This is a list of

corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involv ...

cyclic Cycle, cycles, or cyclic may refer to: Anthropology and social sciences * Cyclic history, a theory of history * Cyclical theory, a theory of American political history associated with Arthur Schlesinger, Sr. * Social cycle, various cycles in s ...

ketal In organic chemistry, an acetal is a functional group with the connectivity . Here, the R groups can be organic fragments (a carbon atom, with arbitrary other atoms attached to that) or hydrogen, while the R' groups must be organic fragments no ...

s, including cyclic ketals (cyclic

acetal In organic chemistry, an acetal is a functional group with the connectivity . Here, the R groups can be organic fragments (a carbon atom, with arbitrary other atoms attached to that) or hydrogen, while the R' groups must be organic fragments no ...

s) of

steroid A steroid is a biologically active organic compound with four rings arranged in a specific molecular configuration. Steroids have two principal biological functions: as important components of cell membranes that alter membrane fluidity; and a ...

glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every vertebr ...

s and

mineralocorticoid Mineralocorticoids are a class of corticosteroids, which in turn are a class of steroid hormones. Mineralocorticoids are produced in the adrenal cortex and influence salt and water balances (electrolyte balance and fluid balance). The primary mi ...

s. They are almost all C16α,17α cyclic ketals of corticosteroids. One of the most widely used corticosteroid cyclic ketals is

triamcinolone acetonide Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat ...

, which is the C16α,17α

acetonide In organic chemistry, an acetonide is the functional group composed of the cyclic ketal of a diol with acetone. The more systematic name for this structure is an isopropylidene ketal. Acetonide is a common protecting group for 1,2- and 1,3- diol ...

(cyclic ketone with

acetone Acetone (2-propanone or dimethyl ketone), is an organic compound with the formula . It is the simplest and smallest ketone (). It is a colorless, highly volatile and flammable liquid with a characteristic pungent odour. Acetone is miscib ...

) of

triamcinolone Triamcinolone is a glucocorticoid used to treat certain skin diseases, allergies, and rheumatic disorders among others. It is also used to prevent worsening of asthma and COPD. It can be taken in various ways including by mouth, injection into ...

. This list mostly does not include esters of corticosteroid cyclic ketals, which are listed

here Here is an adverb that means "in, on, or at this place". It may also refer to: Software * Here Technologies, a mapping company * Here WeGo (formerly Here Maps), a mobile app and map website by Here Television * Here TV (formerly "here!"), a TV ...

instead.

Acetonides

Acetonide In organic chemistry, an acetonide is the functional group composed of the cyclic ketal of a diol with acetone. The more systematic name for this structure is an isopropylidene ketal. Acetonide is a common protecting group for 1,2- and 1,3- diol ...

s (cyclic ketals with

): * Cicortonide *

Ciprocinonide Ciprocinonide (developmental code name RS-2386), also known as fluocinolone acetonide cyclopropylcarboxylate, is a synthetic glucocorticoid corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cort ...

(fluocinolone acetonide cyclopropylcarboxylate) *

Descinolone acetonide Descinolone acetonide (developmental code name CL-27071), also known as desoxytriamcinolone acetonide, is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class ...

(desoxytriamcinolone acetonide) *

Desonide Desonide (INN) is a low-potency topical corticosteroid anti-inflammatory that has been available since the 1970s. It is primarily used to treat atopic dermatitis (eczema), seborrheic dermatitis, contact dermatitis and psoriasis Psoriasis is ...

(desfluorotriamcinolone acetonide) * Drocinonide *

Fluclorolone acetonide Fluclorolone acetonide (INN, or flucloronide, USAN 280px, "Samguk Sagi" Book 04. Silla's Records. In 512, Usan-guk（于山國）was Ulleungdo（鬱陵島） Usan-guk, or the State of Usan, occupied Ulleung-do and the adjacent islands dur ...

(flucloronide) * Fludroxycortide (flurandrenolide, flurandrenolone) * Flumoxonide *

Flunisolide Flunisolide (marketed as AeroBid among others) is a corticosteroid often prescribed as treatment for allergic rhinitis. Intranasal corticosteroids are the most effective medication for controlling symptoms. The principal mechanism of action of ...

Fluocinolone acetonide Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances ...

Fluocinonide Fluocinonide (sold under various brand names) is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. It relieves itching, redness, dryness, crusti ...

(fluocinolone acetonide 21-acetate) *

Flupamesone Flupamesone (brand name Flutenal), also known as triamcinolone acetonide metembonate, is a synthetic compound, synthetic glucocorticoid corticosteroid which is marketed in Spain. It is a dimer (chemistry), dimer of a C21 ester of triamcinolone ac ...

(triamcinolone acetonide metembonate) *

Formocortal Formocortal (INN), also known as fluoroformylone, is a corticosteroid used in dermatology and ophthalmology. It was introduced in around 1970 and is not known to be marketed . See also * Glucocorticoid Glucocorticoids (or, less commonly, ...

Halcinonide Halcinonide is a high potency corticosteroid, in group II (second most potent group) under US classification. It is used topical A topical medication is a medication that is applied to a particular place on or in the body. Most often topic ...

Procinonide Procinonide (developmental code RS-2362; also known as fluocinolone acetonide propionate) is a synthetic glucocorticoid corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, ...

(fluocinolone acetonide propionate) *

Tralonide Tralonide (brand name Talidan) is a synthetic compound, synthetic glucocorticoid corticosteroid. References

Acetonides Chloroarenes Corticosteroid cyclic ketals Diketones Fluoroarenes Glucocorticoids Pregnanes {{steroid-stub ...

Triamcinolone acetonide Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat ...

Triamcinolone benetonide Triamcinolone benetonide (brand names Alcorten, Benecorten, Tibicorten; also known as triamcinolone acetonide 21-(benzoyl-β-aminoisobutyrate) or TBI) is a synthetic compound, synthetic glucocorticoid corticosteroid. References

Acetoni ...

(triamcinolone acetonide 21-(benzoyl-β-aminoisobutyrate)) *

Triamcinolone furetonide Triamcinolone furetonide (developmental code name HE-192; also known as triamcinolone acetonide 21-(2-benzofurancarboxylate)) is a synthetic glucocorticoid corticosteroid Corticosteroids are a class of steroid hormones that are produced in th ...

(triamcinolone acetonide 21-(2-benzofurancarboxylate)) *

Triamcinolone hexacetonide Triamcinolone hexacetonide (brand name Aristospan; also known as triamcinolone acetonide 21-tebutate) is a synthetic glucocorticoid corticosteroid. It is on the World Health Organization's List of Essential Medicines The WHO Model List o ...

(triamcinolone acetonide 21-tebutate) *

Triclonide Triclonide (developmental code name RS-4464) is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids t ...

Others

Acetophenides

Acetophenide In organic chemistry, acetophenide is a functional group which is composed of the cyclic ketal of a diol with acetophenone. In pharmaceutical chemistry, it is present in algestone acetophenide (dihydroxyprogesterone acetophenide) and amcinafide ( ...

s (cyclic ketals with

acetophenone Acetophenone is the organic compound with the formula C6H5C(O)CH3. It is the simplest aromatic ketone. This colorless, viscous liquid is a precursor to useful resins and fragrances. Production Acetophenone is formed as a byproduct of the cumene p ...

): *

Algestone acetophenide Algestone acetophenide, also known more commonly as dihydroxyprogesterone acetophenide (DHPA) and sold under the brand names Perlutal and Topasel among others, is a progestin medication which is used in combination with an estrogen as a form of ...

(dihydroxyprogesterone acetophenide) *

Amcinafide Amcinafide (developmental code name SQ-15112), also known as triamcinolone acetophenide, is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hor ...

(triamcinolone acetophenide)

Acroleinides

Acroleinide In organic chemistry, acroleinide is a functional group which is composed of a cyclic ketal of a diol with acrolein. In pharmaceutical chemistry, it is present in acrocinonide (triamcinolone acroleinide). See also * Acetonide * Acetophenide * ...

s (cyclic ketals with

acrolein Acrolein (systematic name: propenal) is the simplest unsaturated aldehyde. It is a colorless liquid with a piercing, acrid smell. The smell of burnt fat (as when cooking oil is heated to its smoke point) is caused by glycerol in the burning fa ...

): *

Acrocinonide Acrocinonide (developmental code name SD 2102-18; also known as triamcinolone acroleinide) is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid h ...

(triamcinolone acroleinide)

Aminobenzals

Aminobenzal In organic chemistry, aminobenzal is a functional group which is composed of a cyclic ketal of a diol with 4-dimethylaminobenzylidene. It is seen in triamcinolone aminobenzal benzamidoisobutyrate. See also * Acetonide * Acetophenide * Acroleinide ...

s (cyclic ketals with 4-dimethylaminobenzylidene): *

Triamcinolone aminobenzal benzamidoisobutyrate Triamcinolone aminobenzal benzamidoisobutyrate (TBI-PAB; brand name Taucorten) is a synthetic compound, synthetic glucocorticoid corticosteroid which is no longer marketed. References

Secondary alcohols Benzamides Aminobenzals Corticos ...

(TBI-PAB)

Cyclopentanonides

Cyclopentanonide In organic chemistry, cyclopentanonide is a functional group which is composed of a cyclic ketal of a diol with cyclopentanone. It is seen in amcinonide (triamcinolone acetate cyclopentanonide). See also * Acetonide * Acetophenide * Acroleinide * ...

s (cyclic ketals with

cyclopentanone Cyclopentanone is the organic compound with the formula (CH2)4CO. This cyclic ketone is a colorless volatile liquid. Preparation Upon treatment with barium hydroxide at elevated temperatures, adipic acid undergoes ketonization to give cyclopenta ...

): *

Amcinonide Amcinonide (trade name Cyclocort) is a topical glucocorticoid used to treat itching, redness and swelling associated with several dermatologic conditions such as atopic dermatitis and allergic contact dermatitis. Amcinonide can also be classifi ...

(triamcinolone acetate cyclopentanonide)

Pentanonides

Pentanonide In organic chemistry, pentanonide is a functional group which is composed of a cyclic ketal of a diol with 3-pentanone. It is seen in amcinafal (triamcinolone pentanonide). See also * Acetonide In organic chemistry, an acetonide is the functio ...

s (cyclic ketals with 3-pentanone) *

Amcinafal Amcinafal (developmental code name SQ-15102), also known as triamcinolone pentanonide, is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormo ...

(triamcinolone pentanonide)

With butyraldehyde

Cyclic ketals with

butyraldehyde Butyraldehyde, also known as butanal, is an organic compound with the formula CH3(CH2)2CHO. This compound is the aldehyde derivative of butane. It is a colorless flammable liquid with an unpleasant smell. It is miscible with most organic solvents. ...

: *

Budesonide Budesonide, sold under the brand name Pulmicort among others, is a medication of the corticosteroid type. It is available as an inhaler, nebulization solution, pill, nasal spray, and rectal forms. The inhaled form is used in the long-term mana ...

* Dexbudesonide * Itrocinonide * Rofleponide

Miscellaneous

* Nicocortonide is a C14α,17α cyclic ketal with

crotonaldehyde Crotonaldehyde is a chemical compound with the formula CH3CH=CHCHO. The compound is usually sold as a mixture of the ''E''- and ''Z''-isomers, which differ with respect to the relative position of the methyl and formyl groups. The ''E''-isomer ...

References

{{Mineralocorticoid receptor modulators Corticosteroid cyclic ketals Corticosteroids Glucocorticoids