Naringenin chalcone
is a common
chalconoid
Chalconoids Greek: χαλκός ''khalkós'', "copper", due to its color), also known as ''chalcones'', are natural phenols related to chalcone. They form the central core for a variety of important biological compounds.
They show antibacterial, ...
(or chalcone, not to be confused with the compound
chalcone
Chalcone is the organic compound C6H5C(O)CH=CHC6H5. It is an α,β-unsaturated ketone. A variety of important biological compounds are known collectively as chalcones or chalconoids.
Chemical properties
Chalcones have two absorption maxima a ...
). It is synthesized from
4-coumaroyl-CoA
Coumaroyl-coenzyme A is the thioester of coenzyme-A and coumaric acid. Coumaroyl-coenzyme A is a central intermediate in the biosynthesis of myriad natural products found in plants. These products include Monolignol, lignols (precursors to lignin ...
and
malonyl-CoA
Malonyl-CoA is a coenzyme A derivative of malonic acid.
Functions
It plays a key role in chain elongation in fatty acid biosynthesis and polyketide biosynthesis.
Fatty acid biosynthesis
Malonyl-CoA provides 2-carbon units to fatty acids and commi ...
by
chalcone synthase (CHS), a key enzyme in the
phenylpropanoid pathway. Naringenin chalcone can spontaneously
cyclize to
naringenin (a
flavanone). In plant cells, this process is catalyzed by
chalcone isomerase.
References
Chalconoids
{{organic-compound-stub