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Antony John Williams
Antony John Williams is a British chemist and expert in the fields of both nuclear magnetic resonance (NMR) spectroscopy and cheminformatics at the United States Environmental Protection Agency. He is the founder of the ChemSpider website that was purchased by the Royal Society of Chemistry in May 2009. He is a science blogger and an author. Early life and education Antony Williams was born in St Asaph, Wales, June 1964 to Ernest Edward Williams, owner of a building contracting firm, and Eirlys Elizabeth Williams. He has one older sister, Rae. He grew up in a small village near Caerwys. Williams attended Primary School in both Holywell and Nannerch until 1975. From the age of eleven, he attended Alun School where he received A-levels in mathematics, geography, and chemistry. Williams earned his Bachelor of Science in chemistry from the University of Liverpool, in 1985, writing an undergraduate dissertation on "Spectroscopic Studies of Vitamin E Related Systems" where he app ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
St Asaph
St Asaph (; cy, Llanelwy "church on the Elwy") is a City status in the United Kingdom, city and community (Wales), community on the River Elwy in Denbighshire, Wales. In the United Kingdom Census 2011, 2011 Census it had a population of 3,355, making it the List of smallest cities in the United Kingdom, second-smallest city in Britain in terms of population and Urban area#United Kingdom, urban area. It is in the Historic counties of Wales, historic county of Flintshire (historic), Flintshire. The city of St Asaph is surrounded by countryside and views of the Vale of Clwyd. It is situated close to a number of busy coastal towns such as Rhyl, Prestatyn, Abergele, Colwyn Bay and Llandudno. The historic castles of Denbigh and Rhuddlan are also nearby History The earliest inhabitants of the vale of Elwy lived at the nearby Paleolithic site of Pontnewydd Cave, Pontnewydd (Bontnewydd), which was excavated from 1978 by a team from the University of Wales, led by Stephen Aldhouse Gree ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuclear Magnetic Resonance
Nuclear magnetic resonance (NMR) is a physical phenomenon in which nuclei in a strong constant magnetic field are perturbed by a weak oscillating magnetic field (in the near field) and respond by producing an electromagnetic signal with a frequency characteristic of the magnetic field at the nucleus. This process occurs near resonance, when the oscillation frequency matches the intrinsic frequency of the nuclei, which depends on the strength of the static magnetic field, the chemical environment, and the magnetic properties of the isotope involved; in practical applications with static magnetic fields up to ca. 20 tesla, the frequency is similar to VHF and UHF television broadcasts (60–1000 MHz). NMR results from specific magnetic properties of certain atomic nuclei. Nuclear magnetic resonance spectroscopy is widely used to determine the structure of organic molecules in solution and study molecular physics and crystals as well as non-crystalline materials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alun School
Alun School is a secondary school located in the community of Mold, Flintshire, Wales. It was formed in 1970 as a result of the merger of the Alun Grammar School and the Daniel Owen Secondary Modern School. Some of the school's present buildings, such as the Daniel Owen Building, date from 1938. The remainder were opened on the formation of the current comprehensive or built in the years since. In 1989, 1432 students attended the school; by 2009 the number was 1762, with over 550 students in the sixth form and over 120 teachers. The main school remains over-subscribed and the Sixth Form is one of the biggest in Wales. The school is sometimes known colloquially as ''Mold Alun'', to distinguish it from the nearby Castell Alun secondary school in Hope. Buildings The Alun has many distinguishable buildings and areas. These include: * Lloyd Parry Building containing Biology rooms, Library and the Reception. * Tower Block containing the G Floor (sixth form), L Floor (computers), M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nannerch
Nannerch is a village and community in Flintshire, Wales, located within the Clwydian Range and Dee Valley Area of Outstanding Natural Beauty. At the 2001 Census the population of Nannerch was 531, reducing to 496 in 2011. History Nannerch (pronounced Nan-er-ch Welsh) is one of the ancient parishes of Flintshire, made up of the townships of Trellan, Trefechan, Trecwm and Tre Penbedw. It is an ancient village, sitting on bedrock of Carboniferous Limestone, overlain by glacial boulder clay with glacial hollows. The limestone has been used in the construction of many local buildings. The ruins of Iron Age hill forts at Pen-y-Cloddiau and Moel Arthur are situated in the nearby hills. The Church The church, which is dedicated to St. Michael and All Angels, was consecrated on 29 September 1853. It is the third church known to have been built on the site. The curved wall of the graveyard indicates the ancient origins of the churches. The present church was designed by Thomas W. Wya ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Holywell, Flintshire
Holywell ( '','' cy, Treffynnon) is a market town and community in Flintshire, Wales. It lies to the west of the estuary of the River Dee. The community includes Greenfield. Etymology The name Holywell is literally ' + ' in reference to St Winefride's Well, which is situated in the town. Similarly, its Welsh name, ', is a compound of ' "town" + ' "well", meaning "town of hewell". History The market town of Holywell is known for St Winefride's Well, a holy well surrounded by a chapel, itself known since at least the Roman period. It has been a site of Christian pilgrimage since about 660, dedicated to Saint Winefride who, according to legend, was beheaded there by Caradog who attempted to attack her. The well is one of the Seven Wonders of Wales and the town bills itself as ''The Lourdes of Wales''. Many pilgrims from all over the world continue to visit Holywell and the well. From the 18th century, the town grew around the lead mining and cotton milling industries. The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caerwys
Caerwys is a town in Flintshire, Wales. It is just under two miles from the A55 road, A55 North Wales Expressway and one mile from the A541 road, A541 Mold, Flintshire, Mold-Denbigh road. At the United Kingdom Census 2001, 2001 Census, the population of Caerwys Community (Wales), community was 1,315, with a total Ward (country subdivision), ward population of 2,496. Following reorganisation the community population fell at the 2011 Census to 1,283 with the ward raising to 2,569. The community includes Afonwen. History Caerwys is mentioned in the ''Domesday Book'' as a small market town. The well-maintained Church (building), church is dedicated to St. Michael. It has two parallel naves. The oldest part of the building is a stone tower whose base is said to have been part of a Roman Empire, Roman observation tower . Within the church is the cover slab of a tomb reputed to have been that of Elizabeth Ferrers, the wife of Dafydd ap Gruffudd, prince of Wales (d. 1283). A short, info ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wales
Wales ( cy, Cymru ) is a Countries of the United Kingdom, country that is part of the United Kingdom. It is bordered by England to the Wales–England border, east, the Irish Sea to the north and west, the Celtic Sea to the south west and the Bristol Channel to the south. It had a population in 2021 of 3,107,500 and has a total area of . Wales has over of coastline and is largely mountainous with its higher peaks in the north and central areas, including Snowdon (), its highest summit. The country lies within the Temperateness, north temperate zone and has a changeable, maritime climate. The capital and largest city is Cardiff. Welsh national identity emerged among the Celtic Britons after the Roman withdrawal from Britain in the 5th century, and Wales was formed as a Kingdom of Wales, kingdom under Gruffydd ap Llywelyn in 1055. Wales is regarded as one of the Celtic nations. The Conquest of Wales by Edward I, conquest of Wales by Edward I of England was completed by 1283, th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cheminformatics
Cheminformatics (also known as chemoinformatics) refers to use of physical chemistry theory with computer and information science techniques—so called "''in silico''" techniques—in application to a range of descriptive and prescriptive problems in the field of chemistry, including in its applications to biology and related molecular fields. Such ''in silico'' techniques are used, for example, by pharmaceutical companies and in academic settings to aid and inform the process of drug discovery, for instance in the design of well-defined combinatorial libraries of synthetic compounds, or to assist in structure-based drug design. The methods can also be used in chemical and allied industries, and such fields as environmental science and pharmacology, where chemical processes are involved or studied. History Cheminformatics has been an active field in various guises since the 1970s and earlier, with activity in academic departments and commercial pharmaceutical research and dev ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nuclear Magnetic Resonance Spectroscopy
Nuclear magnetic resonance spectroscopy, most commonly known as NMR spectroscopy or magnetic resonance spectroscopy (MRS), is a spectroscopic technique to observe local magnetic fields around atomic nuclei. The sample is placed in a magnetic field and the NMR signal is produced by excitation of the nuclei sample with radio waves into nuclear magnetic resonance, which is detected with sensitive radio receivers. The intramolecular magnetic field around an atom in a molecule changes the resonance frequency, thus giving access to details of the electronic structure of a molecule and its individual functional groups. As the fields are unique or highly characteristic to individual compounds, in modern organic chemistry practice, NMR spectroscopy is the definitive method to identify monomolecular organic compounds. The principle of NMR usually involves three sequential steps: # The alignment (polarization) of the magnetic nuclear spins in an applied, constant magnetic field B0. # The ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of subdisciplines of chemistry. Materials scientists and metallurgists share much of the same education and skills with chemists. The work of chemists is often related to the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
British People
British people or Britons, also known colloquially as Brits, are the citizens of the United Kingdom of Great Britain and Northern Ireland, the British Overseas Territories, and the Crown dependencies.: British nationality law governs modern British citizenship and nationality, which can be acquired, for instance, by descent from British nationals. When used in a historical context, "British" or "Britons" can refer to the Ancient Britons, the indigenous inhabitants of Great Britain and Brittany, whose surviving members are the modern Welsh people, Cornish people, and Bretons. It also refers to citizens of the former British Empire, who settled in the country prior to 1973, and hold neither UK citizenship nor nationality. Though early assertions of being British date from the Late Middle Ages, the Union of the Crowns in 1603 and the creation of the Kingdom of Great Britain in 1707 triggered a sense of British national identity.. The notion of Britishness and a shared Brit ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Notebook Science
Open-notebook science is the practice of making the entire primary record of a research project publicly available online as it is recorded. This involves placing the personal, or laboratory, notebook of the researcher online along with all raw and processed data, and any associated material, as this material is generated. The approach may be summed up by the slogan 'no insider information'. It is the logical extreme of transparent approaches to research and explicitly includes the making available of failed, less significant, and otherwise unpublished experiments; so called 'dark data'.Freeing the Dark Data of Failed Scientific Experiments Goetz, T., Wired Magazine, Sept.25, 2007 The practice of open notebook science, although not the norm in the |
