DMPEA
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DMPEA
DMPEA can refer to two subclasses of substituted phenethylamines: Dimethoxy-phenethylamines * 2,3-Dimethoxyphenethylamine * 2,4-Dimethoxyphenethylamine * 2,5-Dimethoxyphenethylamine * 2,6-Dimethoxyphenethylamine * 3,4-Dimethoxyphenethylamine (homoveratrylamine) * 3,5-Dimethoxyphenethylamine Dimethyl-phenethylamines * α,α-Dimethylphenethylamine (Phentermine) * ''N'',α-Dimethylphenethylamine (Methamphetamine) * 2,α-Dimethylphenethylamine Ortetamine (INN), also known as 2-methylamphetamine, is a stimulant drug of the amphetamine class. In animal drug discrimination tests it substituted for dextroamphetamine more closely than either 3- or 4-methylamphetamine, although with only a ... (Ortetamine) * 3,α-Dimethylphenethylamine * 4,α-Dimethylphenethylamine * ''N'',''N''-Dimethylphenethylamine {{Chemistry index ...
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2,4-Dimethoxyphenethylamine
2,4-Dimethoxyphenethylamine (2,4-DMPEA), also known as DMPEA-3, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It is one of the positional isomers of dimethoxyphenethylamine. The ''in-vitro'' metabolism of 2,3-DMPEA and its effects on cat behavior have been studied. The drug is known to act as a low-potency partial agonist of the serotonin 5-HT2A receptor (Ki = 202–999nM; = 832–4,034nM; = 67–83%). The effects of 2,4-DMPEA in humans have not been reported and are unknown. 2,4-DMPEA was first described in the scientific literature by at least 1964. It was included as an entry in Alexander Shulgin's 2011 book '' The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds''. NBOMe and NBOH derivatives with potent serotonin 5-HT2A receptor agonism, such as 24-NBOMe and 24-NBOH, have been synthesized and studied. See also * Substituted methoxyphenethylamine * Dimethoxyphenethylamine Dim ...
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2,6-Dimethoxyphenethylamine
2,6-Dimethoxyphenethylamine (2,6-DMPEA), also known as DMPEA-5, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It is one of the positional isomers of dimethoxyphenethylamine. Its ''in-vitro'' metabolism and effects on cat behavior have been described. The drug showed no activity as a norepinephrine reuptake inhibitor or releasing agent ''in vitro''. It is relatively unaffected by monoamine oxidase (MAO) and is said to be behaviorally inactive in animals. The effects of 2,6-DMPEA in humans have not been reported and are unknown. 2,6-DMPEA was first described in the scientific literature by at least 1962. It was included as an entry in Alexander Shulgin's 2011 book '' The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds''. Notable derivatives of 2,6-DMPEA include the psychedelic and related drugs Ψ-2C-T-4 (psi-2C-T-4), ψ-DOM (psi-DOM), and CT-5172. See also * Substituted methoxyphene ...
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2,3-Dimethoxyphenethylamine
2,3-Dimethoxyphenethylamine (2,3-DMPEA), also known as DMPEA-2, is a drug of the phenethylamine family related to the psychedelic drug mescaline (3,4,5-trimethoxyphenethylamine). It is one of the positional isomers of dimethoxyphenethylamine. In contrast to various other phenethylamines like β-phenethylamine and amphetamine, it showed little activity in terms of induction of norepinephrine release ''in vitro''. The effects of 2,3-DMPEA in humans have not been reported and are unknown. 2,3-DMPEA was first described in the scientific literature by at least 1965. It was included as an entry in Alexander Shulgin's 2011 book '' The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds''. See also * Substituted methoxyphenethylamine * Dimethoxyphenethylamine Dimethoxyphenethylamine may refer to: * 2,3-Dimethoxyphenethylamine (2,3-DMPEA; DMPEA-2) * 2,4-Dimethoxyphenethylamine (2,4-DMPEA; DMPEA-3) * 2,5-Dimethoxyphenethylamine (2C-H; 2,5-DMPEA; DMPEA-4) * 2, ...
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3,5-Dimethoxyphenethylamine
3,5-Dimethoxyphenethylamine (3,5-DMPEA), also known as DMPEA-6 or as 4-desmethoxymescaline, is an alkaloid of the phenethylamine family related to mescaline (3,4,5-trimethoxymescaline). It naturally occurs in the cactus ''Pelecyphora aselliformis''. The effects of 3,5-DMPEA in humans are unknown. The compound may be considered the parent compound of the substituted mescaline analogues (4-substituted 3,5-dimethoxyphenethylamines or "scalines"). See also * Substituted methoxyphenethylamine * Dimethoxyphenethylamine Dimethoxyphenethylamine may refer to: * 2,3-Dimethoxyphenethylamine (2,3-DMPEA; DMPEA-2) * 2,4-Dimethoxyphenethylamine (2,4-DMPEA; DMPEA-3) * 2,5-Dimethoxyphenethylamine (2C-H; 2,5-DMPEA; DMPEA-4) * 2,6-Dimethoxyphenethylamine (2,6-DMPEA; DMPEA ... * 2,5-Dimethoxyphenethylamine (2,5-DMPEA; 2C-H) * 3,5-Dimethoxyamphetamine (3,5-DMA) References External links 3,5-DMPEA - Isomer Design Methoxyphenethylamines Phenethylamine alkaloids Scalines {{Alkalo ...
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2,5-Dimethoxyphenethylamine
2C-H, also known as 2,5-dimethoxyphenethylamine (2,5-DMPEA), is a lesser-known drug of the phenethylamine and 2C (4-substituted 2,5-dimethoxyphenethylamine) families. It is the parent compound of the 2C drugs. Use and effects There is no record of 2C-H trials in humans, as it would likely be destroyed by monoamine oxidase enzymes before causing any significant psychoactive effects. In the book ''PiHKAL'', Alexander Shulgin lists both the dosage and duration of 2C-H effects as unknown. Very little data exists about the pharmacological properties, metabolism, and toxicity of 2C-H. Pharmacology 2C-H acts as a partial agonist of the serotonin 5-HT2A, 5-HT2B, and 5-HT2C receptors, albeit with far lower potency than other 2C drugs. It also shows affinity for the serotonin 5-HT1A receptor, higher than that of any other 2C drug. The drug exhibits agonist activity ''in vitro'' at the human trace amine associated receptor 1 (TAAR1). 2C-H produces visual and auditory changes ...
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Substituted Phenethylamine
Substituted phenethylamines (or simply phenethylamines) are a chemical class of organic compounds that are based upon the phenethylamine structure; the class is composed of all the derivative (chemistry), derivative compounds of phenethylamine which can be formed by replacing, or substitution reaction, substituting, one or more hydrogen atoms in the phenethylamine core structure with substituents. Phenylethylamines are also generally found to be central nervous system stimulants with many also being entactogens/empathogens, and hallucinogens. Structural classification The structural formula of any substituted phenethylamine contains a phenyl group, phenyl ring that is joined to an amino group, amino (NH) group via a two-carbon substituent, sidechain. Hence, any substituted phenethylamine can be classified according to the substitution of hydrogen atom, hydrogen (H) atoms on phenethylamine's phenyl ring, sidechain, or amino group with a moiety (chemistry), specific group of at ...
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