2,3-Dimethoxyphenethylamine (2,3-DMPEA), also known as DMPEA-2, is a
drug
A drug is any chemical substance other than a nutrient or an essential dietary ingredient, which, when administered to a living organism, produces a biological effect. Consumption of drugs can be via insufflation (medicine), inhalation, drug i ...
of the
phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace ami ...
family related to the
psychedelic drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic halluc ...
mescaline
Mescaline, also known as mescalin or mezcalin, and in chemical terms 3,4,5-trimethoxyphenethylamine, is a natural product, naturally occurring psychedelic drug, psychedelic alkaloid, protoalkaloid of the substituted phenethylamine class, found ...
(3,4,5-trimethoxyphenethylamine).
It is one of the
positional isomer
In chemistry, a structural isomer (or constitutional isomer in the IUPAC nomenclature) of a compound is a compound that contains the same number and type of atoms, but with a different connectivity (i.e. arrangement of bonds) between them. The ...
s of
dimethoxyphenethylamine Dimethoxyphenethylamine may refer to:
* 2,3-Dimethoxyphenethylamine (2,3-DMPEA; DMPEA-2)
* 2,4-Dimethoxyphenethylamine (2,4-DMPEA; DMPEA-3)
* 2,5-Dimethoxyphenethylamine (2C-H; 2,5-DMPEA; DMPEA-4)
* 2,6-Dimethoxyphenethylamine (2,6-DMPEA; DMPEA ...
.
In contrast to various other phenethylamines like
β-phenethylamine
Phenethylamine (PEA) is an organic compound, natural monoamine alkaloid, and trace amine, which acts as a central nervous system stimulant in humans. In the brain, phenethylamine regulates monoamine neurotransmission by binding to trace ami ...
and
amphetamine
Amphetamine (contracted from Alpha and beta carbon, alpha-methylphenethylamine, methylphenethylamine) is a central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, an ...
, it showed little activity in terms of
induction of norepinephrine release ''
in vitro
''In vitro'' (meaning ''in glass'', or ''in the glass'') Research, studies are performed with Cell (biology), cells or biological molecules outside their normal biological context. Colloquially called "test-tube experiments", these studies in ...
''.
The effects of 2,3-DMPEA in humans have not been reported and are unknown.
2,3-DMPEA was first described in the
scientific literature
Scientific literature encompasses a vast body of academic papers that spans various disciplines within the natural and social sciences. It primarily consists of academic papers that present original empirical research and theoretical ...
by at least 1965.
It was included as an entry in
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and ph ...
's 2011 book ''
The Shulgin Index, Volume One: Psychedelic Phenethylamines and Related Compounds''.
See also
*
Substituted methoxyphenethylamine
Methoxyphenethylamines (MPEAs), as well as methoxyamphetamines (MAs) in the case of the amphetamine (α-methylphenethylamine) homologues, are substituted phenethylamines with one or more methoxy groups. In some cases, one or more of the methoxy ...
*
Dimethoxyphenethylamine Dimethoxyphenethylamine may refer to:
* 2,3-Dimethoxyphenethylamine (2,3-DMPEA; DMPEA-2)
* 2,4-Dimethoxyphenethylamine (2,4-DMPEA; DMPEA-3)
* 2,5-Dimethoxyphenethylamine (2C-H; 2,5-DMPEA; DMPEA-4)
* 2,6-Dimethoxyphenethylamine (2,6-DMPEA; DMPEA ...
*
2,3-Dimethoxyamphetamine
*
Isomescaline (2,3,4-trimethoxyphenethylamine)
References
External links
2,3-DMPEA - Isomer Design
{{DEFAULTSORT:Dimethoxyphenethylamine, 2,3-
Methoxyphenethylamines