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Franz Ziehl
Franz Ziehl (13 April 1857 in Wismar – 7 April 1926) was a German bacteriologist. He was a professor in Lübeck. Franz Ziehl introduced the carbol fuchsin stain for the tubercle bacillus in 1882. With pathologist Friedrich Neelsen (1854–1898), he developed the Ziehl–Neelsen stain, also known as the acid-fast stain, which is used to identify acid-fast bacteria Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of prokaryotic microorganisms. Typically a few micrometr .... External links Mondofacto Dictionary (definitions) 1857 births 1926 deaths German bacteriologists Physicians from Lübeck People from Wismar People from the Grand Duchy of Mecklenburg-Schwerin {{Germany-biologist-stub ...
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Wismar
Wismar (; Low German: ''Wismer''), officially the Hanseatic City of Wismar (''Hansestadt Wismar'') is, with around 43,000 inhabitants, the sixth-largest city of the northeastern German state of Mecklenburg-Vorpommern, and the fourth-largest city of Mecklenburg after Rostock, Schwerin and Neubrandenburg. The city was the third-largest port city in former East Germany after Rostock and Stralsund. Wismar is located on the Bay of Wismar of the Baltic Sea, directly opposite the island of Poel, that separates the Bay of Wismar from the larger Bay of Mecklenburg. The city lies in the middle between the two larger port cities of Lübeck in the west, and Rostock in the east, and the state capital of Schwerin is located south of the city on Lake Schwerin. Wismar lies in the northeastern corner of the Hamburg Metropolitan Region, and is the capital of the district of Nordwestmecklenburg, Northwestern Mecklenburg. The city's natural harbour is protected by a promontory. The uninhabited island ...
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Bacteriologist
A bacteriologist is a microbiologist, or similarly trained professional, in bacteriology -- a subdivision of microbiology that studies bacteria, typically pathogenic ones. Bacteriologists are interested in studying and learning about bacteria, as well as using their skills in clinical settings. This includes investigating properties of bacteria such as morphology, ecology, genetics and biochemistry, phylogenetics, genomics and many other areas related to bacteria like disease diagnostic testing. Alongside human and animal healthcare providers, they may carry out various functions as medical scientists, veterinary scientists, or diagnostic technicians in locations like clinics, blood banks, hospitals, laboratories and animal hospitals. Bacteriologists working in public health or biomedical research help develop vaccines for public use. Bacteriologist specializations * Pathology * Immunology * Cell Biology * Medical Laboratory Science * Biomedical Research * Health T ...
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Lübeck
Lübeck (; Low German also ), officially the Hanseatic City of Lübeck (german: Hansestadt Lübeck), is a city in Northern Germany. With around 217,000 inhabitants, Lübeck is the second-largest city on the German Baltic coast and in the state of Schleswig-Holstein, after its capital of Kiel, and is the 35th-largest city in Germany. The city lies in Holstein, northeast of Hamburg, on the mouth of the River Trave, which flows into the Bay of Lübeck in the borough of Travemünde, and on the Trave's tributary Wakenitz. The city is part of the Hamburg Metropolitan Region, and is the southwesternmost city on the Baltic, as well as the closest point of access to the Baltic from Hamburg. The port of Lübeck is the second-largest German Baltic port after the port of Rostock. The city lies in the Northern Low Saxon dialect area of Low German. Lübeck is famous for having been the cradle and the ''de facto'' capital of the Hanseatic League. Its city centre is Germany's most extens ...
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Carbol Fuchsin
Carbol fuchsin, carbol-fuchsin, carbolfuchsin, or Castellani's paint (CAS ) is a mixture of phenol and basic fuchsin that is used in bacterial staining procedures. It is commonly used in the staining of mycobacteria because it has an affinity for the mycolic acids found in their cell membranes. It is a component of Ziehl–Neelsen stain, a differential stain. Carbol fuchsin is used as the primary stain dye to detect acid-fast bacteria because it is more soluble in the cells' wall lipids than in the acid alcohol. If the bacteria is acid-fast the bacteria will retain the initial red color of the dye because they are able to resist the destaining by acid alcohol (0.4–1% HCl in 70% EtOH). Additionally, it can be used for the staining of bacterial spores. Carbol-fuchsin is also used as a topical antiseptic and antifungal An antifungal medication, also known as an antimycotic medication, is a pharmaceutical fungicide or fungistatic used to treat and prevent mycosis such as ...
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Bacillus
''Bacillus'' (Latin "stick") is a genus of Gram-positive, rod-shaped bacteria, a member of the phylum '' Bacillota'', with 266 named species. The term is also used to describe the shape (rod) of other so-shaped bacteria; and the plural ''Bacilli'' is the name of the class of bacteria to which this genus belongs. ''Bacillus'' species can be either obligate aerobes which are dependent on oxygen, or facultative anaerobes which can survive in the absence of oxygen. Cultured ''Bacillus'' species test positive for the enzyme catalase if oxygen has been used or is present. ''Bacillus'' can reduce themselves to oval endospores and can remain in this dormant state for years. The endospore of one species from Morocco is reported to have survived being heated to 420 °C. Endospore formation is usually triggered by a lack of nutrients: the bacterium divides within its cell wall, and one side then engulfs the other. They are not true spores (i.e., not an offspring). Endospore formatio ...
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Pathologist
Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in the context of modern medical treatment, the term is often used in a narrower fashion to refer to processes and tests that fall within the contemporary medical field of "general pathology", an area which includes a number of distinct but inter-related medical specialties that diagnose disease, mostly through analysis of tissue, cell, and body fluid samples. Idiomatically, "a pathology" may also refer to the predicted or actual progression of particular diseases (as in the statement "the many different forms of cancer have diverse pathologies", in which case a more proper choice of word would be " pathophysiologies"), and the affix ''pathy'' is sometimes used to indicate a state of disease in cases of both physical ailment (as in cardiomy ...
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Friedrich Neelsen
Friedrich Carl Adolf Neelsen (March 29, 1854, Uetersen – April 11, 1894, Dresden) was a German pathologist. Life Friedrich C.A. Neelsen was born to Hans Friedrich Neelsen, deacon of the Uetersen vicarage, and his wife Bertha Sophia (née Lueders). He attended school in Uetersen and later in Altona. He studied medicine at the University of Leipzig, from which he received his doctorate at the age of 22. Later he became a professor at the Institute of Pathology of the University of Rostock. His final years were spent as chief of medicine at the famous pathological institute of the Dresden University of Technology. Neelsen died on April 11, 1894, aged 40, presumably due to pathogen exposure during his many years of bacteriological research. He was known in his time as a recluse who avoided public attention whenever possible, though he was active in the civic affairs of his hometown throughout his life. Work Together with microbiologist Franz Ziehl, Neelsen developed the Ziehl–Nee ...
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Ziehl–Neelsen Stain
Ziehl–Neelsen staining is a type of acid-fast stain, first introduced by Paul Ehrlich. Ziehl–Neelsen staining is a bacteriological stain used to identify acid-fast organisms, mainly Mycobacteria. It is named for two German doctors who modified the stain: the bacteriologist Franz Ziehl (1859–1926) and the pathologist Friedrich Neelsen (1854–1898). Mycobacteria In anatomic pathology specimens, immunohistochemistry and modifications of Ziehl–Neelsen staining (such as the Fite-Faraco method) have comparable diagnostic utility. Both of them are superior to traditional Ziehl–Neelsen staining. The genus ''Mycobacterium'' is a slow growing bacteria, made up of small rods that are slightly curved or straight, and are considered to be gram positive. Some mycobacteria are free-living saprophytes, but many are pathogens that cause disease in animals and humans. ''Mycobacterium bovis'' causes tuberculosis in cattle. Since tuberculosis can be spread to humans, milk is pasteuriz ...
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Acid-fast
Acid-fastness is a physical property of certain bacterial and eukaryotic cells, as well as some sub-cellular structures, specifically their resistance to decolorization by acids during laboratory staining procedures. Once stained as part of a sample, these organisms can resist the acid and/or ethanol-based decolorization procedures common in many staining protocols, hence the name ''acid-fast''. The mechanisms of acid-fastness vary by species, although the most well-known example is in the genus ''Mycobacterium'', which includes the species responsible for tuberculosis and leprosy. The acid-fastness of ''Mycobacteria'' is due to the high mycolic acid content of their cell walls, which is responsible for the staining pattern of poor absorption followed by high retention. Some bacteria may also be partially acid-fast, such as ''Nocardia''. Acid-fast organisms are difficult to characterize using standard microbiological techniques, though they can be stained using concentrated dyes ...
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Bacteria
Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one Cell (biology), biological cell. They constitute a large domain (biology), domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among the first life forms to appear on Earth, and are present in most of its habitats. Bacteria inhabit soil, water, Hot spring, acidic hot springs, radioactive waste, and the deep biosphere of Earth's crust. Bacteria are vital in many stages of the nutrient cycle by recycling nutrients such as the nitrogen fixation, fixation of nitrogen from the Earth's atmosphere, atmosphere. The nutrient cycle includes the decomposition of cadaver, dead bodies; bacteria are responsible for the putrefaction stage in this process. In the biological communities surrounding hydrothermal vents and cold seeps, extremophile bacteria provide the nutrients needed to sustain life by converting dissolved compounds, such as hydrogen sulp ...
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1857 Births
Events January–March * January 1 – The biggest Estonian newspaper, '' Postimees'', is established by Johann Voldemar Jannsen. * January 7 – The partly French-owned London General Omnibus Company begins operating. * January 9 – The 7.9 Fort Tejon earthquake shakes Central and Southern California, with a maximum Mercalli intensity of IX (''Violent''). * January 24 – The University of Calcutta is established in Calcutta, as the first multidisciplinary modern university in South Asia. The University of Bombay is also established in Bombay, British India, this year. * February 3 – The National Deaf Mute College (later renamed Gallaudet University) is established in Washington, D.C., becoming the first school for the advanced education of the deaf. * February 5 – The Federal Constitution of the United Mexican States is promulgated. * March – The Austrian garrison leaves Bucharest. * March 3 ** France and the United Kingdom ...
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1926 Deaths
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * '' Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by S ...
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