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3,4-Dichloro-1,2,5-thiadiazole
3,4-Dichloro-1,2,5-thiadiazole is the heterocycle with the formula . It is a colorless liquid. The compound is produced by treating cyanogen with disulfur dichloride. The compound can also be prepared from aminoacetonitrile. It is a planar molecule consisting of a thiadiazole core with two chlorine atoms as substituents. The chloride groups are displaced readily by ammonia to give the diamine: : Related compounds * 2,1,3-Benzothiadiazole, , derived from 1,2-diaminobenzene ''o''-Phenylenediamine (OPD) is an organic compound with the formula C6H4(NH2)2. This aromatic diamine is an important precursor to many heterocyclic compounds. OPD is a white compound although samples appear darker owing to oxidation by air. I ... References {{DEFAULTSORT:Dichloro-1,2,5-thiadiazole, 3,4- Thiadiazoles Chloroarenes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cyanogen
Cyanogen is the chemical compound with the chemical formula, formula . Its structure is . The simplest stable carbon nitride, it is a Transparency and translucency, colorless and highly toxic gas with a pungency, pungent odor. The molecule is a pseudohalogen. Cyanogen molecules are linear molecular geometry, linear, and consist of two CN groups ‒ analogous to diatomic halogen molecules, such as chlorine, Cl, but far less oxidizing. The two cyanide, cyano groups are bonded together at their carbon atoms, though other isomers have been detected. The name is also used for the CN radical, and hence is used for compounds such as cyanogen bromide () (but see also ''Cyano radical''). When burned at increased pressure with oxygen, it is possible to get a blue tinted flame, the temperature of which is about 4800°C (a higher temperature is possible with ozone). It is as such regarded as the gas with the second highest temperature of burning (after dicyanoacetylene). Cyanogen is the anhy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thiadiazole
In chemistry, thiadiazoles are a sub-family of azole compounds, with the name ''thiadiazole'' originating from the Hantzsch–Widman nomenclature. Structurally, they are five-membered heterocyclic compounds containing one sulfur and two nitrogen atoms. The ring is aromatic by virtue of the two double bonds and one of the lone pairs of electrons of sulfur. Four constitutional isomers are possible, differing by the relative positions of the sulfur and nitrogen atoms. The nomenclature thus includes the locations of each of those three atoms, with the first of the three numbers referring to the sulfur. The parent compounds are rarely synthesized and possess no particular application, however, compounds bearing them as a structural motif are fairly common in pharmacology. Of them, 1,3,4-thiadiazole is the most common, appearing in such medications as cephazolin and acetazolamide. 3,4-Dichloro-1,2,5-thiadiazole arises readily from cyanogen. In the Hurd–Mori reaction, an acyl hy ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Thiadiazoles
In chemistry, thiadiazoles are a sub-family of azole compounds, with the name ''thiadiazole'' originating from the Hantzsch–Widman nomenclature. Structurally, they are five-membered heterocyclic compounds containing one sulfur and two nitrogen atoms. The ring is Aromaticity, aromatic by virtue of the two double bonds and one of the lone pairs of electrons of sulfur. Four constitutional isomers are possible, differing by the relative positions of the sulfur and nitrogen atoms. The nomenclature thus includes the locations of each of those three atoms, with the first of the three numbers referring to the sulfur. The parent compounds are rarely synthesized and possess no particular application, however, compounds bearing them as a structural motif are fairly common in pharmacology. Of them, 1,3,4-thiadiazole is the most common, appearing in such medications as cephazolin and acetazolamide. 3,4-Dichloro-1,2,5-thiadiazole arises readily from cyanogen. In the Hurd–Mori reaction, an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heterocycle
A heterocyclic compound or ring structure is a cyclic compound that has atoms of at least two different elements as members of its ring(s). Heterocyclic organic chemistry is the branch of organic chemistry dealing with the synthesis, properties, and applications of organic heterocycles. Examples of heterocyclic compounds include all of the nucleic acids, the majority of drugs, most biomass (cellulose and related materials), and many natural and synthetic dyes. More than half of known compounds are heterocycles. 59% of US FDA-approved drugs contain nitrogen heterocycles. Classification The study of organic heterocyclic chemistry focuses especially on organic unsaturated derivatives, and the preponderance of work and applications involves unstrained organic 5- and 6-membered rings. Included are pyridine, thiophene, pyrrole, and furan. Another large class of organic heterocycles refers to those fused to benzene rings. For example, the fused benzene derivatives of p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Disulfur Dichloride
Disulfur dichloride (or disulphur dichloride by the British English spelling) is the inorganic compound of sulfur and chlorine with the Chemical formula, formula . It is an amber oily liquid. Sometimes, this compound is incorrectly named ''sulfur monochloride'' (or ''sulphur monochloride'' by the British English spelling), the name implied by its empirical formula SCl. has the structure implied by the formula , wherein the dihedral angle between the and planes is 85.2°. This structure is referred to as Conformational isomerism, gauche, and is akin to that for Hydrogen peroxide, . A rare isomer of is (thiothionyl chloride); this isomer forms transiently when is exposed to UV-radiation (see thiosulfoxides). Synthesis, basic properties, reactions Disulfur dichloride is a yellow liquid that fumes in moist air due to reaction with water: : It is produced by partial chlorination of elemental sulfur. The reaction proceeds at usable rates at room temperature. In the laboratory, c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aminoacetonitrile
Aminoacetonitrile is the organic compound with the formula . The compound is a colorless liquid. It is unstable at room temperature, owing to the incompatibility of the amine nucleophile and the nitrile electrophile. For this reason it is usually encountered as the chloride and bisulfate salts of the ammonium derivative, i.e., CCH2NH3sup>+Cl− and CCH2NH3sup>+HSO4−. Production and applications Industrially aminoacetonitrile is produced from glycolonitrile by reaction with ammonia: :HOCH2CN + NH3 → H2NCH2CN + H2O The aminoacetonitrile can be hydrolysed to give glycine: Being bifunctional, it is useful in the synthesis of diverse nitrogen-containing heterocycles. Aminoacetonitrile derivatives are useful antihelmintics. They act as nematode specific ACh agonists causing a spastic paralysis and rapid expulsion from the host. Occurrence in the interstellar medium Using radio astronomy, aminoacetonitrile was discovered in the Large Molecule Heimat, a giant gas cloud ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chlorine
Chlorine is a chemical element; it has Symbol (chemistry), symbol Cl and atomic number 17. The second-lightest of the halogens, it appears between fluorine and bromine in the periodic table and its properties are mostly intermediate between them. Chlorine is a yellow-green gas at room temperature. It is an extremely reactive element and a strong oxidizing agent, oxidising agent: among the elements, it has the highest electron affinity and the third-highest electronegativity on the revised Electronegativity#Pauling electronegativity, Pauling scale, behind only oxygen and fluorine. Chlorine played an important role in the experiments conducted by medieval Alchemy, alchemists, which commonly involved the heating of chloride Salt (chemistry), salts like ammonium chloride (sal ammoniac) and sodium chloride (common salt), producing various chemical substances containing chlorine such as hydrogen chloride, mercury(II) chloride (corrosive sublimate), and . However, the nature of fre ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Substituent
In organic chemistry, a substituent is one or a group of atoms that replaces (one or more) atoms, thereby becoming a moiety in the resultant (new) molecule. The suffix ''-yl'' is used when naming organic compounds that contain a single bond replacing one hydrogen; ''-ylidene'' and ''-ylidyne'' are used with double bonds and triple bonds, respectively. In addition, when naming hydrocarbons that contain a substituent, positional numbers are used to indicate which carbon atom the substituent attaches to when such information is needed to distinguish between isomers. Substituents can be a combination of the inductive effect and the mesomeric effect. Such effects are also described as electron-rich and electron withdrawing. Additional steric effects result from the volume occupied by a substituent. The phrases ''most-substituted'' and ''least-substituted'' are frequently used to describe or compare molecules that are products of a chemical reaction. In this terminology, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2,1,3-Benzothiadiazole
2,1,3-Benzothiadiazole is a bicyclic molecule composed of a benzene ring that is fused-ring compound, fused to a thiadiazoles, 1,2,5-thiadiazole. Preparation and structure 2,1,3-Benzothiadiazole has been known since the 19th century. It is readily prepared in at least 85% yield from o-Phenylenediamine, ''o''-phenylenediamine by reaction with two Equivalent (chemistry), equivalents of thionyl chloride in pyridine. The by-products are sulfur dioxide and HCl. : There are a number of alternative methods used to make this heterocycle and these have been reviewed. The crystal structure of the compound was determined in 1951, when it had the common name piazthiol(e). Reactions The extent of the aromaticity of the compound was examined by a study of its proton nuclear magnetic resonance, NMR spectrum and comparison with naphthalene, which allowed the conclusion that it and related oxygen and selenium heterocycles did behave as 10-electron systems in which the 2-heteroatom contribute ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1,2-Diaminobenzene
''o''-Phenylenediamine (OPD) is an organic compound with the formula C6H4(NH2)2. This aromatic diamine is an important precursor to many heterocyclic compounds. OPD is a white compound although samples appear darker owing to oxidation by air. It is isomeric with M-Phenylenediamine, ''m''-phenylenediamine and P-Phenylenediamine, ''p''-phenylenediamine. Preparation Commonly, 2-nitrochlorobenzene is treated with ammonia to generate 2-nitroaniline, whose Nitro compound, nitro group is then Redox, reduced: :ClC6H4NO2 + 2 NH3 → H2NC6H4NO2 + NH4Cl :H2NC6H4NO2 + 3 H2 → H2NC6H4NH2 + 2 H2O In the laboratory, the reduction of the nitroaniline is effected with zinc powder in ethanol, followed by purification of the diamine as the Hydrochloride, hydrochloride salt. Darkened impure samples can be purified by treatment of its aqueous solution with sodium dithionite and activated carbon. Reactions and uses ''o''-Phenylenediamine Condensation reaction, condenses with ketones and aldehyde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
