in 1752 and Fournier in 1769. Before that, anthrax had been described only in historical accounts. The German scientist Robert Koch was the first to identify ''Bacillus anthracis'' as the bacterium that causes anthrax. Anthrax ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emil Adolf Von Behring
Emil von Behring (; Emil Adolf von Behring: born Emil Adolf Behring; 15 March 1854 – 31 March 1917), was a German physiologist who received the 1901 Nobel Prize in Physiology or Medicine, the first one awarded in that field, for his discovery of a diphtheria antitoxin. He was widely known as a "saviour of children", as diphtheria used to be a major cause of child death. His work with the disease, as well as tetanus, has come to bring him most of his fame and acknowledgment. He was honoured with Prussian nobility in 1901, henceforth being known by the surname "von Behring". Biography Behring was born in Hansdorf, Kreis Rosenberg, Province of Prussia (now Ławice, Iława County, Poland). His father was a schoolmaster; the family had 13 children. Between 1874 and 1878, Behring studied medicine at the Kaiser-Wilhelm-Akademie in Berlin, an academy for military doctors, since his family could not afford the university. As a military doctor, he studied the action of iodoform. Due ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell Culture
Cell culture or tissue culture is the process by which cell (biology), cells are grown under controlled conditions, generally outside of their natural environment. After cells of interest have been Cell isolation, isolated from living tissue, they can subsequently be maintained under carefully controlled conditions. They need to be kept at body temperature (37 °C) in an incubator. These conditions vary for each cell type, but generally consist of a suitable vessel with a substrate or rich growth medium, medium that supplies the essential nutrients (amino acids, carbohydrates, vitamins, minerals), growth factors, hormones, and gases (Carbon dioxide, CO2, Oxygen, O2), and regulates the physio-chemical environment (Buffer solution, pH buffer, osmotic pressure, temperature). Most cells require a surface or an artificial substrate to form an adherent culture as a monolayer (one single-cell thick), whereas others can be grown free floating in a medium as a suspension culture. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetanus
Tetanus (), also known as lockjaw, is a bacterial infection caused by ''Clostridium tetani'' and characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body. Each spasm usually lasts for a few minutes. Spasms occur frequently for three to four weeks. Some spasms may be severe enough to bone fracture, fracture bones. Other symptoms of tetanus may include fever, sweating, headache, dysphagia, trouble swallowing, hypertension, high blood pressure, and a tachycardia, fast heart rate. The onset of symptoms is typically 3 to 21 days following infection. Recovery may take months; about 10% of cases prove to be death, fatal. ''C. tetani'' is commonly found in soil, saliva, dust, and manure. The bacteria generally enter through a break in the skin, such as a cut or puncture wound caused by a contaminated object. They produce toxins that interfere with normal muscle contractions. Diagnosis is based on the presenting signs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Humboldt University Of Berlin
The Humboldt University of Berlin (, abbreviated HU Berlin) is a public research university in the central borough of Mitte in Berlin, Germany. The university was established by Frederick William III on the initiative of Wilhelm von Humboldt, Johann Gottlieb Fichte and Friedrich Daniel Ernst Schleiermacher as the University of Berlin () in 1809, and opened in 1810. From 1828 until its closure in 1945, it was named the (Royal) Friedrich Wilhelm University of Berlin (FWU Berlin; ). During the Cold War, the university found itself in East Berlin and was ''de facto'' split in two when the Free University of Berlin opened in West Berlin. The university received its current name in honour of Alexander and Wilhelm von Humboldt in 1949. The university is divided into nine faculties including its medical school shared with the Freie Universität Berlin. The university has a student enrollment of around 35,000 students, and offers degree programs in some 171 disciplines from un ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Koch
Heinrich Hermann Robert Koch ( ; ; 11 December 1843 – 27 May 1910) was a German physician and microbiologist. As the discoverer of the specific causative agents of deadly infectious diseases including tuberculosis, cholera and anthrax, he is regarded as one of the main founders of modern bacteriology. As such he is popularly nicknamed the father of microbiology (with Louis Pasteur), and as the father of medical bacteriology. His discovery of the anthrax bacterium ('' Bacillus anthracis'') in 1876 is considered as the birth of modern bacteriology. Koch used his discoveries to establish that germs "could cause a specific disease" and directly provided proofs for the germ theory of diseases, therefore creating the scientific basis of public health, saving millions of lives. For his life's work Koch is seen as one of the founders of modern medicine. While working as a private physician, Koch developed many innovative techniques in microbiology. He was the first to use the oil ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Samurai
The samurai () were members of the warrior class in Japan. They were originally provincial warriors who came from wealthy landowning families who could afford to train their men to be mounted archers. In the 8th century AD, the imperial court downsized the national army and delegated the security of the countryside to these privately trained warriors. Eventually the samurai clans grew so powerful that they became the ''de facto'' rulers of the country. In the aftermath of the Gempei War (1180-1185), Japan formally passed into military rule with the founding of the first shogunate. The status of samurai became heredity by the mid-eleventh century. By the start of the Edo period, the shogun had disbanded the warrior-monk orders and peasant conscript system, leaving the samurai as the only men in the country permitted to carry weapons at all times. Because the Edo period was a time of peace, many samurai neglected their warrior training and focused on peacetime activities such as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nanushi
''Nanushi'' (Japanese: 名主) were officials in Japan who administered villages (''mura'') under a district magistrate (''gun-dai'') in the Edo period. The most powerful ''nanushi'', the ''ōjōya'' (大庄屋), administered up to several dozen villages, and were sometimes allowed privileges traditionally associated with the samurai class. The duties of a ''nanushi'' included tax collection and serving as the most local administrator of a rural village in direct contact with the villagers. The term ''nanushi'' was used in Kantō, while the official was called ''shōya'' (庄屋) in Kansai and ''kimoiri'' (肝煎) in Tōhoku and Hokuriku. Overview The duties of ''nanushi'' included tax collection, general village administration, management of public natural resources (such as mountain, field, river and ocean) of a village called ''iriai'', as well as negotiating with the territorial lord as the representative of the villagers. The most powerful ''nanushi'', the ''ōjōya'', ad ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Kyūshū
is the third-largest island of Japan's four main islands and the most southerly of the four largest islands (i.e. excluding Okinawa and the other Ryukyu (''Nansei'') Islands). In the past, it has been known as , and . The historical regional name referred to Kyushu and its surrounding islands. Kyushu has a land area of and a population of 14,311,224 in 2018. In ancient times, there is a theory that Kyushu was home to its own independent dynasty, where a unique, southern-influenced culture and tradition distinct from that of Honshu flourished. In the 8th-century Taihō Code reforms, Dazaifu was established as a special administrative term for the region. Geography The island is mountainous, and Japan's most active volcano, Mount Aso at , is on Kyūshū. There are many other signs of tectonic activity, including numerous areas of hot springs. The most famous of these are in Beppu, on the east shore, and around Mt. Aso in central Kyūshū. The island is separated f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
