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Adam Ruben
Adam Ruben is an American writer, comedian, rapper, storyteller, science communicator, and molecular biologist. Ruben is known for hosting the show ''Outrageous Acts of Science'' on the Science Channel, known outside the United States as ''You Have Been Warned'' and ''Loco Lab''. He has also appeared on the Food Network's ''Food Detectives'', the Science Channel's '' Head Rush'', the Weather Channel's ''Weather Gone Viral'', the Travel Channel's ''Mysteries at the Kremlin'', Discovery International's ''Superhuman Science'', the Science Channel's ''How Do They Do It?'', the documentary ''Mortified Nation'', and NPR's ''All Things Considered'' and '' The Moth Radio Hour''. He is the author of ''Surviving Your Stupid, Stupid Decision to Go to Grad School'' (Random House, 2010), a satirical guide to post-baccalaureate education, and ''Pinball Wizards: Jackpots, Drains, and the Cult of the Silver Ball'' (Chicago Review Press, 2017), a narrative nonfiction book about the past, present, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Outrageous Acts Of Science
''Outrageous Acts of Science'' is a science program shown on Science Channel in the U.S., featuring a fast-paced countdown of the top 20 internet videos in each episode. The series first aired in the UK on Discovery International with the title ''You Have Been Warned''. The program features homemade science experiments and stunts, often accompanied by warnings of "don't try this at home" when doing so might endanger the viewer. For the U.S. TV network, it was the top-rated show of 2015. Each episode focuses on a particular science theme that features the cleverest, funniest, most daring, or just downright bizarre clips, along with an explanation and breakdown from science and engineering experts, including Hakeem Oluseyi, Debbie Berebichez, Carin Bondar and also-comedians Helen Arney, Matt Parker, Adam Ruben, and Tom Wrigglesworth, among others. The expert panel's explanations are accompanied with storytelling motion graphics and an explanation of what, how and why these clips ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Presidential Scholars Program
The United States Presidential Scholars Program is a program of the United States Department of Education. It is described as "one of the Nation's highest honors for students" in the United States of America and the globe. The program was established in 1964 by Executive Order of the President of the United States to recognize the most distinguished graduating seniors for their accomplishments in many areas: academic success, leadership, and service to school and community. In 1979, it was expanded to recognize students who demonstrate exceptional scholarship and talent in the visual, creative, and performing arts. In 2015, the program was expanded once again to recognize students who demonstrate ability and accomplishment in career and technical fields. In the recent past, the organization has welcomed nominations from individual recommenders of the students' own choosing regardless of whether these students' academic results or achievements otherwise qualified them for recognit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemoglobin
Hemoglobin (haemoglobin BrE) (from the Greek word αἷμα, ''haîma'' 'blood' + Latin ''globus'' 'ball, sphere' + ''-in'') (), abbreviated Hb or Hgb, is the iron-containing oxygen-transport metalloprotein present in red blood cells (erythrocytes) of almost all vertebrates (the exception being the fish family Channichthyidae) as well as the tissues of some invertebrates. Hemoglobin in blood carries oxygen from the respiratory organs (''e.g.'' lungs or gills) to the rest of the body (''i.e.'' tissues). There it releases the oxygen to permit aerobic respiration to provide energy to power functions of an organism in the process called metabolism. A healthy individual human has 12to 20grams of hemoglobin in every 100mL of blood. In mammals, the chromoprotein makes up about 96% of the red blood cells' dry content (by weight), and around 35% of the total content (including water). Hemoglobin has an oxygen-binding capacity of 1.34mL O2 per gram, which increases the total blood oxygen ca ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasmodium Falciparum
''Plasmodium falciparum'' is a unicellular protozoan parasite of humans, and the deadliest species of ''Plasmodium'' that causes malaria in humans. The parasite is transmitted through the bite of a female '' Anopheles'' mosquito and causes the disease's most dangerous form, falciparum malaria. It is responsible for around 50% of all malaria cases. ''P. falciparum'' is therefore regarded as the deadliest parasite in humans. It is also associated with the development of blood cancer (Burkitt's lymphoma) and is classified as a Group 2A (probable) carcinogen. The species originated from the malarial parasite '' Laverania'' found in gorillas, around 10,000 years ago. Alphonse Laveran was the first to identify the parasite in 1880, and named it ''Oscillaria malariae''. Ronald Ross discovered its transmission by mosquito in 1897. Giovanni Battista Grassi elucidated the complete transmission from a female anopheline mosquito to humans in 1898. In 1897, William H. Welch created the n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Malaria
Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. Symptoms usually begin ten to fifteen days after being bitten by an infected mosquito. If not properly treated, people may have recurrences of the disease months later. In those who have recently survived an infection, reinfection usually causes milder symptoms. This partial resistance disappears over months to years if the person has no continuing exposure to malaria. Malaria is caused by single-celled microorganisms of the '' Plasmodium'' group. It is spread exclusively through bites of infected '' Anopheles'' mosquitoes. The mosquito bite introduces the parasites from the mosquito's saliva into a person's blood. The parasites travel to the liver where they mature and reproduce. Five species of ''Plasmodium'' can infect and be spr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aspartic Protease
Aspartic proteases are a catalytic type of protease enzymes that use an activated water molecule bound to one or more aspartate residues for catalysis of their peptide substrates. In general, they have two highly conserved aspartates in the active site and are optimally active at acidic pH. Nearly all known aspartyl proteases are inhibited by pepstatin. Aspartic endopeptidases of vertebrate, fungal and retroviral origin have been characterised. More recently, aspartic endopeptidases associated with the processing of bacterial type 4 prepilin and archaean preflagellin have been described. Eukaryotic aspartic proteases include pepsins, cathepsins, and renins. They have a two-domain structure, arising from ancestral duplication. Retroviral and retrotransposon proteases (retroviral aspartyl proteases) are much smaller and appear to be homologous to a single domain of the eukaryotic aspartyl proteases. Each domain contributes a catalytic Asp residue, with an extended active ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasmepsin
Plasmepsins are a class of at least 10 enzymes ( and ) produced by the ''Plasmodium falciparum'' parasite. There are ten different isoforms of these proteins and ten genes coding them respectively in ''Plasmodium'' (Plm I, II, III, IV, V, VI, VII, IX, X and HAP). It has been suggested that the plasmepsin family is smaller in other human ''Plasmodium'' species. Expression of Plm I, II, IV, V, IX, X and HAP occurs in the erythrocytic cycle, and expression of Plm VI, VII, VIII, occurs in the exoerythrocytic cycle. Through their haemoglobin-degrading activity, they are an important cause of symptoms in malaria sufferers. Consequently, this family of enzymes is a potential target for antimalarial drugs. Plasmepsins are aspartic acid proteases, meaning their active site contains two aspartic acid residues. These two aspartic acid residue act respectively as proton donor and proton acceptor, catalysing the hydrolysis of peptide bond in proteins. There are four types of plasmepsins, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spectrophotometry
Spectrophotometry is a branch of electromagnetic spectroscopy concerned with the quantitative measurement of the reflection or transmission properties of a material as a function of wavelength. Spectrophotometry uses photometers, known as spectrophotometers, that can measure the intensity of a light beam at different wavelengths. Although spectrophotometry is most commonly applied to ultraviolet, visible, and infrared radiation, modern spectrophotometers can interrogate wide swaths of the electromagnetic spectrum, including x-ray, ultraviolet, visible, infrared, and/or microwave wavelengths. Overview Spectrophotometry is a tool that hinges on the quantitative analysis of molecules depending on how much light is absorbed by colored compounds. Important features of spectrophotometers are spectral bandwidth (the range of colors it can transmit through the test sample), the percentage of sample-transmission, the logarithmic range of sample-absorption, and sometimes a percenta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isothermal Titration Calorimetry
Isothermal titration calorimetry (ITC) is a physical technique used to determine the thermodynamic parameters of interactions in solution. It is most often used to study the binding of small molecules (such as medicinal compounds) to larger macromolecules (proteins, DNA etc.). It consists of two cells which are enclosed in an adiabatic jacket. The compounds to be studied are placed in the sample cell, while the other cell, the reference cell, is used as a control and contains the buffer in which the sample is dissolved. Thermodynamic measurements ITC is a quantitative technique that can determine the binding affinity (K_a), enthalpy changes (\Delta H), and binding stoichiometry (n) of the interaction between two or more molecules in solution. From these initial measurements, Gibbs free energy changes (\Delta G) and entropy changes (\Delta S) can be determined using the relationship: :::\Delta G = -RT\ln = \Delta H -T\Delta S (where R is the gas constant and T is the absolute ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baltimore
Baltimore ( , locally: or ) is the List of municipalities in Maryland, most populous city in the U.S. state of Maryland, fourth most populous city in the Mid-Atlantic (United States), Mid-Atlantic, and List of United States cities by population, the 30th most populous city in the United States with a population of 585,708 in 2020. Baltimore was designated an Independent city (United States), independent city by the Constitution of Maryland in 1851, and today is the most populous independent city in the United States. As of 2021, the population of the Baltimore metropolitan area was estimated to be 2,838,327, making it the List of metropolitan areas of the United States, 20th largest metropolitan area in the country. Baltimore is located about north northeast of Washington, D.C., making it a principal city in the Washington–Baltimore combined statistical area, Washington–Baltimore combined statistical area (CSA), the third-largest combined statistical area, CSA in the nat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins University
Johns Hopkins University (Johns Hopkins, Hopkins, or JHU) is a private research university in Baltimore, Maryland. Founded in 1876, Johns Hopkins is the oldest research university in the United States and in the western hemisphere. It consistently ranks among the most prestigious universities in the United States and the world. The university was named for its first benefactor, the American entrepreneur and Quaker philanthropist Johns Hopkins. Hopkins' $7 million bequest to establish the university was the largest philanthropic gift in U.S. history up to that time. Daniel Coit Gilman, who was inaugurated as Johns Hopkins's first president on February 22, 1876, led the university to revolutionize higher education in the U.S. by integrating teaching and research. In 1900, Johns Hopkins became a founding member of the American Association of Universities. The university has led all U.S. universities in annual research expenditures over the past three decades. Johns Hopkins is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Princeton Triangle Club
The Princeton Triangle Club is a theater troupe at Princeton University. Founded in 1891, it is one of the oldest collegiate theater troupes in the United States. Triangle premieres an original student-written musical every year, and then takes that show on a national tour. The club is known for its signature kickline; historically performed by the men of the ensemble in drag, the kickline has recently featured both all-female and co-ed casts. The troupe presents several shows throughout the year. In September at the end of the University's Freshman Week, the Club presents its "Frosh Week Show", a revue of popular material from previous years. In the autumn it premieres the year's new Triangle Show, an original student-written musical comedy, professionally directed and choreographed and performed in McCarter Theatre; this Triangle Show goes on a national tour in January. In spring, the Club showcases the new writers' material in a smaller campus venue. And during reunions af ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
