Richard Lounsbery Award
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The Richard Lounsbery Award is given to
American American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, pe ...
and French
scientist A scientist is a person who conducts Scientific method, scientific research to advance knowledge in an Branches of science, area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, ...
s, 45 years or younger, in recognition of "extraordinary scientific achievement in
biology Biology is the scientific study of life. It is a natural science with a broad scope but has several unifying themes that tie it together as a single, coherent field. For instance, all organisms are made up of cells that process hereditary i ...
and
medicine Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care pract ...
." The Award alternates between French and American scientists, and is awarded by the
National Academy of Sciences The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the Nati ...
and the
French Academy of Sciences The French Academy of Sciences (French: ''Académie des sciences'') is a learned society, founded in 1666 by Louis XIV of France, Louis XIV at the suggestion of Jean-Baptiste Colbert, to encourage and protect the spirit of French Scientific me ...
in alternating years to a scientist from the other country. The award is selected by a seven-member jury representing both the French and the US Academies. The recipient receives a $75,000 prize, funding to visit a lab or research institution in the awarding country, and an invitation to give the Lounsbery Lecture in the awarding country. The Lounsbery Award was established in 1979 by Vera Lounsbery in memory of her husband,
Richard Lounsbery Richard Lounsbery (born in New York City in 1882, died 1967) was an American businessman. The Richard Lounsbery Foundation was set up with his family's wealth. Early life Lounsbery was born in New York City in 1882 into an affluent family. His ...
, and is funded by the Richard Lounsbery Foundation. Richard and Vera met in Paris after
World War I World War I (28 July 1914 11 November 1918), often abbreviated as WWI, was one of the deadliest global conflicts in history. Belligerents included much of Europe, the Russian Empire, the United States, and the Ottoman Empire, with fightin ...
, and the couple divided their time between
Paris Paris () is the capital and most populous city of France, with an estimated population of 2,165,423 residents in 2019 in an area of more than 105 km² (41 sq mi), making it the 30th most densely populated city in the world in 2020. S ...
and
New York New York most commonly refers to: * New York City, the most populous city in the United States, located in the state of New York * New York (state), a state in the northeastern United States New York may also refer to: Film and television * '' ...
.


Award recipients

Source: *2022
Claire Wyart Claire Julie Liliane Wyart (born 16 February 1977) is a French neuroscientist and biophysicist, studying the circuits underlying the control of locomotion. She is a chevalier of the Ordre national du Mérite. Early life Wyart was born into a f ...
, for her outstanding research on the sensory interface between the central nervous system and cerebrospinal fluid that controls our posture and movements. *2021
Feng Zhang Feng Zhang (; born October 22, 1981) is a Chinese-American biochemist. Zhang currently holds the James and Patricia Poitras Professorship in Neuroscience at the McGovern Institute for Brain Research and in the departments of Brain and Cognitive ...
, for his pioneering achievements in the field of genome editing, including the discovery of novel CRISPR systems and their development as molecular tools. *2020 , for her work in developmental biology, in particular training and evolution of periodic patterns on the plumage of birds. *2019 Jay Shendure, for his pioneering work and leadership in the second wave of genomics that is transforming genetics and medicine. Through his development of exome sequencing and other novel technologies, he has defined new paradigms for implicating Mendelian disease genes, interpreting genetic variation, and single cell profiling of developmental lineages and gene regulation in whole organisms. *2018 , For his work on the genetic and mechanical regulation that underlies tissue proliferation, homeostasis and repair in physiological and pathological conditions (using a combination of interdisciplinary approaches involving sophisticated imaging, genetics, large-scale molecular approaches, and computational analyses) including the mechanisms of local and long-range mechano-sensing during cytokinesis that remodel the dividing cell adherens junction. *2017 Pardis Sabeti, for her contributions to global health and study of emerging diseases and
pandemics A pandemic () is an epidemic of an infectious disease that has spread across a large region, for instance multiple continents or worldwide, affecting a substantial number of individuals. A widespread endemic disease with a stable number of in ...
, including
ebola Ebola, also known as Ebola virus disease (EVD) and Ebola hemorrhagic fever (EHF), is a viral hemorrhagic fever in humans and other primates, caused by ebolaviruses. Symptoms typically start anywhere between two days and three weeks after becom ...
,
Lassa fever Lassa fever, also known as Lassa hemorrhagic fever (LHF), is a type of viral hemorrhagic fever caused by the Lassa virus. Many of those infected by the virus do not develop symptoms. When symptoms occur they typically include fever, weakness, ...
, and
malaria Malaria is a mosquito-borne infectious disease that affects humans and other animals. Malaria causes symptoms that typically include fever, tiredness, vomiting, and headaches. In severe cases, it can cause jaundice, seizures, coma, or death. S ...
*2016 , for his work in Structural Biology (by X-ray diffraction and cryo-electron microscopy methods) on the regulation of gene expression at both the transcriptional level (structures of the nuclear receptors to retinoic acid and vitamin D) and the protein translation level (initiation and termination complexes, and the structure of the human ribosome). *2015
Hopi Hoekstra Danielle "Hopi" Elizabeth Hoekstra (born 1972) is an evolutionary biology, evolutionary biologist working at Harvard University in Cambridge, Massachusetts and serving as the Dean of its Harvard Faculty of Arts and Sciences, Faculty of Arts and S ...
, for her work probing the molecular basis of how adaptation to novel selective pressures establishes and sustains diversity during
evolution Evolution is change in the heritable characteristics of biological populations over successive generations. These characteristics are the expressions of genes, which are passed on from parent to offspring during reproduction. Variation ...
. *2014 , for his major contributions to the understanding of molecular and cellular mechanisms causing
Huntington's disease Huntington's disease (HD), also known as Huntington's chorea, is a neurodegenerative disease that is mostly inherited. The earliest symptoms are often subtle problems with mood or mental abilities. A general lack of coordination and an unst ...
. *2013
Karl Deisseroth Karl Alexander Deisseroth (born November 18, 1971) is an American scientist. He is the D.H. Chen Professor of Bioengineering and of psychiatry and behavioral sciences at Stanford University. He is known for creating and developing the technolo ...
, for pioneering the technology called
optogenetics Optogenetics is a biological technique to control the activity of neurons or other cell types with light. This is achieved by expression of light-sensitive ion channels, pumps or enzymes specifically in the target cells. On the level of individu ...
in which insertion of a single
bacterial Bacteria (; singular: bacterium) are ubiquitous, mostly free-living organisms often consisting of one biological cell. They constitute a large domain of prokaryotic microorganisms. Typically a few micrometres in length, bacteria were among ...
protein into a
neuron A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. N ...
allows exquisite control of the neuron with light. *2012 , for his work in embryonic patterning in
vertebrates Vertebrates () comprise all animal taxa within the subphylum Vertebrata () ( chordates with backbones), including all mammals, birds, reptiles, amphibians, and fish. Vertebrates represent the overwhelming majority of the phylum Chordata, ...
and particularly in the genetic and developmental mechanisms that control segmentation. *2011 Bonnie L. Bassler, for her pioneering discoveries of the universal use of chemical communication among bacteria and the elucidation of structural and regulatory mechanisms controlling bacterial assemblies. *2010 Gérard Karsenty, for his work on the molecular mechanisms that underlie the formation and the remodeling of bone. *2009 Cornelia I. Bargmann, for her extraordinarily inventive and successful use of molecular and classical genetics to probe the individual nerve cell basis of behavior in
C. elegans ''Caenorhabditis elegans'' () is a free-living transparent nematode about 1 mm in length that lives in temperate soil environments. It is the type species of its genus. The name is a blend of the Greek ''caeno-'' (recent), ''rhabditis'' (r ...
. *2008 , for his contributions to the understanding the genetic basis of the predisposition to viral and bacterial diseases of childhood, which have important clinical implications for the diagnostic and management of infectious diseases. *2007 Xiaodong Wang, for his pioneering biochemical studies on
apoptosis Apoptosis (from grc, ἀπόπτωσις, apóptōsis, 'falling off') is a form of programmed cell death that occurs in multicellular organisms. Biochemical events lead to characteristic cell changes (morphology) and death. These changes incl ...
, which have elucidated a molecular pathway leading into and out of the
mitochondrion A mitochondrion (; ) is an organelle found in the cells of most Eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used ...
and to the
nucleus Nucleus ( : nuclei) is a Latin word for the seed inside a fruit. It most often refers to: *Atomic nucleus, the very dense central region of an atom *Cell nucleus, a central organelle of a eukaryotic cell, containing most of the cell's DNA Nucle ...
. *2006 Catherine Dulac, for her major contributions in the perception and behavioral translation of
pheromones A pheromone () is a secreted or excreted chemical factor that triggers a social response in members of the same species. Pheromones are chemicals capable of acting like hormones outside the body of the secreting individual, to affect the behavio ...
in mammals. *2005 John Kuriyan, for his critical role in revealing the structural mechanisms underlying processivity in DNA replication and the regulation of
tyrosine kinases A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as an "on" or "off" switch in many cellular functions. Tyrosine kinases belong to a larger cla ...
and their interacting target proteins. *2004 Brigitte Kieffer, for her pioneering work on the molecular neurobiology of opioid-controlled behaviors, the results of which have very important implications for the treatment of pain, drug abuse, and emotional disorders. *2003
Carol W. Greider Carolyn Widney Greider (born April 15, 1961) is an American molecular biologist and Nobel laureate. She joined the University of California, Santa Cruz as a Distinguished Professor in the department of molecular, cell, and developmental biology ...
, for her pioneering biochemical and genetic studies of
telomerase Telomerase, also called terminal transferase, is a ribonucleoprotein that adds a species-dependent telomere repeat sequence to the 3' end of telomeres. A telomere is a region of repetitive sequences at each end of the chromosomes of most euka ...
, the enzyme that maintains the ends of
chromosomes A chromosome is a long DNA molecule with part or all of the genetic material of an organism. In most chromosomes the very long thin DNA fibers are coated with packaging proteins; in eukaryotic cells the most important of these proteins are ...
in
eukaryotic Eukaryotes () are organisms whose cells have a nucleus. All animals, plants, fungi, and many unicellular organisms, are Eukaryotes. They belong to the group of organisms Eukaryota or Eukarya, which is one of the three domains of life. Bacte ...
cells. *2002
Denis Le Bihan Denis Le Bihan (born July 30, 1957) is a Physician, medical doctor, physicist, member of the Institut de France (French Academy of Sciences, French Academy of sciences), member of the French Academy of Technologies and director since 2007 of NeuroS ...
, for his work on the invention and development of nuclear
magnetic resonance imaging Magnetic resonance imaging (MRI) is a medical imaging technique used in radiology to form pictures of the anatomy and the physiological processes of the body. MRI scanners use strong magnetic fields, magnetic field gradients, and radio wave ...
of brain diffusion and perfusion. The method he developed permits in vivo mapping of nerve fiber bundles and has multiple applications in both medical pathology and cognitive science fields. *2001
Elaine Fuchs Elaine V. Fuchs is an American cell biologist famous for her work on the biology and molecular mechanisms of mammalian skin and skin diseases, who helped lead the modernization of dermatology. Fuchs pioneered reverse genetics approaches, which ...
, for her fundamental insights into structure and function of
cytoskeletal The cytoskeleton is a complex, dynamic network of interlinking protein filaments present in the cytoplasm of all cells, including those of bacteria and archaea. In eukaryotes, it extends from the cell nucleus to the cell membrane and is compo ...
proteins and the relation of these proteins to human genetic diseases. *2000
Miroslav Radman Miroslav Radman (born April 30, 1944) is a Croatian biologist. Biography Radman was born in Split, PR Croatia, Yugoslavia. From 1962–1967 he studied experimental biology, physical chemistry and molecular biology at the University of Zagreb and ...
, for his contribution to the discovery of the molecular mechanisms implicated in the replication and repair of DNA, in particular, the discovery of a key enzyme of the DNA repair mechanism. *1999
Elliot M. Meyerowitz Elliot Meyerowitz (born May 22, 1951) is an American biologist. Career Meyerowitz did his undergraduate work at Columbia University (A.B. in biology, 1973), where he worked part-time in the laboratory of Cyrus Levinthal on combined microscopic a ...
, for his pioneering contributions to the molecular genetics of plant architecture, which have practical implications for agriculture. *1998
Pascale Cossart Pascale Cossart (born 21 March 1948) is a French bacteriologist who is affiliated with the Pasteur Institute of Paris. She is the foremost authority on ''Listeria monocytogenes'', a deadly and common food-borne pathogen responsible for encephal ...
, for her fundamental discoveries in microbiology dealing with mechanisms of bacterial entry and intracellular host motility. *1997 James E. Rothman, for his dissection of the biochemical mechanisms by which proteins are transferred from one cellular compartment to another and to the outside world. These mechanisms are important in neurotransmission, tissue biogenesis, and hormonal secretion. *1996 Daniel Louvard and
Jacques Pouysségur Jacques Pouysségur is a French engineer and researcher. He was born on November 10, 1943 in Toulouse, Haute-Garonne. He is a research director emeritus of the CNRS. He has conducted research at the Institute for Research on Cancer and Aging, Ni ...
, for their contributions to the study of the regulation of
cell division Cell division is the process by which a parent cell (biology), cell divides into two daughter cells. Cell division usually occurs as part of a larger cell cycle in which the cell grows and replicates its chromosome(s) before dividing. In eukar ...
and differentiation. *1995 Douglas A. Melton, for showing how cells and tissues differentiate during vertebrate development through studies on localized mRNAs in eggs and the genes that induce
mesoderm The mesoderm is the middle layer of the three germ layers that develops during gastrulation in the very early development of the embryo of most animals. The outer layer is the ectoderm, and the inner layer is the endoderm.Langman's Medical E ...
and neural tissue. *1994 Jean Louis Mandel, for his work in human genetics and in particular for his discovery of the mutation of
fragile X Fragile X syndrome (FXS) is a genetic disorder characterized by mild-to-moderate intellectual disability. The average IQ in males with FXS is under 55, while about two thirds of affected females are intellectually disabled. Physical features may ...
. This new type of mutation has now been found at the origin of the diseases. *1993 Stanley B. Prusiner and
Bert Vogelstein Bert Vogelstein (born 1949) is director of the Ludwig Center, Clayton Professor of Oncology and Pathology and a Howard Hughes Medical Institute investigator at The Johns Hopkins Medical School and Sidney Kimmel Comprehensive Cancer Center. A pi ...
, for their distinct and exciting discoveries about the pathogenesis of neurodegenerative and malignant diseases. This award is given as a celebration of the power of modern molecular medicine. *1992 Philippe Ascher and Henri Korn, for their discoveries of the mechanisms of synaptic transmission. Philippe Asher furthered knowledge regarding the properties of glutamate receptors which play an important role in trials, and Henri Korn brought to light the elementary liberation of neurotransmitter in quanta form in the
central nervous system The central nervous system (CNS) is the part of the nervous system consisting primarily of the brain and spinal cord. The CNS is so named because the brain integrates the received information and coordinates and influences the activity of all par ...
of vertebrates. *1991
Marc W. Kirschner Marc Wallace Kirschner (born February 28, 1945) is an Americans, American cell biologist and biochemist and the founding chair of the Department of Systems Biology at Harvard Medical School. He is known for major discoveries in cell and developmen ...
, for elucidating key steps in the cell cycle, chromosome movement, cell cycle timing, nucleus breakdown and reformation, and microtubule control of cell polarity and
mitosis In cell biology, mitosis () is a part of the cell cycle in which replicated chromosomes are separated into two new nuclei. Cell division by mitosis gives rise to genetically identical cells in which the total number of chromosomes is mainta ...
. *1991
Harold Weintraub Harold M. "Hal" Weintraub was an American scientist who lived from 1945 until his death in 1995 from an aggressive brain tumor. Only 49 years old, Weintraub left behind a legacy of research. Early life and education Born on June 2, 1945, in ...
, for elucidating a molecular mechanism by which a single regulatory gene can lead to a program of cell differentiation. *1990 Jean Rosa, for his contributions, which have opened a new road in the control of oxygen transport in the blood and the treatment of the first worldwide genetic plague,
drepanocytosis Sickle cell disease (SCD) is a group of blood disorders typically Heredity, inherited from a person's parents. The most common type is known as sickle cell anaemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found i ...
. *1989
Richard Axel Richard Axel (born July 2, 1946) is an American molecular biologist and university professor in the Department of Neuroscience at Columbia University and investigator at the Howard Hughes Medical Institute. His work on the olfactory system won hi ...
, for his discoveries elucidating gene structure in animal cells. *1988 François Cuzin, for his original contributions in the elucidation of the mechanisms involved in malignant cell transformation, in particular, demonstration of the necessary contribution of two oncogenes. *1987 Alfred G. Gilman and
Martin Rodbell Martin Rodbell (December 1, 1925 – December 7, 1998) was an American biochemist and molecular endocrinologist who is best known for his discovery of G-proteins. He shared the 1994 Nobel Prize in Physiology or Medicine with Alfred G. Gilman fo ...
, for their discoveries regarding the proteins and mechanisms that mediate cellular responses to the binding of ligands to cell surface receptors. *1986 André Capron and Jacques Glowinski, for their fundamental work, which has contributed to the treatment of parasitic and neurological diseases. *1985 Martin Gellert and
Thomas Maniatis Tom Maniatis (born May 8, 1943), is an American professor of molecular and cellular biology. He is a professor at Columbia University, and serves as the Scientific Director and CEO of the New York Genome Center. Education Maniatis received B.A ...
, for their seminal contributions to our understanding of the structure and function of DNA, which were essential and fundamental to the development of recombinant DNA techniques. *1984 Maxime Schwartz, for his genetic and biochemical analysis of the maltose system of
E.Coli ''Escherichia coli'' (),Wells, J. C. (2000) Longman Pronunciation Dictionary. Harlow ngland Pearson Education Ltd. also known as ''E. coli'' (), is a Gram-negative, facultative anaerobic, rod-shaped, coliform bacterium of the genus ''Esche ...
, which paved the way for the solution of a series of fundamental problems in molecular biology. *1983
Günter Blobel Günter Blobel (; May 21, 1936 – February 18, 2018) was a Silesian German and American biologist and 1999 Nobel Prize laureate in Physiology for the discovery that proteins have intrinsic signals that govern their transport and localization in ...
, for his work in uncovering the molecular interactions that control the traffic of newly synthesized proteins in eukaryotic cells, for his incisive experiments, and for the beauty of the findings by which he established these interactions. *1982
Pierre Chambon Pierre Chambon (born 7 February 1931 in Mulhouse, France) was the founder of the in Strasbourg, France. He was one of the leading molecular biologists who utilized gene cloning and sequencing technology to first decipher the structure of eukaryot ...
and Jean-Pierre Changeux, for their work on fundamental structures of genetic material and of the nervous system. *1981
Philip Leder Philip Leder (November 19, 1934 – February 2, 2020) was an American geneticist. Early life and education Leder was born in Washington, D.C. and studied at Harvard University, graduating in 1956. In 1960, he graduated from Harvard Medical Sc ...
, for his series of notable contributions in molecular genetics, which help to explain the means by which genetic information is organized and used to direct the synthesis of specific cell products. *1980 , for his work on the physiology of the
kidney The kidneys are two reddish-brown bean-shaped organs found in vertebrates. They are located on the left and right in the retroperitoneal space, and in adult humans are about in length. They receive blood from the paired renal arteries; blood ...
. *1979 Michael S. Brown and Joseph L. Goldstein, for their work in
cholesterol Cholesterol is any of a class of certain organic molecules called lipids. It is a sterol (or modified steroid), a type of lipid. Cholesterol is biosynthesized by all animal cells and is an essential structural component of animal cell mem ...
biosynthesis.


See also

*
List of biomedical science awards This list of biomedical science awards is an index to articles on notable awards for biomedical sciences, a set of sciences applying portions of natural science or formal science, or both, to knowledge, interventions, or technology that are of u ...


References


External links

* See als
Other NAS Awards


from the Richard Lounsbery Foundation {{National Academy of Sciences, state= collapsed Awards established in 1979 Biomedical awards French Academy of Sciences French awards Awards of the United States National Academy of Sciences 1979 establishments in France 1979 establishments in Washington, D.C. American science and technology awards France–United States relations