Scott A. Strobel (born July 4, 1964) is the provost,

Henry Ford II Henry Ford II (September 4, 1917 – September 29, 1987), sometimes known as "Hank the Deuce", was an American businessman in the automotive industry. He was the oldest son of Edsel Ford I and oldest grandson of Henry Ford I. He was president ...

professor Professor (commonly abbreviated as Prof.) is an Academy, academic rank at university, universities and other post-secondary education and research institutions in most countries. Literally, ''professor'' derives from Latin as a "person who pr ...

of molecular

biophysics Biophysics is an interdisciplinary science that applies approaches and methods traditionally used in physics to study biological phenomena. Biophysics covers all scales of biological organization, from molecular to organismic and populations. ...

and

biochemistry Biochemistry or biological chemistry is the study of chemical processes within and relating to living organisms. A sub-discipline of both chemistry and biology, biochemistry may be divided into three fields: structural biology, enzymology and ...

, and a professor of

chemistry Chemistry is the science, scientific study of the properties and behavior of matter. It is a natural science that covers the Chemical element, elements that make up matter to the chemical compound, compounds made of atoms, molecules and ions ...

Yale University Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the wo ...

. He was the vice provost for Science Initiatives and vice president for West Campus Planning & Program Development. An educator and researcher, he has led a number of Yale initiatives over the past two decades. Strobel was appointed as Yale's provost in 2020.

Career

Strobel earned a

bachelor's degree A bachelor's degree (from Middle Latin ''baccalaureus'') or baccalaureate (from Modern Latin ''baccalaureatus'') is an undergraduate academic degree awarded by colleges and universities upon completion of a course of study lasting three to six ...

in biochemistry from

Brigham Young University Brigham Young University (BYU, sometimes referred to colloquially as The Y) is a private research university in Provo, Utah. It was founded in 1875 by religious leader Brigham Young and is sponsored by the Church of Jesus Christ of Latter-day ...

and a

Ph.D. A Doctor of Philosophy (PhD, Ph.D., or DPhil; Latin: or ') is the most common degree at the highest academic level awarded following a course of study. PhDs are awarded for programs across the whole breadth of academic fields. Because it is a ...

in biology from the

California Institute of Technology The California Institute of Technology (branded as Caltech or CIT)The university itself only spells its short form as "Caltech"; the institution considers other spellings such a"Cal Tech" and "CalTech" incorrect. The institute is also occasional ...

, under the guidance of Peter Dervan, before doing

postdoctoral A postdoctoral fellow, postdoctoral researcher, or simply postdoc, is a person professionally conducting research after the completion of their doctoral studies (typically a PhD). The ultimate goal of a postdoctoral research position is to p ...

research at the

University of Colorado, Boulder The University of Colorado Boulder (CU Boulder, CU, or Colorado) is a public research university in Boulder, Colorado. Founded in 1876, five months before Colorado became a state, it is the flagship university of the University of Colorado syst ...

, under the mentorship of

Thomas Cech Thomas Robert Cech (born December 8, 1947) is an American chemist who shared the 1989 Nobel Prize in Chemistry with Sidney Altman, for their discovery of the catalytic properties of RNA. Cech discovered that RNA could itself cut strands of RNA, ...

. He has been a professor with the

Howard Hughes Medical Institute The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization based in Chevy Chase, Maryland. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, fil ...

(HHMI) since 2006. He joined the Yale faculty in 1995 in the Department of Molecular Biophysics & Biochemistry and served as department chair from 2006 to 2009. Since 2011 he has served as vice president for West Campus Planning & Program Development, where he has directed the expansion of the West Campus as a research and educational center. In 2014 he also became the inaugural deputy provost for Teaching & Learning. In this capacity he has overseen the creation of the Yale Poorvu Center for Teaching and Learning, housed within the

Sterling Memorial Library Sterling Memorial Library (SML) is the main library building of the Yale University Library system in New Haven, Connecticut, United States. Opened in 1931, the library was designed by James Gamble Rogers as the centerpiece of Yale's Gothic Revi ...

. The center provides teaching resources and support to Yale faculty, postdocs, graduate students and undergraduate students.

Research and Teaching

Strobel's research focuses on the biophysics and biochemistry of catalytic

RNAs The Royal Naval Air Service (RNAS) was the air arm of the Royal Navy, under the direction of the Admiralty's Air Department, and existed formally from 1 July 1914 to 1 April 1918, when it was merged with the British Army's Royal Flying Corps t ...

, including

riboswitches In molecular biology, a riboswitch is a regulatory segment of a messenger RNA molecule that binds a small molecule, resulting in a change in Translation (biology), production of the proteins encoded by the mRNA. Thus, an mRNA that contains a ribo ...

and

peptidyl transferase The peptidyl transferase is an aminoacyltransferase () as well as the primary enzymatic function of the ribosome, which forms peptide bonds between adjacent amino acids using tRNAs during the translation process of protein biosynthesis. The subst ...

. His group developed the early methods of

Nucleotide Analog Interference Mapping Experimental approaches of determining the Biomolecular structure, structure of nucleic acids, such as RNA and DNA, can be largely classified into biophysics, biophysical and biochemistry, biochemical methods. Biophysical methods use the fundamen ...

, used to determine the importance of particular functional groups in a structured RNA molecule. Strobel's group solved the x-ray crystal structure of the full length ''

Azoarcus ''Azoarcus'' is a genus of nitrogen-fixing bacteria. Species in this genus are usually found in contaminated water, as they are involved in the degradation of some contaminants, commonly inhabiting soil. These bacteria have also been found growin ...

Group I catalytic intron Group I introns are large self-splicing ribozymes. They catalyze their own excision from mRNA, tRNA and rRNA precursors in a wide range of organisms. The core secondary structure consists of nine paired regions (P1-P9). These fold to essentially ...

,Yale Scientists Visualize Molecular Detail Of RNA Splicing Complex
(June 3, 2004). ''

ScienceDaily ''Science Daily'' is an American website launched in 1995 that aggregates press releases and publishes lightly edited press releases (a practice called churnalism) about science, similar to Phys.org and EurekAlert!. The site was founded by mar ...

'' Retrieved October 16, 2012 the glmS ribozyme, and the c-di-GMP riboswitch. He has also collaborated with the Thomas A. Steitz lab at Yale on structural studies toward better understanding the mechanism of

ribosomal Ribosomes ( ) are macromolecular machines, found within all cells, that perform biological protein synthesis (mRNA translation). Ribosomes link amino acids together in the order specified by the codons of messenger RNA (mRNA) molecules to fo ...

peptide synthesis In organic chemistry, peptide synthesis is the production of peptides, compounds where multiple amino acids are linked via amide bonds, also known as peptide bonds. Peptides are chemically synthesized by the condensation reaction of the carboxyl ...

. He was twice named a HHMI professor to promote undergraduate science education. With this award he instituted an undergraduate research course, the Rainforest Expedition and Laboratory, which explored microbial and chemical diversity in the world's rainforests as a means to inspire undergraduate students in the sciences. He has led groups of undergraduate students into the rainforest over spring break to hunt for novel

endophytes An endophyte is an endosymbiont, often a bacterium or fungus, that lives within a plant for at least part of its life cycle without causing apparent disease. Endophytes are ubiquitous and have been found in all species of plants studied to date; h ...

that live inside plants. Following fieldwork, students then isolated microbes and tested them for interesting properties, discovering a variety of organisms including novel fungi with new biological and chemical properties, including ''

Pestalotiopsis microspora ''Pestalotiopsis microspora'' is a species of endophytic fungus capable of breaking down and digesting polyurethane. Originally identified in 1880 in fallen foliage of common ivy (''Hedera helix'') in Buenos Aires, it also causes leaf spot in ...

'', of which some strains degrade

polyurethane Polyurethane (; often abbreviated PUR and PU) refers to a class of polymers composed of organic chemistry, organic units joined by carbamate (urethane) links. In contrast to other common polymers such as polyethylene and polystyrene, polyurethan ...

Awards and honors

Strobel has received Beckman, Searle and Basil O'Connor career awards. He received the Dylan Hixon Prize for Teaching Excellence in the Natural Sciences. He also received the Yale Graduate Mentoring Award in the Sciences. He received the Yale Science and Engineering Association Award for Meritorious Service to Yale University.

Personal

Strobel and his son run a small hobby business crafting remnants of campus trees into various

lathe A lathe () is a machine tool that rotates a workpiece about an axis of rotation to perform various operations such as cutting, sanding, knurling, drilling, deformation, facing, and turning, with tools that are applied to the workpiece to c ...

d items.

References

External links

Howard Hughes Medical Institute bioStrobel Lab websiteYale West CampusYale Poorvu Center for Teaching and Learning
{{DEFAULTSORT:Strobel, Scott Living people American biochemists Howard Hughes Medical Investigators Yale University faculty Brigham Young University alumni California Institute of Technology alumni 1964 births