Cellular Anastasis
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Cellular Anastasis
Anastasis is a cellular phenomenon characterized by recovery of cells threatened by cell death; it essentially reverses the process of programmed cell death, or apoptosis. Contrary to the prior assumption that apoptosis is irreversible, some cells have been discovered to resist the stimuli that trigger apoptosis. Some of these cells can survive even following the activation of Caspase#Apoptosis, executioner caspases, forming the basis of anastasis. The initial phase of recovery begins when Transcription (biology), transcription is initiated and the cell recovers from previous stressors. Finally, the cell's cytoskeleton undergoes reorganization, reinforcing its structure and encouraging Cell migration, migration. The relatively recent discovery of anastasis is a key factor in the survival of cancer cells exposed to chemotherapy and changed the way scientists approach the topic of cell death. Anastasis is possible even during advanced stages of cell death, leading researchers to believe ...
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Cell Death
Cell death is the event of a biological cell ceasing to carry out its functions. This may be the result of the natural process of old cells dying and being replaced by new ones, as in programmed cell death, or may result from factors such as diseases, localized injury, or the death of the organism of which the cells are part. Apoptosis or Type I cell-death, and Autophagy (cellular), autophagy or Type II cell-death are both forms of programmed cell death, while necrosis is a non-physiological process that occurs as a result of infection or injury. The term "cell necrobiology" has been used to describe the life processes associated with morphological, biochemical, and molecular changes which predispose, precede, and accompany cell death, as well as the consequences and tissue response to cell death. The word is derived from the Greek language, Greek νεκρό meaning "death", βìο meaning "life", and logos, λόγος meaning "the study of". The term was initially coined to bro ...
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Phagocyte
Phagocytes are cells that protect the body by ingesting harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek ', "to eat" or "devour", and "-cyte", the suffix in biology denoting "cell", from the Greek ''kutos,'' "hollow vessel". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae.Ilya Mechnikov
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''Physiology or Medicine 1901–192 ...
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HeLa Cells Stained With Antibody To Actin (green) , Vimentin (red) And DNA (blue)
HeLa () is an immortalized cell line used in scientific research. It is the oldest human cell line and one of the most commonly used. HeLa cells are durable and prolific, allowing for extensive applications in scientific study. The line is derived from cervical cancer cells taken on February 8, 1951, from Henrietta Lacks, a 31-year-old African American mother of five, after whom the line is named. Lacks died of cancer on October 4, 1951. The cells from Lacks's cancerous cervical tumor were taken without her knowledge, which was common practice in the United States at the time. Cell biologist George Otto Gey found that they could be kept alive, and developed a cell line. Previously, cells cultured from other human cells would survive for only a few days, but cells from Lacks's tumor behaved differently. History Origin In 1951, Henrietta Lacks was admitted to the Johns Hopkins Hospital with symptoms of irregular vaginal bleeding; she was subsequently treated for cervical ...
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Morphology (biology)
Morphology (from Ancient Greek μορφή (morphḗ) "form", and λόγος (lógos) "word, study, research") is the study of the form and structure of organisms and their specific structural features. This includes aspects of the outward appearance (shape, structure, color, pattern, size), as well as the form and structure of internal parts like bones and organs, i.e., anatomy. This is in contrast to physiology, which deals primarily with function. Morphology is a branch of life science dealing with the study of the overall structure of an organism or taxon and its component parts. History The etymology of the word "morphology" is from the Ancient Greek (), meaning "form", and (), meaning "word, study, research". While the concept of form in biology, opposed to function, dates back to Aristotle (see Aristotle's biology), the field of morphology was developed by Johann Wolfgang von Goethe (1790) and independently by the German anatomist and physiologist Karl Fried ...
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DNA Damage
DNA repair is a collection of processes by which a cell identifies and corrects damage to the DNA molecules that encode its genome. A weakened capacity for DNA repair is a risk factor for the development of cancer. DNA is constantly modified in cells, by internal metabolic by-products, and by external ionizing radiation, ultraviolet light, and medicines, resulting in spontaneous DNA damage involving tens of thousands of individual molecular lesions per cell per day. DNA modifications can also be programmed. Molecular lesions can cause structural damage to the DNA molecule, and can alter or eliminate the cell's ability for transcription and gene expression. Other lesions may induce potentially harmful mutations in the cell's genome, which affect the survival of its daughter cells following mitosis. Consequently, DNA repair as part of the DNA damage response (DDR) is constantly active. When normal repair processes fail, including apoptosis, irreparable DNA damage may occur ...
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Jesus
Jesus (AD 30 or 33), also referred to as Jesus Christ, Jesus of Nazareth, and many Names and titles of Jesus in the New Testament, other names and titles, was a 1st-century Jewish preacher and religious leader. He is the Jesus in Christianity, central figure of Christianity, the Major religious groups, world's largest religion. Most Christians consider Jesus to be the Incarnation (Christianity), incarnation of God the Son and awaited Messiah#Christianity, messiah, or Christ (title), Christ, a descendant from the Davidic line that is prophesied in the Old Testament. Virtually all modern scholars of classical antiquity, antiquity agree that Historicity of Jesus, Jesus existed historically. Accounts of Life of Jesus, Jesus's life are contained in the Gospels, especially the four canonical Gospels in the New Testament. Since the Age of Enlightenment, Enlightenment, Quest for the historical Jesus, academic research has yielded various views on the historical reliability of t ...
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Christianity
Christianity is an Abrahamic monotheistic religion, which states that Jesus in Christianity, Jesus is the Son of God (Christianity), Son of God and Resurrection of Jesus, rose from the dead after his Crucifixion of Jesus, crucifixion, whose coming as the Messiah#Christianity, messiah (Christ (title), Christ) was Old Testament messianic prophecies quoted in the New Testament, prophesied in the Old Testament and chronicled in the New Testament. It is the Major religious groups, world's largest and most widespread religion with over 2.3 billion followers, comprising around 28.8% of the world population. Its adherents, known as Christians, are estimated to make up a majority of the population in Christianity by country, 157 countries and territories. Christianity remains Christian culture, culturally diverse in its Western Christianity, Western and Eastern Christianity, Eastern branches, and doctrinally diverse concerning Justification (theology), justification and the natur ...
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Resurrection
Resurrection or anastasis is the concept of coming back to life after death. Reincarnation is a similar process hypothesized by other religions involving the same person or deity returning to another body. The disappearance of a body is another similar but distinct belief in some religions. With the advent of written records, the earliest known recurrent theme of resurrection was in Egyptian and Canaanite religions, which had cults of dying-and-rising gods such as Osiris and Baal. Ancient Greek religion generally emphasised immortality, but in the mythos, a number of individuals were made physically immortal as they were resurrected from the dead. The universal resurrection of the dead at the end of the world is a standard eschatological belief in the Abrahamic religions. As a religious concept, resurrection is used in two distinct respects: # a belief in the ''individual resurrections'' of individual souls that is current and ongoing (e.g., Christian idealism, realized e ...
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Greek Language
Greek (, ; , ) is an Indo-European languages, Indo-European language, constituting an independent Hellenic languages, Hellenic branch within the Indo-European language family. It is native to Greece, Cyprus, Italy (in Calabria and Salento), southern Albania, and other regions of the Balkans, Caucasus, the Black Sea coast, Asia Minor, and the Eastern Mediterranean. It has the list of languages by first written accounts, longest documented history of any Indo-European language, spanning at least 3,400 years of written records. Its writing system is the Greek alphabet, which has been used for approximately 2,800 years; previously, Greek was recorded in writing systems such as Linear B and the Cypriot syllabary. The Greek language holds a very important place in the history of the Western world. Beginning with the epics of Homer, ancient Greek literature includes many works of lasting importance in the European canon. Greek is also the language in which many of the foundational texts ...
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Alek Rapoport - Anastasis-1 - 1996
Alek is a given name and alternative form of Alec. Notable people with the name include: * Alek Bédard (born 1996), Canadian curler * Alek D. Epstein (born 1975), Russian-Israeli sociologist of culture and politics * Alek Dzhabrailov (1976–2009), Chechen human rights activist * Alek Keshishian (born 1964), Armenian-American film and commercial director, writer, and producer * Alek Manoah (born 1998), American baseball pitcher * Alek Manolov (born 1986), Bulgarian footballer * Alek Minassian (born 1992), Canadian murder suspect * Alek Osmanović (born 1982), Croatian bobsledder * Alek Popov (born 1966), Bulgarian novelist, writer, essayist and scriptwriter * Alek Rapoport (1933–1997), Russian Nonconformist artist, art theorist and teacher * Alek Sandar (born 1987), Bulgarian music producer, songwriter and recording artist * Alek Skarlatos (born 1992), American actor and US Army National Guard soldier * Alek Stojanov (born 1973), Canadian ice hockey player * Alek Thomas ...
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Ethanol
Ethanol (also called ethyl alcohol, grain alcohol, drinking alcohol, or simply alcohol) is an organic compound with the chemical formula . It is an Alcohol (chemistry), alcohol, with its formula also written as , or EtOH, where Et is the pseudoelement symbol for ethyl group, ethyl. Ethanol is a Volatility (chemistry), volatile, flammable, colorless liquid with a characteristic wine-like odor and pungent taste. As a psychoactive depressant, it is the active ingredient in alcoholic beverages, and the second most consumed drug globally behind caffeine. Ethanol is naturally produced by the fermentation process of sugars by yeasts or via petrochemical processes such as ethylene hydration. Historically it was used as a general anesthetic, and has modern medical applications as an antiseptic, disinfectant, solvent for some medications, and antidote for methanol poisoning and ethylene glycol poisoning. It is used as a chemical solvent and in the Chemical synthesis, synthesis of orga ...
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Breast Cancer
Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with Metastatic breast cancer, distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a Sedentary lifestyle, lack of physical exercise, alcohol consumption, hormone replacement therapy during menopause, ionizing radiation, an early age at Menarche, first menstruation, having children late in life (or not at all), older age, having a prior history of breast cancer, and a family history of breast cancer. About five to ten percent of cases are the result of an inherited genetic predisposition, including BRCA mutation, ''BRCA'' mutations among others. Breast ...
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