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Tonic water (or Indian tonic water) is a
carbonated soft drink A soft drink (see § Terminology for other names) is a drink that usually contains water (often carbonated), a sweetener, and a natural and/or artificial flavoring. The sweetener may be a sugar, high-fructose corn syrup, fruit juice, a s ...
in which
quinine Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cr ...
is dissolved. Originally used as a
prophylactic Preventive healthcare, or prophylaxis, consists of measures taken for the purposes of disease prevention.Hugh R. Leavell and E. Gurney Clark as "the science and art of preventing disease, prolonging life, and promoting physical and mental hea ...
against
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
, tonic water usually has a significantly lower quinine content and is consumed for its distinctive bitter flavor, though nowadays it is often sweetened. It is frequently used in
mixed drink A mixed drink is a beverage in which two or more ingredients are mixed. Types * List of non-alcoholic mixed drinks -- A non-alcoholic mixed drink (also known as virgin cocktail, boneless cocktail, temperance drink, or mocktail) is a cocktail-st ...
s, particularly in
gin and tonic A gin and tonic is a highball cocktail made with gin and tonic water poured over a large amount of ice. The ratio of gin to tonic varies according to taste, strength of the gin, other drink mixers being added, etc., with most recipes calling f ...
.


History

As early as the 17th century the Spanish used quinine from the bark of
Cinchona ''Cinchona'' (pronounced or ) is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. All are native to the Tropical Andes, tropical Andean forests of western South America. A few species are ...
trees to treat malaria after being shown the remedy from the Indigenous peoples of Peru, Bolivia, and Ecuador. In early 19th century
India India, officially the Republic of India (Hindi: ), is a country in South Asia. It is the seventh-largest country by area, the second-most populous country, and the most populous democracy in the world. Bounded by the Indian Ocean on the so ...
and other tropical posts of the
British Empire The British Empire was composed of the dominions, colonies, protectorates, mandates, and other territories ruled or administered by the United Kingdom and its predecessor states. It began with the overseas possessions and trading posts esta ...
, medicinal quinine was recommended to British officials and soldiers to prevent
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
, where it was mixed with soda and sugar to mask its bitter taste, creating tonic water. The first commercial tonic water was produced in 1858 when it was patented by the owner of Pitt & Co., Erasmus Bond. The mixed drink
gin and tonic A gin and tonic is a highball cocktail made with gin and tonic water poured over a large amount of ice. The ratio of gin to tonic varies according to taste, strength of the gin, other drink mixers being added, etc., with most recipes calling f ...
also originated in
British colonial India The British Raj (; from Hindi ''rāj'': kingdom, realm, state, or empire) was the rule of the British Crown on the Indian subcontinent; * * it is also called Crown rule in India, * * * * or Direct rule in India, * Quote: "Mill, who was himsel ...
, when the British mixed their medicinal quinine tonic with gin and other ingredients to make the bitter medicine more palatable. Soldiers in India were already given a gin ration, so the sweet concoction was easy to make. In 1868 the first known record of a gin and tonic was in the “Oriental Sporting Magazine” and was described as a refreshing cocktail for spectators of horse racing, not as a medicine.


Quinine content

Medicinal tonic water originally contained only
carbonated water Carbonated water (also known as soda water, sparkling water, fizzy water, club soda, water with gas, in many places as mineral water, or especially in the United States as seltzer or seltzer water) is water containing dissolved carbon dioxide gas, ...
and a large amount of quinine. Most modern tonic waters contain comparatively less quinine, and are often enhanced by citrus flavors. As a result of the lower quinine content, tonic water is less bitter. It is also usually sweetened, often with the addition of
high-fructose corn syrup High-fructose corn syrup (HFCS), also known as glucose–fructose, isoglucose and glucose–fructose syrup, is a sweetener made from corn starch. As in the production of conventional corn syrup, the starch is broken down into glucose by enzy ...
or sugar. Some manufacturers also produce diet (or "slimline") tonic water, which may contain artificial sweeteners such as
aspartame Aspartame is an artificial non-saccharide sweetener 200 times sweeter than sucrose and is commonly used as a sugar substitute in foods and beverages. It is a methyl ester of the aspartic acid/phenylalanine dipeptide with the trade names ...
. Traditional-style tonic water with high amounts of quinine and carbonated water is less common, but may be preferred by those who desire the bitter flavor. In the United States, the US
Food and Drug Administration The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is respon ...
(FDA) limits the quinine content in tonic water to 83 ppm (83mg per liter), while the daily therapeutic dose of quinine is in the range of 500–1000mg, and 10mg/kg every eight hours for effective malaria prevention (2100mg daily for a adult). It is often recommended as a relief for leg
cramp A cramp is a sudden, involuntary, painful skeletal muscle contraction or overshortening associated with electrical activity; while generally temporary and non-damaging, they can cause significant pain and a paralysis-like immobility of the aff ...
s, but medical research suggests some care is needed in monitoring doses. Because of quinine's risks, the FDA cautions consumers against using "off-label" quinine drugs to treat leg cramps.


Use

Tonic water is often used as a
drink mixer Drink mixers are the non-alcoholic ingredients in mixed drinks and cocktails. Mixers dilute the drink, lowering the alcohol by volume in the drink. They change, enhance, or add new flavors to a drink. They may make the drink sweeter, more sour ...
for
cocktail A cocktail is an alcoholic mixed drink. Most commonly, cocktails are either a combination of spirits, or one or more spirits mixed with other ingredients such as tonic water, fruit juice, flavored syrup, or cream. Cocktails vary widely across ...
s, especially
gin and tonic A gin and tonic is a highball cocktail made with gin and tonic water poured over a large amount of ice. The ratio of gin to tonic varies according to taste, strength of the gin, other drink mixers being added, etc., with most recipes calling f ...
.
Vodka tonic A vodka tonic is a cocktail made with varying proportions of vodka and tonic water. Vodka tonics are frequently garnished with a slice of lime or lemon. One commonly used recipe is one part vodka and one part tonic water in a tumbler, often a h ...
is also popular. Tonic water with
lemon The lemon (''Citrus limon'') is a species of small evergreen trees in the flowering plant family Rutaceae, native to Asia, primarily Northeast India (Assam), Northern Myanmar or China. The tree's ellipsoidal yellow fruit is used for culin ...
or
lime Lime commonly refers to: * Lime (fruit), a green citrus fruit * Lime (material), inorganic materials containing calcium, usually calcium oxide or calcium hydroxide * Lime (color), a color between yellow and green Lime may also refer to: Botany ...
juice added is often known as
bitter lemon Bitter lemon is a bitter lemon flavoured soft drink. Its signature taste is a result of inherently bitter lemon pith being reinforced by the bitter alkaloid quinine. The principal difference between tonic water and bitter lemon is the lemon ...
or bitter lime. It is popular for its signature bitter but sweet taste. Another use of tonic water is in coffee. The ''espresso & tonic'' was created in Helsingborg, Sweden at Koppi Roasters after a staff party where they mixed tonic water, syrup, and an espresso. Since 2007, the drink has grown in popularity in Scandinavia, Europe, and the United States.


Negative effects

Tonic water is known to cause fixed eruptions, which is a type of skin reaction to drugs, due to the quinine content. Various scientific journals have reported the repeated intake of tonic water can cause fixed eruptions with varying severity, with one reporting the onset of
Stevens–Johnson syndrome Stevens–Johnson syndrome (SJS) is a type of severe skin reaction. Together with toxic epidermal necrolysis (TEN) and Stevens–Johnson/toxic epidermal necrolysis (SJS/TEN), it forms a spectrum of disease, with SJS being less severe. Erythema ...
. The cases of fixed eruptions were seen after the patients drank tonic water, by itself or mixed with gin. Some symptoms of the fixed eruptions include pigmented macules, high fever, erythematous plaques, and bullous. There is a higher chance of reaction if someone has an abnormal heart rhythm or low blood sugar, is pregnant, or has kidney or liver diseases.


Fluorescence

The quinine in tonic water will
fluoresce Fluorescence is the emission of light by a substance that has absorbed light or other electromagnetic radiation. It is a form of luminescence. In most cases, the emitted light has a longer wavelength, and therefore a lower photon energy, tha ...
under
ultraviolet light Ultraviolet (UV) is a form of electromagnetic radiation with wavelength from 10 nm (with a corresponding frequency around 30  PHz) to 400 nm (750  THz), shorter than that of visible light, but longer than X-rays. UV radiation i ...
. In fact, quinine will visibly fluoresce in direct sunlight against a dark background. The quinine molecules release energy as light instead of heat, which is more common. The state is not stable and the molecules will eventually return to a ground state and no longer glow.


See also

*
Água de Inglaterra ''Água de Inglaterra'' (“Water of England” or “English Water”) was an example of the 'secret remedies' that were in vogue in Portugal during the 18th century. The name was used for various pharmaceutical preparations produced by several m ...


References


External links

* * {{Authority control Carbonated water Drink mixers Quinine Soft drinks Products introduced in 1858