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Özlem Türeci
Özlem Türeci (; born 6 March 1967) is a German physician, scientist and entrepreneur. In 2008, she co-founded the biotechnology company BioNTech, which in 2020 developed the first messenger RNA-based vaccine approved for use against Coronavirus disease 2019, COVID-19. Türeci has served as BioNTech's chief medical officer since 2018. Since 2021, she has been Professor of Personalized Immunotherapy at the Helmholtz Institute for Translational Oncology (HI-TRON) and University of Mainz, Johannes Gutenberg University Mainz. Türeci and her spouse, Uğur Şahin, have won a number of awards. Personal life and education Born in Siegen, West Germany in 1967, Türeci is the daughter of Turkish immigrants. Her mother was a biologist. Her father, a surgeon, was from Istanbul and worked at the Catholic hospital St. Elisabeth-Stift in Lastrup in the district of Cloppenburg. She attended, among others, the Städtisches Gymnasium in Bad Driburg and the Werner-von-Siemens-Gymnasium in Bad Ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Siegen
Siegen () is a List of cities and towns in Germany, city in Germany, in the south Westphalian part of North Rhine-Westphalia. It is located in the district of Siegen-Wittgenstein in the Arnsberg (region), Arnsberg region. The university town (nearly 20,000 students in the 2018–2019 winter semester) is the district seat, and is ranked as a "higher centre" in the South Westphalian urban agglomeration. In 1975, municipal reforms and amalgamations lifted Siegen's population above the 100,000 mark. Geography Location The city of Siegen lies in the basin of the upper reaches of the river Sieg (river), Sieg. From there, lateral valleys branch off in many directions. The heights of the surrounding mountains, wherever they are not actually settled, are covered in Coppicing, coppice. To the north lies the Sauerland, to the northwest the Rothaargebirge and to the southwest the Westerwald. The nearest cities to Siegen, taking into account average travelling distances, are Hagen to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Surgeon
In medicine, a surgeon is a medical doctor who performs surgery. Even though there are different traditions in different times and places, a modern surgeon is a licensed physician and received the same medical training as physicians before specializing in surgery. In some countries and jurisdictions, the title of 'surgeon' is restricted to maintain the integrity of the craft group in the medical profession. A specialist regarded as a legally recognized surgeon includes podiatry, dentistry, and veterinary medicine. It is estimated that surgeons perform over 300 million surgical procedures globally each year. History The first person to document a surgery was the 6th century BC Indian physician-surgeon, Sushruta. He specialized in cosmetic plastic surgery and even documented an open rhinoplasty procedure.Papel, Ira D. and Frodel, John (2008) ''Facial Plastic and Reconstructive Surgery''. Thieme Medical Pub. His Masterpiece, magnum opus ''Suśruta-saṃhitā'' is one of the m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Habilitation
Habilitation is the highest university degree, or the procedure by which it is achieved, in Germany, France, Italy, Poland and some other European and non-English-speaking countries. The candidate fulfills a university's set criteria of excellence in research, teaching, and further education, which usually includes a dissertation. The degree, sometimes abbreviated ''Dr. habil''. (), ''dr hab.'' (), or ''D.Sc.'' ('' Doctor of Sciences'' in Russia and some CIS countries), is often a qualification for full professorship in those countries. In German-speaking countries it allows the degree holder to bear the title ''PD'' (for ). In a number of countries there exists an academic post of docent, appointment to which often requires such a qualification. The degree conferral is usually accompanied by a public oral defence event (a lecture or a colloquium) with one or more opponents. Habilitation is usually awarded 5–15 years after a PhD degree or its equivalent. Achieving this ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cancer
Cancer is a group of diseases involving Cell growth#Disorders, abnormal cell growth with the potential to Invasion (cancer), invade or Metastasis, spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible Signs and symptoms of cancer, signs and symptoms include a lump, abnormal bleeding, prolonged cough, unexplained weight loss, and a change in defecation, bowel movements. While these symptoms may indicate cancer, they can also have other causes. List of cancer types, Over 100 types of cancers affect humans. Tobacco use is the cause of about 22% of cancer deaths. Another 10% are due to obesity, poor Diet (nutrition), diet, sedentary lifestyle, lack of physical activity or Alcohol abuse, excessive alcohol consumption. Other factors include certain infections, exposure to ionizing radiation, and environmental pollutants. infectious causes of cancer, Infection with specific viruses, bacteria and parasites is an environmental factor cau ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunotherapy
Immunotherapy or biological therapy is the treatment of disease by activating or suppressing the immune system. Immunotherapies designed to elicit or amplify an immune response are classified as ''activation immunotherapies,'' while immunotherapies that reduce or suppress are classified as '' suppression immunotherapies''. Immunotherapy is under preliminary research for its potential to treat various forms of cancer. Cell-based immunotherapies are effective for some cancers. Immune effector cells such as lymphocytes, macrophages, dendritic cells, natural killer cells, and cytotoxic T lymphocytes work together to defend the body against cancer by targeting abnormal antigens expressed on the surface of tumor cells. Vaccine-induced immunity to COVID-19 relies mostly on an immunomodulatory T-cell response. Therapies such as granulocyte colony-stimulating factor (G-CSF), interferons, imiquimod and cellular membrane fractions from bacteria are licensed for medical use. Others in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tumor Antigen
Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers in identifying tumor cells with diagnostic tests and are potential candidates for use in cancer therapy. The field of cancer immunology studies such topics. Mechanism of tumor antigenesis Normal proteins in the body are not antigenic because of self-tolerance, a process in which self-reacting cytotoxic T lymphocytes (CTLs) and autoantibody-producing B lymphocytes are culled "centrally" in primary lymphatic tissue (BM) and "peripherally" in secondary lymphatic tissue (mostly thymus for T-cells and spleen/lymph nodes for B cells). Thus any protein that is not exposed to the immune system triggers an immune response. This may include normal proteins that are well sequestered from the immune system, proteins that are normally produced in extremely small quantities, proteins that are normally produced only in certain stages o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Research Foundation
The German Research Foundation ( ; DFG ) is a German research funding organization, which functions as a self-governing institution for the promotion of science and research in the Federal Republic of Germany. In 2019, the DFG had a funding budget of €3.3 billion. Function The DFG supports research in science, engineering, and the humanities through a variety of grant programmes, research prizes, and by funding infrastructure. The self-governed organization is based in Bonn and financed by the German states and the federal government of Germany. the organization consists of approximately 100 research universities and other research institutions. The DFG endows various research prizes, including the Leibniz Prize. The Polish-German science award Copernicus Award, Copernicus is offered jointly with the Foundation for Polish Science. According to a 2017 article in ''The Guardian'', the DFG has announced it will publish its research in online open-access journals. Background ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saarland
Saarland (, ; ) is a state of Germany in the southwest of the country. With an area of and population of 990,509 in 2018, it is the smallest German state in area apart from the city-states of Berlin, Bremen, and Hamburg, and the smallest in population apart from Bremen. Saarbrücken is the state capital and largest city; other cities include Neunkirchen and Saarlouis. Saarland is mainly surrounded by the department of Moselle (Grand Est) in France to the west and south and the neighboring state of Rhineland-Palatinate in Germany to the north and east; it also shares a small border about long with the canton of Remich in Luxembourg to the northwest. Having long been a relatively small part of the long-contested territories along the Franco-German linguistic border, Saarland first gained specific economic and strategic importance in the nineteenth century due to the wealth of its coal deposits and the heavy industrialization that grew as a result. Saarland was first est ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Doctorate
A doctorate (from Latin ''doctor'', meaning "teacher") or doctoral degree is a postgraduate academic degree awarded by universities and some other educational institutions, derived from the ancient formalism '' licentia docendi'' ("licence to teach"). In most countries, a research degree qualifies the holder to teach at university level in the degree's field or work in a specific profession. There are a number of doctoral degrees; the most common is the Doctor of Philosophy (PhD), awarded in many different fields, ranging from the humanities to scientific disciplines. Many universities also award honorary doctorates to individuals deemed worthy of special recognition, either for scholarly work or other contributions to the university or society. History Middle Ages The term ''doctor'' derives from Latin, meaning "teacher" or "instructor". The doctorate (Latin: ''doctoratus'') appeared in medieval Europe as a license to teach Latin (''licentia docendi'') at a university. Its ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homburg, Saarland
Homburg (; , ; ) is a town in Saarland, Germany and the administrative seat of the Saarpfalz district. With a population of 43,029 inhabitants (2022), it is the third largest town in the state. The city offers over 30,000 workplaces. The medical department of the University of Saarland is situated here. The city is also home to the Karlsberg beer brewery. Major employers include Robert Bosch GmbH, Schaeffler Group and Michelin. Geography Homburg is located in the northern part of the Saarpfalz district, bordering Rhineland-Palatinate. It is 16 km from Neunkirchen and 36 km from Saarbrücken. The city districts are situated in the Blies valley or on its tributaries Erbach, Lambsbach and Schwarzbach. Homburg is composed of Homburg center and nine city districts: Beeden, Bruchhof-Sanddorf, Einöd, Erbach, Jägersburg, Kirrberg, Reiskirchen, Schwarzenbach and Wörschweiler. Einöd includes: Einöd, Ingweiler and Schwarzenacker; Jägersburg includes Jäg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bad Harzburg
Bad Harzburg (; Eastphalian dialect, Eastphalian: ''Bad Harzborch'') is a spa town in central Germany, in the Goslar (district), Goslar district of Lower Saxony. It lies on the northern edge of the Harz mountains and is a recognised saltwater spa and climatic health resort. Geography Bad Harzburg is situated at the northern foot of the Harz mountain range on the edge of the Harz National Park. To the east of the borough is the boundary between the States of Germany, states of Lower Saxony and Saxony-Anhalt, the former Inner German Border. The small ''Radau'' river, a tributary to the Oker, has its source in the Harz mountains and flows through the town. Nearby are the towns of Goslar to the west, Vienenburg to the north, Braunlage to the south and Ilsenburg and Osterwieck in the east. Bad Harzburg is rich in natural resources such as gabbro, chalk, gravel, and oolithic iron ore (former Hansa Pit), all of which are or were mined in today's city's area. Climatically Bad Harzbur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Werner-von-Siemens-Gymnasium
The state school Werner-von-Siemens-Gymnasium in the district of Goslar is one of three high schools in Bad Harzburg. Pupils do not only come from Bad Harzburg, but also from the city of Vienenburg and Goslar (and the surrounding area). Pupils from Year 5 / age 10 (after elementary school) visit the school. It is named after the inventor Werner von Siemens. Location The Werner-von-Siemens-Gymnasium is located in the heart of the spa town of Bad Harzburg, which is on the northern edge of the Harz Mountains. From the school grounds, it is only a short walk to downtown Bad Harzburg with some shopping opportunities. The school is bordered by three streets, each with a separate entrance to the school grounds. Adjacent to the grounds is the town hall, offering plenty of parking. History After its foundation as a private school in 1869, the school developed to grammar school under the school conductor Friedrich Koldewey. When this development was completed eleven years later, the respo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
