Vaginal Reconstruction
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Vaginoplasty is any surgical procedure that results in the construction or reconstruction of the
vagina In mammals, the vagina is the elastic, muscular part of the female genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen ...
. It is a type of genitoplasty. Pelvic organ prolapse is often treated with one or more surgeries to repair the vagina. Sometimes a vaginoplasty is needed following the treatment or removal of malignant growths or
abscess An abscess is a collection of pus that has built up within the tissue of the body. Signs and symptoms of abscesses include redness, pain, warmth, and swelling. The swelling may feel fluid-filled when pressed. The area of redness often extends b ...
es in order to restore a normal vaginal structure and function. Surgery to the vagina is done to correct
congenital defect A birth defect, also known as a congenital disorder, is an abnormal condition that is present at childbirth, birth regardless of its cause. Birth defects may result in disability, disabilities that may be physical disability, physical, intellect ...
s to the vagina,
urethra The urethra (from Greek οὐρήθρα – ''ourḗthrā'') is a tube that connects the urinary bladder to the urinary meatus for the removal of urine from the body of both females and males. In human females and other primates, the urethra con ...
and
rectum The rectum is the final straight portion of the large intestine in humans and some other mammals, and the Gastrointestinal tract, gut in others. The adult human rectum is about long, and begins at the rectosigmoid junction (the end of the s ...
. It will correct protrusion of the
urinary bladder The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters ...
into the vagina (
cystocele A cystocele, also known as a prolapsed bladder, is a medical condition in which a woman's bladder bulges into her vagina. Some may have no symptoms. Others may have trouble starting urination, urinary incontinence, or frequent urination. Complicat ...
) and protrusion of the rectum ( rectocele) into the vagina. Often, a vaginoplasty is performed to repair the vagina and its attached structures due to trauma or injury. Labiaplasty, which alters the appearance of the
vulva The vulva (plural: vulvas or vulvae; derived from Latin for wrapper or covering) consists of the external sex organ, female sex organs. The vulva includes the mons pubis (or mons veneris), labia majora, labia minora, clitoris, bulb of vestibu ...
, can be performed as a discrete surgery, or as a subordinate procedure within a vaginoplasty.
Congenital disorder A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can ...
s such as adrenal hyperplasia can affect the structure and function of the vagina and sometimes the vagina is absent; these can be reconstructed or formed, using a vaginoplasty. Other candidates for the surgery include babies born with a microphallus, people with
Müllerian agenesis Müllerian agenesis, also known as Müllerian aplasia, vaginal agenesis, or Mayer-Rokitansky-Küster-Hauser syndrome (MRKH syndrome), is a congenital malformation characterized by a failure of the Müllerian ducts to develop, resulting in a missi ...
resulting in
vaginal hypoplasia Vaginal hypoplasia is the underdevelopment or incomplete development of the vagina. It is a birth defect or congenital abnormality of the female genitourinary system. Signs and symptoms Vaginal hypoplasia can vary in severity from being smaller t ...
,
trans Trans- is a Latin prefix meaning "across", "beyond", or "on the other side of". Used alone, trans may refer to: Arts, entertainment, and media * Trans (festival), a former festival in Belfast, Northern Ireland, United Kingdom * ''Trans'' (film ...
women, and women who have had a vaginectomy after malignancy or trauma. Vaginoplasty can reduce the size of the entrance of the vagina or alter the appearance of the
vulva The vulva (plural: vulvas or vulvae; derived from Latin for wrapper or covering) consists of the external sex organ, female sex organs. The vulva includes the mons pubis (or mons veneris), labia majora, labia minora, clitoris, bulb of vestibu ...
.


Medical uses

Vaginoplasty is the description of the following surgical interventions: * separation of congenitally fused urethra and vagina * repair of a urethra that is short * vaginal construction * vaginal
reconstruction Reconstruction may refer to: Politics, history, and sociology *Reconstruction (law), the transfer of a company's (or several companies') business to a new company *''Perestroika'' (Russian for "reconstruction"), a late 20th century Soviet Union ...
* vaginal vault prolapse * vaginal suspension and fixation * operations on
cul-de-sac A dead end, also known as a cul-de-sac (, from French for 'bag-bottom'), no through road or no exit road, is a street with only one inlet or outlet. The term "dead end" is understood in all varieties of English, but the official terminology ...
* repair of
cystocele A cystocele, also known as a prolapsed bladder, is a medical condition in which a woman's bladder bulges into her vagina. Some may have no symptoms. Others may have trouble starting urination, urinary incontinence, or frequent urination. Complicat ...
and rectocele *
retropubic paravaginal repair A retropubic paravaginal repair is the surgical procedure to reattach the anterior lateral vaginal wall and its connective tissue to its normal position in the pelvis to correct pelvic organ prolapse. It may be necessary to preserve normal funct ...
* the repair of a cystocele using a graft or
prosthesis In medicine, a prosthesis (plural: prostheses; from grc, πρόσθεσις, prósthesis, addition, application, attachment), or a prosthetic implant, is an artificial device that replaces a missing body part, which may be lost through trau ...
* the repair of a cystocele and a rectocele in the same procedure using a graft or prosthetic device * the repair of a rectocele using a graft or prosthetic material * the vaginal construction using a graft or prosthetic material * the vaginal reconstruction using a graft or prosthetic material * the vaginal suspension and stabilization using with graft or prosthetic material * treatment of MRKH syndrome (vaginal agenesis) *
hymenorrhaphy Hymenorrhaphy or hymen reconstruction surgery is the temporary surgical restoration of the hymen. The term comes from the Greek words ''hymen'' meaning "membrane", and ''raphḗ'' meaning "surgical suture, suture". It is also known as ''hymenopla ...
In some instances, extra tissue is needed to reconstruct or construct the vagina. These grafts used in vaginoplasty can be an allogenic, a heterograph, an autograft, xenograft, or an autologous material. A woman can use an autologous in vitro cultured tissue taken from her vaginal vestibule as transplanted tissue to form the lining of the reconstructed vagina. A reconstructed or newly constructed vagina is called a neovagina.


Vaginoplasties in children

Conditions such as
congenital adrenal hyperplasia Congenital adrenal hyperplasia (CAH) is a group of autosomal recessive disorders characterized by impaired cortisol synthesis. It results from the deficiency of one of the five enzymes required for the synthesis of cortisol in the adrenal cortex. ...
virilize genetic females due to a
21-hydroxylase Steroid 21-hydroxylase (also known as steroid 21-monooxygenase, cytochrome P450C21, 21α-hydroxylase and less commonly 21β-hydroxylase) is an enzyme that hydroxylates steroids at the C21 position and is involved in biosynthesis of aldosterone a ...
deficiency. Specific procedures include: clitoral reduction, labiaplasty, normalizing appearance, vagina creation, initiating vaginal dilation. Vaginal atresia, or congenital absence of the vagina, can be another reason for surgery to construct a normal and functional vagina. Vaginoplasty is used as part of the series of surgeries needed to treat those girls and women born with the bladder located outside of their abdomen. After the repairs, women have been able to give birth but are at risk of prolapse. There are human rights concerns about vaginoplasties and other genital surgeries in children who are not old enough to consent, including concern with post-surgical sexual function, and assumptions of cisnormativity.Report of the UN Special Rapporteur on Torture
Office of the UN High Commissioner for Human Rights, February 2013.
There is no consensus attitude amongst clinicians about their necessity, timing, method or evaluation. Vaginoplasties may be performed in children or adolescents with
intersex Intersex people are individuals born with any of several sex characteristics including chromosome patterns, gonads, or genitals that, according to the Office of the United Nations High Commissioner for Human Rights, "do not fit typical bina ...
conditions or
disorders of sex development Disorders of sex development (DSDs), also known as differences in sex development, diverse sex development and variations in sex characteristics (VSC), are congenital conditions affecting the reproductive system, in which development of chromoso ...
.


Techniques

Non-surgical vagina creation was used in the past to treat the
congenital A birth defect, also known as a congenital disorder, is an abnormal condition that is present at birth regardless of its cause. Birth defects may result in disabilities that may be physical, intellectual, or developmental. The disabilities can ...
absence of a vagina. The procedure involved the wearing of a saddle-like device and the use of increasing-diameter dilators. The procedure took several months and was sometimes painful. It was not effective in every instance. Uncommon growths, cysts, septums in the vagina can also require vaginoplasty.


Reconstructive surgery after cancer treatment

Radiological cancer treatment can result in the destruction or alteration of vaginal tissues. Vaginoplasty is often performed to reconstruct the vagina and other genital structures. In some cases, normal sexual function can be restored.


McIndoe surgical technique

A canal is surgically constructed between the
urinary bladder The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters ...
and
urethra The urethra (from Greek οὐρήθρα – ''ourḗthrā'') is a tube that connects the urinary bladder to the urinary meatus for the removal of urine from the body of both females and males. In human females and other primates, the urethra con ...
in the anterior portion of the pelvic region and the
rectum The rectum is the final straight portion of the large intestine in humans and some other mammals, and the Gastrointestinal tract, gut in others. The adult human rectum is about long, and begins at the rectosigmoid junction (the end of the s ...
. A skin graft is used from another area of the person's body. The graft is removed from the
thigh In human anatomy, the thigh is the area between the hip (pelvis) and the knee. Anatomically, it is part of the lower limb. The single bone in the thigh is called the femur. This bone is very thick and strong (due to the high proportion of bone ...
, buttocks, or
inguinal In human anatomy, the inguinal region refers to either the groin or the lower lateral regions of the abdomen. It may also refer to: * Conjoint tendon, previously known as the inguinal aponeurotic falx, a structure formed from the transversus abdo ...
region. Other materials have been used to create the lining of the new vagina. These have been cutaneous skin flaps,
amniotic membrane The amnion is a membrane that closely covers the human and various other embryos when first formed. It fills with amniotic fluid, which causes the amnion to expand and become the amniotic sac that provides a protective environment for the develo ...
s, and buccal mucosa.


Sex reassignment surgery

Several techniques may be used in sex reassignment surgery to create a neovagina.


Penile inversion

Inversion of the penile skin is the method most often selected to create a neovagina by surgeons performing sex reassignment surgery. The inverted penile skin uses inferior pedicle skin or abdominal skin for the lining of the neovagina. The skin is cut to form an appropriate-sized flap. The skin flap is sometimes combined with a scrotal or urethral flap. The penile inversion technique was pioneered by Georges Burou in his Morocco clinic in the 1950s. By the 1970s he had performed hundreds of them, and gave his first public presentation of his technique to a conference at Stanford University in 1973, after which it gradually became the predominant technique worldwide.


Bowel vaginoplasty

Bowel vaginoplasty is another commonly used method to create a neovagina in sex reassignment surgery.


Other methods

Penile-
scrotal The scrotum or scrotal sac is an anatomical male reproductive structure located at the base of the penis that consists of a suspended dual-chambered sac of skin and smooth muscle. It is present in most terrestrial male mammals. The scrotum co ...
skin flaps are also used. Nongenital full-thickness graft (FTG) or split-thickness skin grafts from other parts of the body have been used.


Elective vaginoplasty

Critics have labeled such surgery as the "designer vagina". The American College of Obstetricians and Gynecologists issued a warning against these procedures in 2007 as did the Royal Australian College of Gynaecologists, and a commentary in the ''
British Medical Journal ''The BMJ'' is a weekly peer-reviewed medical trade journal, published by the trade union the British Medical Association (BMA). ''The BMJ'' has editorial freedom from the BMA. It is one of the world's oldest general medical journals. Origi ...
'' strongly criticized the "designer vagina" in 2009. The
Society of Obstetricians and Gynaecologists of Canada The Society of Obstetricians and Gynaecologists of Canada (SOGC) is a national medical society in Canada, representing over 4,000 obstetricians/gynaecologists, family physicians, nurses, midwives, and allied health professionals in the field of ...
published a policy statement against elective vaginoplasty based upon the risks associated with unnecessary cosmetic surgery in 2013. The World Health Organization describes any medically unnecessary surgery to the vaginal tissue and organs as
female genital mutilation Female genital mutilation (FGM), also known as female genital cutting, female genital mutilation/cutting (FGM/C) and female circumcision, is the ritual cutting or removal of some or all of the external female genitalia. The practice is found ...
. Vaginal rejuvenation is a form of elective plastic surgery. Its purpose is to restore or enhance the vagina's cosmetic appearance.


Hymen surgical procedures

An imperforate hymen is the presence of tissue that completely covers the vaginal opening. It is cut to allow menstrual flow to exit during a short surgical procedure. A
hymenorrhaphy Hymenorrhaphy or hymen reconstruction surgery is the temporary surgical restoration of the hymen. The term comes from the Greek words ''hymen'' meaning "membrane", and ''raphḗ'' meaning "surgical suture, suture". It is also known as ''hymenopla ...
is the surgical procedure that reconstructs the hymen.


Balloon vaginoplasty

In this procedure, a Foley catheter is
laparoscopically Laparoscopy () is an operation performed in the abdomen or pelvis using small incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few small cuts in the abdomen.Medli ...
inserted to the rectouterine pouch whereupon gradual traction and distension are applied to create a neovagina.


Pull through or Vecchietti procedure

In treating
Müllerian agenesis Müllerian agenesis, also known as Müllerian aplasia, vaginal agenesis, or Mayer-Rokitansky-Küster-Hauser syndrome (MRKH syndrome), is a congenital malformation characterized by a failure of the Müllerian ducts to develop, resulting in a missi ...
, the Vecchietti procedure is a
laparoscopic Laparoscopy () is an operation performed in the abdomen or pelvis using small incisions (usually 0.5–1.5 cm) with the aid of a camera. The laparoscope aids diagnosis or therapeutic interventions with a few small cuts in the abdomen.Medli ...
surgical technique that produces a
vagina In mammals, the vagina is the elastic, muscular part of the female genital tract. In humans, it extends from the vestibule to the cervix. The outer vaginal opening is normally partly covered by a thin layer of mucosal tissue called the hymen ...
of dimensions (depth and width) comparable to those of a normal vagina (ca. 8.0 cm. deep). A small, plastic sphere called an olive is threaded ( sutured) against the vaginal area; the threads are drawn though the vaginal skin, up through the
abdomen The abdomen (colloquially called the belly, tummy, midriff, tucky or stomach) is the part of the body between the thorax (chest) and pelvis, in humans and in other vertebrates. The abdomen is the front part of the abdominal segment of the torso. ...
, and through the
navel The navel (clinically known as the umbilicus, commonly known as the belly button or tummy button) is a protruding, flat, or hollowed area on the abdomen at the attachment site of the umbilical cord. All placental mammals have a navel, although ...
. There, the threads are attached to a traction device, and then daily are drawn tight so that the olive is pulled inwards and stretches the vagina, by approximately 1.0 cm. per day, thereby creating a vagina, approximately 7.0 cm. deep by 7.0 cm. wide, in 7 days. The mean operating room (OR) time for the Vecchietti vaginoplasty is approximately 45 minutes; yet, depending upon the patient and her indications, the procedure might require more time. The outcomes of Vecchietti technique via the laparoscopic approach are found to be comparable to the procedure using laparotomy. In
vaginal hypoplasia Vaginal hypoplasia is the underdevelopment or incomplete development of the vagina. It is a birth defect or congenital abnormality of the female genitourinary system. Signs and symptoms Vaginal hypoplasia can vary in severity from being smaller t ...
, traction vaginoplasty such as the Vecchietti technique seems to have the highest success rates both anatomically (99%) and functionally (96%) among available treatments. Other surgical techniques that have been developed include ileal neovagina (Monti's technique), the Creatsas vaginoplasty, the Wharton–Sheares–George neovaginoplasty, or the Davydov procedure. The most widely used is the Vecchietti laparoscopic procedure. Sometimes sexual intercourse can result in the dilation of a newly constructed vagina.


Vaginal dilators and expanders

The most techniques of vaginoplasty are using inflatable vaginal expanders or vaginal stents to design the vaginal diameter and length. At the end of the procedure the device stays in place to maintain the neovagina against the pelvic wall which also favors the process of microscopic neovascularization and reduces the risks of hematoma. In post-operative setting the expander can be used regularly to prevent post-operative vaginal retraction. Solid vaginal dilators can also be used immediately after surgery to keep the passage from attachments, and regularly thereafter to maintain the viability of the neovagina. The frequency required to use decreases over time, however remains obligatory lifelong.


Risks and complications

Reconstructive vaginoplasty in children and adolescents carries the risk of " superinfection". In adults, rates and types of complications varied with sex reassignment vaginoplasty.
Necrosis Necrosis () is a form of cell injury which results in the premature death of cells in living tissue by autolysis. Necrosis is caused by factors external to the cell or tissue, such as infection, or trauma which result in the unregulated dige ...
of the clitoral region was 1–3%. Necrosis of the surgically created vagina was 3.7–4.2%. Vaginal shrinkage occurred was documented in 2–10% of those treated. Stricture, or narrowing of the vaginal orifice was reported in 12–15% of the cases. Of those reporting stricture, 41% underwent a second operation to correct the condition. Necrosis of two
scrotal The scrotum or scrotal sac is an anatomical male reproductive structure located at the base of the penis that consists of a suspended dual-chambered sac of skin and smooth muscle. It is present in most terrestrial male mammals. The scrotum co ...
flaps has been described. Posterior vaginal wall is a rare complication.
Genital pain Genital pain and pelvic pain can arise from a variety of conditions, crimes, Major trauma, trauma, medical treatments, physical diseases, mental illness and infections. In some instances the pain is consensual and self-induced. Self-defeating perso ...
was reported in 4–9%. Rectovaginal fistula is also rare with only 1% documented. Vaginal prolapse was seen in 1–2% of people
assigned male at birth Sex assignment (sometimes known as gender assignment) is the discernment of an infant's sex at or before birth. A relative, midwife, nurse or physician inspects the external genitalia when the baby is delivered and, in more than 99.95% of birt ...
undergoing this procedure. The ability of emptying the
bladder The urinary bladder, or simply bladder, is a hollow organ in humans and other vertebrates that stores urine from the kidneys before disposal by urination. In humans the bladder is a distensible organ that sits on the pelvic floor. Urine enters ...
was affected after this procedure with 13% reporting improvement, 68% said that there was no change and 19% reported that voiding got worse. Those reporting a negative outcome experienced in which loss of bladder control and urinary incontinence were 19%.
Urinary tract infection A urinary tract infection (UTI) is an infection that affects part of the urinary tract. When it affects the lower urinary tract it is known as a bladder infection (cystitis) and when it affects the upper urinary tract it is known as a kidney ...
s occurred in 32% of those treated.


See also

* Intersex medical interventions * Sex reassignment surgery (male-to-female) * List of transgender-related topics * Enterocele * Sigmoidocele


References


Bibliography

* * electronic book, no page numbers. {{Reproductive health Gynecological surgery Surgical oncology Surgical removal procedures Reproductive system Gender-affirming surgery (male-to-female) Female genital modification Plastic surgery Vagina Pediatric gynecology Chromosomes Urethra disorders Female genital mutilation Intersex and medicine