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Emil Adolf Von Behring
Emil von Behring (; Emil Adolf von Behring: born Emil Adolf Behring; 15 March 1854 – 31 March 1917), was a German physiologist who received the 1901 Nobel Prize in Physiology or Medicine, the first one awarded in that field, for his discovery of a diphtheria antitoxin. He was widely known as a "saviour of children", as diphtheria used to be a major cause of child death. His work with the disease, as well as tetanus, has come to bring him most of his fame and acknowledgment. He was honoured with Prussian nobility in 1901, henceforth being known by the surname "von Behring". Biography Behring was born in Hansdorf, Kreis Rosenberg, Province of Prussia (now Ławice, Iława County, Poland). His father was a schoolmaster; the family had 13 children. Between 1874 and 1878, Behring studied medicine at the Kaiser-Wilhelm-Akademie in Berlin, an academy for military doctors, since his family could not afford the university. As a military doctor, he studied the action of iodoform. Due ...
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Ławice
Ławice (German ''Hansdorf'') is a village in the administrative district of Gmina Iława, within Iława County, Warmian-Masurian Voivodeship, in northern Poland. It lies approximately east of Iława and west of the regional capital Olsztyn. Notable residents * Emil Adolf von Behring (1854–1917), Nobel laureate, discovered a diphtheria antitoxin An antitoxin is an antibody with the ability to neutralize a specific toxin. Antitoxins are produced by certain animals, plants, and bacterium, bacteria in response to toxin exposure. Although they are most effective in neutralizing toxins, the ... References Villages in Iława County {{Iława-geo-stub ...
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Diphtheria
Diphtheria is an infection caused by the bacteria, bacterium ''Corynebacterium diphtheriae''. Most infections are asymptomatic or have a mild Course (medicine), clinical course, but in some outbreaks, the mortality rate approaches 10%. Signs and symptoms may vary from mild to severe, and usually start two to five days after exposure. Symptoms often develop gradually, beginning with a sore throat and fever. In severe cases, a grey or white patch develops in the throat, which can block the airway, and create a barking cough similar to what is observed in croup. The neck may also swell, in part due to the enlargement of the facial lymph nodes. Diphtheria can also involve the skin, eyes, or genitals, and can cause complications, including myocarditis (which in itself can result in an cardiac arrhythmia, abnormal heart rate), peripheral neuropathy, inflammation of nerves (which can result in paralysis), proteinuria, kidney problems, and bleeding problems due to thrombocytopenia, low ...
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Hygienics
Hygiene is a set of practices performed to preserve health. According to the World Health Organization (WHO), "Hygiene refers to conditions and practices that help to maintain health and prevent the spread of diseases." Personal hygiene refers to maintaining the body's cleanliness. Hygiene activities can be grouped into the following: home and everyday hygiene, personal hygiene, medical hygiene, sleep hygiene, and food hygiene. Home and every day hygiene includes hand washing, respiratory hygiene, food hygiene at home, hygiene in the kitchen, hygiene in the bathroom, laundry hygiene, and medical hygiene at home. And also environmental hygiene in the society to prevent all kinds of bacterias from penetrating into our homes. Many people equate hygiene with "cleanliness", but hygiene is a broad term. It includes such personal habit choices as how frequently to take a shower or bath, wash hands, trim fingernails, and wash clothes. It also includes attention to keeping surfaces in ...
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Serum (blood)
Serum () is the fluid and solvent component of blood which does not play a role in clotting. It may be defined as blood plasma without the clotting factors, or as blood with all cells and clotting factors removed. Serum contains all proteins except clotting factors (involved in blood clotting), including all electrolytes, antibodies, antigens, hormones; and any exogenous substances (e.g., drugs, microorganisms). Serum also does not contain all the formed elements of blood, which include blood cells, white blood cells ( leukocytes, lymphocytes), red blood cells ( erythrocytes), and platelets. The study of serum is serology. Serum is used in numerous diagnostic tests as well as blood typing. Measuring the concentration of various molecules can be useful for many applications, such as determining the therapeutic index of a drug candidate in a clinical trial. To obtain serum, a blood sample is allowed to clot ( coagulation). The sample is then centrifuged to remove th ...
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Antibodies
An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to identify and neutralize antigens such as bacteria and viruses, including those that cause disease. Each individual antibody recognizes one or more specific antigens, and antigens of virtually any size and chemical composition can be recognized. Antigen literally means "antibody generator", as it is the presence of an antigen that drives the formation of an antigen-specific antibody. Each of the branching chains comprising the "Y" of an antibody contains a paratope that specifically binds to one particular epitope on an antigen, allowing the two molecules to bind together with precision. Using this mechanism, antibodies can effectively "tag" the antigen (or a microbe or an infected cell bearing such an antigen) for attack by cells of the immune system, or can neutralize it directly (for example, by blocking a part of a viru ...
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Guinea-pig
The guinea pig or domestic guinea pig (''Cavia porcellus''), also known as the cavy or domestic cavy ( ), is a species of rodent belonging to the genus ''Cavia'', family Caviidae. Breeders tend to use the name "cavy" for the animal, but "guinea pig" is more commonly used in scientific and laboratory contexts. Despite their name, guinea pigs are not native to Guinea, nor are they closely related to pigs. Instead, they originated in the Andes region of South America, where wild guinea pigs can still be found today. Studies based on biochemistry and DNA hybridization suggest they are domesticated animals that do not exist naturally in the wild, but are descendants of a closely related cavy species such as '' C. tschudii''. Originally, they were domesticated as livestock (source of meat) in the Andean region and are still consumed in some parts of the world. In Western society, the guinea pig has enjoyed widespread popularity as a pet since its introduction to Europe and N ...
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Tetanus
Tetanus (), also known as lockjaw, is a bacterial infection caused by ''Clostridium tetani'' and characterized by muscle spasms. In the most common type, the spasms begin in the jaw and then progress to the rest of the body. Each spasm usually lasts for a few minutes. Spasms occur frequently for three to four weeks. Some spasms may be severe enough to bone fracture, fracture bones. Other symptoms of tetanus may include fever, sweating, headache, dysphagia, trouble swallowing, hypertension, high blood pressure, and a tachycardia, fast heart rate. The onset of symptoms is typically 3 to 21 days following infection. Recovery may take months; about 10% of cases prove to be death, fatal. ''C. tetani'' is commonly found in soil, saliva, dust, and manure. The bacteria generally enter through a break in the skin, such as a cut or puncture wound caused by a contaminated object. They produce toxins that interfere with normal muscle contractions. Diagnosis is based on the presenting signs ...
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Kitasato Shibasaburō
Baron was a Japanese physician and bacteriologist. He is remembered as the co-discoverer of the infectious agent of bubonic plague in Hong Kong during an outbreak in 1894, almost simultaneously with Alexandre Yersin. Kitasato was nominated for the first annual Nobel Prize in Physiology or Medicine in 1901. Kitasato and Emil von Behring, working together in Berlin in 1890, announced the discovery of diphtheria antitoxin serum. Von Behring was awarded the 1901 Nobel Prize because of this work, but Kitasato was not. Biography Kitasato was born in Okuni village, Higo Province, (present-day Oguni Town, Kumamoto Prefecture, Kyūshū), the son of Kitasato Korenobu, a village head, and Tei, the daughter of a samurai. His parents were strict about his education and sent him to a relative's home and requested rigid discipline. He is said to have inherited his leadership qualities from his mother. He was educated at Kumamoto Medical School and a predecessor of Tokyo Imperial U ...
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Leukemia
Leukemia ( also spelled leukaemia; pronounced ) is a group of blood cancers that usually begin in the bone marrow and produce high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or '' leukemia cells''. Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. These symptoms occur due to a lack of normal blood cells. Diagnosis is typically made by blood tests or bone marrow biopsy. The exact cause of leukemia is unknown. A combination of genetic factors and environmental (non-inherited) factors are believed to play a role. Risk factors include smoking, ionizing radiation, petrochemicals (such as benzene), prior chemotherapy, and Down syndrome. People with a family history of leukemia are also at higher risk. There are four main types of leukemia—acute lymphoblastic leukemia (ALL), acute myeloid leukemia (AML), chronic lymphocytic leukemia (CLL) and chronic myelo ...
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Poznań
Poznań ( ) is a city on the Warta, River Warta in west Poland, within the Greater Poland region. The city is an important cultural and business center and one of Poland's most populous regions with many regional customs such as Saint John's Fair, Poznań, Saint John's Fair (''Jarmark Świętojański''), traditional St. Martin's croissant, Saint Martin's croissants and a local dialect. Among its most important heritage sites are the Renaissance in Poland, Renaissance Old Town, Poznań Town Hall, Town Hall and Poznań Cathedral. Poznań is the fifth-largest List of cities and towns in Poland#Cities, city in Poland. As of 2023, the city's population is 540,146, while the Poznań metropolitan area (''Metropolia Poznań'') comprising Poznań County and several other communities is inhabited by over 1.029 million people. It is one of four historical capitals of medieval Poland and the ancient capital of the Greater Poland region, currently the administrative capital of the pr ...
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Iodoform
Iodoform (also known as triiodomethane) is the organoiodine compound with the chemical formula . It is a pale yellow, crystalline, volatile substance, with a penetrating and distinctive odor (in older chemistry texts, the smell is sometimes referred to as that of hospitals, where the compound is still commonly used) and, analogous to chloroform, sweetish taste. It is occasionally used as a disinfectant. Naming The name iodoform originates with the "formyle radical," an archaic term for the HC moiety, and is retained for historical consistency. A full, modern name is triiodomethane. Another possible name is "carbon hydride triiodide". The "hydride" in the latter is sometimes omitted, though the IUPAC recommends against doing so, as "carbon triiodide" could also mean (hexaiodoethane, a highly unstable compound). Structure The molecule adopts a tetrahedral molecular geometry, tetrahedral geometry with C3v symmetry group, symmetry. Synthesis and reactions The synthesis of iodofo ...
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Berlin
Berlin ( ; ) is the Capital of Germany, capital and largest city of Germany, by both area and List of cities in Germany by population, population. With 3.7 million inhabitants, it has the List of cities in the European Union by population within city limits, highest population within its city limits of any city in the European Union. The city is also one of the states of Germany, being the List of German states by area, third smallest state in the country by area. Berlin is surrounded by the state of Brandenburg, and Brandenburg's capital Potsdam is nearby. The urban area of Berlin has a population of over 4.6 million and is therefore the most populous urban area in Germany. The Berlin/Brandenburg Metropolitan Region, Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Germany's second-largest metropolitan region after the Rhine-Ruhr region, as well as the List of EU metropolitan areas by GDP, fifth-biggest metropolitan region by GDP in the European Union. ...
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