David Gardner-Medwin
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David Gardner-Medwin (13 November 193614 June 2014) was a British physician who worked as a paediatric neurologist in
Newcastle upon Tyne Newcastle upon Tyne ( RP: , ), or simply Newcastle, is a city and metropolitan borough in Tyne and Wear, England. The city is located on the River Tyne's northern bank and forms the largest part of the Tyneside built-up area. Newcastle is ...
, serving as the only neurologist for children for a population of 3.5 million. He is credited with introducing multidisciplinary care to the management of boys with Duchenne muscular dystrophy (DMD). When he retired at the age of 60, four consultants were appointed to replace him. In the 1960s, working as a research fellow with neurologist John Walton, he studied the genetics and clinical features of the diseases of muscles, particularly relating to the identification of female carriers of DMD. Parallel to his career in medicine was his interest in natural history and involvement with the Natural History Society of Northumbria, the binding and restoration of books and studies on Thomas Bewick. He finished a study of Bewick's family history and contributed to the Bewick Birthplace Trust's campaign to preserve Bewick's birthplace of Cherryburn in Northumberland.


Early life and education

David Gardner-Medwin was born on 13 November 1936 at
The London Clinic The London Clinic is a private healthcare organisation and registered charity based on the corner of Devonshire Place and Marylebone Road in central London. According to HealthInvestor, it is one of England's largest private hospitals. Histor ...
in
Marylebone Marylebone (usually , also , ) is a district in the West End of London, in the City of Westminster. Oxford Street, Europe's busiest shopping street, forms its southern boundary. An Civil parish#Ancient parishes, ancient parish and latterly a ...
, to Robert Joseph Gardner-Medwin, a British architect, and Margaret Gardner-Medwin née Kilgour, a Canadian. The eldest of four sons, he spent his childhood first in London, followed by evacuation to Canada during the
Second World War World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposin ...
. Before the end of the war his family moved to Barbados where his father took up a job in development and planning, and later they transferred to
Edinburgh Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian ...
, where he was educated at the Edinburgh Academy, and where he became interested in
ornithology Ornithology is a branch of zoology that concerns the "methodological study and consequent knowledge of birds with all that relates to them." Several aspects of ornithology differ from related disciplines, due partly to the high visibility and th ...
.Holmes, June (2014
"Dr David Gardner-Medwin (1936–2014)"
Natural History Society of Northumbria
Tribute to David Gardner‐Medwin
Janet Gardner‐Medwin 27 June 2014
He gained admission to study
natural sciences Natural science is one of the branches of science concerned with the description, understanding and prediction of natural phenomena, based on empirical evidence from observation and experimentation. Mechanisms such as peer review and repeatab ...
at
King's College King's College or The King's College refers to two higher education institutions in the United Kingdom: *King's College, Cambridge, a constituent of the University of Cambridge *King's College London, a constituent of the University of London It ca ...
, University of Cambridge, but shortly after starting, switched to medicine. There, he produced his first publication on the migration of birds across the
Pyrenees The Pyrenees (; es, Pirineos ; french: Pyrénées ; ca, Pirineu ; eu, Pirinioak ; oc, Pirenèus ; an, Pirineus) is a mountain range straddling the border of France and Spain. It extends nearly from its union with the Cantabrian Mountains to C ...
. After being gifted the first edition of a '' A History of British Birds'' by his grandmother on his twentieth birthday, he became interested in the naturalist and wood engraver Thomas Bewick. He completed his clinical training at St Bartholomew's Hospital, and graduated in 1962.


Career

Gardner-Medwin completed his junior posts at Exeter and Farnborough, before taking up a job in
pathology Pathology is the study of the causes and effects of disease or injury. The word ''pathology'' also refers to the study of disease in general, incorporating a wide range of biology research fields and medical practices. However, when used in ...
at St Bartholomew's. Subsequently, he worked under neurologist John Aldren Turner before moving to Newcastle to take up the post of Medical Research Council research fellow to John Walton, later Lord Walton of Detchant, with whom he studied the genetics and clinical features of
muscular dystrophies Muscular dystrophies (MD) are a genetically and clinically heterogeneous group of rare neuromuscular diseases that cause progressive weakness and breakdown of skeletal muscles over time. The disorders differ as to which muscles are primarily affe ...
, particularly relating to the identification of female carriers of the X-linked recessive gene responsible for the most severe form of the disease, Duchenne muscular dystrophy (DMD). By measuring the muscle enzyme creatinine kinase in blood samples, and taking into account various indicators such as other genetic markers and family history, he worked out the likelihood that a woman might be carrying the gene for DMD. It became the subject of a thesis for which he gained an MD in 1972. After spending some time in adult neurology, paediatrics and child psychiatry, he was awarded a neurology fellowship in Boston, working with
Raymond Adams Raymond is a male given name. It was borrowed into English from French (older French spellings were Reimund and Raimund, whereas the modern English and French spellings are identical). It originated as the Germanic ᚱᚨᚷᛁᚾᛗᚢᚾᛞ ( ...
at the
Massachusetts General Hospital Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United Stat ...
and Charles Barlow at Boston Children's Hospital. In 1971 he returned to Newcastle and the following year was appointed the first consultant paediatric neurologist to the northern region, where for many years, he served as the only neurologist for children for a population of 3.5 million. To his colleagues he became known as DGM and is credited with introducing multidisciplinary care and nocturnal ventilation to the management of boys with DMD. During his career at Newcastle, the chances of survival for children with DMD improved from 0% to reaching age 25 years in the 1960s to 12% in the 1980s, and 53% after 1990. Despite the initial classification of limb–girdle muscular dystrophy by Walton in the 1950s, both Walton and Gardner-Medwin challenged the term by 1994, describing that some of the features in this group of muscle disorders disguised other conditions, and they "recognize that research in this long neglected group of muscular dystrophies is still in an early and transitional stage". When he retired at the age of 60, four consultants were appointed to replace him.


Later life

In 1997 he attended the public enquiry on the expansion of military use of the Otterburn Moors in the Cheviot Hills, and his comments led to mitigation of the impact of the army's manoeuvres upon wildlife in
Northumberland Northumberland () is a county in Northern England, one of two counties in England which border with Scotland. Notable landmarks in the county include Alnwick Castle, Bamburgh Castle, Hadrian's Wall and Hexham Abbey. It is bordered by land on ...
. He co-founded the
British Paediatric Neurology Association British may refer to: Peoples, culture, and language * British people, nationals or natives of the United Kingdom, British Overseas Territories, and Crown Dependencies. ** Britishness, the British identity and common culture * British English, ...
and later became its secretary and treasurer. He then became secretary of the Mac Keith Press, which publishes work on neurological conditions of children.


Natural history

Parallel to his career in medicine was his interest in natural history and in the binding and restoration of books. In 1966 he became involved with the Natural History Society of Northumbria, for which he was once chairman of its library committee and later chairman of its council. He also became president of the Friends of the
Newcastle University Library Newcastle University Library is the library service for students and staff at Newcastle University, UK. It consists of: * The Philip Robinson Library, the main library, offers collections in arts, humanities, social sciences, science and engine ...
. He finished a study of Bewick's family history and contributed to the Bewick Birthplace Trust's campaign to preserve Cherryburn and promote Bewick's works, and he later became vice president of the Thomas Bewick Society.


Personal and family

He met Alisoun Shire when he was at Cambridge and they married in the chapel of King's College. They had two children, including Janet who became a paediatrician. Gardner-Medwin died from leukaemia on 14 June 2014, at the age of 77.


Selected publications

* * *Gardner-Medwin, David (May 1980)
"Clinical features and classification of the muscular dystrophies"
''
British Medical Bulletin ''British Medical Bulletin'' is a quarterly peer-reviewed general medical journal that publishes review articles on a wide variety of medical subjects. The journal was established in 1943 and is published by Oxford University Press. The editor-in- ...
'', Volume 36, Issue 2, May 1980, Pages 109–116, *


References


External links

* {{DEFAULTSORT:Gardner-Medwin, David 1936 births 2014 deaths British neurologists People from Marylebone English bibliophiles 20th-century English medical doctors English ornithologists Muscular dystrophy Deaths from leukemia