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OpenPHACTS
Open PHACTS (Open Pharmacological Concept Triple Store) was a European initiative public–private partnership between academia, publishers, enterprises, pharmaceutical companies and other organisations working to enable better, cheaper and faster drug discovery. It has been funded by the Innovative Medicines Initiative, selected as part of three projects to "design methods for common standards and sharing of data for more efficient drug development and patient treatment in the future". Partnerships A total of 27 partners were involved including: * Academia: Maastricht University, University of Santiago de Compostela, University of Vienna, University of Manchester, University of Bonn, Swiss Institute of Bioinformatics, European Bioinformatics Institute, Vrije Universiteit of Amsterdam, Technical University of Denmark, University of Hamburg * Pharmaceutical companies: Pfizer, Merck KGaA, Eli Lilly and Company, Novartis, GlaxoSmithKline, AstraZeneca * Other companies: ChemSpider, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barend Mons
Barend Mons (born 1957, The Hague) is a molecular biologist by training and a leading FAIR data specialist. The first decade of his scientific career he spent on fundamental research on malaria parasites and later on translational research for malaria vaccines. In the year 2000 he switched to advanced data stewardship and (biological) systems analytics. He is currently a professor in Leiden and most known for innovations in scholarly collaboration, especially nanopublications, knowledge graph based discovery and most recently the FAIR data initiative and GO FAIR. Since 2012 he is a Professor in biosemantics in the Department of Human Genetics at the Leiden University Medical Center (LUMC) in The Netherlands. In 2015 Barend was appointed chair of the High Level Expert Group on the European Open Science Cloud. Since 2017 Barend is heading the International Support and Coordination office of the GO FAIR initiative. He is also the elected president of CODATA, the standing committ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ChemSpider
ChemSpider is a database of chemicals. ChemSpider is owned by the Royal Society of Chemistry. Database The database contains information on more than 100 million molecules from over 270 data sources including: * EPA DSSTox * U.S. Food and Drug Administration (FDA) * Human Metabolome Database * Journal of Heterocyclic Chemistry * KEGG * KUMGM * LeadScope * LipidMAPS * Marinlit * MDPI * MICAD * MLSMR * MMDB * MOLI * MTDP * Nanogen * Nature Chemical Biology * NCGC * NIAID * National Institutes of Health (NIH) * NINDS Approved Drug Screening Program * NIST * NIST Chemistry WebBook * NMMLSC * NMRShiftDB * PANACHE * PCMD * PDSP * Peptides * Prous Science Drugs of the Future * QSAR * R&D Chemicals * San Diego Center for Chemical Genomics * SGCOxCompounds, SGCStoCompounds * SMID * Specs * Structural Genomics Consortium * SureChem * Synthon-Lab * Thomson Pharma * Total TOSLab Building-Blocks * UM-BBD * UPCMLD * UsefulChem * Web of Science * xPharm Each chemical is given a unique i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antony John Williams
Antony John Williams is a British chemist and expert in the fields of both nuclear magnetic resonance (NMR) spectroscopy and cheminformatics at the United States Environmental Protection Agency. He is the founder of the ChemSpider website that was purchased by the Royal Society of Chemistry in May 2009. He is a science blogger and an author. Early life and education Antony Williams was born in St Asaph, Wales, June 1964 to Ernest Edward Williams, owner of a building contracting firm, and Eirlys Elizabeth Williams. He has one older sister, Rae. He grew up in a small village near Caerwys. Williams attended Primary School in both Holywell and Nannerch until 1975. From the age of eleven, he attended Alun School where he received A-levels in mathematics, geography, and chemistry. Williams earned his Bachelor of Science in chemistry from the University of Liverpool, in 1985, writing an undergraduate dissertation on "Spectroscopic Studies of Vitamin E Related Systems" where he app ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carole Goble
Carole Anne Goble, (born 10 April 1961) is a British academic who is Professor of Computer Science at the University of Manchester. She is principal investigator (PI) of the myGrid, BioCatalogue and myExperiment projects and co-leads the Information Management Group (IMG) with Norman Paton. Education Goble was educated at Maidstone School for Girls. Her academic career has been spent at the Department of Computer Science where she gained her Bachelor of Science degree in computing and information systems from 1979 to 1982. Research and career Her current research interests include Grid computing, the Semantic Grid, the Semantic Web, Ontologies, e-Science, medical informatics, Bioinformatics, and Research Objects. She applies advances in knowledge technologies and workflow systems to solve information management problems for life scientists and other scientific disciplines. She has successfully secured funding from the European Union, the Defense Advanced Research Projects ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gerhard Ecker
Gerhard F. Ecker is an Austrian medicinal chemist and expert in the fields of Pharmacoinformatics at the University of Vienna, where he is the Professor for Pharmacoinformatics and Head of thPharmacoinformatics Research Groupat the Department of Medicinal Chemistry. He also coordinates the research focus "Computational Life Sciences" of the Faculty of Life Sciences. Career Ecker received his doctorate in natural sciences from the University of Vienna in 1991, became appointed Associate Professor for Medicinal Chemistry in 1998 and Full Professor for Pharmacoinformatics in 2009. Ecker is Editor of Molecular Informatics and coordinates the EUROPIN PhD programme in Pharmacoinformatics. Currently he is also President of the European Federation for Medicinal Chemistry. Research Ecker's research focuses on computational drug design which not only led to the identification of highly active propafenone-type inhibitors of P-glycoprotein, but also paved the way for development of new desc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pfizer
Pfizer Inc. ( ) is an American multinational pharmaceutical and biotechnology corporation headquartered on 42nd Street in Manhattan, New York City. The company was established in 1849 in New York by two German entrepreneurs, Charles Pfizer (1824–1906) and his cousin Charles F. Erhart (1821–1891). Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company has several blockbuster drugs or products that each generate more than billion in annual revenues. In 2020, 52% of the company's revenues came from the United States, 6% came from each of China and Japan, and 36% came from other countries. Pfizer was a component of the Dow Jones Industrial Average stock market index from 2004 to August 2020. The company ranks 64th on the Fortune 500 and 49th on the Forbes Global 2000. History 1849–1950: Early history Pfizer was founded in 1849 by Charles Pfizer and Charles F. Erhart, two cousins who had i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Bioinformatics Institute
The European Bioinformatics Institute (EMBL-EBI) is an Intergovernmental Organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Wellcome Genome Campus in Hinxton near Cambridge, and employs over 600 full-time equivalent (FTE) staff. Institute leaders such as Rolf Apweiler, Alex Bateman, Ewan Birney, and Guy Cochrane, an adviser on the National Genomics Data Center Scientific Advisory Board, serve as part of the international research network of the BIG Data Center at the Beijing Institute of Genomics. Additionally, the EMBL-EBI hosts training programs that teach scientists the fundamentals of the work with biological data and promote the plethora of bioinformatic tools available for their research, both EMBL-EBI and non-EMBL-EBI-based. Bioinformatic services One of the roles of the EMBL-EBI is to index and maintain biological data in a set of databases, including E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vrije Universiteit
The Vrije Universiteit Amsterdam (abbreviated as ''VU Amsterdam'' or simply ''VU'' when in context) is a public research university in Amsterdam, Netherlands, being founded in 1880. The VU Amsterdam is one of two large, publicly funded research universities in the city, the other being the University of Amsterdam (UvA). The literal translation of the Dutch name ''Vrije Universiteit'' is "Free University". "Free" refers to independence of the university from both the State and the Dutch Reformed Church. Both within and outside the university, the institution is commonly referred to as "the VU". Although founded as a private institution, the VU has received government funding on a parity basis with public universities since 1970. The university is located on a compact urban campus in the southern Buitenveldert neighbourhood of Amsterdam and adjacent to the modern Zuidas business district. The University consistently ranks among the top 150 universities in the world by prominent int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Technical University Of Denmark
The Technical University of Denmark ( da, Danmarks Tekniske Universitet), often simply referred to as DTU, is a polytechnic university and school of engineering. It was founded in 1829 at the initiative of Hans Christian Ørsted as Denmark's first polytechnic, and it is today ranked among Europe's leading engineering institutions. It is located in the town Kongens Lyngby, north of central Copenhagen, Denmark. Along with École Polytechnique in Paris, École Polytechnique Fédérale de Lausanne, Eindhoven University of Technology, Technical University of Munich and Technion – Israel Institute of Technology, DTU is a member of EuroTech Universities Alliance. History DTU was founded in 1829 as the "College of Advanced Technology" (Danish: Den Polytekniske Læreanstalt). The Physicist Hans Christian Ørsted, at that time a professor at the University of Copenhagen, was one of the driving forces behind this initiative. He was inspired by the École Polytechnique in Paris, Fran ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Hamburg
The University of Hamburg (german: link=no, Universität Hamburg, also referred to as UHH) is a public research university in Hamburg, Germany. It was founded on 28 March 1919 by combining the previous General Lecture System ('' Allgemeines Vorlesungswesen''), the Hamburg Colonial Institute ('' Hamburgisches Kolonialinstitut''), and the Academic College ('' Akademisches Gymnasium''). The main campus is located in the central district of Rotherbaum, with affiliated institutes and research centres distributed around the city-state. The university has been ranked in the top 200 universities worldwide by the ''Times Higher Education Ranking'', the Shanghai Ranking and the CWTS Leiden Ranking, placing it among the top 1% of global universities. Seven Nobel Prize winners and one Wolf Prize winner are affiliated with UHH. On a national scale, '' U.S. News & World Report'' ranks UHH 7th and ''QS World University Rankings'' 14th out of a total of 426 German institutions of higher educa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novartis
Novartis AG is a Swiss-American multinational pharmaceutical corporation based in Basel, Switzerland and Cambridge, Massachusetts, United States (global research).name="novartis.com">https://www.novartis.com/research-development/research-locations It is one of the largest pharmaceutical companies in the world. Novartis manufactures the drugs clozapine (Clozaril), diclofenac (Voltaren; sold to GlaxoSmithKline in 2015 deal), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec/Glivec), cyclosporine (Neoral/Sandimmune), letrozole (Femara), methylphenidate (Ritalin; production ceased 2020), terbinafine (Lamisil), deferasirox (Exjade), and others. In March 1996, the companies Ciba-Geigy and Sandoz merged to form Novartis; the pharmaceutical and agrochemical divisions of both companies formed Novartis as an independent entity. Other Ciba-Geigy and Sandoz businesses were sold, or, like Ciba Specialty Chemicals, spun off as independent companies. The Sandoz brand ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck KGaA
The Merck Group, branded and commonly known as Merck, is a German multinational science and technology company headquartered in Darmstadt, with about 60,000 employees and present in 66 countries. The group includes around 250 companies; the main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies in the world. Merck operates in Europe, Africa, Asia, Oceania and the Americas. It has major research and development centres in Darmstadt, Boston, Tokyo and Beijing, as well as other Research and Development units in Taiwan, France, Israel, South Korea, India and in the UK. Merck pioneered the commercial manufacture of morphine in the 19th century and for a time held a virtual monopoly on cocaine. Merck was privately owned until going public on the Frankfurt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
