City of Hope is a private, not-for-profit clinical research center,

hospital A hospital is a health care institution providing patient treatment with specialized health science and auxiliary healthcare staff and medical equipment. The best-known type of hospital is the general hospital, which typically has an emerge ...

and

graduate school Postgraduate or graduate education refers to Academic degree, academic or professional degrees, certificates, diplomas, or other qualifications pursued by higher education, post-secondary students who have earned an Undergraduate education, un ...

located in

Duarte, California Duarte () is a city in Los Angeles County, California, United States. As of the 2020 census, the city population was 21,727. It is bounded to the north by the San Gabriel Mountains, to the north and west by the cities of Bradbury and Monrovia ...

, United States. The center's main campus resides on of land adjacent to the boundaries of Duarte and

Irwindale Irwindale is a city in the San Gabriel Valley, in Los Angeles County, California. The population was 1,422 at the 2010 census, down from 1,446 at the 2000 census. The ZIP Codes serving the area are 91010, which is shared with Duarte, 91702, w ...

, with a network of clinical practice locations throughout Southern California, satellite offices in

Monrovia Monrovia () is the capital city of the West African country of Liberia. Founded in 1822, it is located on Cape Mesurado on the Atlantic coast and as of the 2008 census had 1,010,970 residents, home to 29% of Liberia’s total population. As the ...

and Irwindale, and regional fundraising offices throughout the United States. City of Hope is best known as a

cancer treatment Cancer can be treated by surgery, chemotherapy, radiation therapy, hormonal therapy, targeted therapy (including immunotherapy such as monoclonal antibody therapy) and synthetic lethality, most commonly as a series of separate treatments (e.g. ...

center. It has been designated a

Comprehensive Cancer Center NCI-designated Cancer Centers are a group of 71 cancer research institutions in the United States supported by the National Cancer Institute. Program Three designations are recognized: Comprehensive Cancer Centers, Clinical Cancer Centers, and Ba ...

by the

National Cancer Institute The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. ...

. City of Hope has also been ranked one of the nation's Best Cancer Hospitals by ''U.S. News & World Report'' for over ten years and is a founding member of the

National Comprehensive Cancer Network National Comprehensive Cancer Network (NCCN) is an alliance of 32 cancer centers in the United States, most of which are designated by the National Cancer Institute (one of the U.S. National Institutes of Health) as comprehensive cancer centers. It ...

. City of Hope played a role in the development of synthetic human insulin in 1978. The center has performed 13,000 hematopoietic stem cell transplants as of 2016 with patient outcomes that consistently exceed national averages.

History

In the late 19th and early 20th centuries, the spread of

tuberculosis Tuberculosis (TB) is an infectious disease usually caused by '' Mycobacterium tuberculosis'' (MTB) bacteria. Tuberculosis generally affects the lungs, but it can also affect other parts of the body. Most infections show no symptoms, in ...

, also known as "consumption", was a growing concern in the United States and Europe. Owing to advancements in the scientific understanding of its contagious nature, a

movement Movement may refer to: Common uses * Movement (clockwork), the internal mechanism of a timepiece * Motion, commonly referred to as movement Arts, entertainment, and media Literature * "Movement" (short story), a short story by Nancy Fu ...

to house and quarantine sufferers became prevalent. Construction of

tuberculosis sanatoria A sanatorium (from Latin '' sānāre'' 'to heal, make healthy'), also sanitarium or sanitorium, are antiquated names for specialised hospitals, for the treatment of specific diseases, related ailments and convalescence. Sanatoriums are often ...

, including tent cities, became common in the United States, with many sanatoriums located in the

Southwestern United States The Southwestern United States, also known as the American Southwest or simply the Southwest, is a geographic and cultural region of the United States that generally includes Arizona, New Mexico, and adjacent portions of California, Colorado, Ne ...

, where it was believed that the more arid climate would aid sufferers. In 1913, the ''Jewish Consumptive Relief Association'' was chartered in Los Angeles, California, with the intent of raising money to establish a free, non-sectarian

sanatorium A sanatorium (from Latin '' sānāre'' 'to heal, make healthy'), also sanitarium or sanitorium, are antiquated names for specialised hospitals, for the treatment of specific diseases, related ailments and convalescence. Sanatoriums are often ...

for persons from throughout the United States diagnosed with tuberculosis. After raising sufficient funds, the association purchased of land in Duarte, California, a small town in the more arid

San Gabriel Valley The San Gabriel Valley ( es, Valle de San Gabriel) is one of the principal valleys of Southern California, lying immediately to the east of the eastern city limits of the city of Los Angeles, and occupying the vast majority of the eastern part ...

, approximately east of downtown Los Angeles, and dubbed the property the Los Angeles Sanatorium. Opening January 11, 1914, the sanatorium originally consisted of two tents, one for patients and one for caregivers. The sanatorium was nicknamed "the city of hope", and grew in size for several decades, continuing to raise funds, construct permanent facilities, hire doctors and treat increasing numbers of patients. Treating tuberculosis remained the sanatorium's focus until after World War II, when

antibiotics An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention o ...

for tuberculosis were discovered. With tuberculosis becoming less prevalent, executive sanatorium director Samuel H. Golter began an initiative in 1946 to transform the sanatorium into a full medical center, supported by a research institute and post-graduate education. The Los Angeles Sanatorium officially changed its name to City of Hope National Medical Center in 1949. City of Hope's research institute was formally established in 1952. The City of Hope Graduate School of Biological Sciences was eventually chartered in 1993, and changed its name to the Irell & Manella Graduate School of Biological Sciences in 2009. From 1953 to 1985, under executive director Ben Horowitz, City of Hope grew further in size and became best known for its cancer research and treatment programs. Horowitz raised City of Hope's annual average operating budget from $600,000 to more than $100 million during his tenure. In 1981, the National Cancer Institute designated City of Hope a "Clinical Cancer Research Center". In 1983, the

Arnold and Mabel Beckman Foundation Arnold Orville Beckman (April 10, 1900 – May 18, 2004) was an American chemist, inventor, investor, and philanthropist. While a professor at California Institute of Technology, he founded Beckman Instruments based on his 1934 invention of th ...

awarded City of Hope a $10 million grant to establish the Beckman Research Institute of City of Hope; the Beckman Research Institute of City of Hope is now City of Hope's research moniker, and is one of six institutes/centers established by the Beckman Foundation in the United States. From 1983 to the present, City of Hope continued to grow, expanding its Duarte campus with additional patient care, research and support facilities. City of Hope also operates a network of community practice clinics throughout Southern California.

Research and treatment

City of Hope's institutional goals are the

prevention Prevention may refer to: Health and medicine * Preventive healthcare, measures to prevent diseases or injuries rather than curing them or treating their symptoms General safety * Crime prevention, the attempt to reduce deter crime and crimi ...

, treatment and

cure A cure is a substance or procedure that ends a medical condition, such as a medication, a surgical operation, a change in lifestyle or even a philosophical mindset that helps end a person's sufferings; or the state of being healed, or cured. The ...

of cancer and other life-threatening diseases, including

diabetes Diabetes, also known as diabetes mellitus, is a group of metabolic disorders characterized by a high blood sugar level ( hyperglycemia) over a prolonged period of time. Symptoms often include frequent urination, increased thirst and increased ap ...

and

HIV/AIDS Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual ...

. As such, City of Hope's programs include the fields of

brain A brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It is located in the head, usually close to the sensory organs for senses such as vision. It is the most complex organ in a v ...

breast The breast is one of two prominences located on the upper ventral region of a primate's torso. Both females and males develop breasts from the same embryological tissues. In females, it serves as the mammary gland, which produces and secret ...

gastrointestinal The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans and ...

gynecologic Gynaecology or gynecology (see spelling differences) is the area of medicine that involves the treatment of women's diseases, especially those of the reproductive organs. It is often paired with the field of obstetrics, forming the combined are ...

thoracic The thorax or chest is a part of the anatomy of humans, mammals, and other tetrapod animals located between the neck and the abdomen. In insects, crustaceans, and the extinct trilobites, the thorax is one of the three main divisions of the crea ...

and

urologic Urology (from Ancient Greek, Greek wikt:οὖρον, οὖρον ''ouron'' "urine" and ''wiktionary:-logia, -logia'' "study of"), also known as genitourinary surgery, is the branch of medicine that focuses on surgical and medical diseases of t ...

cancers, as well as

leukemia Leukemia ( also spelled leukaemia and pronounced ) is a group of blood cancers that usually begin in the bone marrow and result in high numbers of abnormal blood cells. These blood cells are not fully developed and are called ''blasts'' or ' ...

lymphoma Lymphoma is a group of blood and lymph tumors that develop from lymphocytes (a type of white blood cell). In current usage the name usually refers to just the cancerous versions rather than all such tumours. Signs and symptoms may include enlar ...

, and diabetes. City of Hope has been designated a

by the National Cancer Institute, a branch of the

National Institutes of Health The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late ...

. City of Hope is a

bench to bedside Translational medicine (often called translational science, of which it is a form) is defined by the European Society for Translational Medicine as "an interdisciplinary branch of the biomedical field supported by three main pillars: benchside, beds ...

institution, with investments in basic, translational and clinical research. Faculty, residents and fellows conduct

biomedical research Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientif ...

, treat patients and educate medical professionals with the medical center serving as a

teaching hospital A teaching hospital is a hospital or medical centre that provides medical education and training to future and current health professionals. Teaching hospitals are almost always affiliated with one or more universities and are often co-located ...

. Industrial, institutional, and National Cancer Institute-sponsored external

peer-reviewed Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review ...

clinical trials Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietar ...

are conducted at City of Hope.

Synthetic human insulin

In 1978, City of Hope researchers Arthur Riggs and

Keiichi Itakura is an organic chemist and a Professor in the Department of Molecular and Cellular Biology at the Beckman Research Institute at City of Hope National Medical Center. Biography Itakura was born in Tokyo, Japan on February 18, 1942. He obtained a Ph ...

, working with

Herbert Boyer Herbert Wayne "Herb" Boyer (born July 10, 1936) is an American biotechnologist, researcher and entrepreneur in biotechnology. Along with Stanley N. Cohen and Paul Berg he discovered a method to coax bacteria into producing foreign proteins, ther ...

of San Francisco-based

biotechnology Biotechnology is the integration of natural sciences and engineering sciences in order to achieve the application of organisms, cells, parts thereof and molecular analogues for products and services. The term ''biotechnology'' was first used b ...

corporation A corporation is an organization—usually a group of people or a company—authorized by the state to act as a single entity (a legal entity recognized by private and public law "born out of statute"; a legal person in legal context) and r ...

Genentech, Inc. Genentech, Inc., is an American biotechnology corporation headquartered in South San Francisco, California. It became an independent subsidiary of Roche in 2009. Genentech Research and Early Development operates as an independent center within ...

, became the first scientists to produce synthetic human insulin. City of Hope licensed patents based on Riggs's and Itakura's work to Genentech. On August 13, 1999, City of Hope sued Genentech for allegedly cheating it out of its fair share of the profits from products based on the Riggs-Itakura patents. On April 24, 2008, the

Supreme Court of California The Supreme Court of California is the highest and final court of appeals in the courts of the U.S. state of California. It is headquartered in San Francisco at the Earl Warren Building, but it regularly holds sessions in Los Angeles and Sacra ...

affirmed the jury's award of $300 million in contractual damages to City of Hope but reversed the award of $200 million in punitive damages.

Hematopoietic cell transplantation

On January 13, 2011, City of Hope performed its 10,000th

hematopoietic stem cell transplantation Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produc ...

, which includes transplants of

bone marrow Bone marrow is a semi-solid tissue found within the spongy (also known as cancellous) portions of bones. In birds and mammals, bone marrow is the primary site of new blood cell production (or haematopoiesis). It is composed of hematopoietic ce ...

peripheral blood stem cells Peripheral blood stem cell transplantation (PBSCT), also called "Peripheral stem cell support", is a method of replacing blood-forming stem cells. Stem cells can be destroyed through cancer treatments such as chemotherapy or radiation, as well as ...

collected by

apheresis Apheresis ( ἀφαίρεσις (''aphairesis'', "a taking away")) is a medical technology in which the blood of a person is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation ...

, and

umbilical cord In placental mammals, the umbilical cord (also called the navel string, birth cord or ''funiculus umbilicalis'') is a conduit between the developing embryo or fetus and the placenta. During prenatal development, the umbilical cord is physiologic ...

stem cells. By 2016, this has grown to over 13,000 stem cell transplants.

National Comprehensive Cancer Network

City of Hope is a founding member of the

(NCCN), a non-profit alliance of 21 U.S. cancer centers. The NCCN publishes clinical practice guidelines for oncological treatment among its member institutions. Member institutions include City of Hope, The University of Texas

MD Anderson Cancer Center The University of Texas MD Anderson Cancer Center (colloquially MD Anderson Cancer Center) is a comprehensive cancer center in Houston, Texas. It is the largest cancer center in the U.S. and one of the original three comprehensive cancer centers ...

, St. Jude Children's Research Hospital/University of Tennessee Cancer Institute,

Fox Chase Cancer Center Fox Chase Cancer Center is a National Cancer Institute-designated Comprehensive Cancer Center research facility and hospital located in the Fox Chase section of Philadelphia, Pennsylvania, United States. The main facilities of the center are loca ...

Philadelphia Philadelphia, often called Philly, is the largest city in the Commonwealth of Pennsylvania, the sixth-largest city in the U.S., the second-largest city in both the Northeast megalopolis and Mid-Atlantic regions after New York City. Sinc ...

, Pennsylvania,

Fred Hutchinson Cancer Research Center The Fred Hutchinson Cancer Center, formerly known as the Fred Hutchinson Cancer Research Center and also known as Fred Hutch or The Hutch, is a cancer research institute established in 1975 in Seattle, Washington. History The center grew out o ...

Seattle Seattle ( ) is a seaport city on the West Coast of the United States. It is the seat of King County, Washington. With a 2020 population of 737,015, it is the largest city in both the state of Washington and the Pacific Northwest regio ...

, Washington, and 16 others.

Facilities

Patient Care Facilities

City of Hope's main campus in Duarte has several treatment facilities for inpatient and outpatient care, including the Helford Clinical Research Hospital, Michael Amini Transfusion Medicine Center, the Geri and Richard Brawerman Center for Ambulatory Care and the Women's Center. In addition to the Duarte campus facilities, City of Hope also has community practice clinics located in Antelope Valley, Arcadia, Colton, Corona, Glendora, Mission Hills, Palm Springs, Pasadena, Rancho Cucamonga, Santa Clarita, Simi Valley, South Pasadena, West Covina, Torrance, and Newport Beach. City of Hope is planning to build a $200 million cancer center, which would anchor a future medical campus south of the Orange County Great Park in Irvine in collaboration with FivePoint Holdings. City of Hope is accredited by the Joint Commission, a private body which accredits over 17,000 health care organizations and programs in the United States.

Beckman Research Institute of City of Hope

Beckman Research Institute of City of Hope is one of six research facilities established by funding from the

Arnold and Mabel Beckman Arnold Orville Beckman (April 10, 1900 – May 18, 2004) was an American chemist, inventor, investor, and philanthropist. While a professor at California Institute of Technology, he founded Beckman Instruments based on his 1934 invention of th ...

Foundation. Its primary focus is research in the areas of

cancer Cancer is a group of diseases involving abnormal cell growth with the potential to invade or spread to other parts of the body. These contrast with benign tumors, which do not spread. Possible signs and symptoms include a lump, abnormal b ...

, and

. The institute shelters the City of Hope Irell & Manella Graduate School of Biological Sciences. Research conducted at the institute has contributed to discoveries in the areas of

recombinant DNA technology Molecular cloning is a set of experimental methods in molecular biology that are used to assemble recombinant DNA molecules and to direct their replication within host organisms. The use of the word ''cloning'' refers to the fact that the metho ...

gene therapy Gene therapy is a medical field which focuses on the genetic modification of cells to produce a therapeutic effect or the treatment of disease by repairing or reconstructing defective genetic material. The first attempt at modifying human DN ...

and

monoclonal antibodies A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell Lineage made by cloning a unique white blood cell. All subsequent antibodies derived this way trace back to a unique parent cell. Monoclonal antibodies ca ...

Center for Biomedicine & Genetics

City of Hope Center for

Biomedicine Biomedicine (also referred to as Western medicine, mainstream medicine or conventional medicine)

Genetics Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar wor ...

is a manufacturing facility specializing in the production of

pharmaceutical A medication (also called medicament, medicine, pharmaceutical drug, medicinal drug or simply drug) is a drug used to diagnose, cure, treat, or prevent disease. Drug therapy (pharmacotherapy) is an important part of the medical field and re ...

-grade materials. The center also assists

clinical investigator A clinical investigator involved in a clinical trial is responsible for ensuring that an investigation is conducted according to the signed investigator statement, the investigational plan, and applicable regulations; for protecting the rights, safe ...

s with

translational research Translational research (also called translation research, translational science, or, when the context is clear, simply translation) is research aimed at translating (converting) results in basic research into results that directly benefit humans. ...

and clinical trials.

Irell & Manella Graduate School of Biological Sciences

The graduate school at City of Hope; the school is housed within the Arnold and Mabel Beckman Center for Cancer Immunotherapeutics & Tumor Immunology.

Patient housing

City of Hope has 40 temporary, on-site residential housing units for patients and their caregivers, with integrated

hospice Hospice care is a type of health care that focuses on the palliation of a terminally ill patient's pain and symptoms and attending to their emotional and spiritual needs at the end of life. Hospice care prioritizes comfort and quality of life by ...

and

palliative Palliative care (derived from the Latin root , or 'to cloak') is an interdisciplinary medical caregiving approach aimed at optimizing quality of life and mitigating suffering among people with serious, complex, and often terminal illnesses. Wit ...

care.

Fundraising

City of Hope secures funding from a mixture of sources, including patient revenue, private donations, foundation support and federal research grants. Annual

fundraising Fundraising or fund-raising is the process of seeking and gathering voluntary financial contributions by engaging individuals, businesses, charitable foundations, or governmental agencies. Although fundraising typically refers to efforts to gathe ...

events include Walk for Hope (a multi-city charity fundraising walk), Concert for Hope (a fundraising concert featuring celebrity musicians), and the City of Hope Celebrity

Softball Softball is a game similar to baseball played with a larger ball on a smaller field. Softball is played competitively at club levels, the college level, and the professional level. The game was first created in 1887 in Chicago by George Hanc ...

Challenge, held in

Nashville, Tennessee Nashville is the capital city of the U.S. state of Tennessee and the county seat, seat of Davidson County, Tennessee, Davidson County. With a population of 689,447 at the 2020 United States census, 2020 U.S. census, Nashville is the List of muni ...

. City of Hope maintains eight regional fundraising offices in various cities throughout the United States, including

Palm Desert Palm Desert is a city in Riverside County, California, United States, in the Coachella Valley, approximately east of Palm Springs, northeast of San Diego and east of Los Angeles. The population was 48,445 at the 2010 census. The city has been ...

Phoenix Phoenix most often refers to: * Phoenix (mythology), a legendary bird from ancient Greek folklore * Phoenix, Arizona, a city in the United States Phoenix may also refer to: Mythology Greek mythological figures * Phoenix (son of Amyntor), a ...

San Diego San Diego ( , ; ) is a city on the Pacific Ocean coast of Southern California located immediately adjacent to the Mexico–United States border. With a 2020 population of 1,386,932, it is the List of United States cities by population, eigh ...

San Francisco San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of Ca ...

, Seattle,

Chicago (''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = Country , subdivision_name ...

, Philadelphia, and Ft. Lauderdale, Florida. The hospital also fundraises using giving days. In 2016, Doctors' Day allowed patients to thank doctors by giving in their name. More than $9000 was raised through 60 gifts. In 2017, City of Hope was planning a Bone Marrow Transplant Reunion Day and Survivors Day. The hospital also participates in #

GivingTuesday GivingTuesday, often stylized as #GivingTuesday for the purposes of hashtag activism, is the Tuesday after Thanksgiving in the United States. It is touted as a "global generosity movement unleashing the power of people and organizations to transf ...

. In 2015, the first time the hospital used the fundraiser, almost $120,000 were raised from 681 gifts. In 2016, those numbers rose to almost $200,000 from more than 1500 gifts. In January 2017 City of Hope received a donation of more than $50 million to establish the Wanek Family Project for Type 1 Diabetes at City of Hope.

Affiliations

City of Hope is affiliated with the following institutions: *

Association of Community Cancer Centers Association may refer to: *Club (organization), an association of two or more people united by a common interest or goal *Trade association, an organization founded and funded by businesses that operate in a specific industry *Voluntary associatio ...

(founding member) * National Bone Marrow Transplantation Research Network (founding member) * National Gene Vector Laboratory *

Southern California Islet Cell Consortium Southern may refer to: Businesses * China Southern Airlines, airline based in Guangzhou, China * Southern Airways, defunct US airline * Southern Air, air cargo transportation company based in Norwalk, Connecticut, US * Southern Airways Express, ...

(SC-IC) * Islet Cell Transplant Center *

Juvenile Diabetes Research Foundation JDRF is a nonprofit 501(c)(3) organization that funds type 1 diabetes (T1D) research, provides a broad array of community and activist services to the T1D population and actively advocates for regulation favorable to medical research and approval o ...

Recognition

* In 2015, City of Hope was ranked as one of the "Best Hospitals" in cancer (#13) and gynecology (#41) by '' U.S. News & World Report''. * In 2009, City of Hope was listed among eight preferred cancer hospitals in the May/June issue of ''AARP Magazine'', which published the results of a survey of doctors from throughout the United States conducted by

Consumers' Checkbook ''Consumers' Checkbook''/Center for the Study of Services (doing business as ''Consumers’ CHECKBOOK'') is an independent, nonprofit consumer organization. It was founded in 1974 in order to provide survey information to consumers about vendors an ...

, a

Washington, D.C. ) , image_skyline = , image_caption = Clockwise from top left: the Washington Monument and Lincoln Memorial on the National Mall, United States Capitol, Logan Circle, Jefferson Memorial, White House, Adams Morgan, ...

-based non-profit health care provider rating service. Sampled doctors were asked "where they were most likely to send patients with extremely difficult cases". * As of 2016, 52 City of Hope physicians are currently listed as "Top Doctors" by Castle Connolly Medical Ltd., as nominated by their peers in the medical profession. Castle Connolly is an independent company that surveys thousands of medical professionals in the United States and publishes the results in an annual consumer guide, '' America's Top Doctors''. * In December 2015,

Charity Watch CharityWatch, formerly known as the American Institute of Philanthropy (AIP), is a 501(c)(3) nonprofit organization in Chicago, created in the United States by Daniel Borochoff in 1992, to provide information about charities' financial efficiency ...

rates City of Hope / Beckman Research Institute charity an "A−" grade.Charity Rating Guide and Watchdog Report, Volume Number 59, December 2011 * In 2016, Charity Navigator gave City of Hope a 4 stars – its highest rating – for the 11th consecutive year.

Grants

National Cancer Institute grants

* Specialized Program of Research Excellence (SPORE) grant for translational research studies for

Hodgkin Hodgkin is a surname. Notable people with the surname include: * Alan Lloyd Hodgkin (1914–1998), British physiologist and biophysicist * Dorothy Hodgkin (1910–1994), British chemist who received the Nobel Prize in Chemistry in 1964, wife of Th ...

and

non-Hodgkin lymphoma Non-Hodgkin lymphoma (NHL), also known as non-Hodgkin's lymphoma, is a group of blood cancers that includes all types of lymphomas except Hodgkin lymphomas. Symptoms include enlarged lymph nodes, fever, night sweats, weight loss, and tiredness. ...

- Five-year, $11.5 million. * Grant to City of Hope's Division of Nursing Research for study of palliative care and quality-of-life concerns for lung cancer patients - Five-year, $13.4 million. * Grant to City of Hope's Division of Cancer Etiology for the California Teachers Study, a survey of over 130,000 public school teachers and administrators to study the link between obesity, physical activity, hormone exposure and cancer - Three-year, $5 million. * Grant to City of Hope's Department of Population Sciences to study genetic susceptibility for secondary malignancies as a result of treatment for cancer survivors - Five-year, $3.4 million.

Other grants

California Institute for Regenerative Medicine The California Institute for Regenerative Medicine (CIRM) was created in 2004 after 59% of California voters approved California Proposition 71: the Research and Cures Initiative, which allocated $3 billion to fund stem cell research in California ...

(CIRM) grants for AIDS-related lymphoma and brain cancer research - $32.5 million. *

National Library of Medicine The United States National Library of Medicine (NLM), operated by the United States federal government, is the world's largest medical library. Located in Bethesda, Maryland, the NLM is an institute within the National Institutes of Health. Its ...

National Institute of Diabetes and Digestive and Kidney Diseases The National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is part of the United States National Institutes of Health, which in turn is part of the Department of Health and Human Services. NIDDK is approximately the fifth-largest ...

grant to City of Hope's Department of Information Sciences to serve as coordinating center for distribution of

islet cell The pancreatic islets or islets of Langerhans are the regions of the pancreas that contain its endocrine (hormone-producing) cells, discovered in 1869 by German pathological anatomist Paul Langerhans. The pancreatic islets constitute 1–2% of ...

s and

intestinal The gastrointestinal tract (GI tract, digestive tract, alimentary canal) is the tract or passageway of the digestive system that leads from the mouth to the anus. The GI tract contains all the major organs of the digestive system, in humans ...

stem cells In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type o ...

- $17 million. *

National Institute of Environmental Health Sciences The National Institute of Environmental Health Sciences (NIEHS) conducts research into the effects of the environment on human disease, as one of the 27 institutes and centers of the National Institutes of Health (NIH). It is located in the Rese ...

grant to study

ultraviolet Ultraviolet (UV) is a form of electromagnetic radiation with wavelength from 10 nanometer, nm (with a corresponding frequency around 30 Hertz, PHz) to 400 nm (750 Hertz, THz), shorter than that of visible light, but longer than ...

light damage and its effect on

mutagenesis Mutagenesis () is a process by which the genetic information of an organism is changed by the production of a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be achieved experimentally using la ...

- $2 million.

Contracts

National Heart, Lung, and Blood Institute The National Heart, Lung, and Blood Institute (NHLBI) is the third largest Institute of the National Institutes of Health, located in Bethesda, Maryland, United States. It is tasked with allocating about $3.6 billion in FY 2020 in tax revenue to ...

(NHLBI) contract to facilitate

stem cell research In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type o ...

from laboratory to clinical study; focus on development and manufacture of stem cell therapies—five-year, $8.6 million.

References

External links

City of Hope Official Website
{{DEFAULTSORT:City Of Hope National Medical Center Cancer hospitals Cancer organizations based in the United States Duarte, California History of biotechnology Hospitals in Los Angeles County, California Medical research institutes in California 1913 establishments in California Organizations established in 1913 NCI-designated cancer centers