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Hans Fischer
Hans Fischer (; 27 July 1881 – 31 March 1945) was a German organic chemist and the recipient of the 1930 Nobel Prize for Chemistry "for his researches into the constitution of haemin and chlorophyll and especially for his synthesis of haemin." Biography Early years Fischer was born on July 27,1881 in Höchst on river Main, now a city district of Frankfurt located in Germany. His parents were Dr. Eugen Fischer, Director of the firm of Kalle & Co, Wiesbaden, and Privatdozent at the Technical High School, Stuttgart, and Anna Herdegen was his mother. He went to a primary school in Stuttgart, and later to the "Humanistisches Gymnasium" in Wiesbaden, matriculating in 1899. He read chemistry and medicine, first at the University of Lausanne and then at Marburg. He graduated in 1904 obtaining his chemistry degree, 2 years later in 1906 he licensed for medicine and in 1908 he qualified for his M.D. including the Nobel Lecture, December 11, 1930 ''On Haemin and the Relationshi ...
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Höchst (Frankfurt Am Main)
Höchst ( or ) is a quarter of Frankfurt am Main, Germany. It is part of the ''Ortsbezirk West''. Höchst am Main was annexed by Frankfurt am Main in 1928, at the same time as Sindlingen, Unterliederbach and Zeilsheim. Höchst is situated 10 km west of downtown Frankfurt on the north bank of the Main river at the Nidda River estuary. The well-preserved old city has been under the '' Denkmalschutz'' protection law since 1972. An important cultural event is the folklore festival, the ''Höchster Schloßfest'', that brings many visitors to Höchst. It begins in the middle of June and last four weeks. It includes a festival in the old city, fireworks, and a jazz festival in the castle. In Höchst there is the Friedrich-Dessauer-Gymnasium, a sixth form '' Gymnasium''. History Middle Ages Höchst is first mentioned in 790 as Hostat (meaning high site or high place). The name has nothing to do with the Hostato Saga regarding the Knight Hostato, who after being the only one ...
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Adolf Stachel
Adolf Stachel (born 28 February 1913 in Augsburg, died 1971 in Frankfurt am Main) was a German chemist, researcher and inventor, who worked as a researcher at the chemical and pharmaceutical company Cassella (now Sanofi) in Frankfurt-Fechenheim for much of his career. He held a doctoral degree in chemistry (Doktoringenieur) from the Technische Hochschule München. Early in his career, he was a mentee and collaborator of the Nobel Prize-winning chemist Hans Fischer, who was his doctoral supervisor. He later became a researcher at Cassella. His patents were related to basically substituted heterocyclic compounds, e.g. 2,3-benzotriazine-4(3H)-one derivatives (coumarin), and basically substituted 1H,3H)-quinazoline-2-thion-4-one derivatives, having excellent coronary dilator properties. Patentee was Cassella. When working at Cassella, he was a close collaborator of Armin K.W. Kutzsche. Together with Werner Zerweck Werner Zerweck (14 March 1899 in Munich – 10 September 1965) was ...
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Marburg
Marburg ( or ) is a university town in the German federal state (''Bundesland'') of Hesse, capital of the Marburg-Biedenkopf district (''Landkreis''). The town area spreads along the valley of the river Lahn and has a population of approximately 76,000. Having been awarded town privileges in 1222, Marburg served as capital of the landgraviate of Hessen-Marburg during periods of the fifteenth to seventeenth centuries. The University of Marburg was founded in 1527 and dominates the public life in the town to this day. Marburg is a historic centre of the pharmaceutical industry in Germany, and there is a plant in the town (by BioNTech) to produce vaccines to tackle Covid-19. History Founding and early history Like many settlements, Marburg developed at the crossroads of two important early medieval highways: the trade route linking Cologne and Prague and the trade route from the North Sea to the Alps and on to Italy, the former crossing the river Lahn here. A first menti ...
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Medicine
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers fo ...
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Chemistry
Chemistry is the scientific study of the properties and behavior of matter. It is a natural science that covers the elements that make up matter to the compounds made of atoms, molecules and ions: their composition, structure, properties, behavior and the changes they undergo during a reaction with other substances. Chemistry also addresses the nature of chemical bonds in chemical compounds. In the scope of its subject, chemistry occupies an intermediate position between physics and biology. It is sometimes called the central science because it provides a foundation for understanding both basic and applied scientific disciplines at a fundamental level. For example, chemistry explains aspects of plant growth ( botany), the formation of igneous rocks ( geology), how atmospheric ozone is formed and how environmental pollutants are degraded ( ecology), the properties of the soil on the moon ( cosmochemistry), how medications work ( pharmacology), and how to collec ...
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Gymnasium (school)
''Gymnasium'' (and variations of the word) is a term in various European languages for a secondary school that prepares students for higher education at a university. It is comparable to the US English term '' preparatory high school''. Before the 20th century, the gymnasium system was a widespread feature of educational systems throughout many European countries. The word (), from Greek () 'naked' or 'nude', was first used in Ancient Greece, in the sense of a place for both physical and intellectual education of young men. The latter meaning of a place of intellectual education persisted in many European languages (including Albanian, Bulgarian, Estonian, Greek, German, Hungarian, the Scandinavian languages, Dutch, Polish, Czech, Serbo-Croatian, Macedonian, Slovak, Slovenian and Russian), whereas in other languages, like English (''gymnasium'', ''gym'') and Spanish (''gimnasio''), the former meaning of a place for physical education was retained. School struct ...
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Stuttgart
Stuttgart (; Swabian: ; ) is the capital and largest city of the German state of Baden-Württemberg. It is located on the Neckar river in a fertile valley known as the ''Stuttgarter Kessel'' (Stuttgart Cauldron) and lies an hour from the Swabian Jura and the Black Forest. Stuttgart has a population of 635,911, making it the sixth largest city in Germany. 2.8 million people live in the city's administrative region and 5.3 million people in its metropolitan area, making it the fourth largest metropolitan area in Germany. The city and metropolitan area are consistently ranked among the top 20 European metropolitan areas by GDP; Mercer listed Stuttgart as 21st on its 2015 list of cities by quality of living; innovation agency 2thinknow ranked the city 24th globally out of 442 cities in its Innovation Cities Index; and the Globalization and World Cities Research Network ranked the city as a Beta-status global city in their 2020 survey. Stuttgart was one of the host cities ...
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Wiesbaden
Wiesbaden () is a city in central western Germany and the capital of the state of Hesse. , it had 290,955 inhabitants, plus approximately 21,000 United States citizens (mostly associated with the United States Army). The Wiesbaden urban area is home to approximately 560,000 people. Wiesbaden is the second-largest city in Hesse after Frankfurt am Main. The city, together with nearby Frankfurt am Main, Darmstadt, and Mainz, is part of the Frankfurt Rhine Main Region, a metropolitan area with a combined population of about 5.8 million people. Wiesbaden is one of the oldest spa towns in Europe. Its name translates to "meadow baths", a reference to its famed hot springs. It is also internationally famous for its architecture and climate—it is also called the "Nice of the North" in reference to the city in France. At one time, Wiesbaden had 26 hot springs. , fourteen of the springs are still flowing. In 1970, the town hosted the tenth ''Hessentag Landesfest'' (English: H ...
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Frankfurt
Frankfurt, officially Frankfurt am Main (; Hessian: , " Frank ford on the Main"), is the most populous city in the German state of Hesse. Its 791,000 inhabitants as of 2022 make it the fifth-most populous city in Germany. Located on its namesake Main River, it forms a continuous conurbation with the neighboring city of Offenbach am Main and its urban area has a population of over 2.3 million. The city is the heart of the larger Rhine-Main metropolitan region, which has a population of more than 5.6 million and is Germany's second-largest metropolitan region after the Rhine-Ruhr region. Frankfurt's central business district, the Bankenviertel, lies about northwest of the geographic center of the EU at Gadheim, Lower Franconia. Like France and Franconia, the city is named after the Franks. Frankfurt is the largest city in the Rhine Franconian dialect area. Frankfurt was a city state, the Free City of Frankfurt, for nearly five centuries, and was one of th ...
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Chlorophyll
Chlorophyll (also chlorophyl) is any of several related green pigments found in cyanobacteria and in the chloroplasts of algae and plants. Its name is derived from the Greek words , ("pale green") and , ("leaf"). Chlorophyll allow plants to absorb energy from light. Chlorophylls absorb light most strongly in the blue portion of the electromagnetic spectrum as well as the red portion. Conversely, it is a poor absorber of green and near-green portions of the spectrum. Hence chlorophyll-containing tissues appear green because green light, diffusively reflected by structures like cell walls, is less absorbed. Two types of chlorophyll exist in the photosystems of green plants: chlorophyll ''a'' and ''b''. History Chlorophyll was first isolated and named by Joseph Bienaimé Caventou and Pierre Joseph Pelletier in 1817. The presence of magnesium in chlorophyll was discovered in 1906, and was that element's first detection in living tissue. After initial work done by German ch ...
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Haemin
Hemin (haemin; ferric chloride heme) is an iron-containing porphyrin with chlorine that can be formed from a heme group, such as heme B found in the hemoglobin of human blood. Chemistry Hemin is protoporphyrin IX containing a ferric iron (Fe3+) ion with a coordinating chloride ligand. Chemically, hemin differs from the related heme-compound hematin chiefly in that the coordinating ion is a chloride ion in hemin, whereas the coordinating ion is a hydroxide ion in hematin. The iron ion in haem is ferrous (Fe2+), whereas it is ferric (Fe3+) in both hemin and hematin. Hemin is endogenously produced in the human body, for example during the turnover of old red blood cells. It can form inappropriately as a result of hemolysis or vascular injury. Several proteins in human blood bind to hemin, such as hemopexin and serum albumin. Pharmacological use A lyophilised form of hemin is used as a pharmacological agent in certain cases for the treatment of porphyria attacks, particular ...
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Organic Chemistry
Organic chemistry is a subdiscipline within chemistry involving the scientific study of the structure, properties, and reactions of organic compounds and organic materials, i.e., matter in its various forms that contain carbon atoms.Clayden, J.; Greeves, N. and Warren, S. (2012) ''Organic Chemistry''. Oxford University Press. pp. 1–15. . Study of structure determines their structural formula. Study of properties includes physical and chemical properties, and evaluation of chemical reactivity to understand their behavior. The study of organic reactions includes the chemical synthesis of natural products, drugs, and polymers, and study of individual organic molecules in the laboratory and via theoretical ( in silico) study. The range of chemicals studied in organic chemistry includes hydrocarbons (compounds containing only carbon and hydrogen) as well as compounds based on carbon, but also containing other elements, especially oxygen, nitrogen, sulfur, phosphorus (i ...
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