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Gray (unit)
The gray (symbol: Gy) is the unit of ionizing radiation dose in the International System of Units (SI), defined as the absorption of one joule of radiation energy per kilogram of matter. It is used as a unit of the radiation quantity absorbed dose that measures the energy deposited by ionizing radiation in a unit mass of absorbing material, and is used for measuring the delivered dose in radiotherapy, food irradiation and radiation sterilization. It is important in predicting likely acute health effects, such as acute radiation syndrome and is used to calculate equivalent dose using the sievert, which is a measure of the stochastic health effect on the human body. The gray is also used in radiation metrology as a unit of the radiation quantity kerma (physics), kerma; defined as the sum of the initial kinetic energy , kinetic energies of all the charged particles liberated by uncharged ionizing radiation in a sample of matter per unit mass. The unit was named after British phys ...
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Absorbed Dose
Absorbed dose is a dose quantity which represents the specific energy (energy per unit mass) deposited by ionizing radiation in living matter. Absorbed dose is used in the calculation of dose uptake in living tissue in both radiation protection (reduction of harmful effects), and radiology (potential beneficial effects, for example in cancer treatment). It is also used to directly compare the effect of radiation on inanimate matter such as in radiation hardening. The SI unit of measure is the Gray (unit), gray (Gy), which is defined as one joule of energy absorbed per kilogram of matter. The older, non-SI Centimetre–gram–second system of units, CGS unit rad (unit), rad, is sometimes also used, predominantly in the USA. Deterministic effects Conventionally, in radiation protection, unmodified absorbed dose is only used for indicating the immediate health effects due to high levels of acute dose. These are tissue effects, such as in acute radiation syndrome, which are also kn ...
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Acute Radiation Syndrome
Acute radiation syndrome (ARS), also known as radiation sickness or radiation poisoning, is a collection of health effects that are caused by being exposed to high amounts of ionizing radiation in a short period of time. Symptoms can start within an hour of exposure, and can last for several months. Early symptoms are usually nausea, vomiting and loss of appetite. In the following hours or weeks, initial symptoms may appear to improve, before the development of additional symptoms, after which either recovery or death follows. ARS involves a total dose of greater than 0.7 Gy (70 rad), that generally occurs from a source outside the body, delivered within a few minutes. Sources of such radiation can occur accidentally or intentionally. They may involve nuclear reactors, cyclotrons, certain devices used in cancer therapy, nuclear weapons, or radiological weapons. It is generally divided into three types: bone marrow, gastrointestinal, and neurovascular syndrome, with bone m ...
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Epithelium
Epithelium or epithelial tissue is a thin, continuous, protective layer of cells with little extracellular matrix. An example is the epidermis, the outermost layer of the skin. Epithelial ( mesothelial) tissues line the outer surfaces of many internal organs, the corresponding inner surfaces of body cavities, and the inner surfaces of blood vessels. Epithelial tissue is one of the four basic types of animal tissue, along with connective tissue, muscle tissue and nervous tissue. These tissues also lack blood or lymph supply. The tissue is supplied by nerves. There are three principal shapes of epithelial cell: squamous (scaly), columnar, and cuboidal. These can be arranged in a singular layer of cells as simple epithelium, either simple squamous, simple columnar, or simple cuboidal, or in layers of two or more cells deep as stratified (layered), or ''compound'', either squamous, columnar or cuboidal. In some tissues, a layer of columnar cells may appear to be stratified due t ...
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Radiation Therapy
Radiation therapy or radiotherapy (RT, RTx, or XRT) is a therapy, treatment using ionizing radiation, generally provided as part of treatment of cancer, cancer therapy to either kill or control the growth of malignancy, malignant cell (biology), cells. It is normally delivered by a linear particle accelerator. Radiation therapy may be cure, curative in a number of types of cancer if they are localized to one area of the body, and have not metastasis, spread to other parts. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the canc ...
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Radiobiology
Radiobiology (also known as radiation biology, and uncommonly as actinobiology) is a field of clinical and basic medical sciences that involves the study of the effects of radiation on living tissue (including ionizing radiation, ionizing and non-ionizing radiation), in particular health effects of radiation. Ionizing radiation is generally harmful and potentially lethal to living things but can have health benefits in radiation therapy for the treatment of cancer and thyrotoxicosis. Its most common impact is the radiation-induced cancer, induction of cancer with a Incubation period, latent period of years or decades after exposure. High doses can cause visually dramatic radiation burns, and/or rapid fatality through acute radiation syndrome. Controlled doses are used for medical imaging and radiotherapy. Health effects In general, ionizing radiation is harmful and potentially lethal to living beings but can have health benefits in radiation therapy for the treatment of cancer an ...
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Dose Quantities And Units
Dose or Dosage may refer to: Music * ''Dose'' (Gov't Mule album), 1998 * ''Dose'' (Latin Playboys album) * ''Dosage'' (album), by the band Collective Soul * "Dose" (song), a 2018 song by Ciara * "Dose", song by Filter from the album '' Short Bus'' Science * Dose (biochemistry), a measured quantity of a medicine, nutrient, or pathogen which is delivered as a unit. * Dosage (pharmacology), prescribed regimen of medication administration, including amount, frequency, and duration * Dosage form, a mixture of active and inactive components used to administer a medication * Dosing, feeding chemicals or medicines when used in small quantities * Effective dose (pharmacology), a dose or concentration of a drug that produces a biological response * Absorbed dose, a measure of energy deposited in matter from ionizing radiation * Equivalent dose, a measure of cancer/heritable health risk in tissue from ionizing radiation * Effective dose (radiation), a measure of cancer/heritable h ...
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National Institute Of Standards And Technology
The National Institute of Standards and Technology (NIST) is an agency of the United States Department of Commerce whose mission is to promote American innovation and industrial competitiveness. NIST's activities are organized into Outline of physical science, physical science laboratory programs that include Nanotechnology, nanoscale science and technology, engineering, information technology, neutron research, material measurement, and physical measurement. From 1901 to 1988, the agency was named the National Bureau of Standards. History Background The Articles of Confederation, ratified by the colonies in 1781, provided: The United States in Congress assembled shall also have the sole and exclusive right and power of regulating the alloy and value of coin struck by their own authority, or by that of the respective states—fixing the standards of weights and measures throughout the United States. Article 1, section 8, of the Constitution of the United States, ratified i ...
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Rad (unit)
The rad is a unit of absorbed radiation dose, defined as 1 rad = 0.01 Gy = 0.01 J/kg. It was originally defined in CGS units in 1953 as the dose causing 100 ergs of energy to be absorbed by one gram of matter. The material absorbing the radiation can be human tissue, air, water, or any other substance. It has been replaced by the gray (symbol Gy) in SI derived units. The rad is still used in the United States, although this is "strongly discouraged" in Chapter 5.2 of the ''Guide to the SI'', which was written and published by the U.S. National Institute of Standards and Technology. However, the numerically equivalent SI unit submultiple, the centigray (symbol cGy), is widely used to report absorbed doses within radiotherapy. The roentgen, used to quantify the radiation exposure, may be related to the corresponding absorbed dose by use of the F-factor. Health effects A dose of under 100 rad will typically produce no immediate symptoms other than blood changes. A dose o ...
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Neutron
The neutron is a subatomic particle, symbol or , that has no electric charge, and a mass slightly greater than that of a proton. The Discovery of the neutron, neutron was discovered by James Chadwick in 1932, leading to the discovery of nuclear fission in 1938, the first self-sustaining nuclear reactor (Chicago Pile-1, 1942) and the first nuclear weapon (Trinity (nuclear test), Trinity, 1945). Neutrons are found, together with a similar number of protons in the atomic nucleus, nuclei of atoms. Atoms of a chemical element that differ only in neutron number are called isotopes. Free neutrons are produced copiously in nuclear fission and nuclear fusion, fusion. They are a primary contributor to the nucleosynthesis of chemical elements within stars through fission, fusion, and neutron capture processes. Neutron stars, formed from massive collapsing stars, consist of neutrons at the density of atomic nuclei but a total mass more than the Sun. Neutron properties and interactions ar ...
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Photon
A photon () is an elementary particle that is a quantum of the electromagnetic field, including electromagnetic radiation such as light and radio waves, and the force carrier for the electromagnetic force. Photons are massless particles that can move no faster than the speed of light measured in vacuum. The photon belongs to the class of boson particles. As with other elementary particles, photons are best explained by quantum mechanics and exhibit wave–particle duality, their behavior featuring properties of both waves and particles. The modern photon concept originated during the first two decades of the 20th century with the work of Albert Einstein, who built upon the research of Max Planck. While Planck was trying to explain how matter and electromagnetic radiation could be in thermal equilibrium with one another, he proposed that the energy stored within a material object should be regarded as composed of an integer number of discrete, equal-sized parts. To explain the pho ...
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Charged Particle
In physics, a charged particle is a particle with an electric charge. For example, some elementary particles, like the electron or quarks are charged. Some composite particles like protons are charged particles. An ion, such as a molecule or atom with a surplus or deficit of electrons relative to protons are also charged particles. A Plasma (physics), plasma is a collection of charged particles, atomic nuclei and separated electrons, but can also be a gas containing a significant proportion of charged particles. Charged particles are labeled as either '' positive'' (+) or ''negative'' (-). The designations are arbitrary. Nothing is inherent to a positively charged particle that makes it "positive", and the same goes for negatively charged particles. Examples Positively charged particles * protons * positrons (antielectrons) * positively charged pions * alpha particles * ion, cations Negatively charged particles * electrons * antiprotons * muons * tauons * negative charged ...
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Kinetic Energy
In physics, the kinetic energy of an object is the form of energy that it possesses due to its motion. In classical mechanics, the kinetic energy of a non-rotating object of mass ''m'' traveling at a speed ''v'' is \fracmv^2.Resnick, Robert and Halliday, David (1960) ''Physics'', Section 7-5, Wiley International Edition The kinetic energy of an object is equal to the work, or force ( F) in the direction of motion times its displacement ( s), needed to accelerate the object from rest to its given speed. The same amount of work is done by the object when decelerating from its current speed to a state of rest. The SI unit of energy is the joule, while the English unit of energy is the foot-pound. In relativistic mechanics, \fracmv^2 is a good approximation of kinetic energy only when ''v'' is much less than the speed of light. History and etymology The adjective ''kinetic'' has its roots in the Greek word κίνησις ''kinesis'', meaning "motion". The dichotomy between ...
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