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Corticosteroid Cyclic Ketals
This is a list of corticosteroid cyclic ketals, including cyclic ketals (cyclic acetals) of steroidal glucocorticoids and mineralocorticoids. They are almost all C16α,17α cyclic ketals of corticosteroids. One of the most widely used corticosteroid cyclic ketals is triamcinolone acetonide, which is the C16α,17α acetonide (cyclic ketone with acetone) of triamcinolone. This list mostly does not include esters of corticosteroid cyclic ketals, which are listed here instead. Acetonides Acetonides (cyclic ketals with acetone): * Cicortonide * Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate) * Descinolone acetonide (desoxytriamcinolone acetonide) * Desonide (desfluorotriamcinolone acetonide) * Drocinonide * Fluclorolone acetonide (flucloronide) * Fludroxycortide (flurandrenolide, flurandrenolone) * Flumoxonide * Flunisolide * Fluocinolone acetonide * Fluocinonide (fluocinolone acetonide 21-acetate) * Flupamesone (triamcinolone acetonide metembonate) * Formocortal * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triamcinolone Acetonide
Triamcinolone acetonide, sold under the brand name Kenalog among others, is a synthetic corticosteroid medication used topically to treat various skin conditions, to relieve the discomfort of mouth sores, and by injection into joints to treat various joint conditions. It is also injected into lesions to treat inflammation in some parts of the body, particularly the skin. In nasal spray form, it is used to treat allergic rhinitis. It is used for the treatment of macular edema associated with uveitis. It is a more potent derivative of triamcinolone, and is about eight times as potent as prednisone. Most forms of triamcinolone acetonide are Prescription drug, prescription drugs. In 2014, the U.S. Food and Drug Administration (FDA) made triamcinolone acetonide an over-the-counter drug in the United States in nasal spray form under the brand name Nasacort. Medical uses Triamcinolone acetonide as an intra-articular injectable has been used to treat a variety of musculoskeletal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Descinolone Acetonide
Descinolone acetonide (developmental code name CL-27071), also known as desoxytriamcinolone acetonide, is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every verteb ... corticosteroid which was never marketed. References Acetonides Cyclohexanols Corticosteroid cyclic ketals Diketones Fluoroarenes Glucocorticoids Pregnanes Enones {{steroid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tralonide
Tralonide (brand name Talidan) is a synthetic compound, synthetic glucocorticoid corticosteroid. References Acetonides Chloroarenes Corticosteroid cyclic ketals Diketones Fluoroarenes Glucocorticoids Pregnanes {{steroid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Procinonide
Procinonide (developmental code RS-2362; also known as fluocinolone acetonide propionate) is a synthetic glucocorticoid corticosteroid Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are inv ... which was never marketed. References Acetonides Secondary alcohols Corticosteroid cyclic ketals Corticosteroid esters Organofluorides Glucocorticoids Pregnanes Propionate esters Diketones Abandoned drugs {{steroid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Halcinonide
Halcinonide is a high potency corticosteroid, in group II (second most potent group) under US classification. It is used topical A topical medication is a medication that is applied to a particular place on or in the body. Most often topical medication means application to body surfaces such as the skin or mucous membranes to treat ailments via a large range of classes ...ly (in a 0.05% cream provided as Halog) in the treatment of certain skin conditions. References Acetonides Secondary alcohols Chloroarenes Corticosteroid cyclic ketals Corticosteroids Diketones Fluoroarenes Glucocorticoids {{dermatologic-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Formocortal
Formocortal (INN), also known as fluoroformylone, is a corticosteroid used in dermatology and ophthalmology. It was introduced in around 1970 and is not known to be marketed . See also * Glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every verteb ... References Acetate esters Acetonides Secondary alcohols Chloroarenes Corticosteroid cyclic ketals Corticosteroids Corticosteroid esters Fluoroarenes Glucocorticoids {{dermatologic-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flupamesone
Flupamesone (brand name Flutenal), also known as triamcinolone acetonide metembonate, is a synthetic compound, synthetic glucocorticoid corticosteroid which is marketed in Spain. It is a dimer (chemistry), dimer of a C21 ester of triamcinolone acetonide. References Acetonides Corticosteroid cyclic ketals Corticosteroid esters Dimers (chemistry) Diols Fluoroarenes Glucocorticoids Naphthalenes Polyketones Pregnanes {{steroid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluocinonide
Fluocinonide (sold under various brand names) is a potent glucocorticoid used topically as an anti-inflammatory agent for the treatment of skin disorders such as eczema and seborrhoeic dermatitis. It relieves itching, redness, dryness, crusting, scaling, inflammation, and discomfort. A common potential adverse effect is skin atrophy (thinning of the skin). Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal axis (HPA) suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria Glycosuria is the excretion of glucose into the urine. Ordinarily, urine contains no glucose because the kidneys are able to reabsorb all of the filtered glucose from the tubular fluid back into the bloodstream. Glycosuria is nearly always caused .... In 2020, it was the 280th most commonly prescribed medication in the United States, with more than 1million prescriptions. Veterinary uses Fluocinonide is used in veterinary medic ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluocinolone Acetonide
Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. It was first synthesized in 1959 in the Research Department of Syntex Laboratories S.A. Mexico City. Preparations containing it were first marketed under the name Synalar. A typical dosage strength used in dermatology is 0.01–0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin. Fluocinolone acetonide was also found to strongly potentiate TGF-β-associated chondrogenesis of bone marrow mesenchymal stem/progenitor cells, by increasing the levels of collagen type II by more than 100 fold compared to the widely used dexamethasone. Fluocinolone acetonide intravitreal implants have been used to treat non-infectious uveitis. A systematic review could not determine whether fluocinolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flunisolide
Flunisolide (marketed as AeroBid among others) is a corticosteroid often prescribed as treatment for allergic rhinitis. Intranasal corticosteroids are the most effective medication for controlling symptoms. The principal mechanism of action of flunisolide is to activate glucocorticoid receptors, meaning it has an anti-inflammatory action. The effects of topical corticosteroids is not immediate and requires regular use and at least a few days to start experiencing noticeable symptom relief. As-needed use has been shown to be not as effective as regular recommended use. Flunisolide should not be used in the presence of nasal infection. It should not be continued if there is no relief of symptoms after regular use over two to three weeks. It was patented in 1958 and approved for medical use in 1978. It is on the World Health Organization's List of Essential Medicines. Side effects Temporary nose and throat dryness, irritation, bleeding or unpleasant taste or smell may occur. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flumoxonide
Flumoxonide (developmental code name RS-40584) is a synthetic glucocorticoid Glucocorticoids (or, less commonly, glucocorticosteroids) are a class of corticosteroids, which are a class of steroid hormones. Glucocorticoids are corticosteroids that bind to the glucocorticoid receptor that is present in almost every verteb ... corticosteroid which was never marketed. References Acetonides Cyclohexanols Corticosteroid cyclic ketals Diketones Fluoroarenes Glucocorticoids {{steroid-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fludroxycortide
Fludroxycortide (INN, BAN, JAN), also known as flurandrenolide (USAN) and flurandrenolone, is a synthetic topical corticosteroid and is used as an anti-inflammatory treatment for use on skin irritations. Trade names include Haelan (Typharm, UK) and Cordran (by Watson Pharmaceuticals, US). Fludroxycortide is available in ointment, cream and as an impregnated tape (Haelan tape, Cordran tape). Licensed indications in the United Kingdom include recalcitrant dermatoses A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s .... References Acetonides Primary alcohols Cyclohexanols Corticosteroid cyclic ketals Corticosteroids Diketones Fluoroarenes Glucocorticoids Pregnanes {{dermatologic-drug-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |