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Água De Inglaterra
''Água de Inglaterra'' (“Water of England” or “English Water”) was an example of the 'secret remedies' that were in vogue in Portugal during the 18th century. The name was used for various pharmaceutical preparations produced by several manufacturers from the end of the 17th century to the beginning of the 19th. In addition to the name, these preparations had in common the fact that the major therapeutic ingredient was the bark of the cinchona tree, from which quinine is obtained. Reference to the drug can be found in all Portuguese Pharmacopeias between 1681 and 1821. History ''Água de Inglaterra'' was used for the treatment of malaria, which at the time was endemic in several regions of Portugal, including the Sado River valley and the Guadiana river. It was initially introduced from England in 1681 by Dr. Fernando Mendes, who “received a handsome gift from ( King Dom Pedro) on condition that he should reveal to him the secret of his composition and withhold it from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cinchona
''Cinchona'' (pronounced or ) is a genus of flowering plants in the family Rubiaceae containing at least 23 species of trees and shrubs. All are native to the Tropical Andes, tropical Andean forests of western South America. A few species are reportedly naturalization (biology), naturalized in Central America, Jamaica, French Polynesia, Sulawesi, Saint Helena in the South Atlantic, and São Tomé and Príncipe off the coast of tropical Africa, and others have been cultivated in India and Java, where they have formed hybrids. ''Cinchona'' has been historically sought after for its medicinal value, as the bark of several species yields quinine and other alkaloids. These were the only effective treatments against malaria during the height of European colonialism, which made them of great economic and political importance. Trees in the genus are also known as fever trees because of their anti-malarial properties. The artificial Quinine total synthesis, synthesis of quinine in 1944 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quinine
Quinine is a medication used to treat malaria and babesiosis. This includes the treatment of malaria due to ''Plasmodium falciparum'' that is resistant to chloroquine when artesunate is not available. While sometimes used for nocturnal leg cramps, quinine is not recommended for this purpose due to the risk of serious side effects. It can be taken by mouth or intravenously. Malaria resistance to quinine occurs in certain areas of the world. Quinine is also used as an ingredient in tonic water to impart a bitter taste. Common side effects include headache, ringing in the ears, vision issues, and sweating. More severe side effects include deafness, low blood platelets, and an irregular heartbeat. Use can make one more prone to sunburn. While it is unclear if use during pregnancy causes harm to the baby, treating malaria during pregnancy with quinine when appropriate is still recommended. Quinine is an alkaloid, a naturally occurring chemical compound. How it works as a medicin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacopeia
A pharmacopoeia, pharmacopeia, or pharmacopoea (from the obsolete typography ''pharmacopœia'', meaning "drug-making"), in its modern technical sense, is a book containing directions for the identification of compound medicines, and published by the authority of a government or a medical or pharmaceutical society. Descriptions of preparations are called monographs. In a broader sense it is a reference work for pharmaceutical drug specifications. Etymology The term derives from grc, φαρμακοποιία ''pharmakopoiia'' "making of (healing) medicine, drug-making", a compound of φάρμακον ''pharmakon'' "healing medicine, drug, poison", the verb ποιεῖν ''poiein'' "to make" and the abstract noun suffix -ία ''-ia''. In early modern editions of Latin texts, the Greek diphthong οι (''oi'') is latinized to its Latin equivalent ''oe'' which is in turn written with the ligature ''œ'', giving the spelling ''pharmacopœia''; in modern UK English, ''œ'' is writ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sado River
The river Sado () is a river in southern Portugal; it is one of the major rivers in the country. It flows in a northerly direction (the only major Portuguese river to do so) through from its springs in the hills of Ourique before entering the Atlantic Ocean in an estuary in the city of Setúbal. The estuary is the habitat of a large community of bottlenose dolphins; there are 31 members of the pod, each of whom has been named (2007). The river is dammed in several places, chiefly for irrigation of rice, maize, and other vegetables. In its course, the river crosses the city of Alcácer do Sal Alcácer do Sal () is a municipality in Portugal, located in Setúbal District. The population in 2011 was 13,046, in an area of 1499.87 km2. History Earliest settlement There has been human settlement in the area for more than 40,000 ye .... References Rivers of Portugal {{Portugal-river-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Guadiana
The Guadiana River (, also , , ), or Odiana, is an international river defining a long stretch of the Portugal-Spain border, separating Extremadura and Andalusia (Spain) from Alentejo and Algarve (Portugal). The river's basin extends from the eastern portion of Extremadura to the southern provinces of the Algarve; the river and its tributaries flow from east to west, then south through Portugal to the border towns of Vila Real de Santo António (Portugal) and Ayamonte (Spain), where it flows into the Gulf of Cádiz. With a course that covers a distance of , it is the fourth-longest in the Iberian peninsula, and its hydrological basin extends over an area of approximately (the majority of which lies within Spain). Etymology The Romans referred to the river as the , the "River of Ducks". During the Moorish occupation and settlement, the name was extended and referred to as ''Wadi Ana'' (''wādī'' being the Arab term for "river"), later passed on to Portuguese and Spanish settle ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peter II Of Portugal
''Dom'' Pedro II (Peter II; 26 April 1648 – 9 December 1706), nicknamed "the Pacific", was King of Portugal from 1683 until his death, previously serving as regent for his brother Afonso VI from 1668 until his own accession. He was the fifth and last child of John IV and Luisa de Guzmán. Early life Third son of King John IV and Queen Luisa, Peter was created Duke of Beja and Lord of the House of the Infantado. Following his father's death, his mother became regent for the new king Afonso VI, Peter's elder, partially paralysed, and mentally unstable brother. In 1662 Afonso put his mother away in a convent and assumed control of the state. In January 1668, shortly before Spanish recognition of Portugal's restoration of independence, Peter acquired political ascendancy over his brother and was appointed regent, banishing Afonso to the Azores and, later, Sintra where he died in 1683. Peter thereupon inherited the throne. Peter not only inherited his brother's throne but also ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jacob De Castro Sarmento
Jacob Henriques de Castro Sarmento (6 May 1690 in Bragança, Portugal – 14 September 1762 in London) was a Portuguese ''estrangeirado'', physician, naturalist, poet and Deist. Life At the age of seventeen he entered the University of Évora to study philosophy, and later studied medicine at Coimbra, receiving his baccalaureate in 1717. In order to escape the persecutions of the Portuguese Inquisition, Henrique — so-called as a Marrano — went into voluntary exile in London in 1720. There he continued his studies in medicine, physics, and chemistry, and passed his examinations in the theory and practice of medicine. He became a member of the Royal College of Physicians and was elected a fellow of the Royal Society of London in 1730, in recognition of his having introduced a new medicine for curing fevers. Castro Sarmento married Elizabeth, a non-Jew and converted to Anglicanism, although he was not baptized. Career Learning about quinine in London, Castro Sarm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by King Charles II as The Royal Society and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the Society's President, according to a set of statutes and standing orders. The members of Council and the President are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John VI Of Portugal
, house = Braganza , father = Peter III of Portugal , mother = Maria I of Portugal , birth_date = , birth_place = Queluz Palace, Queluz, Portugal , death_date = , death_place = Bemposta Palace, Lisbon, Portugal , burial_date = , burial_place = Pantheon of the House of Braganza , signature = Assinatura D. João VI.svg , religion = Roman Catholicism Dom John VI (Portuguese: ''João VI''; 13 May 1767 – 10 March 1826), nicknamed "the Clement", was King of the United Kingdom of Portugal, Brazil and the Algarves from 1816 to 1825. Although the United Kingdom of Portugal ceased to exist ''de facto'' beginning in 1822, he remained its monarch ''de jure'' between 1822 and 1825. After the recognition of the independence of Brazil under the Treaty of Rio de Janeiro of 1825, he continued as King of Portugal until his death in 1826. Under the same treaty, he also became titular Emperor of Brazil for life, while his son, Emperor Dom Pedr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pierre Joseph Pelletier
Pierre-Joseph Pelletier (, , ; 22 March 1788 – 19 July 1842) was a French chemist and pharmacist who did notable research on vegetable alkaloids, and was the co-discoverer with Joseph Bienaimé Caventou of quinine, caffeine, and strychnine. He was also a collaborator and co-author with Polish chemist Filip Walter. See also * Joseph Bienaimé Caventou Joseph Bienaimé Caventou (30 June 1795 – 5 May 1877) was a French pharmacist. He was a professor at the École de Pharmacie (School of Pharmacy) in Paris. He collaborated with Pierre-Joseph Pelletier in a Parisian laboratory located behind an ... * Filip Nariusz Walter References Further reading * Scientists from Paris 1788 births 1842 deaths French Roman Catholics 19th-century French chemists French biochemists Members of the French Academy of Sciences {{france-chemist-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Joseph Bienaimé Caventou
Joseph Bienaimé Caventou (30 June 1795 – 5 May 1877) was a French pharmacist. He was a professor at the École de Pharmacie (School of Pharmacy) in Paris. He collaborated with Pierre-Joseph Pelletier in a Parisian laboratory located behind an apothecary. He was a pioneer in the use of mild solvents to isolate a number of active ingredients from plants, making a study of alkaloids from vegetables. Among their successes were the isolation of the following compounds: Quinine sulfate later proved to be an important remedy for the disease malaria. Quinine is the active anti-malarial ingredient in the bark of cinchona tree. Neither of the partners chose to patent their discovery of this compound, releasing it for everybody to use. In 1823 they discovered nitrogen in alkaloid compounds. Other compounds they discovered include colchicine and veratrine. The crater Caventou on the Moon The Moon is Earth's only natural satellite. It is the fifth largest satellite in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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