3,4-Difluoroamphetamine (DFA) is a

substituted amphetamine Substituted amphetamines, or simply amphetamines, are a chemical class, class of compounds based upon the amphetamine structure; it includes all derivative (chemistry), derivative compounds which are formed by replacing, or substitution reacti ...

which has been sold as a

designer drug A designer drug is a structural or functional analog of a controlled substance that has been designed to mimic the pharmacological effects of the original drug, while avoiding classification as illegal and/or detection in standard drug tests. ...

. It has relatively weak activity as a

serotonin releasing agent A serotonin releasing agent (SRA) is a type of drug that induces the release of serotonin into the neuronal synaptic cleft. A selective serotonin releasing agent (SSRA) is an SRA with less significant or no efficacy in producing neurotransmitter ...

with only around 1/4 of the

affinity Affinity may refer to: Commerce, finance and law * Affinity (law), kinship by marriage * Affinity analysis, a market research and business management technique * Affinity Credit Union, a Saskatchewan-based credit union * Affinity Equity Pa ...

for the

serotonin transporter The serotonin transporter (SERT or 5-HTT) also known as the sodium-dependent serotonin transporter and solute carrier family 6 member 4 is a protein that in humans is encoded by the SLC6A4 gene. SERT is a type of monoamine transporter protein t ...

compared to

MDA MDA, mda or variants may refer to: Businesses and organizations Political parties * Meghalaya Democratic Alliance (2003–2008), in India * Meghalaya Democratic Alliance (2018–present), in India * Movement for Democracy in Africa, in Burkina F ...

, but its activity at other targets has not been studied.

References

Designer drugs Serotonin-norepinephrine-dopamine releasing agents Fluoroarenes Amines {{nervous-system-drug-stub

See also

References