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OpenPHACTS
Open PHACTS (Open Pharmacological Concept Triple Store) was a European initiative public–private partnership between academia, publishers, enterprises, pharmaceutical companies and other organisations working to enable better, cheaper and faster drug discovery. It has been funded by the Innovative Medicines Initiative, selected as part of three projects to "design methods for common standards and sharing of data for more efficient drug development and patient treatment in the future". Partnerships A total of 27 partners were involved including: * Academia: Maastricht University, University of Santiago de Compostela, University of Vienna, University of Manchester, University of Bonn, Swiss Institute of Bioinformatics, European Bioinformatics Institute, Vrije Universiteit of Amsterdam, Technical University of Denmark, University of Hamburg * Pharmaceutical companies: Pfizer, Merck KGaA, Eli Lilly and Company, Novartis, GlaxoSmithKline, AstraZeneca * Other companies: ChemSpider, Bi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Barend Mons
Barend Mons (born 1957, The Hague) is a molecular biologist and a FAIR data specialist. The first decade of his scientific career he spent on fundamental research on malaria parasites and later on translational research for malaria vaccines. In the year 2000 he switched to advanced data stewardship and (biological) systems analytics. He is most known for innovations in scholarly collaboration, especially nanopublications, and knowledge graph based discovery. In 2012 Barend was appointed full Professor in biosemantics in the Department of Human Genetics at the Leiden University Medical Center (LUMC) in The Netherlands. In 2014 he organised the seminal FAIR conference at the Lorentz centre that led to the FAIR data initiative and GO FAIR. In 2015 he was appointed chair of the High Level Expert Group on the European Open Science Cloud. From 2018 to 2023 Barend was the elected president of CODATA, the affiliated organisation on research data related issues of the Internation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ChemSpider
ChemSpider is a freely accessible online chemical database, database of chemicals owned by the Royal Society of Chemistry. It contains information on more than 100 million molecules from over 270 data sources, each of them receiving a unique identifier called ChemSpider Identifier. Sources The database sources include: Professional databases * EPA DSSTox * Food and Drug Administration (United States), U.S. Food and Drug Administration (FDA) * Human Metabolome Database * Journal of Heterocyclic Chemistry * KEGG * KUMGM * LeadScope * LIPID MAPS, LipidMAPS * Marinlit * MDPI * MICAD * MLSMR * MMDB * MOLI * MTDP * Nanogen * Nature Chemical Biology * NCGC * NIAID * National Institutes of Health (NIH) * NINDS Approved Drug Screening Program * NIST * NIST Chemistry WebBook * NMMLSC * NMRShiftDB * PANACHE * PCMD * PDSP * Peptides (journal), Peptides * Prous Science Drugs of the Future * QSAR * R&D Chemicals * San Diego Center for Chemical Genomics * SGCOxCompounds, SGCStoCompounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antony John Williams
Antony John Williams is a British chemist and expert in the fields of both nuclear magnetic resonance (NMR) spectroscopy and cheminformatics at the United States Environmental Protection Agency. He is the founder of the ChemSpider website that was purchased by the Royal Society of Chemistry in May 2009. He is a science blogger and an author. Early life and education Antony Williams was born in St Asaph, Wales, June 1964 to Ernest Edward Williams, owner of a building contracting firm, and Eirlys Elizabeth Williams. He has one older sister, Rae. He grew up in a small village near Caerwys. Williams attended Primary School in both Holywell and Nannerch until 1975. From the age of eleven, he attended Alun School where he received A-levels in mathematics, geography, and chemistry. Williams earned his Bachelor of Science in chemistry from the University of Liverpool, in 1985, writing an undergraduate dissertation on "Spectroscopic Studies of Vitamin E Related Systems" whe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carole Goble
Carole Anne Goble, (born 10 April 1961) is a British academic who is Professor of Computer Science at the University of Manchester. She is principal investigator (PI) of the myGrid, BioCatalogue and myExperiment projects and co-leads the Information Management Group (IMG) with Norman Paton. Education Goble was educated at Maidstone School for Girls, now called Invicta Grammar School. Her academic career has been spent at the Department of Computer Science, where she gained her Bachelor of Science degree in computing and information systems from 1979 to 1982. Research and career Goble's research interests include grid computing, the semantic grid, the Semantic Web, ontologies, e-Science, medical informatics, bioinformatics, and Research Objects. She applies advances in knowledge technologies and workflow systems to solve information management problems for life scientists and other scientific disciplines. She has successfully secured funding from the European Union, t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gerhard Ecker
Gerhard F. Ecker is an Austrian medicinal chemist and expert in the fields of Pharmacoinformatics at the University of Vienna, where he is the Professor for Pharmacoinformatics and Head of thPharmacoinformatics Research Groupat the Department of Medicinal Chemistry. He also coordinates the research focus "Computational Life Sciences" of the Faculty of Life Sciences. Career Ecker received his doctorate in natural sciences from the University of Vienna in 1991, became appointed Associate Professor for Medicinal Chemistry in 1998 and Full Professor for Pharmacoinformatics in 2009. Ecker is Editor of Molecular Informatics and coordinates the EUROPIN PhD programme in Pharmacoinformatics. Currently he is also President of the European Federation for Medicinal Chemistry. Research Ecker's research focuses on computational drug design which not only led to the identification of highly active propafenone-type inhibitors of P-glycoprotein, but also paved the way for development of new de ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pfizer
Pfizer Inc. ( ) is an American Multinational corporation, multinational Pharmaceutical industry, pharmaceutical and biotechnology corporation headquartered at The Spiral (New York City), The Spiral in Manhattan, New York City. Founded in 1849 in New York by German entrepreneurs Charles Pfizer (1824–1906) and Charles F. Erhart (1821–1891), Pfizer is one of the oldest pharmaceutical companies in North America. Pfizer develops and produces medicines and vaccines for immunology, oncology, cardiology, endocrinology, and neurology. The company's largest products by sales are the Pfizer–BioNTech COVID-19 vaccine ($11 billion in 2023 revenues), apixaban ($6 billion in 2023 revenues), a pneumococcal conjugate vaccine ($6 billion in 2023 revenues), palbociclib ($4 billion in 2023 revenues), and tafamidis ($3 billion in 2023 revenues). In 2023, 46% of the company's revenues came from the United States, 6% came from Japan, and 48% came from other countries. Pfizer has been a publi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Bioinformatics Institute
The European Bioinformatics Institute (EMBL-EBI) is an intergovernmental organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Wellcome Genome Campus in Hinxton near Cambridge, and employs over 600 full-time equivalent (FTE) staff. Further, the EMBL-EBI hosts training programs that teach scientists the fundamentals of the work with biological data and promote the plethora of bioinformatic tools available for their research, both EMBL-EBI-based and not so. Bioinformatic services One of the roles of the EMBL-EBI is to index and maintain biological data in a set of databases, including Ensembl (housing whole genome sequence data), UniProt (protein sequence and annotation database) and Protein Data Bank (protein and nucleic acid tertiary structure database). A variety of online services and tools is provided, such as Basic Local Alignment Search Tool (BLAST) or Clust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vrije Universiteit
The (abbreviated as ''VU Amsterdam'' or simply ''VU'' when in context) is a public research university in Amsterdam, Netherlands, founded in 1880. The VU Amsterdam is one of two large, publicly funded research universities in the city, the other being the University of Amsterdam (UvA). The literal translation of the Dutch name is "Free University". "Free" refers to independence of the university from both the State and the Dutch Reformed Church. Both within and outside the university, the institution is commonly referred to as "the VU". Although founded as a private institution, the VU has received government funding on a parity basis with public universities since 1970. The university is located on a compact urban campus in the southern Buitenveldert neighbourhood of Amsterdam and adjacent to the modern Zuidas business district. As of October 2021, the VU had 29,796 registered students, most of whom were full-time students. That year, the university had 2,263 faculty members ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Technical University Of Denmark
The Technical University of Denmark (), often simply referred to as DTU, is a polytechnic university and school of engineering. It was founded in 1829 at the initiative of Hans Christian Ørsted as Denmark's first polytechnic, and it is today ranked among Europe's leading engineering institutions. It is located in the town Kongens Lyngby, north of central Copenhagen, Denmark. Along with École Polytechnique in Paris, École Polytechnique Fédérale de Lausanne, Eindhoven University of Technology, Technical University of Munich and Technion – Israel Institute of Technology, DTU is a member of EuroTech Universities Alliance. History DTU was founded in 1829 as the "College of Advanced Technology" (Danish: Den Polytekniske Læreanstalt). The Physicist Hans Christian Ørsted, at that time a professor at the University of Copenhagen, was one of the driving forces behind this initiative. He was inspired by the École Polytechnique in Paris, France which Ørsted had visited as a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Hamburg
The University of Hamburg (, also referred to as UHH) is a public university, public research university in Hamburg, Germany. It was founded on 28 March 1919 by combining the previous General Lecture System ('':de:Allgemeines Vorlesungswesen, Allgemeines Vorlesungswesen''), the Hamburg Colonial Institute ('':de:Hamburgisches Kolonialinstitut, Hamburgisches Kolonialinstitut''), and the Academic College ('':de:Akademisches Gymnasium (Hamburg), Akademisches Gymnasium''). The main campus is located in the central district of Rotherbaum, with affiliated institutes and research centres distributed around the city-state. Seven Nobel Prize winners and one Wolf Prize winner are affiliated with UHH. History Founding At the beginning of the 20th century, wealthy individuals made several unsuccessful petitions to the Hamburg Senate and Parliament requesting the establishment of a university. Senator Werner von Melle worked towards the merging of existing institutions into one university, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Novartis
Novartis AG is a Swiss multinational corporation, multinational pharmaceutical company, pharmaceutical corporation based in Basel, Switzerland. Novartis is one of the largest pharmaceutical companies in the world and was the eighth largest by revenue in 2024. Novartis manufactures the drugs clozapine (Clozaril), diclofenac (Voltaren; sold to GlaxoSmithKline in 2015 deal), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec/Glivec), cyclosporine (Neoral/Sandimmune), letrozole (Femara), methylphenidate (Ritalin; produced by Sandoz since 2023), terbinafine (Lamisil), deferasirox (Exjade), and others. Novartis was formed in 1996 by the merger of Ciba-Geigy and Sandoz. It was considered the largest corporate merger in history during that time. The pharmaceutical and agrochemical divisions of both companies formed Novartis as an independent entity. The name Novartis was based on the Latin terms, ''novae artes'' (new skills). After the merger, other Ciba-Geigy and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Merck KGaA
The Merck Group, branded and commonly known as Merck, is a German Multinational corporation, multinational science and technology company headquartered in Darmstadt, with about 60,000 employees and a presence in 66 countries. The group includes around 250 companies; the main company is Merck KGaA in Germany. The company is divided into three business lines: Healthcare, Life Sciences and Electronics. Merck was founded in 1668 and is the world's oldest operating chemical and pharmaceutical company, as well as one of the largest pharmaceutical companies globally. Merck operates in Europe, Africa, Asia, Oceania and the Americas. It has major research and development centres in Darmstadt, Boston, Tokyo and Beijing, as well as other Research and Development units in Taiwan, France, Israel, South Korea, India, and the UK. Merck pioneered the commercial manufacture of morphine in the 19th century and for a time held a virtual monopoly on cocaine. Merck was privately owned until going ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
