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Zebrafish
The zebrafish (''Danio rerio'') is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes. Native to South Asia, it is a popular aquarium fish, frequently sold under the trade name zebra danio (and thus often called a " tropical fish" although both tropical and subtropical). It is also found in private ponds. The zebrafish is an important and widely used vertebrate model organism in scientific research, for example in drug development, in particular pre-clinical development. It is also notable for its regenerative abilities, and has been modified by researchers to produce many transgenic strains. Taxonomy The zebrafish is a derived member of the genus ''Brachydanio'', of the family Cyprinidae. It has a sister-group relationship with ''Danio aesculapii''. Zebrafish are also closely related to the genus ''Devario'', as demonstrated by a phylogenetic tree of close species. Distribution Range The zebrafish is native to fresh water habi ...
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Genetically Modified Organism
A genetically modified organism (GMO) is any organism whose genetic material has been altered using genetic engineering techniques. The exact definition of a genetically modified organism and what constitutes genetic engineering varies, with the most common being an organism altered in a way that "does not occur naturally by mating and/or natural recombination". A wide variety of organisms have been genetically modified (GM), from animals to plants and microorganisms. Genes have been transferred within the same species, across species (creating transgenic organisms), and even across kingdoms. New genes can be introduced, or endogenous genes can be enhanced, altered, or knocked out. Creating a genetically modified organism is a multi-step process. Genetic engineers must isolate the gene they wish to insert into the host organism and combine it with other genetic elements, including a promoter and terminator region and often a selectable marker. A number of techniques ar ...
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Model Organism
A model organism (often shortened to model) is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical. This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. Studying model organisms can be informative, but care must be taken when generalizing from one organism to another. In researching human disease, model organisms allow for better understanding the disease process without the added risk of harming an actual human. The species chosen will usually meet a determined taxonomic equivalency to humans, so as to react to disease or its treatment in a way that resemb ...
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Cypriniformes
Cypriniformes is an order of ray-finned fish, including the carps, minnows, loaches, and relatives. Cypriniformes is an Order within the Superorder Ostariophysi consisting of " Carp-like" Ostariophysins. This order contains 11-12 families, although some authorities have designated as many as 23, over 400 genera, and more than 4,250 species, with new species being described every few months or so, and new genera being recognized frequently.Eschmeyer, W.N., Fong, J.D. (2015Species by family/subfamilyin the Catalog of Fishes, California Academy of Sciences (retrieved 2 July 2015) They are most diverse in southeastern Asia, and are entirely absent from Australia and South America.Nelson (2006) At 112 years old, the longest-lived cypriniform fish documented is the bigmouth buffalo. Their closest living relatives are the Characiformes (characins and allies), the Gymnotiformes (electric eel and American knifefishes), and the Siluriformes (catfishes). Description Like ...
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Regeneration (biology)
In biology, regeneration is the process of renewal, restoration, and tissue growth that makes genomes, cells, organisms, and ecosystems resilient to natural fluctuations or events that cause disturbance or damage. Every species is capable of regeneration, from bacteria to humans. Regeneration can either be complete where the new tissue is the same as the lost tissue, or incomplete where after the necrotic tissue comes fibrosis. At its most elementary level, regeneration is mediated by the molecular processes of gene regulation and involves the cellular processes of cell proliferation, morphogenesis and cell differentiation. Regeneration in biology, however, mainly refers to the morphogenic processes that characterize the phenotypic plasticity of traits allowing multi-cellular organisms to repair and maintain the integrity of their physiological and morphological states. Above the genetic level, regeneration is fundamentally regulated by asexual cellular processes. Regenera ...
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Cyprinidae
Cyprinidae is a family of freshwater fish commonly called the carp or minnow family. It includes the carps, the true minnows, and relatives like the barbs and barbels. Cyprinidae is the largest and most diverse fish family and the largest vertebrate animal family in general with about 3,000 species, of which only 1,270 remain extant, divided into about 370 genera. Cyprinids range from about 12 mm in size to the giant barb (''Catlocarpio siamensis''). By genus and species count, the family makes up more than two-thirds of the ostariophysian order Cypriniformes. The family name is derived from the Greek word ( 'carp'). Biology and ecology Cyprinids are stomachless fish with toothless jaws. Even so, food can be effectively chewed by the gill rakers of the specialized last gill bow. These pharyngeal teeth allow the fish to make chewing motions against a chewing plate formed by a bony process of the skull. The pharyngeal teeth are unique to each species and are used b ...
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Devario
''Devario'' is a genus of fish in the family Cyprinidae native to the rivers and streams of South and Southeast Asia. These fishes have short barbels and many species having vertical or horizontal stripes. These species consume various small, aquatic insects, crustaceans and worms, as well as, in the case of fry, plankton. Species Currently, 43 species in this genus are recognized: * '' Devario acrostomus'' ( F. Fang & Kottelat, 1999) * ''Devario acuticephala'' ( Hora, 1921) * '' Devario aequipinnatus'' (McClelland, 1839) (Giant danio) * '' Devario affinis'' ( Blyth, 1860) * ''Devario annandalei'' (Chaudhuri, 1908) * ''Devario anomalus'' Conway, Mayden & Tang, 2009 * ''Devario apogon'' ( Chu, 1981) * '' Devario apopyris'' ( F. Fang & Kottelat, 1999) * '' Devario assamensis'' (Barman, 1984) * '' Devario auropurpureus'' ( Annandale, 1918) * '' Devario browni'' (Regan, 1907) * '' Devario chrysotaeniatus'' ( Chu, 1981) * '' Devario deruptotalea'' Ramananda & Vishwanath, ...
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Brachydanio
The danionins are a group of small, minnow-type fish belonging to the family Cyprinidae. Members of this group are mostly in the genera ''Danio'', ''Devario'', and ''Rasbora''._They_are_primarily_native_to_the_ s_...''._They_are_primarily_native_to_the_fresh_water">outheast_Asia,_as_well_as_southeast_China._A_single_species,_''R._gerlachi'',_is_only_known_from_an_old_Zoological_specimen">s_...''._They_are_primarily_native_to_the_fresh_waters_of_South_Asia.html" ;"title="fresh_water.html" ;"title="outheast Asia, as well as southeast China. A single species, ''R. gerlachi'', is only known from an old Zoological specimen">s ...''. They are primarily native to the fresh water">outheast Asia, as well as southeast China. A single species, ''R. gerlachi'', is only known from an old Zoological specimen">s ...''. They are primarily native to the fresh waters of South Asia">South and Southeast Asia, with fewer species in Africa. Many species are brightly coloured and are available as aquari ...
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Cladistics
Cladistics (; ) is an approach to biological classification in which organisms are categorized in groups (" clades") based on hypotheses of most recent common ancestry. The evidence for hypothesized relationships is typically shared derived characteristics ( synapomorphies'')'' that are not present in more distant groups and ancestors. However, from an empirical perspective, common ancestors are inferences based on a cladistic hypothesis of relationships of taxa whose character states can be observed. Theoretically, a last common ancestor and all its descendants constitute a (minimal) clade. Importantly, all descendants stay in their overarching ancestral clade. For example, if the terms ''worms'' or ''fishes'' were used within a ''strict'' cladistic framework, these terms would include humans. Many of these terms are normally used paraphyletically, outside of cladistics, e.g. as a ' grade', which are fruitless to precisely delineate, especially when including extinct species. ...
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Danio Aesculapii
The panther danio (''Danio aesculapii'') is a species of danio endemic to Myanmar. Before its description it was referred to as Danio species TW03. The panther is a smallish danio which on first glance looks a little dull, but displays a variety of colours when sunlight illuminates the fish on its side. References *http://www.seriouslyfish.com {{Taxonbar, from=Q5435401 Danio Endemic fauna of Myanmar Taxa named by Sven O. Kullander Taxa named by Fang Fang Kullander Fish described in 2009 ...
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Pakistan
Pakistan ( ur, ), officially the Islamic Republic of Pakistan ( ur, , label=none), is a country in South Asia. It is the world's List of countries and dependencies by population, fifth-most populous country, with a population of almost 243 million people, and has the world's Islam by country#Countries, second-largest Muslim population just behind Indonesia. Pakistan is the List of countries and dependencies by area, 33rd-largest country in the world by area and 2nd largest in South Asia, spanning . It has a coastline along the Arabian Sea and Gulf of Oman in the south, and is bordered by India to India–Pakistan border, the east, Afghanistan to Durand Line, the west, Iran to Iran–Pakistan border, the southwest, and China to China–Pakistan border, the northeast. It is separated narrowly from Tajikistan by Afghanistan's Wakhan Corridor in the north, and also shares a maritime border with Oman. Islamabad is the nation's capital, while Karachi is its largest city and fina ...
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Phylogenetic Tree
A phylogenetic tree (also phylogeny or evolutionary tree Felsenstein J. (2004). ''Inferring Phylogenies'' Sinauer Associates: Sunderland, MA.) is a branching diagram or a tree showing the evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical or genetic characteristics. All life on Earth is part of a single phylogenetic tree, indicating common ancestry. In a ''rooted'' phylogenetic tree, each node with descendants represents the inferred most recent common ancestor of those descendants, and the edge lengths in some trees may be interpreted as time estimates. Each node is called a taxonomic unit. Internal nodes are generally called hypothetical taxonomic units, as they cannot be directly observed. Trees are useful in fields of biology such as bioinformatics, systematics, and phylogenetics. ''Unrooted'' trees illustrate only the relatedness of the leaf nodes and do not require the ancestral root to ...
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India
India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the List of countries and dependencies by area, seventh-largest country by area, the List of countries and dependencies by population, second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the south, the Arabian Sea on the southwest, and the Bay of Bengal on the southeast, it shares land borders with Pakistan to the west; China, Nepal, and Bhutan to the north; and Bangladesh and Myanmar to the east. In the Indian Ocean, India is in the vicinity of Sri Lanka and the Maldives; its Andaman and Nicobar Islands share a maritime border with Thailand, Myanmar, and Indonesia. Modern humans arrived on the Indian subcontinent from Africa no later than 55,000 years ago., "Y-Chromosome and Mt-DNA data support the colonization of South Asia by modern humans originating in Africa. ... Coalescence dates for most non-European populations average to betwee ...
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