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3,4-Difluoroamphetamine
3,4-Difluoroamphetamine (DFA) is a substituted amphetamine which has been sold as a designer drug. It has relatively weak activity as a serotonin releasing agent with only around 1/4 of the affinity for the serotonin transporter compared to MDA, but its activity at other targets has not been studied. See also * 3-Fluoroamphetamine * 3-Fluoromethamphetamine * 4-Fluoroamphetamine * 4-Fluoromethamphetamine * 3,5-Difluoromethcathinone * DFMDA * DODC DODC is a psychedelic drug from the substituted amphetamine family which acts as an agonist of the 5-HT2A receptor. It is the 3,4-dichloro derivative of the well known psychedelic drug 2,5-Dimethoxy-4-chloroamphetamine (DOC). DODC was first off ... * Xylopropamine References Designer drugs Serotonin-norepinephrine-dopamine releasing agents Fluoroarenes Amines {{nervous-system-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
4-Fluoroamphetamine
4-Fluoroamphetamine (4-FA; 4-FMP; PAL-303; "Flux"), also known as ''para''-fluoroamphetamine (PFA) is a psychoactive drug, psychoactive research chemical of the phenethylamine and substituted amphetamine chemical classes. It produces stimulant and entactogenic effects. As a recreational drug, 4-FA is sometimes sold along with related compounds such as 2-fluoroamphetamine and 4-fluoromethamphetamine. Usage 4-FA is popular in the Netherlands where it is predominantly used for its specific effects (77% of users) rather than its legal status (18%). 4-FA has become illegal since May 2017. Effects The subjective effects of 4-fluoroamphetamine include euphoria which some find similar to the effects of MDMA and amphetamine, increased energy (stimulation), mood elevation, feelings of warmth and empathy, excessive talking, bruxism, and suppressed appetite (anorexic). The general course of effects involves primarily empathogenic effects for the first few hours, which fades out as increa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Xylopropamine
Xylopropamine (Perhedrin, Esanin), also known as 3,4-dimethylamphetamine, is a stimulant drug of the phenethylamine and amphetamine classes which was developed and marketed as an appetite suppressant in the 1950s. Xylopropamine was briefly sold as the sulfate salt, but it was not widely marketed. Other related amphetamine derivatives such as 2,4-dimethylamphetamine were also investigated for the same purpose, however these drugs had negative side effects such as high blood pressure and were not very successful, mainly due to the introduction of alternative drugs like phentermine which had similar efficacy but fewer side effects. Xylopropamine was also reported as having analgesic and anti-inflammatory effects but its side effect profile resulted in it never being further developed for these applications. See also * Methamphetamine * Dimethylamphetamine * 3,4-Dimethylphenethylamine * 3,4-Dimethylmethcathinone * 3,4-Difluoroamphetamine * 4-Methylamphetamine * 4-Methylmethamphe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DODC
DODC is a psychedelic drug from the substituted amphetamine family which acts as an agonist of the 5-HT2A receptor. It is the 3,4-dichloro derivative of the well known psychedelic drug 2,5-Dimethoxy-4-chloroamphetamine (DOC). DODC was first officially published in a patent filed by Gilgamesh Pharmaceuticals in 2020, though anecdotal reports suggest it had been synthesised by clandestine chemists and its activity established several years prior to this. See also * DOx * Ganesha (psychedelic) * DMMDA * 2,3,4,5-Tetramethoxyamphetamine * 3,4-Difluoroamphetamine * CT-5172 CT-5172, also known as 2,6-dimethoxy-3,5-dichlorophenethylamine, is a claimed hallucinogen of the phenethylamine family. It is an analogue of the serotonergic psychedelics mescaline and the 2C series but with an unusual substitution pattern on t ... References Designer drugs DOx (psychedelics) Methoxy compounds Psychedelic phenethylamines Serotonin receptor agonists {{hallucinogen-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3,5-Difluoromethcathinone
3,5-Difluoromethcathinone (also known as 3,5-DFMC) is a chemical compound from the cathinone family that has been sold as a designer drug, first being identified in Australia in 2009. Legal status In the United Kingdom, 3,5-DFMC is a controlled drug under the cathinone blanket ban. 3,5-DFMC is an Anlage II controlled drug in Germany. See also * 3-Fluoroamphetamine * 3-Fluoroethamphetamine * 3-Fluoromethamphetamine * 3-Fluoromethcathinone * 3,4-Difluoroamphetamine * Manifaxine * Substituted cathinone Substituted cathinones, or simply cathinones, which include some stimulants and Empathogen-entactogen, entactogens, are chemical derivative, derivatives of cathinone. They feature a substituted phenethylamine, phenethylamine core with an alkyl ... References {{DEFAULTSORT:Difluoromethcathinone, 3,5- Cathinones Designer drugs Fluoroarenes Norepinephrine-dopamine releasing agents ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Designer Drugs
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Designer drugs include psychoactive substances that have been designated by the European Union, Australia, and New Zealand, as new psychoactive substances (NPS) as well as analogs of performance-enhancing drugs such as designer steroids. Some of these designer drugs were originally synthesized by academic or industrial researchers in an effort to discover more potent derivatives with fewer side effects and shorter duration (and possibly also because it is easier to apply for patents for new molecules) and were later co-opted for recreational use. Other designer drugs were prepared for the first time in clandestine laboratories. Because the efficacy and safety of these substances have not been thoroughly evaluated in animal and human tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DFMDA
Difluoromethylenedioxyamphetamine (DFMDA, DiFMDA) is a substituted derivative of 3,4-methylenedioxyamphetamine (MDA), which was developed by Daniel Trachsel and coworkers, along with the corresponding fluorinated derivatives of MDMA, MDEA, BDB and MBDB, with the aim of finding a non-neurotoxic drug able to be used as a less harmful substitute for entactogenic drugs such as MDMA. Since a major route of the normal metabolism of these compounds is scission of the methylenedioxy ring, producing neurotoxic metabolites such as alpha-methyldopamine, it was hoped that the difluoromethylenedioxy bioisostere would show increased metabolic stability and less toxicity. These compounds have not yet been tested in animals to verify whether they show similar pharmacological activity to the non-fluorinated parent compounds, although ''in vitro'' binding studies show DFMDA to have a SERT affinity in between that of MDA and MDMA. It is also now generally accepted that MDMA neurotoxicity results ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituted Amphetamine
Substituted amphetamines, or simply amphetamines, are a chemical class, class of compounds based upon the amphetamine structure; it includes all derivative (chemistry), derivative compounds which are formed by replacing, or substitution reaction, substituting, one or more hydrogen atoms in the amphetamine core structure with substituents. The compounds in this class span a variety of pharmacological subclasses, including stimulants, Empathogen-entactogen, empathogens, and hallucinogens, among others. Examples of substituted amphetamines are amphetamine (itself), methamphetamine, ephedrine, cathinone, phentermine, mephentermine, tranylcypromine, bupropion, methoxyphenamine, selegiline, amfepramone, amfepramone (diethylpropion), pyrovalerone, MDMA (ecstasy), and 2,5-dimethoxy-4-methylamphetamine, DOM (STP). Some of amphetamine's substituted Derivative (chemistry), derivatives occur in nature, for example in the leaves of ''Ephedra (genus), Ephedra'' and khat plants. Amphetamine w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Designer Drug
A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. Designer drugs include psychoactive substances that have been designated by the European Union, Australia, and New Zealand, as new psychoactive substances (NPS) as well as analogs of performance-enhancing drugs such as designer steroids. Some of these designer drugs were originally synthesized by academic or industrial researchers in an effort to discover more potent derivatives with fewer side effects and shorter duration (and possibly also because it is easier to apply for patents for new molecules) and were later co-opted for recreational use. Other designer drugs were prepared for the first time in clandestine laboratories. Because the efficacy and safety of these substances have not been thoroughly evaluated in animal and human tr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
3-Fluoromethamphetamine
3-Fluoromethamphetamine (3-FMA) is a stimulant drug related to methamphetamine and 3-fluoroamphetamine. It has been sold online as a designer drug. Legal status Canada As of 1996, 3-FMA is a controlled substance in Canada, due to being an analog of methamphetamine. China As of October 2015, 3-FMA is a controlled substance in China. United States As a close analog of scheduled controlled substance, sale or possession of 3-FMA could be potentially be prosecuted under the Federal Analogue Act. See also * 2-Fluoroamphetamine * 2-Fluoromethamphetamine * 3-Fluoroamphetamine * 3-Fluoroethamphetamine * 3-Fluoromethcathinone * 4-Fluoroamphetamine * 4-Fluoromethamphetamine * 3-Chloromethamphetamine 3-Chloromethamphetamine (3-CMA, MCMA) is a substituted amphetamine derivative invented in the 1960s. In animal studies it was deemed to be a "hallucinogen" rather than a stimulant, though the assays used at the time did not distinguish between th ... References Desig ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
